Pseudopodoces humilis (Tibetan ground-tit): 102104562
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Entry
102104562 CDS
T02921
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
phi
Pseudopodoces humilis (Tibetan ground-tit)
Pathway
phi00270
Cysteine and methionine metabolism
phi00480
Glutathione metabolism
phi01100
Metabolic pathways
phi01240
Biosynthesis of cofactors
phi04216
Ferroptosis
Module
phi_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
phi00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
102104562 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
102104562 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
102104562 (GCLC)
Enzymes [BR:
phi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
102104562 (GCLC)
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Paralog
GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
102104562
NCBI-ProteinID:
XP_005518158
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All DBs
Position
Unknown
AA seq
636 aa
AA seq
DB search
MGLLSQGSPLSWEETRRYAEHVRRHGILQFLHIYRALRDRHKDVLKWGDEVEYMLVKFDH
ENKKVRLVLCGEEVVQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTLPEYQPTPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPLFKDKNTPSPFIETFPNDDGEAAKAAKPDYIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKNSHYRISKSRYDSIDSYLSECGEKYNDIDLTIDKDIYEHLI
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDICKGGNAVVDGCGSAQNGTGTDTEEYTLMSIDTIINGKEGVFPGLIPILN
SYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSVITDEINY
SLMWKCNQIAQGQAECPELLGVGFNKKQSGNKTDSL
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcgcagggctcgccgctgagctgggaggagacgcggcggtacgcggag
cacgtgcggcggcacggcatcctccagttcctccacatctaccgcgccctgcgcgaccgc
cacaaggacgtgctcaagtggggcgacgaggtggaatatatgttggtaaaatttgaccat
gaaaataagaaagtgcgtttggtactctgtggtgaagaagttgttcaaacactgcaagac
aaaggggagaaggtaaaccccaatcacccaacactctggagaccagaatatggaagttac
atgattgaaggaacacctggacagccatatggaggaaccatgtctgaattcaatactgtt
caagacaacatgaggaaaagacggcaagaggctgcttctgtactcaaagaaaatgaggct
gtttgcacagtgacatcatttccaaggttagggtgccctgggtttacactgccagaatat
cagccaacaccagtagaaggaggagcttcaaaatccctcttttttccagatgaagccatc
aataaacatcctagatttagtacactgaccagaaatattcgacaccgaagaggagagaag
gttgtgataaatgtaccactatttaaggataagaacacgccatcacctttcattgaaaca
tttcctaatgatgatggggaagcagcaaaggcagctaagccggactacatatatatggat
gctatgggttttggaatgggaaactgttgtctccaggtaacatttcaagcttgcagcatt
tctgaagcaaggtatctctatgatcagctagctacaatttgtcccattgtgatggcgttg
agtgctgcatctcccttctacagaggctacgtgtctgacattgactgtcgctggggagtg
atctcagcttccgtggatgatcgaacgcgggaggagagagggctagagccactgaagaac
agccattatagaatcagtaaatccagatatgattccatagacagttatctatctgaatgt
ggtgagaaatacaatgacattgatttgacaatagacaaagatatctacgagcacctaata
aaggaaggtattgaccaccttttggcacagcatattgcacacttgttcattcgagaccca
ttgactttgtttgaggagaaaatacatctagatgatgcaaatgaatccgaccattttgag
aatattcagtctacaaactggcagacgatgagatttaagccaccacctccaaattcagat
attggatggagagtggaattcagacctatggaggtccagttaacagactttgaaaactct
gcatatgttgtgtttgtggtattgctaaccagagtgattctgtcatataaactggatttt
ctcattcctttgtccaaggtggatgaaaacatgaaggtggcccagaaaagagatgctgta
cgacagggaatgttctacttcagaaaagatatatgcaaaggtggaaatgctgttgtggat
ggatgtggctctgcccagaatggaacaggcaccgacacagaagagtacaccttaatgagc
attgatacaattatcaatgggaaggaaggagtctttcctggtttgatccctattttgaat
tcctatcttgaaaacatggaagtggatgtggacacaagatgcaccatcctaaactatctg
aagctaattaaaaagagagcttctggagaattaatgacagttgctcgatggatgagggaa
ttcattgcacagcatccggactacaagcaagacagtgtgataactgatgaaattaattac
agccttatgtggaaatgcaaccaaatcgctcaaggccaggcagaatgtcctgaactattg
ggggtaggatttaataagaaacaaagtggaaacaaaactgactctttgtaa
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