Pseudothermotoga hypogea: AJ81_00050
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Entry
AJ81_00050 CDS
T04277
Name
(GenBank) D-alanyl-alanine synthetase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
phy
Pseudothermotoga hypogea
Pathway
phy00470
D-Amino acid metabolism
phy00550
Peptidoglycan biosynthesis
phy01100
Metabolic pathways
phy01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
phy00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
AJ81_00050
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AJ81_00050
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AJ81_00050
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
phy01011
]
AJ81_00050
Enzymes [BR:
phy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
AJ81_00050
Peptidoglycan biosynthesis and degradation proteins [BR:
phy01011
]
Precursor biosynthesis
Amino acid ligase
AJ81_00050
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Gene cluster
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Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp_3
ATP-grasp_4
CPSase_L_D2
ATP-grasp
Motif
Other DBs
NCBI-ProteinID:
AJC72852
UniProt:
A0A0X1KNQ9
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All DBs
Position
10662..11555
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AA seq
297 aa
AA seq
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MKIAVLMGGVSREREISLRSGENVVKALKKLGHEVVPIDVKEDFFLVLPSLKQFDLVFIA
LHGKFGEDGTVQALLDWIGVPYTGSGVLASALCFDKLMTYRIVEKFVPVPEYTVIDKPTR
ESPFGFPCVLKPRREGSSIGVHICDNAEELEHYSQIELSLYGELVLQRYVRGRELTASLI
EMDGELRILPILELRPRRRFYDYIAKYTPNMTEFVLPAPLTEEEYRAVCESCLKAFKACE
CKGFARIDGILKDGIFYFLEINTIPGMTDLSDMPASARAAGMSFEDLIDAIVKTVRR
NT seq
894 nt
NT seq
+upstream
nt +downstream
nt
ttgaagatagcagtcttgatgggtggtgtgtctcgagaacgggagatctcgttgagaagc
ggtgaaaacgttgtcaaagctctgaagaagctcggccatgaggttgtcccaatagatgtg
aaggaagacttttttctcgttttgccttcactcaaacaattcgatcttgtcttcatcgca
cttcatgggaagttcggcgaagatgggaccgttcaggccctgctggattggatcggtgtg
ccgtacacgggctctggcgtactcgcgagcgccctgtgcttcgacaagttaatgacctac
aggatcgtcgagaagttcgttccggttcctgagtacaccgtcatcgacaaacccacaaga
gagtctccgttcggttttccttgcgttttgaaaccacgcagagaaggttccagcataggt
gtgcacatctgcgacaatgctgaagagctcgaacattattcgcaaatagagttgagcctt
tacggagagctggtcttgcaacgttacgttcggggcagggaactcacggcatcactgatc
gagatggacggagaattgagaatcctacccatactcgaactcaggccgaggcgtaggttc
tatgactacatcgccaagtacacaccgaacatgacggagttcgttctacccgctccactc
accgaggaagagtacagagcggtctgtgaatcttgcttgaaggctttcaaagcgtgcgag
tgcaagggctttgcgaggatcgatgggattctgaaggatgggattttttattttctggag
atcaacaccatacccggtatgacagatctgagcgacatgccagcctcggcgcgtgccgcg
ggaatgagctttgaagatttgatagatgcgatagtgaagacggtgagaagatga
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