Scheffersomyces stipitis: PICST_68770
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Entry
PICST_68770 CDS
T01023
Symbol
LEU4
Name
(RefSeq) 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
pic
Scheffersomyces stipitis
Pathway
pic00290
Valine, leucine and isoleucine biosynthesis
pic00620
Pyruvate metabolism
pic01100
Metabolic pathways
pic01110
Biosynthesis of secondary metabolites
pic01210
2-Oxocarboxylic acid metabolism
pic01230
Biosynthesis of amino acids
Module
pic_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
pic00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
PICST_68770 (LEU4)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PICST_68770 (LEU4)
Enzymes [BR:
pic01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
PICST_68770 (LEU4)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-GeneID:
4850963
NCBI-ProteinID:
XP_001387341
JGI:
68770
UniProt:
A3GFB4
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Position
1:569514..571337
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AA seq
571 aa
AA seq
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MLKDPSTKYAAFKGVKLDKRTWPSKSITKAPRWLSTDLRDGNQALPDPMSVEEKKEYFHK
LLEIGFKEIEVSFPSASQTDFDFTRYAVENAPDDVSIQVLTQSREPLIRRTVESVKGAKK
ATIHTYLATSDVFRDVVFNMSQEDAIAKAIETTKLVKSLTKDDPEMQETEWTLEFSPECF
SDTPTEFAVQICEAVKNVWEPTVENPIIFNLPATVEVASPNVYADQIEYFATHISEREKV
CISLHAHNDRGCGVAASELGLLAGGDRVEGCLFGNGERTGNVDLITVALNMYTNGVAPEL
DFSEIEKLIEVSERCNKIPVHPRAPYSGSLVVCAFSGSHQDAIKKGFSKAEARAARGDTK
WAIPYLPLDPKDIGRNYEAVIRVNSQSGKGGAAWVILRSLGLDLPRHLQVVFSGIVQERA
DSLGRELKSEEIAALFNEQYCSTSNLSVKDFEITKRKNAPENKDREIFAVLQAGSKTVDV
SGQGNGPISAFVDAISKKYGVSFEVVNYSEHSLGSGTQSKAATYIELAYNNSNNEHVTKW
GCGINTDVSQASMEAILSVVNSLIDSKEINL
NT seq
1716 nt
NT seq
+upstream
nt +downstream
nt
atgttaaaggatccttccaccaaatatgctgcctttaaaggagtcaagttggacaagaga
acctggccctcaaagtctatcaccaaggctcctaggtggttatctactgatttaagagat
ggtaaccaagcgttgcctgatcccatgtctgtcgaagagaagaaggagtattttcacaag
ctcttggagatcggattcaaagaaatcgaggtatctttcccttctgcatctcaaacagat
tttgacttcaccagatatgctgtggagaacgcaccagatgatgtttcgatccaagttttg
actcagtctagagaacctttgatcagaagaactgttgaatccgtaaagggtgctaagaag
gctaccatacatacatacttggctacttctgacgttttccgtgatgttgttttcaacatg
tcacaagaagatgcaattgccaaagccattgaaactaccaagttggtcaagtctttgaca
aaggacgatccagaaatgcaggaaaccgagtggaccttggaattctctcctgaatgcttc
tcagatactcctaccgaatttgctgtgcaaatttgtgaagcagtcaagaacgtctgggag
ccaactgtagagaatcctatcattttcaacttgccagctaccgttgaagttgcttctcca
aacgtctacgctgaccagatcgaatactttgctacccacatttccgaacgtgaaaaggtg
tgtatttctcttcatgctcacaatgaccgtggctgcggtgttgctgcctcggaattaggt
ttattggctggcggagacagagtcgaaggttgtttgtttggaaacggtgaaagaaccggt
aacgtagacttgatcactgttgctctcaacatgtacaccaatggagttgcaccggagttg
gacttttcagaaatcgaaaagctcatcgaggtcagtgaaagatgtaacaaaatcccagtt
cacccaagagctccatactctggatccttggtcgtttgtgccttctctggttctcaccaa
gatgctatcaagaagggattctccaaggctgaagccagagctgctaggggtgacaccaaa
tgggccattccatacttgccattagaccctaaggatatcggtagaaactacgaggccgtt
atcagagtcaactctcaatctggtaagggaggtgctgcctgggtcatcttgagatctctc
ggcttggacttgccaagacacttgcaagttgtcttttctggtattgttcaggaaagagct
gactctttgggtagagaattgaagtctgaagagattgccgctttgttcaacgagcagtac
tgctctacttccaacttgtctgtcaaggacttcgagataactaagagaaagaatgctcca
gagaacaaggaccgtgagatctttgctgtcttgcaggctggatccaagaccgttgacgtc
agtggacaaggtaacggacctatttcggcctttgtggatgccatatccaagaaatacggt
gtttcctttgaagtcgtcaactacagtgaacacagtttaggcagtggtacccagagtaag
gctgctacttacattgagttagcctacaacaactctaacaacgagcatgttacaaagtgg
ggatgcggcattaacacagatgtgtcgcaggcttcgatggaggccattctttctgttgtg
aactcattgattgatagcaaggaaattaatttgtag
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