Paramuribaculum intestinale: NF347_10275
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Entry
NF347_10275 CDS
T09294
Name
(GenBank) bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase
KO
K01798
Alr-MurF fusion protein [EC:
5.1.1.1
6.3.2.10
]
Organism
pii
Paramuribaculum intestinale
Pathway
pii00300
Lysine biosynthesis
pii00470
D-Amino acid metabolism
pii00550
Peptidoglycan biosynthesis
pii01100
Metabolic pathways
pii01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pii00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NF347_10275
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
NF347_10275
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NF347_10275
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NF347_10275
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
pii01011
]
NF347_10275
Enzymes [BR:
pii01000
]
5. Isomerases
5.1 Racemases and epimerases
5.1.1 Acting on amino acids and derivatives
5.1.1.1 alanine racemase
NF347_10275
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NF347_10275
Peptidoglycan biosynthesis and degradation proteins [BR:
pii01011
]
Precursor biosynthesis
Amino acid ligase
NF347_10275
Racemase
NF347_10275
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ala_racemase_N
Ala_racemase_C
Mur_ligase_M
PB1
Motif
Other DBs
NCBI-ProteinID:
WLT41356
LinkDB
All DBs
Position
2270298..2272775
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AA seq
825 aa
AA seq
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MNYKISRIAETIHASLPSPADPDHEISILLTDSRSLTYPDQSIFFAIRTRNNDGHRYMRD
LYDRGVRHFVARHIPDDMASATDAVILLVPSVTRALQDLARAHRSRFDIPVVGITGSRGK
TTVKEWLYQLLSSDYSIVRSPRSYNSQIGVPLSIWELDTDTTMAIFEAGISLPDEMTALQ
GIIKPNIGIITNIGPEHADGFTSLRTKCDEKVILMRDCDVIIYNGDDRVISEAVSEACIP
AKEIAWSTRDSDRPLFISAIRRHRETTDIDFSYLRTDGSVTIPFTSDADIQNAIHCLALM
LYLNRPADITASRISQLAPVATRMEVKEGVNDCLVIYDAYTSDLNSLQPALDFLNRRRTG
RRSVTAIISDVMHETLEPQRLYREVARLLTQRGVDRVIGVGEEISANSRYFPADSRFFPS
TSVMLSEMSADDFDRELVLVKGASRFHFEMIAEMLEARQHETVLEVNLDALVSNFNLYRS
MLRPTTGIICMVKASGYGAGSYELAKTLQAQGAAYMAVAVLDEGVELREAGITMPVMVMN
PHVANYKTMFAYRLEPEVYSFGILREIIREGEKCGITDFPVHIKLDTGMHRLGFIPEEIP
ELIDLLRRQKVVRPHSLFSHLATADCPHLNSYTEGQLKLFDSMCAQIQSAFSHYIMRHIL
NSAGIARYPSHQYDMVRLGIGLYGVATLPGGEPAGLRTVSSLRTVIISIREWPAGTTIGY
GCRGVCTRRSRIATIPVGYADGIDRHLGNGGMRVWINGHRCPSIGNICMDACMIDVTDAD
CQVGDRVEIFGDNVPVEDLSDVLDTIPYEMLTSVSTRVKRIYYRE
NT seq
2478 nt
NT seq
+upstream
nt +downstream
nt
atgaactacaagatatcgcggatagccgaaactatccatgcatcgctcccctccccggcc
gaccccgaccatgaaatctcgatactgctcaccgacagccgatcgctgacctatccggat
cagtcgatattcttcgccatacgcacccgcaacaacgacgggcaccgctatatgcgcgat
ctgtacgaccgcggggtgagacacttcgtggcgcggcacattcccgacgacatggcctcg
gcaactgacgccgtgatattgctcgtgccgagcgtcacacgcgcccttcaggatcttgcc
cgcgcccaccgcagccggtttgacataccggtggtgggcatcaccggctcccgcggcaag
accaccgtcaaggagtggctctatcaactgctgtcgtcggactactcgatagtcagatcg
ccgcgcagctacaactcccagatcggagtgcccctgtcgatatgggaactcgacaccgac
accaccatggccatcttcgaggccggcatatcgctccccgacgagatgaccgccctgcaa
ggcatcatcaagcccaacataggcataatcaccaacatcgggccggagcatgccgacgga
ttcacttcgctgcgcacgaaatgcgacgaaaaggtgatattgatgcgcgactgcgacgtg
atcatctacaacggcgatgaccgggtgatcagcgaagccgtcagcgaggcctgcataccg
gccaaagagatcgcatggtcgacacgcgacagcgaccggccgctgttcatatcggccata
cgacgccaccgcgaaacgaccgacattgacttctcctatctgcgcaccgacggctctgtg
acgataccgttcacttccgacgccgacatacagaacgccatccactgtctggcgctgatg
ctgtatctcaaccgcccggccgacatcaccgcctcgcggatatcacagcttgcgccggtg
gccacgcgaatggaggtgaaggagggcgtgaacgactgcctcgtgatatatgacgcctac
acctccgatctcaactccctgcagccggcactcgactttctgaacaggaggcgcaccggc
cggcgatccgtcactgcgataatctctgacgtgatgcacgaaaccctcgagccgcaacgc
ctctaccgcgaggtggcccgactgctgacacagcgcggagtggatcgcgtgataggcgtc
ggcgaagagatctcggccaactcccgctattttccagccgactcccgcttcttcccttcg
acctcggtgatgctctcggagatgtcggccgacgacttcgaccgcgagctggtgctcgtc
aaaggcgcctcgcgttttcatttcgaaatgattgccgagatgctcgaggcccgtcagcac
gaaaccgtactggaggtaaatctcgacgctctggtatccaacttcaacctctaccgctcg
atgctccgccccaccaccggtataatatgcatggtcaaggcctcaggctacggagccggc
tcctacgaactggccaagacactccaggcgcagggcgcggcatatatggccgtggctgtg
ctcgacgagggcgtggaactgcgcgaggccggcatcaccatgccggtaatggtgatgaac
cctcacgtggccaactacaagacgatgtttgcctatcggctagaaccggaggtgtactcc
ttcggcatacttcgcgaaataatccgcgaaggtgagaaatgcggcatcaccgatttcccg
gtacatatcaagctcgacaccggaatgcaccgccttggcttcatacccgaggagatcccc
gagctgatcgacctgctgcgtcgccagaaggtggtgcgtccccactcgttgttctcgcat
ctggccacggccgactgccctcatctcaactcctataccgaaggacagctgaaactgttt
gacagcatgtgcgcgcagatacagagtgccttcagccactacatcatgcgccacatactc
aactcggccggcatagcgcggtatccctctcaccagtacgacatggtgcgcctcggcatc
ggactgtatggcgtcgccaccctgcccggcggcgaaccggcaggtctgcgcaccgtatcg
tcgctgcgcaccgtcatcatctccatacgcgaatggcctgccggcaccaccataggctac
ggctgccgcggagtgtgcacgcgccgctcgcgcatagccacgatcccggtgggatatgcc
gacggcatcgaccgccatctcggcaacggcggcatgagagtgtggatcaacggccaccgc
tgtccgtcgataggcaatatatgcatggacgcatgcatgatcgacgtcaccgacgccgac
tgtcaggtgggggaccgggtggagatcttcggcgacaatgtgcctgtcgaggatctgtcg
gacgtgctcgacaccatcccctacgagatgctcacatccgtaagcacccgagtgaagcgc
atttactaccgcgaataa
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