Paramormyrops kingsleyae: 111860453
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Entry
111860453 CDS
T05788
Symbol
pik3ca
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
pki
Paramormyrops kingsleyae
Pathway
pki00562
Inositol phosphate metabolism
pki01100
Metabolic pathways
pki04012
ErbB signaling pathway
pki04068
FoxO signaling pathway
pki04070
Phosphatidylinositol signaling system
pki04081
Hormone signaling
pki04140
Autophagy - animal
pki04150
mTOR signaling pathway
pki04210
Apoptosis
pki04218
Cellular senescence
pki04370
VEGF signaling pathway
pki04510
Focal adhesion
pki04620
Toll-like receptor signaling pathway
pki04625
C-type lectin receptor signaling pathway
pki04810
Regulation of actin cytoskeleton
pki04910
Insulin signaling pathway
pki04914
Progesterone-mediated oocyte maturation
pki05100
Bacterial invasion of epithelial cells
pki05132
Salmonella infection
pki05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
pki00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
111860453 (pik3ca)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
111860453 (pik3ca)
04370 VEGF signaling pathway
111860453 (pik3ca)
04068 FoxO signaling pathway
111860453 (pik3ca)
04070 Phosphatidylinositol signaling system
111860453 (pik3ca)
04150 mTOR signaling pathway
111860453 (pik3ca)
09133 Signaling molecules and interaction
04081 Hormone signaling
111860453 (pik3ca)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
111860453 (pik3ca)
09143 Cell growth and death
04210 Apoptosis
111860453 (pik3ca)
04218 Cellular senescence
111860453 (pik3ca)
09144 Cellular community - eukaryotes
04510 Focal adhesion
111860453 (pik3ca)
09142 Cell motility
04810 Regulation of actin cytoskeleton
111860453 (pik3ca)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
111860453 (pik3ca)
04625 C-type lectin receptor signaling pathway
111860453 (pik3ca)
09152 Endocrine system
04910 Insulin signaling pathway
111860453 (pik3ca)
04914 Progesterone-mediated oocyte maturation
111860453 (pik3ca)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
111860453 (pik3ca)
09171 Infectious disease: bacterial
05132 Salmonella infection
111860453 (pik3ca)
05100 Bacterial invasion of epithelial cells
111860453 (pik3ca)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pki04131
]
111860453 (pik3ca)
Enzymes [BR:
pki01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
111860453 (pik3ca)
Membrane trafficking [BR:
pki04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
111860453 (pik3ca)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_rbd
PI3K_C2
PI3K_p85B
DUF2321
ABC1
Ribosomal_S15
Motif
Other DBs
NCBI-GeneID:
111860453
NCBI-ProteinID:
XP_023699961
Ensembl:
ENSPKIG00000023411
LinkDB
All DBs
Position
Unknown
AA seq
1068 aa
AA seq
DB search
MPPRPSSGELWGIHLMPPRILVDCLLPNGMIVALECLREATLITIKHELFKEARKYPLHQ
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDLEVQDFRRNILNVCKDAVDLRDANGPHSRALYVYPPNVESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQCKYILKVCGCDEYLLEKYPLSEYKYIRSCIMLGRMPNLMLMAKESLYSQLPMD
TFTMPSYARRISTATPYMNGEASCKTLWSISSTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLQYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVAGSNPNKETPCLELEFDFF
NCPVKFPDMATVEEHANCTISRELGLNYCQSGLSNRLVRDNALTDNDTEQLCQVCNRDPL
SEITEQEKDFLWRHRYYCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDLAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
NT seq
3207 nt
NT seq
+upstream
nt +downstream
nt
atgccgccgaggccatcatcgggagagctatggggaatccatttgatgcccccacggatt
ctggtggactgtcttctgcccaatgggatgatcgtcgcgttggagtgcctccgagaggcc
acgcttatcaccattaagcatgaacttttcaaagaagcacggaagtaccctctgcatcag
ctgctacaggaggagacgtcctacatcttcgtcagtgtcacccaggaagcagagagggag
gagttttatgatgaaaccagaagactttgtgatctcaggctctttcagcctttcctaaaa
gttattgaacctgttggtaacagggaagagaagattctgaacagagaaattgggtttgca
atcggtatgcctgtatgcgagtttgacttggtgaaggatcttgaagttcaggacttcagg
agaaacatcctgaacgtttgtaaagacgcagtggacctcagagatgcgaatgggcctcac
agtcgcgcgttatacgtttaccctcccaacgttgaatcttcatcagaacttccaaaacac
atctacaataaacttgataaaggtcaaataattgttgtgatttgggtaatagtctccccc
aacaatgacaagcagaaatatacactcaaaatcaaccatgactgtgttcctgagcaagtg
atagcagaggctatccgcaagaagaccaggagtatgctgctgtcgccagaacagctcaag
atgtgcgtgcaggagtaccagtgcaagtacatcctcaaggtttgtggctgtgatgagtac
ctgctggaaaagtaccccctgagtgaatacaagtacataaggagctgtattatgctcggt
cggatgccaaacctaatgttaatggcgaaagagagcctctactcccagttacccatggat
acgttcaccatgccatcctacgcccgccgcatctccactgccacaccctacatgaatggc
gaggcctcctgcaagaccctgtggagtatcagcagcaccctgaggatacggatcctctgt
gcgacatacgtcaacgtaaacattcgagacatagataagatttacgtgaggactggaata
taccacgggggagagcagatgtgtgacaatgtgaacacacagcgtgtgccgtgttctaac
ccgaggtggaatgagtggctccagtatgacatgtacatccccgatattccccgtgcggct
cgtctctgtctttctatctgctctgtcaaaggaaggaaaggggcgaaagaggagcactgt
ccacttgcatgggggaatgtgaacctctttgattatacacatactcttgtctcggggaaa
atggcactcaacctatggccagtgcctcatgggcttgaagatctccttaatccgataggt
gtcgcaggatccaacccaaacaaggaaactccttgccttgagctggaattcgatttcttc
aactgcccagtgaagttcccagacatggcaacagtcgaggaacatgcaaactgcaccata
tccagagagctcggcctcaattattgccagtccggactgagcaatagattggtgcgagac
aatgctctaacagacaatgatacggagcagctatgccaggtgtgcaacagagaccctcta
tctgagatcactgagcaggagaaggacttcctgtggcgacaccgatattattgtgtgaat
atgccagaaattctgcctaagatcctgcttgcagtaaagtggaactcaagagatgaagta
gcacagatgtattgccttctgaaagactggccagcaataaagccagaacaagccatggaa
ttgctggattgcaactacccagacccaatgatccgggattttgctgttaggtgtcttgag
aagtatctgacagatgacaaactctcacagtacctcattcagcttgtacaggtcctaaaa
tatgagcagtacctcgataatccactggtgcgatttctgcttaaaaaagccttgactaat
cagaggatcggacacttctttttttggcacttgaagtctgagatgcataacaaaacagtg
agccaacgcttcgggctgctgctggagtcttactgcagagcatgtgggatgtacctgaaa
cacctgagcagacaggtggaggccatggagaagctgataaacctcacagacatcctcaag
caggagaaaaaagatgagacacagaaggtacaaatgaagtttttagtggaacaaatgaga
aggccagactacatggatgcgctgcagagcttcacatccccactaaaccctgcacaccag
ctaggaaacttacgacttgaagaatgcaggattatgtcatctgccaaaaggcccctgtgg
ctaaactgggaaaaccccgatatcatgtcggagcttctcttccagaacaatgagatcatc
ttcaagaatggggatgatttacggcaagacatgctaactctccagattatcagaataatg
gagaacatttggcagaatcagggtcttgacctcagaatgctgccctatggttgcttgtca
atcggtgactgcgtgggactcattgaagtggtgaggaattcccacaccattatgcagatc
caatgcaagggtggcctgaagggggcgctgcagttcaacagccacactcttcaccagtgg
ctgaaggacaagaataaaggggagatgtatgatctggccattgatttgtttacaaggtcc
tgcgctggttattgtgtagctacctttatcctcgggattggggacagacacaacagtaat
atcatggtaaaagatgatggacagctttttcatatcgattttggacatttcctggatcat
aagaagaagaagtttggctataaacgagaacgagtgccatttgttttaacccaagacttt
ttaatagtgatcagcaaaggaacacaagagtgcactaagaccagagaatttgagaggttt
caagagatgtgctacaaggcttaccttgccatccgacagcatgcaaacctcttcatcaac
ctcttctccatgatgctgggctcgggcatgcctgagctacagtcctttgatgacattgct
tacatccggaagaccttggctctggacaaaacggaacaggaggctctagactacttcatg
aagcagatgaacgatgcacatcatggtggatggacaacaaagatggactggatcttccac
acgattcgacagcatgctttgaactga
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