KEGG   Pipistrellus kuhlii (Kuhl's pipistrelle): 118702109
Entry
118702109         CDS       T07682                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
pkl  Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl04010  MAPK signaling pathway
pkl04015  Rap1 signaling pathway
pkl04218  Cellular senescence
pkl04380  Osteoclast differentiation
pkl04620  Toll-like receptor signaling pathway
pkl04664  Fc epsilon RI signaling pathway
pkl04668  TNF signaling pathway
pkl04750  Inflammatory mediator regulation of TRP channels
pkl04912  GnRH signaling pathway
pkl04935  Growth hormone synthesis, secretion and action
pkl04936  Alcoholic liver disease
pkl05014  Amyotrophic lateral sclerosis
pkl05022  Pathways of neurodegeneration - multiple diseases
pkl05132  Salmonella infection
pkl05135  Yersinia infection
pkl05145  Toxoplasmosis
pkl05161  Hepatitis B
pkl05163  Human cytomegalovirus infection
pkl05167  Kaposi sarcoma-associated herpesvirus infection
pkl05169  Epstein-Barr virus infection
pkl05170  Human immunodeficiency virus 1 infection
pkl05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pkl05417  Lipid and atherosclerosis
pkl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pkl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118702109 (MAP2K6)
   04015 Rap1 signaling pathway
    118702109 (MAP2K6)
   04668 TNF signaling pathway
    118702109 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    118702109 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    118702109 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    118702109 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    118702109 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    118702109 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    118702109 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118702109 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118702109 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    118702109 (MAP2K6)
   05161 Hepatitis B
    118702109 (MAP2K6)
   05163 Human cytomegalovirus infection
    118702109 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118702109 (MAP2K6)
   05169 Epstein-Barr virus infection
    118702109 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118702109 (MAP2K6)
   05135 Yersinia infection
    118702109 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    118702109 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    118702109 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    118702109 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118702109 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    118702109 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    118702109 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pkl01001]
    118702109 (MAP2K6)
Enzymes [BR:pkl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     118702109 (MAP2K6)
Protein kinases [BR:pkl01001]
 Serine/threonine kinases: STE group
  STE7 family
   118702109 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 118702109
NCBI-ProteinID: XP_036263653
LinkDB
Position
Unknown
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKSILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggtctcaaaatcccaaaggaagcattt
gaacagccccagaccagttccacgccgcctcgagacttagattccaaagcttgcatttct
atcggaaaccagaactttgaggtgaaggcagatgacctggaaccgatcatggagctgggc
cgaggcgcgtacggagtggtggagaagatgagacatgtgcccagcgggcagatcatggct
gtgaagcggatccgggccaccgtgaacagccaggagcagaaaaggctactgatggacctg
gatgtctccatgaggacagtggactgtcccttcacagtcaccttttacggcgcgctcttc
cgggagggtgatgtttggatctgcatggagctcatggatacatcgctagataaattctac
aaacaagtgattgataaaggccaaaccattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcattagagcatttacacagtaagctctccgtcatccatcgagacgtc
aagccttccaacgtgctgatcaatgctctgggccaggtgaagatgtgcgactttggcatc
agtggctaccttgtagactcggtggctaaaactatcgatgcaggatgcaaaccgtacatg
gctcctgaaaggataaacccggagctcaaccagaagggctacagtgtgaagtctgacatt
tggagtctgggcatcaccatgattgagttggctatcctccggtttccctacgactcctgg
ggaactcctttccagcagctcaaacaggtggtggaggagccgtcaccgcagctgcccgca
gacaagttctccgaagagtttgtggactttacctcgcagtgcttgaagaagaattccaaa
gaacggccaacatatccagagcttatgcaacatccgtttttcactctacacgaatccaaa
gcaacagacgtggcatcttttgtgaaatcgattcttggagactaa

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