Pipistrellus kuhlii (Kuhl's pipistrelle): 118704316
Help
Entry
118704316 CDS
T07682
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
pkl
Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl01521
EGFR tyrosine kinase inhibitor resistance
pkl01522
Endocrine resistance
pkl04010
MAPK signaling pathway
pkl04014
Ras signaling pathway
pkl04015
Rap1 signaling pathway
pkl04066
HIF-1 signaling pathway
pkl04068
FoxO signaling pathway
pkl04081
Hormone signaling
pkl04114
Oocyte meiosis
pkl04140
Autophagy - animal
pkl04144
Endocytosis
pkl04150
mTOR signaling pathway
pkl04151
PI3K-Akt signaling pathway
pkl04152
AMPK signaling pathway
pkl04211
Longevity regulating pathway
pkl04213
Longevity regulating pathway - multiple species
pkl04510
Focal adhesion
pkl04520
Adherens junction
pkl04550
Signaling pathways regulating pluripotency of stem cells
pkl04730
Long-term depression
pkl04913
Ovarian steroidogenesis
pkl04914
Progesterone-mediated oocyte maturation
pkl05200
Pathways in cancer
pkl05202
Transcriptional misregulation in cancer
pkl05205
Proteoglycans in cancer
pkl05214
Glioma
pkl05215
Prostate cancer
pkl05218
Melanoma
pkl05224
Breast cancer
pkl05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
pkl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118704316 (IGF1R)
04014 Ras signaling pathway
118704316 (IGF1R)
04015 Rap1 signaling pathway
118704316 (IGF1R)
04066 HIF-1 signaling pathway
118704316 (IGF1R)
04068 FoxO signaling pathway
118704316 (IGF1R)
04151 PI3K-Akt signaling pathway
118704316 (IGF1R)
04152 AMPK signaling pathway
118704316 (IGF1R)
04150 mTOR signaling pathway
118704316 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
118704316 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
118704316 (IGF1R)
04140 Autophagy - animal
118704316 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
118704316 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
118704316 (IGF1R)
04520 Adherens junction
118704316 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
118704316 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
118704316 (IGF1R)
04914 Progesterone-mediated oocyte maturation
118704316 (IGF1R)
09156 Nervous system
04730 Long-term depression
118704316 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
118704316 (IGF1R)
04213 Longevity regulating pathway - multiple species
118704316 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118704316 (IGF1R)
05202 Transcriptional misregulation in cancer
118704316 (IGF1R)
05205 Proteoglycans in cancer
118704316 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
118704316 (IGF1R)
05214 Glioma
118704316 (IGF1R)
05218 Melanoma
118704316 (IGF1R)
05215 Prostate cancer
118704316 (IGF1R)
05224 Breast cancer
118704316 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
118704316 (IGF1R)
01522 Endocrine resistance
118704316 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pkl01001
]
118704316 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pkl04090
]
118704316 (IGF1R)
Enzymes [BR:
pkl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
118704316 (IGF1R)
Protein kinases [BR:
pkl01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
118704316 (IGF1R)
CD molecules [BR:
pkl04090
]
Proteins
118704316 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Insulin_TMD
Kinase-like
B2
Motif
Other DBs
NCBI-GeneID:
118704316
NCBI-ProteinID:
XP_036267707
LinkDB
All DBs
Position
Unknown
AA seq
1374 aa
AA seq
DB search
MKPALGGGSLASLWALLFVAAVLAVWPTSGEICGPGIDIRNDFRQLKRLENCTVIEGYLH
ILLISKGDDYRSYRFPKLTVITEYLLLFRVAGLESIGDLFPNLTVIRGWKLFYNYALVVF
EMASLKDLGLRNLRNITRGAVRIEKNADLCYVSTVDWSLVLDSVSNNYVAGNKNPKECGD
VCPGALEGTSTCNRTSINNEYKYRCWTQDHCQKTCPSACGKRACTDNHECCHEECLGGCT
APDDQAACVACKHYYHEGVCVAECPPDTYRFEGWRCVDREFCANIPLGDEEDLEEGFELE
GFVLHDGECMQECPSGFIRNDSLSMFCVPCEGPCPKICEEYKGTKTIDSVTSAQMLQGCT
IFKGNLLINIRRGNNIASELENFMGLIEVVTGYIKIRHSHALVSLSFFKSLRQVLGEEQL
EGNYSFYVLDNQNLQQLWDWDTHNLTLKSGKMYFAFNPKLCVSEIYRMEEMTGARGRQGK
GDINTRNNGDRASCESDLLHFTSTNTWKNRIIVTWHRYRPPDYRDLISFTVYYKEAPYQN
VTEYDGQDACGSNSWNMVDVDLPANKDMEPGILLHGLKPWTQYAIYVKAVTLTVVESDHI
RGAKSDILYLRTNASVPSIPLDVISASNSSSQLIVRWNPPSLPNGNLSYYIVRWQQQPQD
AYLYQHNYCSKDKLPVRKYTEGTFDLEEELSENHKSESCKPPKGPCCACPKTEAEKQLEK
EEAEYRKVFENFLHNSIFVPRPDRKRRDLGQVSNTSFSGRGRNSSVTDPFNTTEWVIDDD
SGWEHPFFESRVDKKERTVISNLKPFTLYRIDIHSCNHEADTLGCSASNFVFARTMPAEG
ADDIPGPITWEQKADSVILMWPEPENPNGLILMYEVKYGSQEEDQRECVSRQDYQKYGGA
KLQKLTPGNYTARIQATSLSGNGSWTEPIFFFVQDKALDNHAHLVIALPIAIVLIVFGLA
VTLYVIHRKRNRMGNGVLYASVNPEYFSAADVYVPDEWEVARDKITMNRELGQGSFGMVY
EGVAKGVVKDEPETRVAIKTVNEAATMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQP
TLVIMELMPRGDLKSYLRSLRPEIEPLPVLSPPTLSKMIQMAGEIADGMAYLNANKFVHR
DLAARNCMVAEDLTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSD
VWSFGVVLWEIATLAEQPYQGLSNEQVLHFVMEGGLLDKPDNCPDMLFELMQVCWHFNPK
MRPSFLDIIGSIKDELEPGFIEVSFYYSDENKPPDTEELDLDPSMLECVPLDPSASCASL
PLPERHCQHPVPDGLGQRVLIYHRSSLDDRQAYAQMNGGRKNERPVPLPQSSTC
NT seq
4125 nt
NT seq
+upstream
nt +downstream
nt
atgaagcccgccctcggagggggctccctggcctcgctgtgggcgctcctgttcgtcgcc
gccgtgctcgccgtctggccgacgagcggagaaatctgcggcccgggcatcgacatccgc
aatgacttccggcagctgaagcgcctggagaactgcacggtgatcgagggctacctgcac
atcctgctcatctccaagggcgacgactaccgcagctaccgcttccccaagctcaccgtc
atcaccgagtacctgctgctgttccgcgtggccggcctggagagcatcggcgacctgttc
cccaacctcaccgtcatccgcggctggaagctcttctacaactacgcgctggtggtcttc
gagatggccagcctcaaggacctgggcctgcgcaacctgcgcaacatcacgcgcggcgcc
gtgcgcatcgagaagaacgccgacctgtgctacgtctccaccgtggactggtccctcgtc
ctcgactccgtgtccaacaactacgtggccggcaacaagaaccccaaggagtgcggggac
gtgtgccccggcgccctcgagggcacctccacctgcaaccgcacctccatcaacaacgag
tacaagtaccgctgctggacccaggaccactgccagaaaacctgcccgagcgcgtgcggg
aagcgggcgtgcacggacaaccatgagtgctgccacgaggagtgcctgggcggctgcacg
gccccggacgaccaggcggcctgcgtggcctgcaagcactactaccacgagggcgtgtgc
gtggccgagtgcccgccggacacctaccgcttcgagggctggcgctgcgtggaccgcgag
ttctgcgccaacatccccctcggcgacgaagaggacctggaggagggcttcgagctggag
ggcttcgtcctgcacgacggggagtgcatgcaggagtgcccgtccggcttcatccgcaac
gacagcctgagcatgttctgcgtcccctgcgaagggccgtgccccaagatctgcgaggag
tacaagggcaccaagactatcgactcggtgacctcggctcagatgctccagggctgcacc
atcttcaagggcaacctgctcatcaacatccgcaggggcaataacatcgcctcggaactg
gagaacttcatggggctcatcgaggtggtcacgggctacatcaagatccgccactcccac
gcgctggtctccctgtccttcttcaaaagcctccgccaggtcctgggagaggagcagctg
gaggggaactactccttctacgtcctggacaaccagaacctgcagcagctgtgggactgg
gacacccacaacctgaccctcaagtccggcaagatgtacttcgccttcaaccccaagctg
tgcgtgtccgagatctaccgcatggaggagatgaccggggcccgggggcgccagggcaag
ggcgacatcaacacccgcaacaacggcgacagggcctcctgtgaaagcgacctgctgcac
ttcacgtccaccaacacctggaagaaccgcatcatcgtcacgtggcaccggtaccgcccc
ccagactacagggacctcatcagcttcaccgtctactacaaggaggcgccctaccagaac
gtgaccgagtacgacggccaggacgcctgcggctccaacagctggaacatggtggacgtg
gacctgcccgccaacaaggacatggagcccggcatcctcctgcacggcctcaagccctgg
acgcagtacgccatctacgtgaaggccgtgaccctgaccgtggtggagagcgaccacatc
cgcggggccaagagcgacatcctgtacctccgcaccaacgcctcagtgccttccatcccg
ctggacgtcatctcggcctccaactcgtcctcccagctgatcgtcaggtggaacccgccc
tcgctgcccaacgggaacctgagctactacatcgtgcgctggcagcagcagccgcaggac
gcctacctgtaccagcacaactactgctccaaagacaagctcccggtgcggaagtacacg
gaaggcaccttcgacctggaggaggagctgtcggagaaccacaagtccgagtcctgcaaa
ccccccaaggggccctgctgcgcctgccccaaaaccgaggccgagaagcagctggagaag
gaggaggccgagtaccgcaaggtcttcgagaacttcctgcacaactccatcttcgtgccc
cggcccgacaggaagcgccgggacctggggcaggtctccaacaccagcttctccggccgg
ggccgcaacagctcggtgaccgaccccttcaacaccaccgagtgggtcatcgacgacgac
tcgggctgggagcaccccttcttcgagagccgcgtggacaagaaggagcggaccgtcatc
tccaacctgaagcccttcaccctctaccgcatcgacatccacagctgcaaccacgaggcc
gacacgctgggctgcagtgcctccaacttcgtcttcgcccggaccatgcctgcagaggga
gcagatgacattcccgggcccatcacctgggagcagaaggccgactccgtcatcttaatg
tggccggagcctgagaaccccaacgggctgatcctcatgtatgaggtcaagtacgggtcc
caggaggaggaccagcgggagtgcgtgtcccggcaggactaccagaagtacggaggggcc
aagctgcagaagctcaccccggggaactacacggcccgcatccaggccacctccctgtcc
gggaacgggtcctggacagagcccatcttcttcttcgtccaggacaaagccttggacaat
cacgcccacctggtcatcgccctgcccatcgccatcgtgctgatcgtcttcgggctggcc
gtcacgctgtacgtcatccaccggaagcgcaatcgcatggggaacggagtgctgtacgcg
tctgtgaaccccgagtatttcagcgcggccgacgtgtacgtgcccgacgagtgggaggtg
gcccgggataagatcaccatgaaccgggagctgggccagggctccttcggcatggtgtac
gagggcgtggccaaaggcgtggtcaaggacgagccggaaaccagggtggccatcaagacg
gtcaatgaggcggccaccatgcgggagcggatcgagttcctcaacgaggcctcggtgatg
aaggagttcaactgtcaccatgtggtgcgtttgctgggtgtggtgtcccagggccagccc
accctggtcatcatggagcttatgccccggggtgacctcaagagttacctccggtctctg
cgcccggaaatcgagcccctccccgtcctctcaccgccgaccctcagcaagatgatccag
atggccggggagatcgcggacggcatggcgtacctcaacgccaacaagttcgtccacagg
gacctcgctgcccgcaactgcatggtggctgaggatctgaccgtcaagatcggagatttc
ggcatgacccgcgacatctacgagaccgactactaccggaagggcgggaagggcctgctg
cctgtgcgctggatgtcccccgagtccctcaaggacggcgtgttcaccacccactctgat
gtctggtccttcggtgttgtgctctgggagatcgccacgctggccgagcagccctaccag
ggcctgtccaacgagcaagtcctgcacttcgtcatggagggcggcctgctggacaagccc
gacaactgccccgacatgctgttcgagctgatgcaggtgtgctggcacttcaaccccaag
atgcggccctccttcctggacatcatcggcagcatcaaggacgagctggagcccggcttc
atagaggtgtccttctactacagcgacgagaacaagccgcccgacaccgaggagctcgac
ctggacccctccatgctggagtgcgtgcccctcgacccctcggcctcctgcgcctccctg
ccgctgcccgagcgccactgccagcaccccgtccccgacggcctgggccagcgcgtgctc
atctaccaccgctccagcctcgacgacaggcaggcctacgcccagatgaacggggggcgc
aagaacgagaggcccgtgcctctcccccagtcctccacctgctga
DBGET
integrated database retrieval system
