Pipistrellus kuhlii (Kuhl's pipistrelle): 118704378
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Entry
118704378 CDS
T07682
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
5.6.1.10
]
Organism
pkl
Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl03060
Protein export
pkl04141
Protein processing in endoplasmic reticulum
pkl04612
Antigen processing and presentation
pkl04918
Thyroid hormone synthesis
pkl05012
Parkinson disease
pkl05014
Amyotrophic lateral sclerosis
pkl05020
Prion disease
pkl05022
Pathways of neurodegeneration - multiple diseases
pkl05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pkl00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
118704378 (HSPA5)
04141 Protein processing in endoplasmic reticulum
118704378 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
118704378 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
118704378 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
118704378 (HSPA5)
05014 Amyotrophic lateral sclerosis
118704378 (HSPA5)
05020 Prion disease
118704378 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
118704378 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
118704378 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
pkl03110
]
118704378 (HSPA5)
04131 Membrane trafficking [BR:
pkl04131
]
118704378 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pkl04147
]
118704378 (HSPA5)
Enzymes [BR:
pkl01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.10 non-chaperonin molecular chaperone ATPase
118704378 (HSPA5)
Chaperones and folding catalysts [BR:
pkl03110
]
Heat shock proteins
HSP70 / DNAK
118704378 (HSPA5)
Membrane trafficking [BR:
pkl04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
118704378 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
118704378 (HSPA5)
Exosome [BR:
pkl04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
118704378 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
118704378 (HSPA5)
Exosomal proteins of colorectal cancer cells
118704378 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
FtsA
Hydantoinase_A
FGGY_C
DDR
NPA
ParM_N
Motif
Other DBs
NCBI-GeneID:
118704378
NCBI-ProteinID:
XP_036267879
LinkDB
All DBs
Position
Unknown
AA seq
653 aa
AA seq
DB search
MKLSLVAAVLLLLGAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETVEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGAPPEEEEPADKDEL
NT seq
1962 nt
NT seq
+upstream
nt +downstream
nt
atgaagctctccctggtggctgcggtgctgctgctgctcggcgcggcgcgggccgaggag
gaggacaagaaggaggacgtgggcacggtggtcggcatcgacctggggaccacctactcc
tgcgttggggtgtttaagaacggccgcgtggagatcatcgccaacgatcagggcaaccgc
atcaccccgtcttatgtggccttcacgcccgaaggggagcgtctgatcggcgatgccgcc
aagaaccagctcacctccaaccccgagaacacggtcttcgacgccaagcggctcatcggc
cgcacatggaacgacccgtctgtgcagcaggacatcaagttcttgcctttcaaggtggtt
gaaaagaaaactaaaccatacattcaagttgatattggaggcgggcaaacaaagactttt
gctcctgaagaaatatctgccatggttctcactaaaatgaaggaaactgctgaggcttat
ttgggaaagaaggttactcatgcagttgttactgtaccagcctatttcaatgatgcccaa
cgccaggcaaccaaagatgctgggactattgctggattgaatgtcatgaggatcatcaat
gagcctacagcagctgctatcgcctatggcctagataagagggaaggggagaagaacatt
ctggtgtttgacctgggtggtggaaccttcgacgtgtcccttctcaccattgataatggt
gtcttcgaagttgtggccactaatggggacactcacctgggtggagaagattttgaccag
cgtgtcatggaacacttcatcaagctctacaaaaagaagactggcaaagatgtcaggaaa
gacaacagagctgtgcagaaactccgccgtgaggtcgaaaaggccaagcgggccctgtct
tctcaacaccaagcaagaattgaaattgagtccttcttcgaaggagaagacttctctgag
accctgactcgggccaagtttgaagagctgaacatggacctgttccgctctaccatgaag
cctgtccagaaagtgctggaggattctgatttgaagaagtctgatattgatgaaattgtc
cttgttggtggctctactcgaatcccaaagattcaacagctggttaaagagttcttcaat
ggcaaggagccatcccgtggcataaacccagatgaggctgtcgcgtatggtgctgctgtc
caggctggtgtactctctggtgatcaagatacaggtgatctggtactgcttgacgtgtgt
ccccttacgcttggtattgaaactgtgggaggtgtcatgactaaactgattccaaggaac
actgtggtgcccaccaagaagtcacagatcttttctacagcctctgataatcagccaact
gttacaatcaaggtttatgaaggtgaacgtcccctgacaaaagacaaccatctcctggga
actttcgatctgaccggaattcctcctgctcctcgtggggtcccgcagattgaggtcacc
tttgagatagatgtgaatggcattctccgagtgacagccgaagacaaaggtacaggcaac
aaaaacaagatcacaattaccaatgatcagaatcgcctgacacctgaagaaattgaaagg
atggttaacgatgcagagaagtttgctgaggaggacaaaaagctcaaggagcgcattgat
accagaaatgaattggaaagttacgcctattctctaaagaatcaaattggagataaagaa
aagctgggagggaaactttcctctgaagataaggagaccgtggaaaaagctgtagaggaa
aagattgaatggctggaaagtcaccaagatgctgacattgaagatttcaaagctaaaaag
aaggaactagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggcgcc
ccacctgaggaagaggaaccagcagacaaggatgagttgtag
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