Pipistrellus kuhlii (Kuhl's pipistrelle): 118704763
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Entry
118704763 CDS
T07682
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
pkl
Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl00220
Arginine biosynthesis
pkl00330
Arginine and proline metabolism
pkl01100
Metabolic pathways
pkl04020
Calcium signaling pathway
pkl04022
cGMP-PKG signaling pathway
pkl04066
HIF-1 signaling pathway
pkl04071
Sphingolipid signaling pathway
pkl04151
PI3K-Akt signaling pathway
pkl04370
VEGF signaling pathway
pkl04371
Apelin signaling pathway
pkl04611
Platelet activation
pkl04915
Estrogen signaling pathway
pkl04921
Oxytocin signaling pathway
pkl04926
Relaxin signaling pathway
pkl04931
Insulin resistance
pkl04933
AGE-RAGE signaling pathway in diabetic complications
pkl05415
Diabetic cardiomyopathy
pkl05417
Lipid and atherosclerosis
pkl05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pkl00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
118704763 (NOS3)
00330 Arginine and proline metabolism
118704763 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
118704763 (NOS3)
04371 Apelin signaling pathway
118704763 (NOS3)
04066 HIF-1 signaling pathway
118704763 (NOS3)
04020 Calcium signaling pathway
118704763 (NOS3)
04071 Sphingolipid signaling pathway
118704763 (NOS3)
04022 cGMP-PKG signaling pathway
118704763 (NOS3)
04151 PI3K-Akt signaling pathway
118704763 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
118704763 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
118704763 (NOS3)
04921 Oxytocin signaling pathway
118704763 (NOS3)
04926 Relaxin signaling pathway
118704763 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
118704763 (NOS3)
05418 Fluid shear stress and atherosclerosis
118704763 (NOS3)
05415 Diabetic cardiomyopathy
118704763 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
118704763 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
118704763 (NOS3)
Enzymes [BR:
pkl01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
118704763 (NOS3)
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Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
HTH_15
Motif
Other DBs
NCBI-GeneID:
118704763
NCBI-ProteinID:
XP_036268545
LinkDB
All DBs
Position
Unknown
AA seq
1201 aa
AA seq
DB search
MGNLKSVGQEPGPHCGLGLGLGLSLCGKQGPASPAAPEPSKPPAPVPQTAPDPSPPLTRP
PEGPRFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQSRPAQGSPPTEQ
LLSQARDFITQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAP
RCVGRIQWGKLQVFDARDCSSAQEMFTYICSHIKYATNRGNLRSAITVFPQRAPGRGDFR
IWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPEL
FTVPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEI
GTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDHHA
ATSSFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWKG
SGAKGAGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLF
RKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAEALMEMSGPYNSSPR
PEQHKSYKMRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCA
FARAVDTRLEELGGERLLPLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAAARD
IFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMLQATVLSVENLQSSKSTRATILVR
LDTGGQEGFQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPPGEPVAVEQLEKGSPGGPPP
GWVRDPRLPPCTLRQALTFFLDITSPPSPRLLRLLSTLAEEPGEQQELETLSQDPRRYEE
WKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHPREIHLTVAVLAY
RTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFR
GFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYREEVQDAQQRGVFGRVLTAFSREPD
SPKTYVQDILRTELAAEVHRVLCIERGHMFVCGDVTMATSVLQTVQRILAAEGDMELDEA
GDVIGELRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHQRSAVPWAFDPPGPDTPC
P
NT seq
3606 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagcgtgggccaggagcccgggccacactgcggcctgggactgggg
ctgggcctcagcctgtgcggcaagcaaggcccggcctcgcctgcagccccggagcccagc
aagccgccagcacccgtaccccagaccgcgccggaccccagcccccccctgacccggccc
ccggaggggcccaggtttcctcgtgtgaagaactgggaggtggggagcatcacctatgac
accctgagcgcccaggcacagcaggacgggccctgcaccccacgccgctgcctgggctcc
ctggtgtttccacggaaactgcagagccggcccgcccagggctccccacccacagagcag
ctgctgagccaggccagggacttcatcacccagtattacagctccatcaagaggagcggc
tcccaggcccacgagcagcgtctccaggaggtggaagccgaggtggcggccacgggcacc
taccagctccgggagagcgagctggtgttcggggccaagcaggcctggcgcaacgcccca
cgctgcgtgggccggatccagtggggcaagctgcaggtgttcgacgcccgggactgcagc
tccgcgcaggagatgttcacctacatctgcagccacatcaagtacgccaccaaccggggc
aacctccgctcggccatcaccgtgttcccccagcgcgccccgggccggggagacttccgg
atctggaacagccagctggtgcgctacgccggctacaggcagcaggacggctccgtgcga
ggggacccggccaacgtggagatcaccgagctctgcatccagcacggctggacccccggc
aacggccgcttcgacgtgctgcccctgctgctccaggccccagatgagcccccagaactc
ttcactgtgccccccgagctagtcctcgaggtgccactggagcaccccacgctggagtgg
ttcgcggccctgggcctgcgctggtacgccctcccggccgtgtccaacatgttgctggag
atcgggggcctggagttccccgccgcccccttcagcggctggtacatgagcacagagatc
ggcacgcggaacctgtgcgaccctcaccgctacaacatcctggaggatgtggctgtctgc
atggacctggacacccggaccacctcgtccctgtggaaagacaaggcggccgtggagatc
aacttggccgtgctgcacagctaccagctggccaaggtgaccatcgtggaccaccacgcc
gccacctcctccttcatgaagcacctggagaatgagcagaaggccagagggggctgccct
gccgactgggcctggatcgtgccccccatctcgggcagcctcacccctgtcttccatcaa
gagatggtcaactatttcctgtcccccgccttccgctaccagccggatccctggaagggc
agtggagccaagggcgccggcatcaccaggaagaagaccttcaaggaagtggccaatgcg
gtgaagatctccgcctcactcatgggcacggtcatggccaagcgtgtgaaggcgacgatc
ctgtacggctccgagaccggccgggcccagagctacgcgcagcagctggggagactcttc
cggaaggctttcgacccccgggtcctgtgcatggacgagtatgacgtggtgtccctggag
cacgagacgctggtgttggtggtgaccagcacgtttgggaacggggatcccccagagaac
ggagagagtttcgcagaggccctgatggagatgtcgggcccctacaacagctccccgcgg
cccgaacagcacaagagttacaaaatgcgcttcaacagcgtctcctgctcagacccgctg
gtgtcctcctggcggcggaagaggaaggagtccagcaacacggacagcgcgggggccctg
gggaccctcaggttctgtgtgttcggcctgggctcgcgggcgtacccccacttctgcgcc
tttgcccgcgcggtggacacgcggctggaggagctgggcggggagcggctcctgcctctg
ggccagggcgacgagctgtgtggccaggaggaggcgttccgcggctgggcccaggccgcc
ttccaggcctcctgcgagaccttctgcgtgggagaagacgccaaggccgccgcccgggac
atattcagccccaagcggagctggaagcgccagcgctaccggctcagcgcccaggccgag
ggcctccaactgctgccaggcctgatccatgtgcacaggaggaagatgctccaggccaca
gtcctctcagtggaaaacctgcagagcagcaagtccacccgggccacgatcctggtgcgc
ctggacaccggaggccaggaggggttccagtaccagcccggggaccacatcggcgtctgc
ccgcccaaccggcccggcctggtggaggccctgctgagccgcgtggaggacccgccgccc
cccggcgagccggtggccgtggagcagctggagaagggcagccctggtggccctcccccc
ggctgggtgcgggacccccggctgcccccctgcacgctgcgccaggccctcaccttcttc
ctggacatcacctccccgcccagccctcgcctcctgcgactgctcagcaccctggccgag
gagcccggcgaacagcaggagctcgagaccctcagccaggacccccggcgctacgaggag
tggaagtggttccgctgccccacgctcctggaggtgctggagcagttcccgtcggtggcg
ctgcccgcccccctgctcctcacccagctgcccctgctccagccccggtactattccgtc
agctccgcgcccagcgcccacccgcgggagatccacctcaccgtggccgtgctggcatac
aggacccaggacgggctgggtcccctgcactacggtgtctgctccacgtggctcagccag
ctcaaggccggagaccccgtgccctgcttcatccggggggctccgtccttccggctgcca
cccgaccccagcctgccctgcatcctggtgggcccaggcaccggcatcgcccccttccgg
ggattctggcaggagcggctgcacgacattgagagcaaagggctgcagcccgcccccatg
accttggtgtttggctgccggtgctcccagctggaccacctctaccgcgaggaggtgcag
gacgcccagcagcgcggggtgttcggccgcgttctcaccgctttctcccgcgaacccgac
agccctaagacctacgtgcaggacatccttcggacggagctggctgcggaggtgcaccga
gtgctgtgcatcgagcggggccacatgtttgtctgcggcgacgtcaccatggcaaccagc
gtcctgcaaacggtgcagcgcatcctggcggcagagggcgacatggagctggacgaggcg
ggcgacgtcatcggcgagctgcgggatcagcaacgctaccacgaggacattttcgggctc
acactgcgcacccaggaggtgaccagccgcatacgcacccagagtttctccttgcaggag
cggcaccagcggagcgcagtgccctgggctttcgacccgcccggcccagacaccccgtgc
ccctga
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integrated database retrieval system
