Pipistrellus kuhlii (Kuhl's pipistrelle): 118706676
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Entry
118706676 CDS
T07682
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
pkl
Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl00790
Folate biosynthesis
pkl01100
Metabolic pathways
pkl01240
Biosynthesis of cofactors
pkl01523
Antifolate resistance
pkl04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
pkl00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
118706676 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
118706676 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
118706676 (FPGS)
Enzymes [BR:
pkl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
118706676 (FPGS)
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Paralog
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
118706676
NCBI-ProteinID:
XP_036272074
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All DBs
Position
Unknown
AA seq
589 aa
AA seq
DB search
MSRARSRLRASLRLAAAFPRGVTTGVTGAREFSARPAPQEPGMEYQDAVRTLNTLQTNAS
YLEQVKRQRGDPQAQLEAMKLFLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFRCPGSSPHLVQVRERIRINGQPISPEHFTKYFWRLYHRLEETKDSSSCVSMP
AYFRFLTLMAFHVFLQEKVDLAVMEVGIGGAYDCTNIVRKPVVCGVSALGMDHTSLLGDT
MEKIAWQKGGIFKRGVPAFTVPQPDGPLAVLRERAEQVSCPLYLCPPLDALEDGAPPLTL
GLEGEHQRSNAALALQLARCWLQRKDRHGIGELRVSRPSLLCQLPLAPVFQPTAPMRHGL
RDTEWPGRTQMLCRGPLTWYLDGAHTCSSVQACVRWFRQALQRRKGGPEVRVLLFNSTGD
RDPAALLKLLQPCQFDYAVFCPNLTEVSSVGNADQQNFMVTLDQVLLRCLEHQQHWSRLQ
EAAAGPDLWSAPSPEAGGPASLLLAPRLPHPRGASSLVFSCISHALQWISQGRDPVLQTP
SPPRDLLSHPVASSGASVLREAAAVHVLVTGSLHLVGGVLKLLDPSLSQ
NT seq
1770 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcacgcagccgcctgcgcgcaagtctccgcctggcagcggctttcccgcgc
ggcgtaacgaccggggtcacgggagcgcgagagtttagcgcgcggcccgcgccgcaggag
cccggcatggaataccaggatgccgtgcgcacactcaacaccctgcagaccaacgccagc
tacctggagcaggtaaagcgccagcggggcgacccccaggcccagctggaagccatgaag
ctgttcctggcgcggagcgggctgcaggtggaggacttggaccagctgaacatcatccac
gtgactgggacgaaggggaagggctccacctgtgccttcacggagcgcatcctccggagc
tacggcctgaagacggggttcttcaggtgtcccggcagctctccccacctggtgcaggtg
cgcgagcggatccgcatcaacgggcagcccatcagccccgagcacttcaccaagtacttc
tggcgcctctaccacaggctggaggagaccaaggacagcagcagctgtgtctccatgcct
gcatacttccgcttcctcacgctcatggccttccacgtcttcctgcaagagaaggtggac
ctggcagtgatggaagtgggtattggcggggcttatgactgcaccaacatagtcaggaag
cctgtggtgtgtggggtctccgctcttggcatggaccacacgagcctcctgggggacacg
atggagaagatcgcgtggcagaaagggggcatcttcaagcgtggcgtccccgccttcact
gtgccccagcctgacgggcccctggcggtgctgagggagcgcgccgagcaggtctcgtgt
cccctctacctgtgtccaccgctggacgccctggaggacggggcccccccgctgaccctg
ggcctggagggagagcaccagcggtccaatgccgccttggccctgcagctggcccgctgc
tggctgcagcggaaggaccgccacggcattggggagctgagagtgtccaggccgagcctc
ctgtgtcagctgcctctggcccccgtgttccagcccacggcccccatgcggcatgggctt
cgggacacggagtggcctggccggacgcagatgctgtgccgcgggcccctcacctggtac
ctggacggcgcgcacacctgcagcagcgtgcaggcctgcgtgcgctggttccgccaggcg
ctgcagcgccgcaagggtgggcccgaggtgcgcgtcctgctcttcaactccacgggtgac
cgggacccggcggccctgctgaagctgctgcagccctgccagttcgactacgctgtcttc
tgccccaacctgacagaggtgtcatccgtgggcaacgcagaccagcagaacttcatggtg
accctggaccaggtgctgctccgctgcttggagcaccagcagcactggagccgcctgcag
gaggcggcggccggcccggacctctggagcgcccccagcccggaggctggggggccggcc
tccctgctgctggcaccccgcctgccccacccccgcggcgccagctccctcgtcttcagc
tgcatctcccatgctctgcagtggatcagccagggccgggaccctgtcctccagaccccc
agcccccctcgggacctcctctcccaccctgtggccagcagcggggccagcgtgctccga
gaggccgccgccgtccatgtgctggtcacgggaagcctgcacctggtgggcggcgtgctg
aagctgctggacccctccctgtcccagtag
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