Pipistrellus kuhlii (Kuhl's pipistrelle): 118707729
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Entry
118707729 CDS
T07682
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
pkl
Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl04022
cGMP-PKG signaling pathway
pkl04024
cAMP signaling pathway
pkl04062
Chemokine signaling pathway
pkl04071
Sphingolipid signaling pathway
pkl04270
Vascular smooth muscle contraction
pkl04350
TGF-beta signaling pathway
pkl04360
Axon guidance
pkl04510
Focal adhesion
pkl04520
Adherens junction
pkl04530
Tight junction
pkl04611
Platelet activation
pkl04670
Leukocyte transendothelial migration
pkl04810
Regulation of actin cytoskeleton
pkl04921
Oxytocin signaling pathway
pkl05135
Yersinia infection
pkl05163
Human cytomegalovirus infection
pkl05200
Pathways in cancer
pkl05205
Proteoglycans in cancer
pkl05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
pkl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
118707729 (ROCK1)
04071 Sphingolipid signaling pathway
118707729 (ROCK1)
04024 cAMP signaling pathway
118707729 (ROCK1)
04022 cGMP-PKG signaling pathway
118707729 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
118707729 (ROCK1)
04520 Adherens junction
118707729 (ROCK1)
04530 Tight junction
118707729 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
118707729 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
118707729 (ROCK1)
04670 Leukocyte transendothelial migration
118707729 (ROCK1)
04062 Chemokine signaling pathway
118707729 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
118707729 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
118707729 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
118707729 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118707729 (ROCK1)
05206 MicroRNAs in cancer
118707729 (ROCK1)
05205 Proteoglycans in cancer
118707729 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
118707729 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
118707729 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pkl01001
]
118707729 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pkl03036
]
118707729 (ROCK1)
Enzymes [BR:
pkl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
118707729 (ROCK1)
Protein kinases [BR:
pkl01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
118707729 (ROCK1)
Chromosome and associated proteins [BR:
pkl03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
118707729 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Cortex-I_coil
Pkinase_C
APH
Motif
Other DBs
NCBI-GeneID:
118707729
NCBI-ProteinID:
XP_036274372
LinkDB
All DBs
Position
Unknown
AA seq
1354 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRTSSNV
DKSLQETLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKIDKIMKELDEEGNQRRNLEST
VSQIEKEKMMLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL
AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTD
KEYYQLQAALEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNVERVEEERKDAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMYEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTESKERMEDEVKNLTLQLEQES
NKRLFFQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEMNSMLTKDVELLRKENE
ELTDKMRKSEEDFKQKKEEEINNLKAAFEKNISTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASLPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS
NT seq
4065 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattctgattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaatcagagatttacgaatgaaagctgaagactatgaagtagtgaag
gtgattggtagaggtgcgtttggagaagttcaattggtaaggcataaatccaccaggaag
gtatatgctatgaagcttctcagcaaatttgaaatgattaagagatccgattctgctttt
ttctgggaagaaagggacatcatggcttttgctaatagcccttgggttgttcagcttttt
tatgcattccaagatgatcgttatctctacatggtgatggaatatatgcctggtggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcacgattctatactgca
gaagtagttcttgcattggatgcaatccattccatgggttttattcatagagatgtgaag
cctgataacatgctgctggataaatctggacatttgaagttagctgattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgacacggcagttggaacacctgattat
atttcccctgaagtattaaagtctcaaggtggtgatggttattatggacgagaatgtgac
tggtggtcagttggagtatttttgtatgaaatgcttgtaggtgatacacctttttatgca
gattctctggttggaacttacagtaagattatgaaccataaaaattcacttaccttccct
gatgataatgacatatcaaaagaagcaaaaaatcttatttgcgcctttcttactgataga
gaggtgagattagggcgaaatggtgtcgaagaaatcaaacgacatctcttcttcaaaaat
gatcagtgggcttgggaaacacttcgagacactgtagcaccagttgtacctgatttaagt
agtgatattgatacaagtaactttgatgacttggaagaagataaaggagatgaggaaaca
ttccctatacctaaagcttttgttggcaatcaactaccttttgtaggatttacatattac
agcaatcgtagatacttatcttcagcaaatcctaatgataacagaactagctccaatgtg
gataaaagcttgcaggaaactttgcaaaaaacaatttacaagctggaagaacaactgcat
aatgagatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaacattaaaata
gacaaaataatgaaagaattggatgaagaggggaatcaaagaagaaatctagaatctaca
gtgtctcagattgagaaagagaaaatgatgctacagcatagaattaatgaataccaaaga
aaagcagaacaggaaaatgaaaagaggagaaatgtagaaaatgaagtttctacattaaag
gatcagttggaagacttaaagaaagtaagtcagaattcacagcttgctaatgagaagctg
gcacaattacaaaagcagctggaagaagccaatgatttacttaggacagaatcagacaca
gctgtaagattaaggaaaagtcacacagagatgagcaagtcaattagtcaactagagtcc
ctgaacagagaattgcaggagagaaatagaattctagagaattccaagtcacaaacagat
aaggagtattaccagctgcaagctgcattggaagctgaacgaagagacagaggacatgat
tctgagatgattggagaccttcaagctcgaattacatctttacaagaggaggtgaagcat
ctcaaacataatgttgaaagagtagaagaagaaagaaaagatgctcaagacatgcttaat
cattcagaaaaggaaaagaataatttagagatagatttaaactataagctgaaatcctta
caacaacggttagaacaagaggtaaatgaacataaagtaaccaaagctcgtttaactgac
aaacatcagtctattgaagaggcaaaatctgttgcaatgtatgagatggaaaaaaagctg
aaggaagagagagaagctcgagaaaaggctgaaaatagggttgttcagattgagaaacag
tgttccatgctagatgttgatctgaaacaatctcagcagaagcttgaacatttgactgaa
agtaaagaaagaatggaggatgaagttaagaatcttactctgcaattggagcaggaatca
aataagcgactcttctttcaaaatgaattgaagactcaagcatttgaggcagacaattta
aaaggtctagaaaagcagatgaaacaggaaataaatactttactggaagcaaagagatta
ttagaatttgaattagctcaacttacaaaacaatatagaggaaatgaaggacagatgcgg
gaactacaagatcaacttgaagctgaacaatatttctcgacactttataaaacccaggta
aaggaactgaaggaagaaattgaagaaaaaaacagagaaaatttaaaaaaaatacaggaa
ctacaaaatgagaaagaaactcttgctactcagctggatctagcggaaacaaaagctgag
tctgagcagttggctcgagggcttttagaagaacagtactttgaattgacccaagaaagc
aagaaagctgcttcaagaaacagacaagagattacagataaagatcacactgttagtcgg
cttgaggaaatgaacagtatgctaaccaaagatgttgaattattaagaaaagaaaatgaa
gagctaactgataaaatgaggaaatcagaggaagatttcaaacagaagaaagaggaggag
atcaataatcttaaggctgcctttgaaaagaatatcagtacagaacgaactcttaaaaca
caggctgttaacaagttggcagaaataatgaatcgaaaagactttaaaattgatagaaag
aaagctaatacacaggatttgaggaagaaagaaaaggaaaatcgaaagctacaactggaa
ctcaaccaagaaagagagaaattcaaccagatggtagtgaaacatcagaaggaactgaat
gacatgcaagcgcaattggtagaagaatgtacacataggaatgagcttcaaatgcagttg
gctagcaaagagagtgatatcgagcaattgcgtgctaaacttctggacctatcggattct
acgagtgttgctagtttgcctagtgctgatgaaactgatggaaaccttccagagtcaaga
attgaaggttggctttcaataccaaatagaggaaatatcaaacgatatggctggaagaaa
cagtatgttgtggtaagcagcaagaaaattttattttataacgatgaacaagataaggaa
caatccaatccatctatggtattagacatagataaattgttccatgttcgacctgtaacc
caaggagatgtgtatagagctgaaactgaagaaattcctaaaatatttcagatactttat
gcaaatgaaggtgaatgtagaaaagatgtagagatggaaccagtacaacaagctgaaaaa
actaattttcagaatcacaaaggccatgagttcattcctacactctaccactttcccgcc
aactgtgaggcctgtgccaaacctctctggcatgtttttaagccaccccctgccctagaa
tgtcgaagatgccatgttaagtgccacagagatcatttagataagaaagaggacctaatt
tctccatgtaaagtaagttatgatgtaacatcagcaagagatatgctgttgttagcatgt
tctcaggatgaacaaaagaaatgggtaactcatttagtgaaaaagatacctaagaatcca
ccatctggttttgttcgtgcatcccctcgaacactttctacaagatccactgcaaatcaa
tctttccggaaagtggttaaaaatacatctggaaaaactagttaa
DBGET
integrated database retrieval system