KEGG   Pipistrellus kuhlii (Kuhl's pipistrelle): 118707729
Entry
118707729         CDS       T07682                                 
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
  KO
K04514  Rho-associated protein kinase 1 [EC:2.7.11.39]
Organism
pkl  Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl04022  cGMP-PKG signaling pathway
pkl04024  cAMP signaling pathway
pkl04062  Chemokine signaling pathway
pkl04071  Sphingolipid signaling pathway
pkl04270  Vascular smooth muscle contraction
pkl04350  TGF-beta signaling pathway
pkl04360  Axon guidance
pkl04510  Focal adhesion
pkl04520  Adherens junction
pkl04530  Tight junction
pkl04611  Platelet activation
pkl04670  Leukocyte transendothelial migration
pkl04810  Regulation of actin cytoskeleton
pkl04921  Oxytocin signaling pathway
pkl05135  Yersinia infection
pkl05163  Human cytomegalovirus infection
pkl05200  Pathways in cancer
pkl05205  Proteoglycans in cancer
pkl05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:pkl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    118707729 (ROCK1)
   04071 Sphingolipid signaling pathway
    118707729 (ROCK1)
   04024 cAMP signaling pathway
    118707729 (ROCK1)
   04022 cGMP-PKG signaling pathway
    118707729 (ROCK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    118707729 (ROCK1)
   04520 Adherens junction
    118707729 (ROCK1)
   04530 Tight junction
    118707729 (ROCK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    118707729 (ROCK1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118707729 (ROCK1)
   04670 Leukocyte transendothelial migration
    118707729 (ROCK1)
   04062 Chemokine signaling pathway
    118707729 (ROCK1)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    118707729 (ROCK1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    118707729 (ROCK1)
  09158 Development and regeneration
   04360 Axon guidance
    118707729 (ROCK1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118707729 (ROCK1)
   05206 MicroRNAs in cancer
    118707729 (ROCK1)
   05205 Proteoglycans in cancer
    118707729 (ROCK1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    118707729 (ROCK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    118707729 (ROCK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pkl01001]
    118707729 (ROCK1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:pkl03036]
    118707729 (ROCK1)
Enzymes [BR:pkl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.39  ROCK-subfamily protein kinase
     118707729 (ROCK1)
Protein kinases [BR:pkl01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   118707729 (ROCK1)
Chromosome and associated proteins [BR:pkl03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    118707729 (ROCK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 Cortex-I_coil Pkinase_C APH
Other DBs
NCBI-GeneID: 118707729
NCBI-ProteinID: XP_036274372
LinkDB
Position
Unknown
AA seq 1354 aa
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRTSSNV
DKSLQETLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKIDKIMKELDEEGNQRRNLEST
VSQIEKEKMMLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL
AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTD
KEYYQLQAALEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNVERVEEERKDAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMYEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTESKERMEDEVKNLTLQLEQES
NKRLFFQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEMNSMLTKDVELLRKENE
ELTDKMRKSEEDFKQKKEEEINNLKAAFEKNISTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASLPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS
NT seq 4065 nt   +upstreamnt  +downstreamnt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattctgattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaatcagagatttacgaatgaaagctgaagactatgaagtagtgaag
gtgattggtagaggtgcgtttggagaagttcaattggtaaggcataaatccaccaggaag
gtatatgctatgaagcttctcagcaaatttgaaatgattaagagatccgattctgctttt
ttctgggaagaaagggacatcatggcttttgctaatagcccttgggttgttcagcttttt
tatgcattccaagatgatcgttatctctacatggtgatggaatatatgcctggtggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcacgattctatactgca
gaagtagttcttgcattggatgcaatccattccatgggttttattcatagagatgtgaag
cctgataacatgctgctggataaatctggacatttgaagttagctgattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgacacggcagttggaacacctgattat
atttcccctgaagtattaaagtctcaaggtggtgatggttattatggacgagaatgtgac
tggtggtcagttggagtatttttgtatgaaatgcttgtaggtgatacacctttttatgca
gattctctggttggaacttacagtaagattatgaaccataaaaattcacttaccttccct
gatgataatgacatatcaaaagaagcaaaaaatcttatttgcgcctttcttactgataga
gaggtgagattagggcgaaatggtgtcgaagaaatcaaacgacatctcttcttcaaaaat
gatcagtgggcttgggaaacacttcgagacactgtagcaccagttgtacctgatttaagt
agtgatattgatacaagtaactttgatgacttggaagaagataaaggagatgaggaaaca
ttccctatacctaaagcttttgttggcaatcaactaccttttgtaggatttacatattac
agcaatcgtagatacttatcttcagcaaatcctaatgataacagaactagctccaatgtg
gataaaagcttgcaggaaactttgcaaaaaacaatttacaagctggaagaacaactgcat
aatgagatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaacattaaaata
gacaaaataatgaaagaattggatgaagaggggaatcaaagaagaaatctagaatctaca
gtgtctcagattgagaaagagaaaatgatgctacagcatagaattaatgaataccaaaga
aaagcagaacaggaaaatgaaaagaggagaaatgtagaaaatgaagtttctacattaaag
gatcagttggaagacttaaagaaagtaagtcagaattcacagcttgctaatgagaagctg
gcacaattacaaaagcagctggaagaagccaatgatttacttaggacagaatcagacaca
gctgtaagattaaggaaaagtcacacagagatgagcaagtcaattagtcaactagagtcc
ctgaacagagaattgcaggagagaaatagaattctagagaattccaagtcacaaacagat
aaggagtattaccagctgcaagctgcattggaagctgaacgaagagacagaggacatgat
tctgagatgattggagaccttcaagctcgaattacatctttacaagaggaggtgaagcat
ctcaaacataatgttgaaagagtagaagaagaaagaaaagatgctcaagacatgcttaat
cattcagaaaaggaaaagaataatttagagatagatttaaactataagctgaaatcctta
caacaacggttagaacaagaggtaaatgaacataaagtaaccaaagctcgtttaactgac
aaacatcagtctattgaagaggcaaaatctgttgcaatgtatgagatggaaaaaaagctg
aaggaagagagagaagctcgagaaaaggctgaaaatagggttgttcagattgagaaacag
tgttccatgctagatgttgatctgaaacaatctcagcagaagcttgaacatttgactgaa
agtaaagaaagaatggaggatgaagttaagaatcttactctgcaattggagcaggaatca
aataagcgactcttctttcaaaatgaattgaagactcaagcatttgaggcagacaattta
aaaggtctagaaaagcagatgaaacaggaaataaatactttactggaagcaaagagatta
ttagaatttgaattagctcaacttacaaaacaatatagaggaaatgaaggacagatgcgg
gaactacaagatcaacttgaagctgaacaatatttctcgacactttataaaacccaggta
aaggaactgaaggaagaaattgaagaaaaaaacagagaaaatttaaaaaaaatacaggaa
ctacaaaatgagaaagaaactcttgctactcagctggatctagcggaaacaaaagctgag
tctgagcagttggctcgagggcttttagaagaacagtactttgaattgacccaagaaagc
aagaaagctgcttcaagaaacagacaagagattacagataaagatcacactgttagtcgg
cttgaggaaatgaacagtatgctaaccaaagatgttgaattattaagaaaagaaaatgaa
gagctaactgataaaatgaggaaatcagaggaagatttcaaacagaagaaagaggaggag
atcaataatcttaaggctgcctttgaaaagaatatcagtacagaacgaactcttaaaaca
caggctgttaacaagttggcagaaataatgaatcgaaaagactttaaaattgatagaaag
aaagctaatacacaggatttgaggaagaaagaaaaggaaaatcgaaagctacaactggaa
ctcaaccaagaaagagagaaattcaaccagatggtagtgaaacatcagaaggaactgaat
gacatgcaagcgcaattggtagaagaatgtacacataggaatgagcttcaaatgcagttg
gctagcaaagagagtgatatcgagcaattgcgtgctaaacttctggacctatcggattct
acgagtgttgctagtttgcctagtgctgatgaaactgatggaaaccttccagagtcaaga
attgaaggttggctttcaataccaaatagaggaaatatcaaacgatatggctggaagaaa
cagtatgttgtggtaagcagcaagaaaattttattttataacgatgaacaagataaggaa
caatccaatccatctatggtattagacatagataaattgttccatgttcgacctgtaacc
caaggagatgtgtatagagctgaaactgaagaaattcctaaaatatttcagatactttat
gcaaatgaaggtgaatgtagaaaagatgtagagatggaaccagtacaacaagctgaaaaa
actaattttcagaatcacaaaggccatgagttcattcctacactctaccactttcccgcc
aactgtgaggcctgtgccaaacctctctggcatgtttttaagccaccccctgccctagaa
tgtcgaagatgccatgttaagtgccacagagatcatttagataagaaagaggacctaatt
tctccatgtaaagtaagttatgatgtaacatcagcaagagatatgctgttgttagcatgt
tctcaggatgaacaaaagaaatgggtaactcatttagtgaaaaagatacctaagaatcca
ccatctggttttgttcgtgcatcccctcgaacactttctacaagatccactgcaaatcaa
tctttccggaaagtggttaaaaatacatctggaaaaactagttaa

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