Pipistrellus kuhlii (Kuhl's pipistrelle): 118711157
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Entry
118711157 CDS
T07682
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
pkl
Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl00310
Lysine degradation
pkl01100
Metabolic pathways
pkl05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
pkl00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
118711157 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
118711157 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pkl03036
]
118711157 (DOT1L)
Enzymes [BR:
pkl01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
118711157 (DOT1L)
Chromosome and associated proteins [BR:
pkl03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
118711157 (DOT1L)
HMT complexes
Dot1-containing complex
118711157 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
118711157
NCBI-ProteinID:
XP_036280019
LinkDB
All DBs
Position
Unknown
AA seq
1730 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTSVDSGAEEEKAATTAIKKPSPSKARKKKLNKKGRKLAGRKRGRPKKMSTA
NPERKPKKSPTALDLLHAQTVSQTAAPSPQDAYKSPHSPFYQLPPSVQRHPPDQLLLAPT
PPGLQKLLESFKIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKKLFQQKLDELGVKALTYSDLIQAQKEISAHNQQLREQTEQLEKDNRELRSQSLQLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDEAVPLHLRGQGGLGRELEAEPSRLPRELDCSKFSLPHFSSMSPELSMNGHAAGY
ELCSTLSRPSSKQNTPQYLASPLDQEVVPCTPSHGSRPRLEKLSGLALPDYTRLSPAKLV
LRRHLSQDHTASGKTSAGELHPRTEHAKENGLPYQSPGLANGIKLSPQDQRPSSPAALQM
TGDKGSEKGLKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPNRAEKRSTP
SPVHQTRESSSTLEKQMGTNAHGAGSNAVGSKSLTLAPAGFYAGSVAISGALAGSPAPLA
PGVEPPAFDESSSSGSLFATMGSRSSTPQHPQLLVQPRNSGPASPSHQLCVSPRLSAAQG
PLPDASKGDLPSEVGFSDPESEAKRRIIFTISAGASSTKQSPSNKHSPLPGGARGDSSQS
HGQDSRKRGRRKRASAGTPSLSSGVSPKRRALPTVAGLFTQSSGSPLNLNSMVNNINQPL
EITAISSPESSLKSSPAPYQDNDQPPVLKKEKPLSQPNGVHYSPLTSDEEPGSEDEQGST
RIERKIATISLESKSPPKTLENGGTLVGRKPMPSSEPINSSKWKSTFSPIADLGLAKATD
SPLQASSALSQNSLFAFRPTLEELSSVDAKLVTHPRKSFPGALSGAGGLSPISTPPNGFA
FSGSLAADLSLHSFSDGASLSHKAPEVASLGAPLSFSAPRGKESSTEPGPFVNKRQLDGL
GGPKGEGVKGREGEVSLPVSTPSDKASSHGKVGKGRDREPDFKNGHNLFISAAAGPPGGL
LSGPGLTTAASSASGTAPSSQTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSLFSSVP
AAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGIFNHTVPSASTHPFGASFGSGAACR
STTLSLTPMQAVASTPASSFQALSSVETRQPPPQPPLPLGRPPAGPPALHAPPPPPNAAL
PPAPALLPANSEPVLLQNLAPLPANQAFLPASSAASLPPANASLSVKLASLPHKVSRPSF
VVHHQPLPGLALAQASPMIPQASSTGPSAVWVSLGMPPPYAARLAGVKPR
NT seq
5193 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccacgatgctgctcatgaaatcatcgagacc
atccgatgggtctgtgaggaaatcccagacctcaagcttgctatggagaattacgtccta
atcgactacgacaccaaaagctttgaaagcatgcagaggctctgtgacaagtacaatcgg
gccattgacagcatccaccagctgtggaagggaaccacgcagcccatgaagctgaacacg
cggccatccaatgggctcctgcggcacatcctgcagcaggtttacaaccactcagtgacg
gaccctgagaagctcaacaactacgagcccttctccccagaggtttatggggaaacctcc
tttgacctggtcgcacagatgattgacgagatcaagatgaccgaggacgacctgtttgtg
gacctgggaagtggagtgggccaggtcgtgctgcaagtcgccgcggccaccaactgtaaa
catcactacggagtcgagaaagcggacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggtgattttctctcggaggagtggagagagcggatcgccaacacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaacatg
aaggaaggtggcagaattgtgtcctcgaagccctttgcacctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctctcgcccctgaag
ggctcagtgtcgtggacggggaagcccgtctcctactacctgcacaccatcgaccgtacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggaacaagaggca
gctaggcgtcggcagcagcgagaaaacaagagtaatacaaccacccccacgaaggtgcct
gagagcaaggcggctgtgcctgcggacacctctgtggattctggtgctgaggaagagaaa
gcagcgaccaccgctatcaagaagccatcgccctccaaagctcggaagaagaagctgaac
aagaagggccggaagctggctggccggaagcgtgggcgtcccaagaagatgagcaccgcg
aaccccgagcgcaagcccaagaagagccctactgccctggacctcctgcacgcccagact
gtgtcccagacggcggcgccctcgccacaagatgcatacaagtcacctcacagcccattt
tatcagctacctcccagcgtgcagcggcacccccctgaccagctgttgctggcacccacc
ccgcctggactgcagaagctgctagagtccttcaagattcagtacctgcagttcctggcg
tacacgaagacccctcagtacaaggccagcctgcagcagctgctggaccaggagaaggag
aagaacgcccggttgctgggtgccgcacagcagctgtttggtcactgccaggcccagaaa
gaagaaataaagaagctttttcagcagaaactggatgagttgggagtgaaggcgctgacc
tacagtgacctgatccaagctcagaaagagatctccgctcacaaccagcagctgcgagag
cagacggagcagctggagaaggacaacagggaactgagaagccagagcctgcagctgctg
aaggctcggtgtgaggagctgaagttggactggtccacactgtccctggagaacctgcta
aaggagaagcaggccctgaagagccagatctctgagaaacagaggcactgcctggagctg
cagatcagcatcgtggagctggagaagagccagcggcagcaggagctcctgcagctcaag
tcctgcgtgccgcctgatgaagctgtgcccctgcacctgcgagggcaaggtggcctgggc
cgagagctggaggcggagcccagccggctgccccgtgagctggactgctccaaattctca
ctgccccacttcagcagcatgagcccggagctctccatgaatggccacgcggctggctat
gagctctgcagcacactgagccggccctcgtccaagcagaacaccccccagtacctggcc
tctccactggaccaggaggttgtgccatgcactcccagccacggcagccggcctcggctt
gagaagctgtctggcttggccttgccagactacaccaggctctccccggccaagctggtg
ctgagacgccacctgagccaggaccacactgccagtggcaagacatctgctggtgagcta
cacccacgaactgagcacgccaaggagaatggccttccataccagagcccgggcctcgcc
aatggcatcaagctgagccctcaggaccaacggccctcatcccctgcggccttacagatg
acaggagacaaaggcagtgagaagggtctgaaggagcgagcctatgccagcagtggggag
gccatcaccagcctacccgtcagcattccactcagcactgtgcagcccagcaagctgccc
gtcagcatccccctggccagcgtggtgttgcccaaccgtgccgagaagagaagcaccccc
agtcccgtgcatcagacccgagagtcctcgtccacacttgaaaagcagatgggtactaat
gcccatggtgctgggagcaacgctgttgggagcaaaagcctcaccctggcgcctgcaggc
ttctatgcaggctctgtcgccatcagtggggccctggcaggcagcccggccccactcgct
cctggagttgagccccctgccttcgatgagtcctccagctccgggagtctcttcgccacc
atgggctcccgcagctccaccccacagcatcctcagctgctcgtgcagccccggaactcc
ggtcccgcctcgccctctcaccagctctgcgtcagcccccgactcagtgccgcccagggc
ccactccctgatgcgagcaaaggggaccttccctctgaggttggcttctcagatccagag
agcgaggccaagaggaggattatcttcaccatctcagctggtgccagcagcaccaagcag
tcaccttccaacaagcacagccctctgcctgggggtgctcgtggagacagcagtcagagc
cacgggcaggacagtcgaaaacggggtagaaggaagcgagcatcagcggggacccccagt
ctgagctcaggcgtatcccccaagcgccgggccttgccaaccgtcgccggcctcttcact
cagtcttcaggttctcccctcaacctgaactccatggtcaacaacattaaccagcctttg
gagatcacagccatctcgtcccccgagagctccctgaagagctcccctgcaccataccag
gacaacgaccagccccccgtgctcaagaaggagaagcccctgagccagcccaatggggtc
cactactccccactgacctccgatgaagagccgggctctgaggatgagcaaggcagcacc
agaattgagagaaaaattgcaactatctccttagaaagcaaatctcctccgaaaaccttg
gaaaatggtggcaccctggtaggaaggaagccgatgccctccagcgagcccatcaacagc
agcaagtggaagtccaccttctcacccatcgctgaccttggcctggccaaggccactgac
agcccgctacaggccagctccgctctgagccagaactccctgttcgcttttcggcccacc
ctagaggagctcagctcagttgatgccaagctggtcacccaccccaggaagagctttccg
ggtgcactgtcgggggctggcgggctgagtcccatcagcaccccccccaacggctttgct
ttcagcgggagcctggctgccgacctcagtttacacagtttcagtgatggtgcttctctc
tcccacaaggcccctgaggtggccagcctgggcgcccccctgagcttttccgccccgagg
ggtaaggagagcagcacggagcctggcccttttgtgaacaagaggcagctggatggactg
ggtggcccaaagggtgagggcgtcaagggcagggagggagaagtcagcttgcctgtgagc
acaccctcagacaaggcctcgtcacatggcaaggtgggcaagggccgggaccgcgagcct
gatttcaaaaacggccacaatctcttcatttctgccgctgccgggcctcctgggggcctc
ctcagtgggcccggcctcaccacggctgcgtcctcagcaagcggcacagccccctcctcc
cagacacaccggcccttcctgggcacttttgcacctggcccacagtttgccttgggcccc
atgtccctgcaggccaacttaggctcatctgtgctacagtccttgttcagctctgtgccg
gctgctgctggcctagtgcacgtctcatccgctgcaaccagactgaccaactctcatgcc
atgggcagcttttcctccggtgtggcaggtggtgcagttggaggtatctttaaccacacg
gtgccttccgcctccactcatccgtttggagccagtttcggcagcggggctgcttgtcgc
agcaccacgctgagcttaaccccgatgcaggcggtggccagtacccccgcctcttccttt
caggccctgtcctctgtggagaccaggcagcccccaccccagcctcctctgcccctgggt
cggccccctgcggggccaccagcacttcacgcgcccccccctcctcctaacgctgccttg
cctcctgctcctgcactgctccctgctaactctgagcctgtgctcctgcagaatcttgcg
cccctcccggctaaccaagctttcttacctgcctcctctgccgcctctctgcctcctgct
aacgcctctctgtctgtcaagctcgcatccctcccacacaaggtctcccgcccctccttt
gtggtgcaccaccagccactgcctggactggctctggcccaggcctcacccatgatccca
caggccagctccacggggccgtccgccgtgtgggtttcccttggcatgccgcctccttat
gccgcgcgccttgcgggggttaagccgcgataa
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integrated database retrieval system
