KEGG   Pipistrellus kuhlii (Kuhl's pipistrelle): 118714741
Entry
118714741         CDS       T07682                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
pkl  Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl01522  Endocrine resistance
pkl04010  MAPK signaling pathway
pkl04015  Rap1 signaling pathway
pkl04068  FoxO signaling pathway
pkl04071  Sphingolipid signaling pathway
pkl04114  Oocyte meiosis
pkl04148  Efferocytosis
pkl04218  Cellular senescence
pkl04261  Adrenergic signaling in cardiomyocytes
pkl04370  VEGF signaling pathway
pkl04380  Osteoclast differentiation
pkl04550  Signaling pathways regulating pluripotency of stem cells
pkl04611  Platelet activation
pkl04613  Neutrophil extracellular trap formation
pkl04620  Toll-like receptor signaling pathway
pkl04621  NOD-like receptor signaling pathway
pkl04622  RIG-I-like receptor signaling pathway
pkl04625  C-type lectin receptor signaling pathway
pkl04657  IL-17 signaling pathway
pkl04658  Th1 and Th2 cell differentiation
pkl04659  Th17 cell differentiation
pkl04660  T cell receptor signaling pathway
pkl04664  Fc epsilon RI signaling pathway
pkl04668  TNF signaling pathway
pkl04670  Leukocyte transendothelial migration
pkl04714  Thermogenesis
pkl04722  Neurotrophin signaling pathway
pkl04723  Retrograde endocannabinoid signaling
pkl04728  Dopaminergic synapse
pkl04750  Inflammatory mediator regulation of TRP channels
pkl04912  GnRH signaling pathway
pkl04914  Progesterone-mediated oocyte maturation
pkl04917  Prolactin signaling pathway
pkl04926  Relaxin signaling pathway
pkl04932  Non-alcoholic fatty liver disease
pkl04933  AGE-RAGE signaling pathway in diabetic complications
pkl04935  Growth hormone synthesis, secretion and action
pkl04936  Alcoholic liver disease
pkl05014  Amyotrophic lateral sclerosis
pkl05020  Prion disease
pkl05022  Pathways of neurodegeneration - multiple diseases
pkl05132  Salmonella infection
pkl05133  Pertussis
pkl05135  Yersinia infection
pkl05140  Leishmaniasis
pkl05142  Chagas disease
pkl05145  Toxoplasmosis
pkl05152  Tuberculosis
pkl05161  Hepatitis B
pkl05163  Human cytomegalovirus infection
pkl05167  Kaposi sarcoma-associated herpesvirus infection
pkl05169  Epstein-Barr virus infection
pkl05170  Human immunodeficiency virus 1 infection
pkl05171  Coronavirus disease - COVID-19
pkl05205  Proteoglycans in cancer
pkl05208  Chemical carcinogenesis - reactive oxygen species
pkl05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pkl05415  Diabetic cardiomyopathy
pkl05417  Lipid and atherosclerosis
pkl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pkl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118714741 (MAPK11)
   04015 Rap1 signaling pathway
    118714741 (MAPK11)
   04370 VEGF signaling pathway
    118714741 (MAPK11)
   04668 TNF signaling pathway
    118714741 (MAPK11)
   04068 FoxO signaling pathway
    118714741 (MAPK11)
   04071 Sphingolipid signaling pathway
    118714741 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    118714741 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    118714741 (MAPK11)
   04218 Cellular senescence
    118714741 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    118714741 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118714741 (MAPK11)
   04613 Neutrophil extracellular trap formation
    118714741 (MAPK11)
   04620 Toll-like receptor signaling pathway
    118714741 (MAPK11)
   04621 NOD-like receptor signaling pathway
    118714741 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    118714741 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    118714741 (MAPK11)
   04660 T cell receptor signaling pathway
    118714741 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    118714741 (MAPK11)
   04659 Th17 cell differentiation
    118714741 (MAPK11)
   04657 IL-17 signaling pathway
    118714741 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    118714741 (MAPK11)
   04670 Leukocyte transendothelial migration
    118714741 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    118714741 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    118714741 (MAPK11)
   04917 Prolactin signaling pathway
    118714741 (MAPK11)
   04926 Relaxin signaling pathway
    118714741 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    118714741 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    118714741 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    118714741 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    118714741 (MAPK11)
   04722 Neurotrophin signaling pathway
    118714741 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    118714741 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118714741 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    118714741 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    118714741 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    118714741 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118714741 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    118714741 (MAPK11)
   05161 Hepatitis B
    118714741 (MAPK11)
   05171 Coronavirus disease - COVID-19
    118714741 (MAPK11)
   05163 Human cytomegalovirus infection
    118714741 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118714741 (MAPK11)
   05169 Epstein-Barr virus infection
    118714741 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118714741 (MAPK11)
   05135 Yersinia infection
    118714741 (MAPK11)
   05133 Pertussis
    118714741 (MAPK11)
   05152 Tuberculosis
    118714741 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    118714741 (MAPK11)
   05140 Leishmaniasis
    118714741 (MAPK11)
   05142 Chagas disease
    118714741 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    118714741 (MAPK11)
   05020 Prion disease
    118714741 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    118714741 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118714741 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    118714741 (MAPK11)
   05415 Diabetic cardiomyopathy
    118714741 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    118714741 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    118714741 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    118714741 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    118714741 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pkl01001]
    118714741 (MAPK11)
Enzymes [BR:pkl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     118714741 (MAPK11)
Protein kinases [BR:pkl01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   118714741 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Kinase-like FTA2 Cas_CT1975
Other DBs
NCBI-GeneID: 118714741
NCBI-ProteinID: XP_036285995
LinkDB
Position
Unknown
AA seq 365 aa
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLVHARRTYRELRLLQHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIVHRDLKPSNLAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTAVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVV
GTPSPEVLAKISSEHARTYIQSLPPMPGKDLRSIFRGANPLAVDLLGRMLVLDSDQRLSA
AEALAHAYFSQYHDPEDEPEAEPYDESVEATERTLEEWKELTYQEVLSFKPPGPPQPPGS
LDMEQ
NT seq 1098 nt   +upstreamnt  +downstreamnt
atgtccgggccgcgcgccggcttctaccggcaggagctcaacaagacggtgtgggaggtg
ccgcagcggctgcaggggctgcgcccggtgggctcgggcgcctacggctccgtctgctcg
gcctacgacgcgcggctccgccagaaggtggcggtgaagaagctgtcgcgccccttccag
tcgctggtccacgcgcggaggacctaccgggagctgcggctgctgcagcacctgaagcac
gagaacgtcatcgggctgctggacgtcttcacgccggccacgtccatcgaggacttcagc
gaagtgtacctggtgaccacgctgatgggcgccgacctcaacaacatcgtcaagtgccag
gcgctgagcgacgagcacgtgcagttcctggtgtaccagctgctgcgcgggctgaagtac
atccactcggccgggatcgtccaccgggacctgaagcccagcaacctggcggtgaacgag
gactgcgagctcaggatcctggacttcgggctggcgcgccaggcagacgaggagatgacg
ggctacgtggccacgcgctggtaccgggcccctgagatcatgctcaactggatgcactac
aaccagacagcagtggacatctggtctgtgggttgcatcatggctgagctgctccaagga
aaggccctcttcccgggaagtgactatattgaccagctgaagcgcatcatggaggtggtg
ggcacgcccagccctgaggtgctggccaagatctcctcggagcacgcccggacgtacatc
cagtccctgcctcccatgcccgggaaggacctcaggagcatcttccgtggcgccaacccc
ctggccgtggacctcctggggaggatgctggtgctggacagcgaccagcggctcagcgcg
gccgaggccctggcccacgcctacttcagccagtaccacgaccccgaggacgagcccgag
gccgagccctatgacgagagcgtggaggccacggagcgcaccctggaggagtggaaggag
ctcacctaccaggaagtcctcagcttcaagcccccggggccaccgcagcctccgggcagc
ctggacatggagcagtga

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