Pipistrellus kuhlii (Kuhl's pipistrelle): 118716057
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Entry
118716057 CDS
T07682
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
pkl
Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl00230
Purine metabolism
pkl00670
One carbon pool by folate
pkl01100
Metabolic pathways
pkl01523
Antifolate resistance
Module
pkl_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
pkl00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
118716057 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
118716057 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
118716057 (GART)
Enzymes [BR:
pkl01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
118716057 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
118716057 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
118716057 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_4
ATP-grasp_2
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
118716057
NCBI-ProteinID:
XP_036288644
LinkDB
All DBs
Position
Unknown
AA seq
1009 aa
AA seq
DB search
MAARVLVVGSGGREHTLAWSLARSPHVRQVLVAPGNAGTAGSEKISNAAISISDHSALAQ
FCKDENIEFVVVGPEAPLAAGMVGDLAAAGVRCFGPTAQAAQLESSKRFAKEFMDRHGIP
TARWRAFTELEEARSFILSADFPALVVKASGLAAGKGVIVAASREEACRAVQDIMQDKAF
GAAGETVVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDRGPNTGGMGACCPAP
QVSKDLLLKIKNAILQRTVDGMQQEGTPYTGVLYAGVMLTRDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCAAPPVWLENQAAVTVVMASQGYPGDYTKGVEITGVAKA
QALGLEVFQAGTALKDGKVVTSGGRVLTVTAIRDTVVAALEAAKQGLAAIKFEGAVYRTD
IGGRAIAFLQQPRGLTYKDSGVDIAAGNLLVKHIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGYRDPLLVSGTDGVGTKLKIAQQCEQHGTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GNLDVGTAAAVVAGIAEACRKAGCALLGGETAEMPGMYAPGEYDLAGFAVGAVERDQQLP
RLESIAEGDVVIGVASSGLHSNGFSLVRKIVAKSSLQYSSPAPPGCGHQALGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPPSCGAELDAQAWRVPAIFSWLQREG
CLSAEEMARTFNCGLGAALVVSPDLAEQVLRDVRQHQEEAWLVGRVVARPEGSPRVRVRH
LLDALQPSGPALHNGPAPGPLSAPEKARVAVLISGTGSNLQALIDSTREPSSAAHIVLVI
SNKAAVAGLDRAARAGIPTRVLNHKLYKSRVEFDEAIDQILAEFSVDIVCLAGFMRILSG
PFVRKWNGRMLNIHPSLLPAFKGANAHEQALATGVALTGCTVHFVAEDVDAGRIILQEAV
PVKRGDTVATLSERVKVAEHRIFPAALQLVASGAVRLGEDGRLRWAQEE
NT seq
3030 nt
NT seq
+upstream
nt +downstream
nt
atggccgcccgagtgctcgtcgtgggcagcgggggccgagagcacaccctggcctggagc
ctggcgcggtctccccacgtcagacaggtgttggtcgcccccggaaatgcaggcactgcc
ggctccgagaagatttcaaacgccgccatctccatcagcgaccacagtgccctcgctcag
ttctgcaaagatgagaacattgaattcgtcgttgttggaccagaggcacctctggctgct
gggatggtcggggacctggcggcggcaggcgtgcggtgctttggccccacagcacaagcg
gctcagctagagtccagcaaaaggttcgccaaggagttcatggaccggcacggcatccca
accgcccggtggagggccttcaccgagctggaggaggcccgcagcttcatcctgagcgca
gacttccctgctctggtcgtgaaggccagcggcctggccgccgggaagggggtgatcgtg
gcagcgagcagagaagaggcttgcagagccgtgcaggacatcatgcaggataaagccttt
ggagcggcgggagaaacggttgtcattgaagagctgctggaaggagaagaggtttcttgt
ctgtgcttcaccgacgggcggaccgtggctcccatgcccccggcgcaggaccacaagcgg
ctgctggagggagaccgaggccccaacacagggggcatgggggcttgctgccccgcccca
caggtctctaaggatttgctgctgaagattaaaaatgccatccttcagcggacagtggac
ggcatgcagcaggagggcacgccgtacacaggtgttctctacgcgggcgtgatgctgacc
agggatggcccaaaggttctggagtttaactgccgtttcggggacccagagtgccaggtg
atcctcccgcttcttaagagcgatctctacgaggtgattcagtccaccctcgatggcctg
ctctgcgcagctccgcccgtttggcttgaaaaccaggcggctgtcaccgtcgtcatggca
agtcaggggtatcctggagactacaccaagggcgtagagataacaggcgtcgccaaggcc
caggctttggggctagaggtgttccaggcaggcacagccctgaaagacggcaaagtggtg
accagcggagggcgagtcctcacggtgaccgccatccgggacacagtcgtcgcagccctc
gaagcagccaagcaaggactggctgctataaagtttgagggcgccgtctacaggaccgac
attggcggccgcgccatagcgttcctgcagcagcccaggggcctgacgtacaaggactcg
ggggtcgacattgcagctggaaatctgctggtcaagcacattaagcctctagccaaagcc
acctccagaccaggctgtgatgtggatctgggaggttttgctggtctttttgacctgaaa
gcagcagggtacagagaccctctcctggtcagcggaacagatggcgtcggcacgaaactg
aagattgcccagcagtgcgagcagcacggcaccatcggccaggacttggttgcgatgtgc
gtgaacgatatcctggcccagggcgcagagcccctcttcttcctcgactacttttcctgt
gggaacctcgacgtgggcaccgctgcagccgttgtcgctggcatcgccgaagcgtgcagg
aaagctgggtgcgccctcctcgggggggaaacggcggaaatgccgggcatgtacgccccc
ggggagtacgacctggccggcttcgccgtgggcgcggtggagcgcgaccagcagctccct
cgcctggaaagcatcgctgagggggatgttgtgatcggagtggcgtcgtctggtctccac
agcaacgggttcagccttgtgaggaagatagtagcgaagtcctccctccagtactcctcc
ccggcgccccccggctgcggccaccaggccttaggagacttacttctgactccgaccaga
atctacagccactccctgctacctgtgttgcgttcaggccacgtcaaggcctttgcccac
atcaccggcggcgggctgctggagaacatcccgcgggtcctccctccgagctgcggggca
gagctagatgcccaggcctggagggtgcccgccatcttctcgtggctgcagcgcgaagga
tgcctgtcggccgaggagatggccaggacctttaactgcgggctcggcgctgccctggtg
gtgtcgccggacctggcggagcaggtgctgagggacgttcggcagcaccaggaggaggcc
tggctggtcggccgggtggtggcccgccctgaaggttccccccgagtgagagtccggcac
ctgctggacgccctgcagccgagtgggcccgcgctgcacaacggccctgcgcccggtccc
ctctcagccccggagaaggccagggtggccgtcctcatctccgggacaggctcgaacctg
caggcgctgatagacagcacccgggagccgagcagcgccgcccacatcgtcctggtcatc
tccaacaaggccgcggtggccgggttggaccgagcagcccgtgcgggcattcccaccagg
gtgcttaatcacaagctatataaaagccgtgtcgaatttgacgaggccattgaccagatt
cttgcagagttctccgtggacatcgtctgtctggcagggttcatgaggatattgtccggc
cccttcgtcaggaagtggaatgggagaatgctcaacatccacccgtccctgctgccggcc
ttcaagggcgccaatgcccacgagcaggccctggccaccggcgtcgcgctgacagggtgc
accgtgcacttcgtcgctgaggacgtggatgccgggcggattatcttacaggaagctgtg
ccggtgaagaggggcgacaccgtggccaccctgtccgagagggtgaaggtggcggagcac
aggatcttccccgccgccttgcaactggtggccagcggcgccgtgcggctgggcgaggac
ggccggctccgctgggcccaggaggagtga
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