KEGG   Pipistrellus kuhlii (Kuhl's pipistrelle): 118717241
Entry
118717241         CDS       T07682                                 
Symbol
ADCY3
Name
(RefSeq) adenylate cyclase type 3 isoform X1
  KO
K08043  adenylate cyclase 3 [EC:4.6.1.1]
Organism
pkl  Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl00230  Purine metabolism
pkl01100  Metabolic pathways
pkl01522  Endocrine resistance
pkl04015  Rap1 signaling pathway
pkl04020  Calcium signaling pathway
pkl04022  cGMP-PKG signaling pathway
pkl04024  cAMP signaling pathway
pkl04062  Chemokine signaling pathway
pkl04072  Phospholipase D signaling pathway
pkl04081  Hormone signaling
pkl04082  Neuroactive ligand signaling
pkl04114  Oocyte meiosis
pkl04211  Longevity regulating pathway
pkl04213  Longevity regulating pathway - multiple species
pkl04261  Adrenergic signaling in cardiomyocytes
pkl04270  Vascular smooth muscle contraction
pkl04371  Apelin signaling pathway
pkl04540  Gap junction
pkl04611  Platelet activation
pkl04713  Circadian entrainment
pkl04714  Thermogenesis
pkl04723  Retrograde endocannabinoid signaling
pkl04724  Glutamatergic synapse
pkl04725  Cholinergic synapse
pkl04727  GABAergic synapse
pkl04740  Olfactory transduction
pkl04750  Inflammatory mediator regulation of TRP channels
pkl04911  Insulin secretion
pkl04912  GnRH signaling pathway
pkl04913  Ovarian steroidogenesis
pkl04914  Progesterone-mediated oocyte maturation
pkl04915  Estrogen signaling pathway
pkl04916  Melanogenesis
pkl04918  Thyroid hormone synthesis
pkl04921  Oxytocin signaling pathway
pkl04923  Regulation of lipolysis in adipocytes
pkl04925  Aldosterone synthesis and secretion
pkl04926  Relaxin signaling pathway
pkl04927  Cortisol synthesis and secretion
pkl04928  Parathyroid hormone synthesis, secretion and action
pkl04934  Cushing syndrome
pkl04935  Growth hormone synthesis, secretion and action
pkl04962  Vasopressin-regulated water reabsorption
pkl04970  Salivary secretion
pkl04971  Gastric acid secretion
pkl04972  Pancreatic secretion
pkl04976  Bile secretion
pkl05032  Morphine addiction
pkl05163  Human cytomegalovirus infection
pkl05166  Human T-cell leukemia virus 1 infection
pkl05200  Pathways in cancer
pkl05207  Chemical carcinogenesis - receptor activation
pkl05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pkl00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    118717241 (ADCY3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    118717241 (ADCY3)
   04371 Apelin signaling pathway
    118717241 (ADCY3)
   04020 Calcium signaling pathway
    118717241 (ADCY3)
   04072 Phospholipase D signaling pathway
    118717241 (ADCY3)
   04024 cAMP signaling pathway
    118717241 (ADCY3)
   04022 cGMP-PKG signaling pathway
    118717241 (ADCY3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    118717241 (ADCY3)
   04081 Hormone signaling
    118717241 (ADCY3)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    118717241 (ADCY3)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    118717241 (ADCY3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118717241 (ADCY3)
   04062 Chemokine signaling pathway
    118717241 (ADCY3)
  09152 Endocrine system
   04911 Insulin secretion
    118717241 (ADCY3)
   04923 Regulation of lipolysis in adipocytes
    118717241 (ADCY3)
   04912 GnRH signaling pathway
    118717241 (ADCY3)
   04913 Ovarian steroidogenesis
    118717241 (ADCY3)
   04915 Estrogen signaling pathway
    118717241 (ADCY3)
   04914 Progesterone-mediated oocyte maturation
    118717241 (ADCY3)
   04921 Oxytocin signaling pathway
    118717241 (ADCY3)
   04926 Relaxin signaling pathway
    118717241 (ADCY3)
   04935 Growth hormone synthesis, secretion and action
    118717241 (ADCY3)
   04918 Thyroid hormone synthesis
    118717241 (ADCY3)
   04928 Parathyroid hormone synthesis, secretion and action
    118717241 (ADCY3)
   04916 Melanogenesis
    118717241 (ADCY3)
   04925 Aldosterone synthesis and secretion
    118717241 (ADCY3)
   04927 Cortisol synthesis and secretion
    118717241 (ADCY3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    118717241 (ADCY3)
   04270 Vascular smooth muscle contraction
    118717241 (ADCY3)
  09154 Digestive system
   04970 Salivary secretion
    118717241 (ADCY3)
   04971 Gastric acid secretion
    118717241 (ADCY3)
   04972 Pancreatic secretion
    118717241 (ADCY3)
   04976 Bile secretion
    118717241 (ADCY3)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    118717241 (ADCY3)
  09156 Nervous system
   04724 Glutamatergic synapse
    118717241 (ADCY3)
   04727 GABAergic synapse
    118717241 (ADCY3)
   04725 Cholinergic synapse
    118717241 (ADCY3)
   04723 Retrograde endocannabinoid signaling
    118717241 (ADCY3)
  09157 Sensory system
   04740 Olfactory transduction
    118717241 (ADCY3)
   04750 Inflammatory mediator regulation of TRP channels
    118717241 (ADCY3)
  09149 Aging
   04211 Longevity regulating pathway
    118717241 (ADCY3)
   04213 Longevity regulating pathway - multiple species
    118717241 (ADCY3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    118717241 (ADCY3)
   04714 Thermogenesis
    118717241 (ADCY3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118717241 (ADCY3)
   05207 Chemical carcinogenesis - receptor activation
    118717241 (ADCY3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118717241 (ADCY3)
   05163 Human cytomegalovirus infection
    118717241 (ADCY3)
  09165 Substance dependence
   05032 Morphine addiction
    118717241 (ADCY3)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    118717241 (ADCY3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    118717241 (ADCY3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    118717241 (ADCY3)
Enzymes [BR:pkl01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     118717241 (ADCY3)
SSDB
Motif
Pfam: Guanylate_cyc AC_N HNOBA
Other DBs
NCBI-GeneID: 118717241
NCBI-ProteinID: XP_036290939
LinkDB
Position
Unknown
AA seq 1150 aa
MPRHRQGSFEPEQPSAAEPSASLPSDPDALRAGRTHEVSVRSVGACLCLPGCLRPTFVPE
SLESLYQTYFRRQRHETLLVLVVFAALFAGHALAVCAAAFSADRLAPLAAAGAGLLLDAL
LFVLCRKGLLPSRVTRRAVPYLLWLLISAQIFAHLGLSVPAGAHAASDTVGWQAFFVFSF
FITLPLGLSPIVVLSVVSCAAHTLVLGVTVAQQQQRQQDRLKGMQLLREILANVFLYLGA
IAVGIMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMK
KDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSTCSAQELVKLLNELFARFDKLAA
KYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVH
TGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGEGG
SRCDYLEEKGIETYLIIASRPEVKKTASQNGLGSSALPNGAPASSKPSSPALIETKESNG
SVHTSGSTSEENEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNQALLE
RESAQVVKKRNTFLLSMRFMDPELETRYSVEKEKQSGAAFSCSCVVLLCTALVEIVIDPW
LMTNYVTFVVGELLLLVLTVCSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFIL
VMANVVDMLSCLQYYRGPNNGTSGMATEDGCMENPKYYNYVAVLSLVATIMLVQVSHMVK
LTLMLLITGAVAVINLCAWSPIFDEYDRRRFQEPGSFPLVALEKMQILSTPGLNGTGRLP
LVPSKYTMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTN
MLPDHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNE
IISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKEEKSDKERWQHLA
DLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRM
ESTGVMGNIQVVEETQAILREYGFRFVRRGPVFVKGKGELLTFFLKGRDKPAAFPNGASV
TLPHQVVDNS
NT seq 3453 nt   +upstreamnt  +downstreamnt
atgcccaggcaccggcagggctccttcgagcccgagcagccctccgccgccgagccctcg
gccagcctgccctcggaccccgacgcccttcgcgccggccgcacccacgaggtgtccgtg
cggagcgtgggcgcctgcctctgcctgcccggctgcctgcggcccaccttcgtgcccgag
tccctggagagcctctaccagacctacttccggcggcagcgccacgagacgctgctggtg
ctggtggtgttcgccgcgctcttcgccggccacgcgctggccgtgtgcgccgcggccttc
tcggcggaccgcctggccccgctggccgccgcgggcgccgggctgctgctggacgcgctc
ctgttcgtgctgtgccggaaggggctgctgcccagccgggtcacccgcagggccgtgccc
tacctgctgtggctgctcatctccgcgcagatcttcgcccacctgggcctcagcgtgccc
gccggcgcccacgccgccagcgacacggtgggctggcaggccttcttcgtcttctccttc
ttcatcacgctgcccctgggcctcagccccatcgtggtcctctccgtggtgtcctgtgcg
gcgcacacgctcgtgttgggggtcaccgtggcccagcagcagcagcggcagcaggacagg
ctgaaggggatgcagctgctgagggagatcctggccaatgtcttcctctacctgggcgcc
atcgccgtgggcatcatgtcctactacatggccgaccgcaagcaccgcaaggccttcctg
gaggcccgccagtcgctggaggtgaagatgaacctggaggagcagagccagcagcaggag
aacctgatgctctccatcctgcccaagcacgtggccgacgagatgctgaaggacatgaag
aaggacgagagccagaaggaccagcagcagttcaacaccatgtacatgtaccgccacgag
aacgtcagcatcctcttcgcagacatcgtgggcttcacacagctgtcttccacctgcagc
gcccaggagctcgtgaagctgctcaacgagctcttcgcccgcttcgacaagctggcggcc
aaataccaccagctgcgcattaagatcctgggcgactgctactactgcatctgcggcctg
ccggactaccgcgaggaccacgccgtctgctccatcctcatggggctcgccatggtggag
gccatctcgtacgtgcgggagaagaccaagaccggggtggacatgcgtgtgggggtgcac
acgggcacggtgctggggggcgtgctgggccagaagcgctggcagtacgacgtgtggtcc
accgacgtcaccgtggccaacaagatggaggccggcggcatccccgggcgcgtgcacatc
tcccagagcaccctggactgcctgaagggagagttcgacgtggagccgggcgaggggggc
agccgctgcgattacctggaggagaagggcattgaaacctacctcatcatcgcgtcccgg
ccggaggtgaagaaaaccgcctcccaaaacggcctcggcagctcggccctgcccaacgga
gcacccgcgtcctcaaagcccagctcccctgccctcatcgagaccaaggagtccaatggc
agcgtccacaccagcggctccacgtcggaggagaacgaggagcaggatgcccaggctgac
aacccctcgttccccaaccctcgccggaggctgcgccttcaggacctggctgaccgggtg
gtggacgcctctgaggatgagcacgaactcaaccagctcctcaaccaggccctgctcgag
cgggagtccgcgcaggtagtgaagaagaggaacaccttcctcctgtccatgcggttcatg
gaccccgagctggaaacacgctactcggtggagaaggagaagcagagcggggccgccttc
agctgctcctgcgtcgtgctgctctgcacggcgctggtggagatagtcatcgacccctgg
ctgatgaccaactatgtgacctttgtggttggggagcttctgctcctggtcctgacggtc
tgctcgctggcggccatctttccccgggcctttcctaagaagcttgtggccttctcgacg
tggattgaccggacacgctgggccaggaacacctgggccatgttagccatcttcattctg
gtcatggcaaatgtcgtggacatgctgagctgcctgcagtactacaggggacccaacaat
ggcacctcggggatggcgacggaggatggctgcatggagaaccccaagtattacaactac
gtggccgtgctgtccctcgtcgccaccatcatgctggtgcaggtcagccacatggtgaag
ctcaccctcatgctgctcatcaccggcgccgtggcagtcatcaacctctgtgcctggagc
cccatcttcgatgagtacgaccgcaggcgtttccaggaaccgggcagctttcccctggtc
gccttagagaagatgcagatcctctccacgcccgggctcaatggcactggcaggctgccc
ttggtgccttccaagtacacgatgacagtgatgatcttcgtcatgatgctgagcttctac
tacttctcccgccacgtggaaaaactcgcaaggacgctgttcttgtggaagatcgaggtc
cacgatcagaaggaacgtgtctacgagatgcgacgctggaacgaggccctggtcaccaac
atgttgcccgatcatgtggcccgccatttcctggggtccaagaagagagatgaggagctg
tatagccagtcttatgatgagattggagtcatgtttgcctccctacccaactttgctgac
ttctacacagaggagagcatcaataatggtggcattgagtgtctgcgcttcctcaatgag
atcatctcagactttgactctcttctagacaatcccaaattccgagtcatcaccaagatc
aaaaccattggcagtacctatatggcagcttccggagtcaccccagatgtcaacaccaat
ggctttaccagctccagcaaggaggagaagtcagacaaggagcgctggcagcacctggcc
gacctggctgactttgctctagccatgaaggacacgctcacaaacatcaacaaccagtcc
ttcaacaacttcatgctgcgcataggcatgaacaaaggaggggtcctggccggggtcatt
ggagcccggaaaccacactacgacatctggggcaatacggtcaatgtcgccagcaggatg
gagtccacaggggtcatgggtaacattcaggtggtagaagaaacgcaggccatccttcgc
gagtacggcttccgctttgtgaggcgcgggcccgtctttgtgaaagggaagggggagctg
ctcacctttttcttgaaggggcgcgacaagccagccgccttcccgaacggcgcctccgtg
accctgccccaccaggtagtggacaactcctga

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