Pipistrellus kuhlii (Kuhl's pipistrelle): 118720533
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Entry
118720533 CDS
T07682
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
pkl
Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl00562
Inositol phosphate metabolism
pkl01100
Metabolic pathways
pkl01521
EGFR tyrosine kinase inhibitor resistance
pkl04012
ErbB signaling pathway
pkl04014
Ras signaling pathway
pkl04020
Calcium signaling pathway
pkl04062
Chemokine signaling pathway
pkl04064
NF-kappa B signaling pathway
pkl04066
HIF-1 signaling pathway
pkl04070
Phosphatidylinositol signaling system
pkl04072
Phospholipase D signaling pathway
pkl04360
Axon guidance
pkl04370
VEGF signaling pathway
pkl04380
Osteoclast differentiation
pkl04611
Platelet activation
pkl04613
Neutrophil extracellular trap formation
pkl04625
C-type lectin receptor signaling pathway
pkl04650
Natural killer cell mediated cytotoxicity
pkl04662
B cell receptor signaling pathway
pkl04664
Fc epsilon RI signaling pathway
pkl04666
Fc gamma R-mediated phagocytosis
pkl04670
Leukocyte transendothelial migration
pkl04722
Neurotrophin signaling pathway
pkl04750
Inflammatory mediator regulation of TRP channels
pkl04919
Thyroid hormone signaling pathway
pkl04933
AGE-RAGE signaling pathway in diabetic complications
pkl04935
Growth hormone synthesis, secretion and action
pkl05167
Kaposi sarcoma-associated herpesvirus infection
pkl05169
Epstein-Barr virus infection
pkl05170
Human immunodeficiency virus 1 infection
pkl05171
Coronavirus disease - COVID-19
pkl05200
Pathways in cancer
pkl05205
Proteoglycans in cancer
pkl05206
MicroRNAs in cancer
pkl05214
Glioma
pkl05223
Non-small cell lung cancer
pkl05225
Hepatocellular carcinoma
Module
pkl_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
pkl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
118720533 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
118720533 (PLCG2)
04014 Ras signaling pathway
118720533 (PLCG2)
04370 VEGF signaling pathway
118720533 (PLCG2)
04064 NF-kappa B signaling pathway
118720533 (PLCG2)
04066 HIF-1 signaling pathway
118720533 (PLCG2)
04020 Calcium signaling pathway
118720533 (PLCG2)
04070 Phosphatidylinositol signaling system
118720533 (PLCG2)
04072 Phospholipase D signaling pathway
118720533 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
118720533 (PLCG2)
04613 Neutrophil extracellular trap formation
118720533 (PLCG2)
04625 C-type lectin receptor signaling pathway
118720533 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
118720533 (PLCG2)
04662 B cell receptor signaling pathway
118720533 (PLCG2)
04664 Fc epsilon RI signaling pathway
118720533 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
118720533 (PLCG2)
04670 Leukocyte transendothelial migration
118720533 (PLCG2)
04062 Chemokine signaling pathway
118720533 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
118720533 (PLCG2)
04919 Thyroid hormone signaling pathway
118720533 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
118720533 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
118720533 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
118720533 (PLCG2)
04380 Osteoclast differentiation
118720533 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118720533 (PLCG2)
05206 MicroRNAs in cancer
118720533 (PLCG2)
05205 Proteoglycans in cancer
118720533 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
118720533 (PLCG2)
05214 Glioma
118720533 (PLCG2)
05223 Non-small cell lung cancer
118720533 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
118720533 (PLCG2)
05171 Coronavirus disease - COVID-19
118720533 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
118720533 (PLCG2)
05169 Epstein-Barr virus infection
118720533 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
118720533 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
118720533 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pkl04131
]
118720533 (PLCG2)
Enzymes [BR:
pkl01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
118720533 (PLCG2)
Membrane trafficking [BR:
pkl04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
118720533 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
118720533 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
SH3_9
PH
EF-hand_PLCG1
PH_12
SH2_1
SH3_2
PH_14
Adhesin_E
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
118720533
NCBI-ProteinID:
XP_036296469
LinkDB
All DBs
Position
Unknown
AA seq
1264 aa
AA seq
DB search
MTTMVNVDALPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRQKEDCCFTILYGTQFVLSTLSLATDSKEDAT
KWLSGLKILHQEAMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKAILPLVNFKVSSA
KFLKDKFAEIGAHKDEFSFEQFHLLYKKLMFEQQKSILDEFKKDSSVFILGTDRPDASAV
HLHDFQRFLLHEQQELWAQDVNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSI
WDEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCW
DGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCVEQQRYMARVF
KEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGEL
YMWDPIDLKWTRHYCAIADAKLSFSDDIEQSVEEEPPQDTPPTELHFGEKWFHKKVEKRT
SAEKLLQEYCSETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGTMKYYL
TDNLMFTSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDMLM
RVPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYE
KHALYRKMKLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYK
AKQSDELSFCRGALIHNVSKEPGGWWKGDYGTKIQHYFPSNYVEDISTVDVEELEKQIIE
DNPLGSLCKGILDLNTYNVVKAPHGKNQKPFVFILEPKKQGDPPVEFATDRVEELFEWFQ
SIRQITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVET
KADSVVRQKPIELLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTGDKYM
QMNQALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKIQMTLTVKVLGARHLPKLGRSIA
CPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWASTQEKVTFEIYDPNLAFLRFVVYEEDM
FSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLECEEELYSSCR
QLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLHLYQEKCNRRLREKRVSNS
KFYS
NT seq
3795 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccatggtcaacgtggacgcccttccggaatatgagaagagtcagatcaagaga
gccctggagctgggcaccgtgatgactgtgttcagcttccgcaagtccaccccggagcgc
aggaccgtccaggtgatcatggagacgcggcaggtggcgtggagtaagacggccgacaag
atcgagggcttcctggatatcatggagatcaaggaaatccgcccagggaagaactccaag
gactttgagcgtgcgaaggcagtccgccagaaggaagactgctgcttcaccatcctgtat
ggcacccagttcgtcctcagcacactcagcttagcaactgattcgaaggaagacgcaacc
aagtggctctccggcttgaagatcttacaccaagaagcgatgagcgcatccacccccacc
atcattgagagttggctgagaaagcagatttattcggtggatcaaaccagaagaaacagc
atcagcctccgagagttgaaggccatcttgcccctggtcaacttcaaagtgagcagtgcc
aagttcctcaaggataagtttgcggaaataggtgcccacaaagatgaattcagctttgaa
cagttccatctcctctataaaaaacttatgtttgagcagcaaaaatcgattcttgacgag
ttcaaaaaggattcctccgtgttcatcctgggtaccgaccggcccgatgcctctgcggtc
cacctgcatgacttccagcggtttctcttacatgaacagcaggaactttgggctcaggat
gtgaacaaagtccgtgagaggatgacaaagtttatcgacgacacgatgagagaaacggca
gagcccttcttgtttgtggatgagttcctcacgtacctgttttcacgggagaacagcatt
tgggatgagaagtatgacgtggtggacatgcaagacatgaacaaccccttgtctcactac
tggatctcctcgtcacataacacgtacctcacaggtgaccagctgcggagtgagtcatcc
ccggaggcatatatccgctgcctgcgcatgggctgtcgctgcattgagttggactgctgg
gacgggcccgacgggaagcccatcatctaccacggctggacccggaccaccaagatcaag
ttcgatgacgttgtgcaggccatcaaagaccacgcctttgtcacctcaagcttccccgtg
atcctgtccatcgaggaacactgttgcgtggagcagcagcgctacatggccagagtattc
aaggaggtgtttggcgacctgctgctgaccaagcccacggaggccagcgcggaccagctg
ccctcgcccagccagctgcgggagaagattatcatcaagcataagaagctgggcccccga
ggcgacgtagatgtcaacatggaggacaagaaagatgagcacaagcagcagggggagctg
tacatgtgggatcccatcgacctgaaatggactcggcactattgcgccattgccgatgcc
aagctgtccttcagcgacgacattgagcagagtgtggaagaggaaccgccccaggacacg
ccccccacagagctgcattttggagagaagtggttccacaagaaggtggagaagaggaca
agtgccgagaagctgttgcaggaatactgctctgagacggggggcaaggatggaaccttc
ctggtgcgggaaagcgagaccttccccaacgactacaccctgtccttctggcggtctggc
cgggtccagcactgccggatccgctccaccatggagggcgggaccatgaagtactacctg
actgacaacctcatgttcaccagcatctacgccctcatccagcactaccgcgagacgcac
ctgcgctgcgccgagtttgagctccgcctcacggaccccgtgcccaaccccaacccccac
gaatcaaagccgtggtactacgacggactgagccgtggagaagcggaggacatgctgatg
agagttccccgggatggcgccttcctcatccggaagcgggaaggtagcgactcctacgcc
atcaccttcagggcccggggcaaggtgaagcactgtcgcatcaaccgggatggccggcac
ttcgtgctggggacctctgcctacttcgagagcctggtggagctcgtcagctactacgag
aagcacgcgctctaccggaagatgaagctgcgctaccccgtgacccccgagctcctggag
cgctacaacatggaaagagatataaactccctgtatgacgtcagcagaatgtatgtggat
cccagtgaaatcaatccttctatgcctcagagaaccgtgaaagctctgtatgactacaaa
gccaagcagagtgacgagctgagcttctgccgtggtgccctcattcacaacgtctccaag
gagcccgggggctggtggaaaggcgactatggaaccaaaatccagcactacttcccgtcc
aattacgtcgaggacatttcaacggttgatgtggaggagctcgagaagcagattattgaa
gacaatcccttagggtctctttgcaaaggaatattggatctcaacacctataatgttgtg
aaagccccgcacgggaagaaccagaaacctttcgtctttatcctggagcccaagaagcag
ggtgaccccccagtggagtttgccacggaccgggtggaggagctcttcgagtggttccag
agcatccggcaaatcacctggaagatcgacaccaaggagaacaacatgaaatactgggag
aagaaccagtcgatcgccatcgagctctcggacctggtcgtctactgcaaaccaaccagc
aagaccaaagacaacttagaaaatcccgacttccgagaaatccgttcctttgtggagacg
aaggccgacagcgtcgtcagacagaaacccatcgagctcctgaagtacaaccagaagggc
ctgacccgtgtttacccgaagggacagagggtggactcctccaactacgaccccttccgc
ctctggctgtgcggctcccaaatggtggcactcaacttccagactggagacaaatacatg
cagatgaaccaggccttgttttcactcaatgggaggaccggctacgtcctgcaacccgag
agcatgagaacggagaagtacgaccccatgccgcccgagtcccagcggaagattcagatg
accttgacagtcaaggttctcggggctcgccatctccccaagctcggacgaagcattgca
tgtccctttgtggaggtggagatatgcggagccgaatatgacaacaacaagtttaagaca
acggttgtgaatgacaatggcctaagccctgtgtgggcttccacgcaggagaaggtgaca
ttcgaaatttacgacccgaacctggcattcctgcgctttgtggtgtacgaggaagacatg
ttcagcgaccccaactttctcgcgcatgctacttaccccattaaaggaatcaagtcagga
tttagatctgttcctttgaagaacgggtacagtgaagacattgagctggcttccctcctg
gttttctgtgagatgcggccggtgctggaatgtgaagaggaactgtactcttcctgtcgc
cagctgcggaggcggcaagaagagctgaacaaccaactcttcctatatgacacacaccag
aacttgcgcaatgccaaccgggatgccctcgttaaagagttcaatgtcaacgagaaccag
ctccatctgtaccaggagaagtgcaaccggaggttaagagagaagagggtcagcaacagc
aagttttactcatag
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integrated database retrieval system
