KEGG   Pipistrellus kuhlii (Kuhl's pipistrelle): 118731187
Entry
118731187         CDS       T07682                                 
Symbol
PRKACA
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit alpha isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
pkl  Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl01522  Endocrine resistance
pkl04010  MAPK signaling pathway
pkl04014  Ras signaling pathway
pkl04020  Calcium signaling pathway
pkl04024  cAMP signaling pathway
pkl04062  Chemokine signaling pathway
pkl04081  Hormone signaling
pkl04082  Neuroactive ligand signaling
pkl04114  Oocyte meiosis
pkl04140  Autophagy - animal
pkl04211  Longevity regulating pathway
pkl04213  Longevity regulating pathway - multiple species
pkl04261  Adrenergic signaling in cardiomyocytes
pkl04270  Vascular smooth muscle contraction
pkl04310  Wnt signaling pathway
pkl04340  Hedgehog signaling pathway
pkl04371  Apelin signaling pathway
pkl04530  Tight junction
pkl04540  Gap junction
pkl04611  Platelet activation
pkl04713  Circadian entrainment
pkl04714  Thermogenesis
pkl04720  Long-term potentiation
pkl04723  Retrograde endocannabinoid signaling
pkl04724  Glutamatergic synapse
pkl04725  Cholinergic synapse
pkl04726  Serotonergic synapse
pkl04727  GABAergic synapse
pkl04728  Dopaminergic synapse
pkl04740  Olfactory transduction
pkl04742  Taste transduction
pkl04750  Inflammatory mediator regulation of TRP channels
pkl04910  Insulin signaling pathway
pkl04911  Insulin secretion
pkl04912  GnRH signaling pathway
pkl04913  Ovarian steroidogenesis
pkl04914  Progesterone-mediated oocyte maturation
pkl04915  Estrogen signaling pathway
pkl04916  Melanogenesis
pkl04918  Thyroid hormone synthesis
pkl04919  Thyroid hormone signaling pathway
pkl04921  Oxytocin signaling pathway
pkl04922  Glucagon signaling pathway
pkl04923  Regulation of lipolysis in adipocytes
pkl04924  Renin secretion
pkl04925  Aldosterone synthesis and secretion
pkl04926  Relaxin signaling pathway
pkl04927  Cortisol synthesis and secretion
pkl04928  Parathyroid hormone synthesis, secretion and action
pkl04934  Cushing syndrome
pkl04935  Growth hormone synthesis, secretion and action
pkl04961  Endocrine and other factor-regulated calcium reabsorption
pkl04962  Vasopressin-regulated water reabsorption
pkl04970  Salivary secretion
pkl04971  Gastric acid secretion
pkl04976  Bile secretion
pkl05012  Parkinson disease
pkl05020  Prion disease
pkl05030  Cocaine addiction
pkl05031  Amphetamine addiction
pkl05032  Morphine addiction
pkl05034  Alcoholism
pkl05146  Amoebiasis
pkl05163  Human cytomegalovirus infection
pkl05165  Human papillomavirus infection
pkl05166  Human T-cell leukemia virus 1 infection
pkl05200  Pathways in cancer
pkl05203  Viral carcinogenesis
pkl05205  Proteoglycans in cancer
pkl05207  Chemical carcinogenesis - receptor activation
pkl05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pkl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118731187 (PRKACA)
   04014 Ras signaling pathway
    118731187 (PRKACA)
   04310 Wnt signaling pathway
    118731187 (PRKACA)
   04340 Hedgehog signaling pathway
    118731187 (PRKACA)
   04371 Apelin signaling pathway
    118731187 (PRKACA)
   04020 Calcium signaling pathway
    118731187 (PRKACA)
   04024 cAMP signaling pathway
    118731187 (PRKACA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    118731187 (PRKACA)
   04081 Hormone signaling
    118731187 (PRKACA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    118731187 (PRKACA)
  09143 Cell growth and death
   04114 Oocyte meiosis
    118731187 (PRKACA)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    118731187 (PRKACA)
   04540 Gap junction
    118731187 (PRKACA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118731187 (PRKACA)
   04062 Chemokine signaling pathway
    118731187 (PRKACA)
  09152 Endocrine system
   04911 Insulin secretion
    118731187 (PRKACA)
   04910 Insulin signaling pathway
    118731187 (PRKACA)
   04922 Glucagon signaling pathway
    118731187 (PRKACA)
   04923 Regulation of lipolysis in adipocytes
    118731187 (PRKACA)
   04912 GnRH signaling pathway
    118731187 (PRKACA)
   04913 Ovarian steroidogenesis
    118731187 (PRKACA)
   04915 Estrogen signaling pathway
    118731187 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    118731187 (PRKACA)
   04921 Oxytocin signaling pathway
    118731187 (PRKACA)
   04926 Relaxin signaling pathway
    118731187 (PRKACA)
   04935 Growth hormone synthesis, secretion and action
    118731187 (PRKACA)
   04918 Thyroid hormone synthesis
    118731187 (PRKACA)
   04919 Thyroid hormone signaling pathway
    118731187 (PRKACA)
   04928 Parathyroid hormone synthesis, secretion and action
    118731187 (PRKACA)
   04916 Melanogenesis
    118731187 (PRKACA)
   04924 Renin secretion
    118731187 (PRKACA)
   04925 Aldosterone synthesis and secretion
    118731187 (PRKACA)
   04927 Cortisol synthesis and secretion
    118731187 (PRKACA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    118731187 (PRKACA)
   04270 Vascular smooth muscle contraction
    118731187 (PRKACA)
  09154 Digestive system
   04970 Salivary secretion
    118731187 (PRKACA)
   04971 Gastric acid secretion
    118731187 (PRKACA)
   04976 Bile secretion
    118731187 (PRKACA)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    118731187 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    118731187 (PRKACA)
  09156 Nervous system
   04724 Glutamatergic synapse
    118731187 (PRKACA)
   04727 GABAergic synapse
    118731187 (PRKACA)
   04725 Cholinergic synapse
    118731187 (PRKACA)
   04728 Dopaminergic synapse
    118731187 (PRKACA)
   04726 Serotonergic synapse
    118731187 (PRKACA)
   04720 Long-term potentiation
    118731187 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    118731187 (PRKACA)
  09157 Sensory system
   04740 Olfactory transduction
    118731187 (PRKACA)
   04742 Taste transduction
    118731187 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    118731187 (PRKACA)
  09149 Aging
   04211 Longevity regulating pathway
    118731187 (PRKACA)
   04213 Longevity regulating pathway - multiple species
    118731187 (PRKACA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    118731187 (PRKACA)
   04714 Thermogenesis
    118731187 (PRKACA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118731187 (PRKACA)
   05205 Proteoglycans in cancer
    118731187 (PRKACA)
   05207 Chemical carcinogenesis - receptor activation
    118731187 (PRKACA)
   05203 Viral carcinogenesis
    118731187 (PRKACA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118731187 (PRKACA)
   05163 Human cytomegalovirus infection
    118731187 (PRKACA)
   05165 Human papillomavirus infection
    118731187 (PRKACA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    118731187 (PRKACA)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    118731187 (PRKACA)
   05020 Prion disease
    118731187 (PRKACA)
  09165 Substance dependence
   05030 Cocaine addiction
    118731187 (PRKACA)
   05031 Amphetamine addiction
    118731187 (PRKACA)
   05032 Morphine addiction
    118731187 (PRKACA)
   05034 Alcoholism
    118731187 (PRKACA)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    118731187 (PRKACA)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    118731187 (PRKACA)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    118731187 (PRKACA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pkl01001]
    118731187 (PRKACA)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:pkl03019]
    118731187 (PRKACA)
   03036 Chromosome and associated proteins [BR:pkl03036]
    118731187 (PRKACA)
Enzymes [BR:pkl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     118731187 (PRKACA)
Protein kinases [BR:pkl01001]
 Serine/threonine kinases: AGC group
  PKA family
   118731187 (PRKACA)
Messenger RNA biogenesis [BR:pkl03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     118731187 (PRKACA)
Chromosome and associated proteins [BR:pkl03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    118731187 (PRKACA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 118731187
NCBI-ProteinID: XP_036315424
LinkDB
Position
Unknown
AA seq 351 aa
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPDQNTANLDQFERIKTLGTGSFGRVML
VKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCAKEFSDF
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgggcaacgccgccgccgccaagaagggcagcgagcaggagagtgtgaaagagttctta
gccaaagccaaagaagatttccttaaaaaatgggaaagtcctgatcagaacacagccaat
ttggatcagtttgaacggatcaagaccctcggcacaggctccttcgggcgggtgatgctg
gtgaaacacaaggagactgggaaccacttcgccatgaagatcctggacaaacaaaaggtg
gtgaagctgaaacagatcgagcacaccctgaatgagaagcgcatcctgcaggctgtcaac
tttccgttcctcgtcaagcttgagttttccttcaaggataactcgaatttgtacatggtc
atggagtacgtgcccggcggggaaatgttctcacacctgcggcggatcggaaggttcagc
gagccccacgcccgcttctacgctgcccagatcgtcctgaccttcgagtacctgcactcg
ctcgatctcatctaccgggacctgaagccagagaaccttctcatcgaccagcagggctac
attcaggtgacagactttggttttgccaagcgtgtgaaaggccgcacctggaccttgtgc
gggacccccgagtacctggcccccgagatcatcctaagcaaaggctacaacaaggccgtg
gactggtgggccctgggggttctcatctacgagatggctgctggctacccccccttcttc
gctgaccagcccattcagatctacgagaagattgtttctgggaaggtgcggttcccatcc
cacttcagctctgatttgaaggacctgctgcggaacctccttcaggtggaccttaccaag
cgctttgggaacctcaagaacggggtcaatgacatcaagaaccacaagtggttcgccacg
actgactggattgccatctaccagaggaaggtggaagctcccttcataccaaagtttaaa
ggccctggggacacgagtaattttgatgactacgaagaggaagaaatccgagtctccatc
aatgagaagtgtgcaaaggagttttctgatttttag

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