Pipistrellus kuhlii (Kuhl's pipistrelle): 118731195
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Entry
118731195 CDS
T07682
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
pkl
Pipistrellus kuhlii (Kuhl's pipistrelle)
Pathway
pkl04217
Necroptosis
pkl04380
Osteoclast differentiation
pkl04620
Toll-like receptor signaling pathway
pkl04621
NOD-like receptor signaling pathway
pkl04630
JAK-STAT signaling pathway
pkl04658
Th1 and Th2 cell differentiation
pkl04659
Th17 cell differentiation
pkl05145
Toxoplasmosis
pkl05160
Hepatitis C
pkl05161
Hepatitis B
pkl05162
Measles
pkl05164
Influenza A
pkl05165
Human papillomavirus infection
pkl05167
Kaposi sarcoma-associated herpesvirus infection
pkl05168
Herpes simplex virus 1 infection
pkl05169
Epstein-Barr virus infection
pkl05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pkl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
118731195 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
118731195 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
118731195 (TYK2)
04621 NOD-like receptor signaling pathway
118731195 (TYK2)
04658 Th1 and Th2 cell differentiation
118731195 (TYK2)
04659 Th17 cell differentiation
118731195 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
118731195 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
118731195 (TYK2)
05160 Hepatitis C
118731195 (TYK2)
05171 Coronavirus disease - COVID-19
118731195 (TYK2)
05164 Influenza A
118731195 (TYK2)
05162 Measles
118731195 (TYK2)
05168 Herpes simplex virus 1 infection
118731195 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
118731195 (TYK2)
05169 Epstein-Barr virus infection
118731195 (TYK2)
05165 Human papillomavirus infection
118731195 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
118731195 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pkl01001
]
118731195 (TYK2)
Enzymes [BR:
pkl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
118731195 (TYK2)
Protein kinases [BR:
pkl01001
]
Non-receptor tyrosine kinases
JAK family [OT]
118731195 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
FERM_C_FAK1
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
118731195
NCBI-ProteinID:
XP_036315438
LinkDB
All DBs
Position
Unknown
AA seq
1192 aa
AA seq
DB search
MPRRHGGATARASKPDGGEAQLTAITGGLKVFLHWAGPGSREPWVTFSEATLTAEEVCIH
IAQKIGITPPCFNLFALFDAQAQVWLPPNHILEVSRDTNLTLHFRMRFYFRNWHGTNPQE
PAVYRCRPPGAEASSEQAEQGIQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIRHF
KNESLGMAFLHLCHLALCRGVPLEKVAKKTSFKDCIPRSLRQQIRQYNAFTQLRLRIIFR
RFLHAFQPGSLSQQVVMVKYLATLERLAPRFGAERVPVRRLELLAQAEGEPCYVQDGAQA
PGDPKPKPAVEPPTHEVLVTGTGGIQWRPVQTEARGFQSPSGGDGGRGRTSQSGSAGRKA
KAQPLGGQPVDGPREAPWAFFCDFQDITHVVLRECHVSIHCQDKRLELTLPSPAAALSLV
SLVDGYFRLTADSNHYLCHEVAPPRLVTSIQDGVHGPLLDPFVLAKMQREDGLYLIHWST
SHFHRLLLTVAQRDQAPGTQGLRLWKFPIELREGTFRLQSWDRSFPSVRELRAALQGCSL
RAGDHCFALRHCCLPQPGEISNLIIMRGPQASTRSLNLSQLSFHRVCQEDLTQLSHLGQG
TRTNVYEGLLRVGGGGPEEDKADAGDPTLPGGGRGQELRVVLKVLDPSHHDIALVSACDG
GREGGRVCGHLPCPALPGFLRDGQPHEPGVPRAPDLRPRSLRAWLQKYHGDRVRGAWTPG
RVAAAGEGPCACGLEGGSGPAAGQCPQLPGGQAPGPWKRVWPEHPAGTSGAGGGHQPVHQ
TERPWHGPGRPLQGGLSTAADKWGFGATLLEICFDGEAPLQDRGPSEKEYFYQKQHPLAE
PSCPELATLTSQCLTYEPAQRPSFRTILRDLTHLQPQNLVEILSVTPTSPASDPTVFHKR
YLKKIRDLGEGHFGKVSLYCYDPTNEGTGEMVAVKALRADCGPQLHTGWRREIDILRTLY
HEHIVKYKGCCEDRGEKSVQLVMEYVPLGSLRDYLPRHHVGLAQLLLFAQQICEGMAYLH
TQHYVHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGYEYYRVREDGDSPVFWYAPECLKE
CKFYYASDVWSFGVTMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLP
RPEKCPHEIYVLMKNCWEAEASFRPTFQNLIPILKTVHEKYQGQAPSVFSVG
NT seq
3579 nt
NT seq
+upstream
nt +downstream
nt
atgcctcggcgccatgggggggccaccgccagggccagcaagccggatgggggcgaagct
cagctcacggccatcacgggaggcctgaaggtgttcctgcactgggcaggccctggcagc
agggagccctgggtcactttcagcgaggccaccctgaccgcagaggaggtctgcattcac
atcgcacaaaaaatcggcatcactccaccctgtttcaatctctttgccctctttgatgcc
caggcccaggtctggctgcccccaaaccacattctcgaggtctccagagacacaaacttg
acgctgcacttccgcatgaggttttacttccggaactggcatggcacaaaccctcaggag
ccagctgtgtatcgctgcaggcccccaggggccgaggcctcgtcagaacaggcagagcag
gggatacagctcctggaccccgcctcctttgagtacctctttgagcagggcaagcatgag
tttgtgaatgatgtggcatcgctgtgggagctgtcgagtgaggaggagatccgccacttt
aagaacgagagcctgggcatggcctttctgcacctctgtcaccttgctctctgccgcggt
gttcccctggagaaggtggccaagaagaccagcttcaaggactgtatcccgcgctctctc
cggcagcagatccggcagtacaacgcgttcacccagctccgcctgcggatcatcttccgc
aggttcctgcacgccttccagccgggcagcctttcccagcaggtcgtcatggtcaagtac
ctggccaccctggagcggctggcgccccgcttcggtgcggagcgtgtgcctgtgcgccgc
ctcgagctgctggcccaggccgagggggagccctgctacgtccaggacggtgcacaggcc
cccggagaccccaagcccaagcctgcggtcgaaccgcccacccacgaggtgctggtgact
ggcactggcggcatccagtggcggccagtgcagacagaggcgcggggtttccagagtccc
agcggtggtgacggtggccgaggcaggacttcccaatccggctccgctgggaggaaagcc
aaggcccagccgctgggcggccagcctgtggacgggccgcgggaggcgccgtgggccttc
ttctgtgacttccaggacatcacccacgtggtgctgagagagtgccacgtcagcatccac
tgtcaggacaagcgcctggagctgaccctgccttccccggccgccgccctgtccctggtg
tcgctggtggatggctatttccgcctgacggctgactcgaaccactacctgtgccacgag
gtggcgcctccacggctggtgacgagtatccaggacggtgtccacggacccctgctggat
ccctttgtgctggccaagatgcagcgggaggacggcctctatcttatccactggagcacc
agccacttccaccgcctcctcctcacggtggcccagcgggaccaggcccccggcacgcag
ggtctgcgcctgtggaagttccccatcgagctgcgtgagggcaccttcaggctgcagagc
tgggaccggtccttccccagcgtgcgggagctgcgggccgccctgcagggctgctccctg
cgggccggtgaccactgcttcgccctgcgccactgctgcctgccgcagccgggagagatc
tccaacctcatcatcatgcgcggacctcaggccagcaccaggtctctcaacctcagccag
ctcagcttccaccgggtctgccaggaggacctcacccagctgtcccacttgggccagggc
acgaggaccaatgtgtacgagggcctcttgagagttgggggcggaggccccgaggaggac
aaagcggatgctggggaccccaccttgcccggcgggggccgtgggcaggagctgcgagtg
gtgctgaaggtgttagacccgagtcaccatgacatcgccctggtaagtgcgtgtgacggg
ggcagggagggcggcagggtctgcggccacctgccctgccctgccctcccaggctttcta
cgagacggccagcctcatgagccaggtgtcccacgtgcacctgaccttcgtccacggagt
ctgcgtgcatggctccaaaaatatcatggtgacagagtacgtggagcatggacccctgga
cgtgtggctgcggcgggagaggggccgtgtgcctgtggcctggaaggtggcagtggccca
gcagctggccagtgccctcagctacctggaggacaagcgcctggcccatggaaacgtgtg
tggccggaacatcctgctggcacgtctggggctggcggagggcaccagcccgttcatcaa
actgagcgaccctggcatgggcctgggcgccctctccagggaggcctgagcaccgccgct
gacaagtggggctttggcgccacgctcctggagatctgcttcgatggggaggcccccctg
caggaccgcggcccctccgagaaagagtacttctaccagaagcagcacccgctggccgag
ccctcgtgcccggagctagccacactcaccagccagtgcctgacctatgagcccgctcag
cggccctccttccgcaccatccttcgcgacctcactcaccttcagccccaaaatcttgtt
gaaatcttgtctgtgactccaacctcaccagcatcagaccccactgttttccacaagcgg
tacttgaaaaagatccgggatctgggtgagggtcacttcggcaaagtcagcctgtactgc
tacgacccgaccaacgagggcaccggcgagatggtggccgtgaaggccctcagggcggac
tgcggccctcagctccacaccggctggaggcgggagatcgacatcctgcgcaccctctac
cacgagcacatcgtcaagtacaagggctgctgtgaggaccgaggggagaaatcggtccag
ctcgtcatggagtacgtgcctctgggcagcctccgagactacctgccccggcaccacgtc
ggcctggcccagctgctgctgttcgcccagcagatctgcgagggcatggcctacctgcac
acccagcactacgtccaccgagacctggctgcccgcaacgtgctgctggacaacgaccgg
ctggtcaagatcggggacttcggcctggccaaggccgtgcccgagggctacgagtactac
cgagtgcgcgaggatggcgacagccccgtgttctggtacgcccctgagtgcctgaaggag
tgcaagttctactatgcgtctgacgtctggtcctttggagtcaccatgtatgagctgctg
acctactgtgactccagccaaagcccgccctcgaaattcatcgagctcatcggcctcacg
cagggccagatgacagtactgaggctcacggagctgctggaacgaggggagaggctgcca
cggccagagaaatgtccccatgagatctacgtcctcatgaagaactgctgggaggcagag
gcctcgtttcgcccgaccttccagaacctcatacccatcctgaaaaccgtccacgagaag
taccagggccaggccccctccgtgttcagtgtcggctaa
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integrated database retrieval system
