Pempheris klunzingeri: 139211858 Help Entry 139211858         CDS       T11454                                  Symbol syne1b Name (RefSeq) nesprin-1   KO K19326   nesprin-1 Organism pklu  Pempheris klunzingeri Pathway pklu04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:pklu00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     139211858 (syne1b)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:pklu03036]     139211858 (syne1b) Chromosome and associated proteins [BR:pklu03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     139211858 (syne1b) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 CH SYNE1 KASH Spectrin_SYNE1_2 SYNE3 ATG17_like Motif Other DBs NCBI-GeneID:  139211858 NCBI-ProteinID:  XP_070698376 LinkDB All DBs Position 13:19229058..19307104 Genome browser AA seq 8793 aa AA seqDB search MASPRQFGRSSVDIANVMQKLQDEQEAVQKRTFTKWINSHLAKYKPPLEVNDLFEDIKDG VKLLALLEVLSGQRLPREQGRQLKRIHWVSNIGTALKFLEGRKSVYRGSPIKLVNIHATD IADGRPSIVLGLIWTIILYFQIEELTSNLPALQALSNSNSSVESIASSETGSPPMKRKVV NKFQGNAKKALLRWVQCTAAKYHGIEVKDFGPSWRDGVAFQSVVHAIRPDLVDMEVVQRR SNRENLEDAFALAENELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPNPHSETDGQQ DEFGPQDIEQMLEREERKMLRELKVFLDQLERDVLRAQGAEGNLTDKYQAFKSFRVQYEM KKKQTDPLLQPVHRDGKLSVDQALVKQAWDRVSARLLDWHIHLDKSLPGPLGVIGAWLHR AEMALREDIPIQHAHEETANVLHRKLEQHKEVLKNLESHRQTFQQIHRDRSVNGVPVPPE QLQDMAERFNFVSTSSYAHLIKLEFWEIKYRLMAFLVLAESKLKSWIIKYGRRDSVELLL QTYLTFVEGHRFFEQYEIIYTNLKQAAEVYVKSDSSRSKTCNKVDEAEGVSKFLSDATAQ WKNLALEVRSVRSMLEEVISNWEKYSSTVAALQAWLEDAEQMLNHSENAKRDFFRNLSHW MQQHTDMNDAGNFLIETCDDTVSRDLKQQLLLLNGRWRELFVKVKHYARADEVDKLRQDY QDGINTLKMFMDATNEKMTAPVQVSFLNVRAFAQDVEDIKHKVPAMEAACKAACRTAQLL TKDTPQEEVSQMMAVMASIKEQLSKVRERCLPLLRESQSLLPPLEEMEKNITGFYQALEK ASHITSTTDSEGPVDFKQKCQELATFTHSCKKCLTSIERNHQTIQKIMSSSKTLEHMDMS LLQKRVGDLQSSSQAMIKESTEWRKHVEANSSLMKRFDESRVELEKVLKMAQNCLTERGN PEELLKKHTEFFGQLDQRVLNTFLKACDELTDILPEQEQQSLQETVRKLHKHWKDIQTDA PFHLLHLKVEVERSKLMALLQECQAEVTRENRHLASIGSERLIKEHRAFFREKGPQSICE KRLQLMEELCQKLPEGDPVHQILETAKKDFSEVREEIESTHQKLMQHPDKWKEYNARYAE LSCWLISKESQLRLLRNRANDPRKYGQVKSSIMELRNDAELQEGNLGWLKARVAVLIEIC ADSDGQRQGSALSKLSTDFKGLLASLSEAEKMVLAVGDCVQFREEVQATLGDLIQGQKDA QTEVTKILDSPTVREAQQLHLVHQQLLKRLKLKRKDVQQLITRGQQLQAEEGLGETLQQD LQSLENTLSKMEQNMDSQEQSLEVTLAAWQEFDSQQEAVCEFVNKARSTMDRDLNFSSPE SLAVELDQARVLLKQCEAEASHMNILLKRATEIQLGPKNKTLLLQQGRSLSEQVDKVEAG LKKDVKTLEEMKSQWDQFGGGFETFSLWISDKEKQLDVLKSSTLPLEQQINTVKAICAEL QERAEVPSQLEAESQALAQFVSSGEAARIKARLTQIGRYWEELKESVQQVDGQLEESSSH QQKFKISLEEVQASLSELHIKLEHPIKSCTSSSETYKALQNHMDVCQQLEKLKGTLLSLL AGARRLSDKEQAERTVTELNTSYHQNIQEAKDKQNTLENLLSLWQKYEKHRSNFVSYLER SESASKLDSQCLAADKTKLRTELQDLQALYSEVRTLEPAHAELVSLGMSLYPSAPEERVK QLKDELETLQRRLHVQNEVLPQRIKELQSHLSQVEQFDQALIKFSQWSETMLSNLHSASQ INISNLQSAATKVKETQVALQKHSSVRQSLEQQTEKLCQFCEPGDAQLLRSRAESCLQPY LESQHIAELQLECFERLEAFLQTHGVAAGVLRGLRQTVESAGSWDRGKVEELQQELATIV PDITQLETLAVNLDSGLCKSHLHIGADEGSRKSCRMLADSLSAELDAVRNLLGTKQSEAE ALGALWTSFRQRKEQLLKAVEDIEEKADHQSFKEPSLHALQQRLRFFNQMEDELQSHQHE EQWLRDKGNQLAQRDAELAGEVLREISLLETTWEDTKRLITERQEQCNVLVELMREYQTL KTSISSIIESTETLVEISAVMKDHEETRRCLTKHEAVKIEMASKQHELDQFSSKGKQLVI ELKKIPECDAQMMKKDMETLVDQWLDVSEKIDDNIDHLNQSLALWDDVRKISEDIESWTS SCVIELNESLNNLNDSQKVSARLSVLQVEMGEKEQKLETLQNRVSELKKCSQSQETPAKL QVLDNDLRKKISSVQKLHEQARGNLMDFTSQRKQLEDYISQMSAWLKSMEDSLVSSPTGT DPEDICRVKDLQKELQNQQGSIDSTRESLNTLCRKYPSEELAGLGSALTDLIKIYESVNQ LSARTLVSLQNCLQQQFNDLVQEFHRWLSEQREIVKECSDRSGDTQIVERKLQKLKGAMD RVEEGEVRLTQVCEEGEKLLLHLPKASAGQIQQHLSSIQQDWDSFVEQCRQNQQILEDSA SLMKGFEGRLKKLRWWLEHMEKRMTTDLLEAKQRGPEKAVLEQVEEYQQEVLKERDSFER LCQEGQALNEGGRGDGSETRVSAQLQSQHQALLRRVRERLRSCQLTLQEQQAFEETLQTT WGWLNGVQERLASLNSTIGNKETLEKRLGLVQDILLMKGEGEVKLNMTMGKGEQVLKHNR MEGQEAICSQLQSLKDAWANMLMTSMSCHSRLEWTVAQWTSFQESKGQLQQWMESVEQEV GMSLPQQPGLKEKSALLERLRAIQADVDAHAAALSRLTDKAVEMHEKTADQTFGPESRAE LNAHFADISAVVKGKVQSMQNIVSEHEQYLDALRDFNDWLISAKEELQRWSDLSGDSVSI KRKLSKVQELLDSKQRGRERLNRVQRCGAVARDHTGSGGYEAMEREEAALLSSWEQWERG ALQTRASLETALSQITSSEQEFNSRSAQLEHDLRDFSRQLHDWRLRLAQAARKTDGEEAV KCWQIAKDTVEELIKAEPMSDSLKTQLNDLYRFSRDMGTQSERVSALIKEYNSLSLQASR ECQSKEKILDQGFRSVFREFQQWLVNAKINTAKCFDVPQNVNEASSSLQKIQEFLNDREH GQSKLNAVVVNGELVSSVAAKDKADAVRAKMNTAREDWKNMMSNLHNRETSLQNLLSQMK DFEASAEPLHECLNATELAVQESSTRLHDLTAKKQELHKLQSVLEELASHEIQLNRLKEK AQLLWDEQAAGKGFVHRVSQLSAQYLALTNLTKEKASRIDRIVTEHQLFSQGLNELQNWV ADTSHMLQTYCAPTADKNVLDSRMIKLEALLTARQEKEIQLKMLITRGESVQRNTSADGV PAVQKQIQDLKDSWDALLSTSIQCKSQLEGSLSQWTSYQEDVRQFVAWVERVEESLDPTD KQCPEMRDKTANLSKAKLLHEEVLSHNTLLDTITAKSAGIAENFVTQLELQDLQERYKTI KDNAMRAVGKAEELVKAHQEYQRGLHAFEDWLEQEQEKLSCYTQLEGDVDMLEETLQKLQ ELQLHCTEGQALLNTLLVSRELVIPWGLPQIEDRALETLQQEWRLYQGRLADTRAQLNSA LAKLRQMEQKFQRLDSWLKAMETKAQLRGHRRSDRTTKDAQLQLLKSWQEEVLVYQEEME GLSLLAQQVLDETHISSQISSRATKITARYHVLLLHLLETIKQLQEEVSCIEEAQCVFGT FSDWLSTAQNNFSSVAISVDAVDRFAMERKMKKLEALQADMEQGHTYLKTMREKTERSMA FLEEPEAEQLKEEVDMRLFQLQELMEALRMEHSSLEKCISLSKDFMDKYKAQAQWVTETK NLLASSVEPKAELYQKKAQLAKYKTIQQTVQSHEPALKSVFEKGEALLDIVHDATISDNM KKLQADYQDLCLATKTQVQNLIEWVREHEDYNSELQEVEKWLLQMSSRLVTSDSMQTSGM EMATQQLARHKAIMEEIASFEERLTSLKQKGEDLVASCTDQVQAKICQQVQAHQQGTRDS YSAICSTAQRVYQSLDRELQKHVNHQDTLQQCQTWLTTVQEELQLNDQGPSGLQDALKQV KHYRALQEQASTYLDLVCSVCDLSDDAVRVAAAQVQQIKLTIEERMSSAQELSEGWREIK EQKQDLTSLFQDMEQQLLSFSRRPAELETKIAQNMLSQAKECSQQLQSKQSILTKMTETV SRLTGGQDSSEHAELDRLSHSWLELCHQASKLQSQREEDLQRSKEYHDCITAVEVLFEQV SKEWDNLARTDAESSSQHLEALRKLAVTLEEQKGTLEELKEQKQKVIQHLNLDDKELVKE QISHFEQRWSQMQNLIERKIQDSVVTLDDMGQVEARLREARDWAEEQQPALSEAMKMSPP PELAQSFLFDHLSICSELEAKQLLLAQAMTDADRVLARLGLSERQRLQQLIADTQQEVES LSVKVVQRRKHLSKAFTERTQFLMAVNQSISWVQQNEKKAQAEEYIALLPDDLAKQVRTC RNIQSSLKAYQSELTSLWSQGRDLMRDASEEERNEILTKLQELQNIFDKTLHRCGQKLQE LEKVLVSRKYFKTDLEKICLWIKQADIVTFPEINLMVGDAELEVQLLKYQHIVEQAIEYE NLLLIVQRAGQEILPSLNEVDHCYLDEKLNVLPQQYNSILALAKEKQEKIQQAILTRNEY TSFIDVTHKALKELEEQFNNLGTQPVGLQTEEVVSLQSDYKRIQADLSNLGLAVSELNQK KEGFRSTGQPWRPEEMTQLVSLYNGLRRLVEQKVEHLDETLESFEDHKAMAMQVDSELKA TKEQLVKVNAETQSAEERLKNYHALAGSLQSANSHLSRLMEQMDTLAPRVDQAAHDASKE QVLLWQDELRSLQAAVGDLIEDCENRFVQSKDFETEMKRTLDWLQQVRDDLGYAVIVDVR VEKVQEEIRKQQIMQEEVQSRLRIVAALSTREKQEYISANELVPAHVDTSLEEMAKLQAD VQKALSSKQITLEEALVLCQRYHFRMQSACEWLEDAVSFLQQASLGVDVENYEECLRQQG DILATEQEFLIHLEELQGLLPQLENLVNPTAKEQLRVSVESAKQRGVEVRDQLQCHQDVL HSCVAQWKSYQEARQTVIELMNEAEKKLTEFSTAKAATSQEAEDKLCSHRSLVSLVNGFQ EKLSGLEEQAAQLELVGSDASKATISRSMTTVWQRWTRLRSVARGRERVLEDTAQDWRTF REKMLKVRAVSDELQSRFPDSAVEKASKATLQSLLDQHDLLSQDLERELSALTLLRQYAL SLLHDVEVPSPTNDQDELPSLKEIRAVQDQMESLLTQSRTKRAQAAQELRDREEVEKELS VVKAWIQETRELLLNPTPDIDSLLQELEVVHGDVITYRQNVDKLAEQQQSKYLDLYTILP SEISMQLAEVSLALGAIEDQVLSKEREIQKTREIKEDFSSRIHGISEKLKAISAKFKEKS PDVDHAKEEVKSLAEDLDCCGRTLSELDAAVQEFGRRNPLLAKQLGDAISKLSEMHHHTT RLADCRNNWLKKAVCYLDEYNEMLDFIVRWSEKAKSLVRANIIWNSSVHLQEQIRMYQAV LRESRELHGDLESMAEKVELLSEVLQVESMSQQVCELSRHTEELQQSIKTRLQSLEDANK SMEALEYEVKALHVALEQVQATLTSPELARQSLKEQLAQRQRLLADMESFKQQVQAVQLC QSALQVPEEVMPNLAICRTALRLQQEASQLQHVAIQQCNILQEAVVQYEQYEQEVKDLQG LIEEAHRVIQDRPIPTNNIQELQAQIHHHEELAQKIKGYQEQIASLNSKCKMLAVKAKHA TMLLTVSDVEGLPEGLQEIEEEKSKKSSAQAVMMTAGRCHTLLSPVTEESGEEGTNSEVS SPPVCRSPSPITHTEIGRGTLTRAPIQELYDPTFESVANLDDLQRSWETLKNVISEKQRS LYEALEKQQHYQGSLQSISSKMEALEAKLNEPLEADKSPDSHIKAHEGLIEEIQSVQEEI NRLQTSFTEDLASYAVDSDMAEQLAMQSSLAVLAERMATIHMKASGKQQLLEDRVSDRLE GQRQEEAIQLYHSQVDELDQWLTRMRSAVTFILEPQPLEETDMEDQLAESQNMLLEIEEK VLALSELFMHSENLLLEGRTETREEAEQLARKLHMLKGGLLELQRMLQDKQTNFQGSLQE QEDSESDSSLSHSPSVQDWLAQARTTRSQQHQDSLQRQRELEEQLAEQKKLLQSVASRGE EILIQQASPSSASTTEPFSPAALVERESLAAREQMRQRWESLRLELKTKLQLLQKTLEQD HKQPVYSRASRVATAGSMFKGETQADKSSLKTLYDNFRQTIEEMTSQPGGGEAQVPQMEQ QLYAAVSSTSSWLDGVENNVFSGSVLLAENAETQLQKQETLENDVRHVTEDVKLSQALLA GSSGLKHEDRALLEDNLDCLKERLGALGCALGQRCDHMRTRTHELTAYQTELQLLQTALI ETKCQILQALAGAMDRPASKQLEVIASAEESLKDFEQRITELKTRGAALQADQISTNKLL KLQDSYEELVMTVGSRRSGLNQNMALKDQYERALQDLTDLVDTAEDKMAADQRIIASSVE DVQNHLDKHKEFFQGLESHMILTETYFRKITGLMLPKESQALEETLAEAQSVLKEAHSKG VELECILETWCRLVQDYQSLNRQLEAVEGSIPAVGLVEETEERLMDRISLYQGLKGRLTE HQHKLYQVLDEGKHLLLSVCCPALESQLTLLGEHWLNNTSKVNKELQRLEAILKHWTRYQ RECAELSQWLQSALERLEFWNTQAVLVPQELETVRDHLSAFLEFSKEVEGKSSLKSSVVT EGNQLLRLKKVDTVVLRSDLARIDSQWTELLTRIPVVQEKLHQIQMEKLASRHAISELFN WISLMENVTEEDEENLKSAVGSNVIQDYLQKYKGFRVDLSCKQLTVDFVNQSVLQISGQD VESKRSDKTDFAERLGAMNRRWQILQGRINERIQFLESLLEMWLEYESSVQALKSWMTTQ EERLKRKHRIEDLTSVQNALKDCQEMEELVKEKEKELERVEEQGCALVQNKTDEACAIVM ETLQGVNHTWANLDHLIGQLKISLKSVLDQWSLYKRASEEINGHLMEGRYSVSRFRLLTG SLEAVQLQVHSLQDLQEELEKQESSLRRFGAVTHQLLKECHPSVSDSLNNALKDVNARWT GLLEEIAERLRSSKALLQLWQRYKELYEQSCSSIQLQEEKADQLLKLACSKDIADEEVSD WIQECSEMLRSQAPVQASLQVLQELGNQLKQQVDTSAASAIQSDRLSLTQRLAAVEQALT RQLTTLQTGVQDYEIFNDQLNSLGCWIVEAEEALKVQDPNGSTDLTAIQDRMEELKRLML KFSSMAPELERLNELGYRLPLNDSEIKRMQNLNRSWSTASAQTTERFSKLQSFLLQQQTF LEKCETWMEFLVQTEENLAVEISGNYQSLMEQQKAHELFQAEMFSRQQILHSIISDGQRM LEQGQVDDRDEFNLKLALLSNQWQGVVRRAQQRRGIIDGLIRQWQRYREMVEKLRRWLVE VSHPAEALQAGTTVPLQQARSMLDAVQLKEKVLQRQQGSYILTVEAGRQLLLSADSRAEV GLQAELTEIQERWKHANICLDEQKKELAILLKDWERCERGIGGSLEKLRAFKRQLSQPLP DHQEDLQAEQMRCKDLENTFDGWTGDLAHLTVLRESLSCYISAEDLSVLQERIELLHRQW DEICHQLSLRRQQVSEKLNEWAVFKDKHKELCEWLTNMESKVSQNGDISIEEMIEKLRKD YQEELTVAEENKLQLHQLGERLARASHKSKAAEIEQKLNKVSDRWQHLLDLIGARVKKLR ETLVAVQQLDKNMSSLRSWLAHIEAELSKPIAYDNCDFQEIQRKLDLQQELQRDIEKHST GVASVLNLCEVLLHDCDACATDTECDSIQQATRSLDRRWRSICALSMERRLRIEETWRLW QKFLDDFSRFEEWLATSEKTAALPNSSGVLYTVAKEELKKFEAFQRQVHESLTQLELINK QYRRLARENRTDSSCRLREMAHDANQRWDNLQKRVASILRRLKHFISQREEFETARDGIL VWLTEMDLQLTNIEHFSECDIQAKIKQLRSFQQEISLTTAKIEHIFHQGEALIEKSEPLD AAVIEEELEELQRYCQEVFGRVERYYKKLIRLPLADDDTEVSFSDRELELDEPGDLSSLP WNERLGDGLLSPLPSSGRSASLAAQLRTERSGRDTPASVDSIPLEWDHDYDLSRGLESAS RALREQQSEEGDFLQRPASALSDVVIPESPEAYVKLTEQTLRSSTGDVASTDSHSHPLDA SRYHLQQMDSSRSRTPTSTELDASYMGYMRLLGECRGSIDTVKRMGFELKEEEDTVSGLA DPSSSESQTSGVIERWELLQAQDLSKEMRTKQNQQQWQQLISDLNNIWMWLGETEEELEQ QRRLDLSTDIQTIEQRIKKLKELQKAYDKRKAIVLSINLCSAEFVQSDTEESRELQAKLK DMNNHWDKLGGSLEEWRSSLQEALMQCQDFHEMSHGLLLWLENIDRRRNEVVPIDPIQDS DTLHEHHKTLTQIRQELLDSQLKVASLQDMSLQLLVNSQGSECLEAKEKVHVIGNRLKLL LKEVTRDLRELAKILDITSSQQDLSSWSSADDLDTSGSLSPVSGRSTPSRRRSQRGKCSL SQPGPSVSSPHHRSHSDVGSASFPSDSEASPGNGSSFLWRVLWVALPLQFFLLLLVVFAF LLPITEEDYCSQSNNFAHSFYPMLSYTNGPPPV NT seq 26382 nt NT seq  +upstreamnt  +downstreamnt atggcctctccaaggcagttcggtcgatcgtctgtggacatcgctaatgtgatgcaaaaa ctgcaggatgagcaagaggcggtgcagaagagaaccttcacaaaatggataaattctcat ctagcaaagtataaaccaccactagaggttaacgacctttttgaggacatcaaagatggg gtgaaactcttggctttgttggaggtgctttctggccaaagattaccccgtgagcaaggc cgccagctgaagaggatccactgggtttccaacattggcactgcactaaaattcctcgaa ggcaggaagtctgtgtatcgaggatctccgatcaaacttgttaacattcatgccactgac atcgcagatggacgaccatcaattgtccttgggttgatatggaccattatcctctacttc cagattgaggagttaaccagcaacctgccagccctccaagccctgtccaacagcaattct tctgtggagagtatagctagctctgaaacaggaagccctcccatgaagcggaaggtggtt aacaaatttcagggcaatgccaagaaggccctgctcagatgggtgcagtgcacagcagcc aagtatcatggaatagaagtgaaggactttggtcccagttggcgcgatggtgttgctttc cagtcggtggtgcacgccatcaggccagacctggttgacatggaggtggtgcagaggcga agcaacagggagaatctggaggatgcctttgcacttgcagaaaatgagctgggcattccc cgtctgctggatccagaagatgtggacgtagacaagccagatgagaaatccatcatgaca tacgtggctcagttcctcaagcactacccaaaccctcactccgagactgatgggcaacag gatgagtttggtccccaagatatagaacaaatgcttgagagagaagagcggaagatgctg agagagctgaaggtgtttttggatcagctggagagagatgtgctgcgggcccagggagca gaaggaaacctcactgacaaatatcaggcatttaagagcttccgtgtacagtatgaaatg aagaaaaagcagacagatccacttctgcagccagtccacagagacggcaagctgtccgtg gaccaagcactagtcaaacaggcatgggaccgtgtgtctgccaggctgctggactggcac atccatctggacaagtccttgcctggccctctgggagtgattggagcctggcttcacagg gcagagatggctctgagagaggacattcccatccaacacgctcatgaagagacagccaat gttcttcacagaaaactagagcagcataaggaggtgttaaaaaacttagaatcgcacagg cagaccttccagcagatccacagggacagatcagtgaatggggttcctgtcccaccggag cagctccaagatatggctgagcggttcaactttgtgtctacatcatcatatgctcacttg ataaaactggaattctgggaaattaagtatcgactgatggcatttctggtgttggctgag tcaaagctcaagtcctggatcattaaatatggcagacgggactctgttgaactcctgttg caaacctaccttacttttgtggaaggccacaggttctttgagcagtatgaaataatctac acaaacctcaagcaagctgcagaagtttatgtaaagtcagacagttcaaggtctaagacc tgtaacaaagttgatgaagcagaaggggttagtaaattcctcagtgatgccacagctcag tggaagaacctggcattggaggtgcggagtgttcgcagcatgttggaggaggtgatctct aactgggagaagtacagtagcacagtggcagctctgcaggcctggctagaggatgctgag caaatgctcaatcactcagagaatgccaaacgtgatttcttcagaaacctctctcactgg atgcagcagcacacggacatgaacgatgctgggaacttccttattgagacatgtgatgac acagtctcacgagatctgaaacagcagcttctcctcctgaatgggagatggagggagctg tttgtcaaagtcaaacattatgcaagagcagacgaggttgataagctgaggcaagactac caagatgggattaatacgttgaaaatgttcatggatgcaaccaatgagaaaatgactgct cctgtccaagtatctttcctgaacgtcagagcatttgctcaagatgttgaggatatcaag cacaaagtgccagccatggaagccgcctgtaaggcagcgtgccgtacagctcagctgttg accaaagacacgccacaggaggaagtttcacagatgatggctgtgatggcctcgatcaaa gaacagctgagcaaggtaagggagagatgtttgcctctgctgagggagtcccagtctcta ttacctccgctggaagaaatggagaaaaacatcacaggtttctaccaggctctggagaag gccagtcatatcaccagcaccactgactctgagggaccagtagactttaaacagaaatgc caggagctggcgaccttcacacatagttgtaagaagtgtttgacatcaatagagagaaac caccagaccatccagaaaataatgagcagcagtaaaaccctcgagcacatggacatgagc cttttgcagaaaagagtaggagacctgcagtcctcctcacaggccatgattaaggaatct acagagtggcggaagcatgtggaggcaaacagcagcctcatgaagaggtttgatgagtca cgggtagagctggagaaggttctgaaaatggcacagaactgtttgacagaaagaggcaac ccagaggagctgctcaagaaacacacagagttctttggtcagctggaccagcgcgtcttg aacacattcctcaaggcctgtgatgagctgacagacattttgccagagcaggagcagcag tcgctacaggaaacagtcaggaagctgcacaaacactggaaggatattcagactgatgcc ccctttcacctcctgcatcttaaagtggaggtggaaaggagcaagctgatggcgttgctg caggagtgccaggcagaggtgaccagggagaaccgccacctggctagcatcgggagcgag aggctcatcaaggagcacagggccttctttagggaaaagggccctcagtccatttgtgag aaaaggttgcagctgatggaggaactttgtcaaaagctccctgagggtgaccctgtccac cagatcctggaaacagcgaaaaaggacttctctgaggtgcgggaggaaatcgagagcacg catcagaaactaatgcagcacccagataaatggaaggagtacaatgcaaggtacgctgaa ctctcctgctggcttatatctaaagaaagtcaactaaggctgctgagaaacagagccaat gaccccagaaaatatggccaggtgaagtcttccatcatggagctgaggaatgatgcagag ctacaggaggggaatcttggctggttgaaagctcgtgtggctgtgcttattgagatttgt gctgacagcgatggccagaggcaaggaagtgcactcagcaagctctctactgattttaag ggtcttcttgcttctctctcagaggctgaaaagatggtgctggctgtgggggactgtgta cagttcagagaggaggtacaagctactttgggtgatcttatacaggggcagaaagatgct cagactgaggtcaccaaaatattggacagtccaactgttagagaagcccagcaactgcat ctcgttcaccagcaactattaaaacgcctaaagctgaagagaaaggatgtccagcagctg atcaccagaggtcagcagctccaggctgaggagggtttgggagagactctgcagcaggac ctgcagagtttagagaacacgctcagcaaaatggagcagaatatggactcacaggagcaa agccttgaggtcacattagcagcctggcaggagtttgacagccagcaggaggccgtatgt gagtttgttaataaggcacgctcaacaatggacagagacctgaacttcagcagtccagag agcctggctgttgaacttgaccaggccagagtgttgctgaaacagtgtgaagcagaagcc tcacacatgaacattttgctgaagagagcaacagaaatccagcttggtccaaagaacaag actctgcttttacaacaaggtcgttcactcagtgagcaagtggacaaagtagaagctgga ctcaaaaaagacgtcaagactctggaagaaatgaaaagtcagtgggatcagtttggaggc gggtttgaaaccttttccttgtggatatctgacaaggaaaagcagctggatgtactaaag tcttctaccttacctcttgagcaacagatcaacacagtcaaggctatttgtgcagagctt caggagcgagctgaggttccttctcagttggaggcagaatcccaggcgttagcccagttt gtatcttcaggggaggcggctcgcatcaaggcccgtctgacccaaatcggcagatactgg 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gctgagaactttgtcactcagctggagctccaagatctgcaagagcgctataaaactatc aaagacaatgccatgagagcagttggcaaagcagaggagctggtgaaagcccatcaggag tatcagcgcgggctccatgcatttgaggactggctggaacaagaacaagagaagctcagc tgctacacccaactggagggtgatgttgatatgctggaggagactttgcaaaagctgcag gagctgcagctgcactgcacagagggccaggctttgctaaacaccctgctggtcagtcgg gaactggtcattccctggggcctgcctcagatcgaagaccgagcactggagaccttgcag caggagtggaggttgtaccagggccggctggccgacacccgagctcagctcaacagtgct ctggccaaactcaggcagatggagcaaaagtttcagcgtctagacagctggctaaaggcc atggagaccaaagcacaactccgtggccaccggcggtccgatcgcaccaccaaagatgct caactccagctactaaagagctggcaggaagaagtgctggtttatcaagaggagatggag ggcctcagtctcttggcgcagcaagttctggatgagacccatattagcagccagatcagt agcagagccaccaagattacagcccgctaccacgtcctgcttctgcatttactggagacg atcaaacagctccaggaggaagtgtcttgcattgaagaggcacagtgtgtctttggcacc ttctcagactggctcagcacagctcagaataacttcagctctgtggctatcagtgttgat gcagtggatcgttttgctatggagagaaagatgaaaaaactagaggctcttcaggcagac atggagcagggtcacacttacttgaagacaatgagggagaagacagagcgatccatggca 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gtggataaattagcagagcagcagcaaagcaagtacctggacctctacactatactgccc tctgaaatctccatgcagctggcagaggtctcacttgcattgggtgccattgaggatcag gttctatcgaaagagagagaaattcagaaaaccagagaaataaaagaggacttcagctct agaatccacggcatctctgagaaactcaaagcaatttctgctaaattcaaggaaaaatct cctgatgttgatcatgccaaagaagaggtcaagagcctggcagaggacttggattgttgt ggtcgcaccctttcagaactggatgctgctgtacaagagtttggccgcaggaacccccta ctggccaaacagcttggtgatgccatcagcaaactatcagagatgcatcaccacacaaca cggctggcagactgtaggaacaactggctcaaaaaggctgtctgctatttagatgagtat aatgagatgctggacttcattgtgaggtggtcggagaaagcaaaaagcttggtgagagca aacatcatctggaactcctctgttcatctgcaggagcagattcgaatgtaccaggctgtc cttcgtgagtctcgggagctccatggagacctggaatccatggcagagaaagtggagctt ctgtctgaggtgctgcaggtcgagtctatgagccagcaggtttgtgaactcagtcgacac actgaggagcttcaacaaagcatcaagacacggctgcagagcttggaggatgcaaataag agcatggaagccctggagtatgaagttaaggccctacatgttgctctggagcaggtccaa gccacactgacctcaccagagttggcacgccagagcctcaaagaacagctggctcagaga cagcgtctgttggcagatatggagagcttcaagcagcaggtgcaggcagtgcagctgtgt cagagtgctctgcaggtcccagaggaggtgatgccgaacctcgccatctgtcgtacagcg ctgcgtctgcagcaagaagccagccagttgcagcacgtggccattcagcaatgcaacatc ctacaggaggcagtggtgcagtatgaacaatatgaacaggaagtaaaagacctacaaggg ctgatagaggaggcacaccgtgtcattcaggaccgaccaatccccacaaacaacatccag gagctgcaagcccagatccatcaccatgaagaactggcccagaagattaaaggttaccaa gagcaaatcgcctctctgaactcaaaatgcaagatgctggcagtgaaggcaaagcatgcc accatgttgctgacagtgagtgatgtggagggactgcctgaggggctgcaggagatcgaa gaggagaaatccaagaaatcttcagcacaagctgtcatgatgacggctggccgctgtcac accctcctgtctcctgtaactgaggagtctggggaggagggcactaacagtgaggtctct tctcctcctgtctgtcgctctccttctcccatcactcacactgaaattggaagaggaaca ctcacaagagctccgatccaagaattatacgacccgacttttgagtctgtggccaacttg gatgacttgcagcgctcatgggagacgttaaagaatgtgatcagtgagaagcaaaggtct ctgtatgaagctctggaaaagcaacagcattaccagggctcactccagtcaatctcttct aagatggaggctctggaggccaaactgaatgagcctctggaggcagataaaagcccagat agccacattaaggcacatgagggtctgatagaagagattcagagtgtgcaggaggaaatt aacaggctgcagacgagcttcacagaggatctggcctcctatgctgtagattcagacatg gctgagcagctggccatgcagtcctccctggctgtgttggctgagaggatggccaccatc cacatgaaggcctcagggaaacagcagctattagaggaccgtgtcagtgaccgtctggag ggtcagcgtcaggaagaggccatacagctctatcattcgcaggtagatgaactggaccag tggttgaccagaatgcgcagtgctgtaaccttcatccttgaacctcaacctctagaggag acagatatggaggatcagcttgctgaatctcagaacatgctgctggagattgaagagaag gtactggccctgtcagagctgttcatgcacagtgagaacctgctgctggagggtcggaca gagaccagggaggaggctgaacagctggccagaaagttacacatgttgaagggtggcctg ttggagctgcagaggatgctacaagataagcagactaactttcagggctctctgcaggag caggaggacagtgaatcagactcgagcctctctcacagtcccagtgtacaggactggctg gcccaggcccggaccacacgctcacaacaacaccaggacagtctgcagagacaaagggaa ctggaggagcagcttgcagaacagaaaaagttgctccagtcagttgctagcagaggagag gagattctcattcagcaggcgtcacccagcagtgccagcacaacagagccattttcgcca gcagctttggttgagagggaatctctggctgctcgagagcagatgaggcaaagatgggaa agcctaagattagagctcaaaaccaaactgcagctcctgcagaaaaccctggagcaggac cacaaacagccggtatattccagagcgtctcgtgtggccacagctggatcaatgttcaaa ggagaaacacaggctgacaaatcctccctgaagactctgtatgataacttcagacaaaca attgaagaaatgacatctcagcccggtggtggtgaggcacaggtgccgcagatggaacag cagctctacgcagctgtgtcatccacctcctcctggctggatggtgtggagaacaacgtc ttctctggctcagtgctgctggctgaaaatgcagagacccaactacaaaagcaggagacc ttagaaaacgatgtgaggcatgtcacagaggatgtaaagctcagccaggctctgctagct ggatcgtcaggattgaaacatgaggaccgagccctgctcgaggacaaccttgactgcctt aaagagagattaggagctctgggttgtgctctggggcaacgctgtgaccacatgaggacc agaacacatgagcttacagcttaccagactgagttgcaacttctccaaactgctttaatt gagaccaagtgccagatcctacaggccttagctggagccatggatagaccagcctcaaaa caattggaggttattgccagtgcagaggaaagcctgaaagactttgaacagaggattaca gagctcaaaaccaggggggcagcgctacaggcggaccagatatcaacaaacaaactacta aaactccaggattcctatgaggagctggtaatgacggtgggttcccggcgcagtgggctg aaccagaacatggctctgaaggatcagtacgagcgtgctctgcaggacctgactgacctg gtggacacggctgaagacaagatggctgccgatcagaggatcattgccagctctgtggag gacgtccagaatcacttggacaaacataaggagttcttccagggtctggagtcacatatg attctaacagaaacgtacttcagaaaaatcactggcttgatgctgccgaaagagagtcag gctctggaggagactttggctgaggctcagagtgtcctcaaagaagcacacagtaaagga gttgagctggagtgtatcctggagacttggtgtcgcttggtgcaggattaccagagcctg aaccgccaattggaggcagttgaaggaagtatccctgccgttggcctggtggaggagact gaagaaaggctcatggaccgaatctcattgtatcagggtctgaaggggagactgacagag caccagcacaagctataccaggtactggatgagggcaaacatctcttgttgtcagtgtgc tgtcctgcactggagagtcaactcacgctgctgggggagcactggctcaacaacaccagt aaggtcaacaaggaactacaacgcctggaggccattctaaaacactggaccaggtatcag agggagtgtgcagagcttagccagtggctgcagtctgctctggagcgtctggagttttgg aatacacaggcggtgttagtcccacaggagctggaaactgtcagagaccatctctctgcc ttccttgagttttcaaaggaagttgaaggcaagtccagcctaaagagctcagtggtaacc gaaggcaaccagctgctgcgtctgaagaaagtggacacagtggtgctgcggtctgaccta gcacgcattgactctcagtggactgagctgctcacacgcatcccagttgtccaggagaag ctgcatcagatccaaatggagaagttggcctcccgtcatgccatttctgagctgtttaac tggatctcactgatggagaatgtcactgaggaggatgaagaaaacctcaagagtgcagtg gggtcaaatgtcattcaggattacttgcaaaaatacaagggcttcagagtagatttaagc tgtaagcagctgactgtggactttgtcaaccagtcagtgttgcagatcagtggtcaggat gtggagagcaagcgcagtgataagacagactttgctgagcgactgggagccatgaaccgt cgctggcagatcctacaaggccgcatcaatgagaggatccagttcctggagagccttttg gagatgtggttggagtatgagagcagcgtgcaggccttgaagtcctggatgacaactcaa gaagaaagattaaagaggaaacaccggatagaggatttaacatcggtgcagaatgctctc aaagactgccaggaaatggaggagttggtgaaggaaaaagagaaggagttagagagggtg gaggagcagggctgtgcgcttgtccagaacaagaccgatgaggcatgtgctattgtcatg gagacgcttcagggtgtcaatcacacctgggctaacctggaccatttgatagggcaacta aaaatcagcctgaaatcagtgctggatcagtggagtctgtacaagcgggcttcagaagag atcaatgggcacctgatggagggaaggtactctgtatctcgtttccgcctcctcacaggc tccctggaggctgttcagctgcaagtgcatagtctgcaggatttgcaagaggaactggag aaacaggagagcagtctgaggaggtttggtgctgtgacccaccaactgctgaaggagtgt cacccgtcagtgtcagattctctcaacaatgcccttaaggacgtcaatgcaagatggact ggcttactggaggagattgcggagcgcctgagaagcagcaaagccctccttcagctatgg cagcgctacaaggagctttatgaacagagctgcagcagcatccagctgcaggaggaaaag gcagaccaactccttaagctcgcctgcagcaaggacatcgctgacgaggaagtgtctgac tggatccaagaatgcagtgagatgctccgttcccaagctccagtgcaggcctccctgcag gttctccaagaattgggaaatcagctgaaacagcaggtcgacacatcagcagcatcagcc atccagtcagatcgcctctcactcacccagcggctggctgctgtggaacaggcccttacc agacagctcaccacactgcagactggagttcaagactatgaaatctttaatgatcagctg aattcactggggtgctggatagttgaagctgaggaggctctgaaggtgcaagatcccaac ggctccactgatctgacagccatccaagaccgcatggaggagctcaagcgactcatgctg aaattcagcagtatggctcctgaactggaacgtcttaatgaacttggttatcggctccct ctcaacgattcggagatcaagcgcatgcagaacctcaacaggagttggtcaaccgcctca gcacagaccacagagagattcagcaaactccagtccttcctgctacagcagcagaccttc ctggagaagtgtgaaacatggatggagttcttggtgcaaacagaagagaatcttgctgtg gaaatttctgggaactaccagagtttgatggagcagcaaaaagctcatgagttattccaa gccgagatgttcagtcggcagcagatcctgcactccatcatcagtgacggacagaggatg ttagagcagggtcaggtagatgacagagacgagttcaacctgaagttggctctcctgagt aaccagtggcagggcgtagtgcggcgtgctcaacagaggcggggaatcatcgatggtctt atccgccagtggcagcgctacagagaaatggtggagaagctacgcagatggctggtggag gtctcccaccctgcagaagcccttcaggcagggaccacagtacctctgcagcaagcccgc tccatgctggatgctgtccagctgaaggaaaaggtgctgcagcgtcagcagggcagctac atcctgacagtggaggctggcagacaactgctcctgtcggctgatagccgggcagaggtg ggcctgcaggcagagcttactgaaatccaggagcgatggaaacatgccaacatctgcctt gacgagcagaagaaagagcttgccatcttgttaaaggactgggagaggtgtgagagaggt attggtggatcactggaaaaacttcgagccttcaaacgccagctctctcaacctcttcct gatcaccaagaggatctgcaagctgagcagatgcgctgcaaggacctggagaatacattt gatggctggactggggatctggctcatctgactgtgctgcgagagtccctgtcttgctac atcagtgctgaggacctgtctgtcctgcaggaacgaattgagctgctgcatcgacaatgg gacgaaatctgccaccagctgtcactgcgcaggcagcaagtgagtgagaagctgaatgag tgggctgtattcaaagacaagcacaaggagctctgcgagtggctcaccaacatggagagt aaggtctcccaaaatggagacatcagcattgaggagatgatcgagaagctccgcaaggac taccaggaggagcttactgtggctgaggagaataagctacagctgcaccagctgggagag cgtttggccagagccagtcacaagagcaaagcagctgaaattgaacagaaactcaacaaa gtcagcgaccgctggcagcacctcctggatctcatcggagccagagtgaagaagttgaga gaaactctggtggcagtgcagcagctggataagaatatgagcagccttcgctcctggctg gcccacatcgaggctgagctatctaaacccatcgcctacgacaactgtgacttccaggag attcagagaaagcttgatctgcagcaggagcttcagcgtgacatagagaagcacagcact ggagtggcttctgttctcaatctgtgtgaggtgctcctgcacgactgtgacgcctgtgcc acagatacagagtgtgactctatccagcaggcaactcgtagccttgatcgccgctggagg agcatctgtgccttgtctatggagaggagactcaggattgaggagacgtggcgtttatgg cagaaattcctagatgacttttcacgatttgaggagtggctggccacttcagaaaagact gctgctctgcccaactcctctggtgtactttacactgtagccaaggaagaacttaagaaa tttgaggccttccagaggcaagtccatgaaagcctaacccagctagagttaatcaacaag caataccgccgcctggccagagaaaaccgcactgactcttcctgccgtctgagggagatg gctcacgatgccaatcagcgatgggacaacctgcagaagagggtggcatcaatcctccgc aggcttaagcactttattagtcagagagaggagtttgaaacagccagagatggtatcttg gtgtggctgacagagatggacctgcagctgaccaacatcgaacacttctctgagtgcgac attcaggccaagatcaaacaactcaggtcgtttcaacaggagatttccctcactacagcc aagatcgagcacatctttcaccagggagaggcgctgatagagaagagcgagcctctggat gctgctgtcatcgaggaggagctggaagagctgcagcgctactgtcaggaagttttcggt cgagtggagcgctactacaaaaagctcatacggcttcctcttgcagacgatgacactgag gtgtcattctcggaccgtgagctggagctggacgagcctggtgatttgtccagcctgcca tggaatgagcgtttgggggatggcttactgtcacctctgccctcctccggccgctcagcc tccctggcagcccagctgaggactgagcgctcgggcagggacaccccagccagcgtggac tccattccccttgagtgggaccatgactatgacctgagccgcgggctggagagtgcaagc agggccctgagagagcagcagagtgaggagggagacttcctccagcggcctgcctcagcc ttgtcagatgtagtgatcccagagagccctgaggcctatgttaaacttacagaacaaact ctgaggtcctccactggggacgtcgcctctacggactcacatagtcacccgctggacgcc agccgttaccacctgcaacaaatggatagcagccgcagtcgcacacccacaagcacagaa ctggatgcctcgtacatgggatatatgcggctgctgggtgagtgccgtggcagtattgac acagtgaagaggatgggctttgagctgaaagaggaggaagacacagtgtctggactggca gatcccagcagctcagagtcccagacatcaggagtgattgagcgctgggagctcctgcag gctcaggacctcagcaaagagatgcgcacaaagcagaaccagcagcagtggcaacagctg atctctgacctgaacaatatttggatgtggctgggagagacggaggaagagctggagcag cagcggaggctggacctcagcaccgacatccagacaattgagcagcgcatcaaaaagctc aaggagctgcagaaggcttatgacaagcgcaaggctattgtgctgtccatcaacctgtgc agtgctgagtttgtgcagtcagacacagaggagtcccgagagctacaggccaaactgaaa gacatgaacaaccactgggacaaactgggcggctcactggaggagtggaggtcttcatta caggaagctcttatgcaatgtcaagacttccatgagatgagtcatggtctgctcctttgg ttggagaacatcgaccgcagaaggaatgaggtggttcccattgaccccatccaggacagt gacactctccatgagcatcataaaacacttacgcaaatccgccaggagctgctggactcc cagctcaaagtcgcctcgctacaagacatgtccctccagttgctggtcaactctcagggc agcgaatgcctggaggccaaggagaaggtccatgttattgggaaccgtctcaaactgctg ctaaaggaagtgacccgagacctcagagaactggccaagattctggacatcacaagcagt caacaggatctgtcatcttggtcatctgcagatgacctggatacatctggttccctcagt cctgtatcaggaaggagtacaccaagtcggcggcgatcgcaacggggcaaatgtagtctg tcacagcctggaccctctgtgagcagtccacaccacaggtctcacagcgacgttggatcc gcttccttcccttctgattcagaggcatcgccgggtaatgggtcctcctttctgtggcgc gtcctctgggtggcgctgcctctccagttcttcctgctcctgttagtggtctttgccttc ctgctgccaataactgaggaggactactgttctcagtccaacaactttgctcattccttc tacccgatgctcagctacactaacggaccacctccagtgtag

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