KEGG   Paraburkholderia largidicola: PPGU16_03370
Entry
PPGU16_03370      CDS       T10364                                 
Symbol
leuA_1
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
plad  Paraburkholderia largidicola
Pathway
plad00290  Valine, leucine and isoleucine biosynthesis
plad00620  Pyruvate metabolism
plad01100  Metabolic pathways
plad01110  Biosynthesis of secondary metabolites
plad01210  2-Oxocarboxylic acid metabolism
plad01230  Biosynthesis of amino acids
Module
plad_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:plad00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    PPGU16_03370 (leuA_1)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    PPGU16_03370 (leuA_1)
Enzymes [BR:plad01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     PPGU16_03370 (leuA_1)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer BP74_N
Other DBs
NCBI-ProteinID: BCF87270
UniProt: A0A7I8BFZ5
LinkDB
Position
1:complement(382040..383698)
AA seq 552 aa
MLRNPAEKYRPFPTVRLTGRKWPTRTIERAPIWMSTDLRDGNQSLIEPMSIAQKTEFFEM
LVAIGFKEIEVGFPSASQTDFDFVRKLIDEKRIPDDVTIEVLVQSRADLIARTFEALEGV
PRAIVHLYNAIAPSFRKIVFGLSQEQVKALAVEGTRIIREHADARPQTHWTYQYSPETFS
MTELPFAREVCDAVAQTWRPTRDHKMIVNLPATVEAATPNVYADQIEWMDRNLGYRDSIV
LSVHPHNDRGTAVAAAELALMAGADRIEGCLFGNGERTGNVDIVTLAMNLYTQGIDPGLD
FSDIDAVRRVVERCNQIPVHPRHPYAGDLVYTAFSGSHQDAIRKGFAQQKPDAVWEVPYL
PIDPADVGRSYDAVIRVNSQSGKGGATYLVERGMGFALPRRVQIEFSHAVQSVADQSGEE
VTGDAICALFAREYFEADGPAQRVNGSTVRWNKREIAVPATAAASVDGHEAYAKAVAQEM
AGASKQTIEITSFETARTTDGRTVVFVASRVGEQPMRHGIGVAEDEMTAVVDAVVSGVNR
AGWAAVDRRVAA
NT seq 1659 nt   +upstreamnt  +downstreamnt
atgttgcgcaaccctgccgagaagtaccgccctttccccaccgtccgtttgaccggccgc
aagtggcccacccgcacgatcgagcgcgcgccgatctggatgagcactgatttgcgcgac
ggcaaccagtcgctgatcgagccgatgagcatcgctcagaagaccgagttcttcgagatg
cttgtggcgatcggtttcaaggagatcgaagtcggttttccgtcggcgtcgcaaaccgac
ttcgatttcgtccgcaagctgatcgacgaaaaacgcattcccgacgacgtgaccatcgaa
gtgctcgtgcagtcgcgcgccgacctgattgcgcgcacgttcgaggcgctcgaaggtgtg
ccgcgcgcgatcgtccatctctacaacgcgatcgcgccgtcgttccgcaagatcgtgttc
gggctgtcgcaggaacaggtgaaggcgctcgcagtggaaggcacccgcatcattcgcgag
catgccgacgcccgtccgcagacgcactggacttaccagtattcgcccgaaaccttcagc
atgaccgagttgccgttcgcgcgcgaagtctgcgacgccgtcgcgcagacgtggcgtccg
acgcgcgatcacaagatgatcgtgaacctgcccgctacggtcgaagccgcgacgccgaac
gtgtacgccgaccagatcgagtggatggaccgcaatctcggctatcgcgacagcatcgtg
ttgtccgtgcatccgcataacgatcgcggcacggccgtcgccgccgcggaactcgcgctg
atggcgggcgcggaccgtatcgaaggatgtttgttcggcaatggcgagcgcacgggcaac
gtcgatatcgtgaccctcgcgatgaacctctacacgcagggtatcgaccccggcctcgat
ttctcggacatcgacgccgtgcgtcgcgtggtcgagcgctgcaaccagattcctgtgcac
ccgcgtcatccgtatgcaggcgatctcgtctacacggcgttctccggctcgcatcaggac
gcgatccgcaagggcttcgcgcagcaaaagccggacgccgtctgggaagtgccgtatctg
cccatcgatcccgccgacgtcggccgcagctacgacgccgtgattcgcgtgaacagccag
tccggcaagggcggcgcgacgtatctggtcgagcgcggcatgggcttcgcgctgccacgg
cgggtgcagatcgaattcagccacgcagtgcaatcggtggcggatcagtcgggcgaggaa
gtgacgggcgacgcaatctgcgcgctctttgcccgcgaatacttcgaggcggacggcccg
gcgcagcgcgtgaacggatcgacggtgcgctggaacaagcgcgagatcgccgttcccgcg
acggcggcagcgagcgtcgatggccacgaagcgtatgcgaaggcggttgcgcaggaaatg
gccggggcttcgaagcaaaccatcgaaatcacgtcgttcgagaccgcgcgcaccaccgac
ggccgcacagtggtattcgtcgccagccgcgtcggcgagcagccgatgcgtcacggcata
ggcgtagcggaagacgagatgacggccgtcgtcgatgccgtcgtcagcggcgtcaatcgc
gccggttgggcggctgtcgaccgccgcgtcgcggcgtaa

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