Poecilia latipinna (sailfin molly): 106960677 Help Entry 106960677         CDS       T08005                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism plai  Poecilia latipinna (sailfin molly) Pathway plai04020   Calcium signaling pathway plai04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:plai00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     106960677 (ryr3)    04020 Calcium signaling pathway     106960677 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:plai04040]     106960677 (ryr3) Ion channels [BR:plai04040]  Voltage-gated cation channels   Ryanodine receptor    106960677 (ryr3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 Med16_bridge Motif Other DBs NCBI-GeneID:  106960677 NCBI-ProteinID:  XP_014909377 LinkDB All DBs Position Unknown AA seq 4857 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQSVATIQKEHRKFCLAAEGLGNRLCYLEPTSEAKYVPP DMCICNFVLEQSLSVRALQEMLANTGTSSEGKADHEKWRLIKKAGQGGGHRTLLYGHAIL LRHSFSDMYLTCLKTSRSLTDKLSFDVGLQEDSVGEACWWTIHPASKQRSEGEKVRIGDD LILVSVSTERYLHLSNCNGNIQVDASFMQTLWNVQPTCSSGSMAVGYLIGGHVMRLCHGH DESLTIPGADKSEEEQRIVNYEAGKGASRARSLWRLEPLRISWSGSHIRWGQSFRLRHLS TGRYLALTEDRGLVLEDREKCHTKATAFCFKPSKEKGDSGMKRDIDGMGVPEIKYGDSVC FVMHVATGLWLSYLAPDAKSSRLGPLKRRACLHSEGHMDDGLILQRCQHEESRAARIIRN TTFLFKNFIKALDSAAAGETNAVAAYVEEVLQTLNDLIEYFKQPDVDLEHEEKQARLRSL IKQQDLFKEEGMLALLSKCIDRMNLYDSAAHFGEMAGEEAGAAWKDILNLLYELLAALIR GNRTNCTQFSRNLDWLVSKLERMESSSGILEVLHCILVESPEALNIIQKGHIKSIISLLY KHGRNHKILDVLCSLCVCNGVAVRTNQNLICDNLLPKRDLLLQTRLVNDVQSMRPNIFLG IAEGSAQYKKWYYELVIDQVDHFVTGEPTHLRVGWANTKGYAPYPGGGEGWGGNGVGDDL YSYSFDGLHLWSGRIPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDF NTDGFFFPVVSFSAGVKARFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMHVEPVKEYKR DHDGVRDLLGTTQFLSQASFIPTPVDTSQIVLPPHLENIRDKLAENIHELWGMNKIELGW TYGKVRDDNKRQHPCLVDFSKLPETEKNYNVQMSSETLKTLLALGCHVAQVNVHAEEDLK KIKLPKDYMMSNGYKPAPLELSDMKLTPGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQ DVKSRRNPRLVPYALLDERTKKSNRDSLREAIRTMVGYGYDIDPPDQEVVHAIDNQSIET IRFFRVEQTYAVKTGKWYFEFEVLSGGDMRVGWARPGCRPDVELGTDDQAYVFDGYRGRR MHAGSRYFGHPWKKGDVVGCMINMEDKSMIFTLNGELLITSKGSELGFADFETEDGFIPV CSLGMSQIGHMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREITMWFSKRLPTFFNVPQD HMHIEVTRIDGTVDSPPCLKVTHKTFGTQNSNSDMVYCRLSMPVEFYSADRLLDESLKLS QPPKEDGSIDYGSITTYYHSVRVFAGQDPASVWVGWVTPDYHYYSKNFSLSKTQTVTVTL GDERGRVHESIQRSNCYMVCAADALGPSSSSRSNTDLEIGCLVDLATGLVSFTANGKELP TAYQVEPNTKLFPAVFCCPTSSNLFQFEFVKIKDAMPLSSAMFRSEQRNPVPQCPPRLDV QTIVAVLWSRMPNTFLNVETARVSERHGWVVQCLEPLQMMAVHIPEENRCLDIMELSEHE DLRKFHSHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYDVLIS IHLETAKEARLMMNNEFIIPVTDETRSIKLFPDESKRHSLPGVGLSTSLKPRVNFSPVGI ISTKRHQLLYSPQIPLGILKEKAISMLTEAVQGGGSHIRDPVGGSLEYQFVPILKLIGTL LIMGVLTSDEVRLILLLIEPNVFGEAKEGEEGSEVVVAGEKEEVSKNEEKAVEAGEEETK ESKPAAKGLLEKSLPESVKHQMCELLHYFCDCELQHRIEAIVSFSDRFVSKLQYNQKFRY NELMQAFNMSAAVTAKKTKEFRSPPHEQINILLNFSAGEDCPCPEEIQDELTSFHEELRL HCGIPVEEQEEEQDTSIKGRLLALLYKIKGPPQKTEEQPAETEQAAPTNLKELISQTITS WAQESHIQNPELVRVMFSLLRRQYDGIGELLRAMKKSYTISAASVQDGINLLVSLGQIRS LLSVRMGKEEEKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQEIA FPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASEAMRGSTPLDVAASSVM DNNGLALALEEPDLEKVVMYLAGCGLQSCAILVAKGYPDLGWNPIEGERYLSFLRFVVFC NGESVEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMKEAIKISEDPALDLPKSPAGA TAGSGEEEGEVIHMGNAIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAILRSLVPTS DLVGIISIPLKMPVINKDGSVTEPDMSACFCPDHKAPMVLFLDRVYGIEDQSFLLQMLEV GFLPDLKASASLDTEVLSTTETALAMNRYIGSALLPLLTRCAALFGNTEHYAHLVDSTLE TIYRLSKGRSLTKAQRDAIEECLLAICKHLRPSMMQQLLRRLVFDVPLLTEYCKMPLRLL TNHYEQNWKYYCLPSGMGGFGMASEEELLLTKKLFWGIFDSLSQKKYDSELFKMAKSCLC AIAGALPPDFVDTSLGATVEKQESVDAQGNFEPKPINTANISLPEKLDYIANKYAEHSHD KWASEKMSAGWKHGDSLDEQAKAHPLLKPYKSLSEKERETYRWPVKESLKSMLAMNWNIE RTKEGEAMFQQRESEKQRKLSETQSNGFSPAPMDLHNVTLSRELQSMVEVVAENYHNIWA KKKKSELLSKGGGLAHPLLVPYDTLTAKEKYRDKEKAQELFKFLQISGYAITRGLKDMEQ DSSSMEKRFAYKFLKRLLKNIDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLI DQTFKNHCLYFLSTPNKNLSSCGCASNKEKEMVTSLFCKMAALVRHRISLFGSDSAIMVS CLHILSHSLDTRTVMKSGAELVKVGFKAFFENAAEDLEKLVEMLKLGKFMQSRAQMKSVT QSINYVTVALLPILTALFEHTRTHEFDVDLLVDDVQLSCYRILMCFYSLGTGKNVFVERH LPAIGESLATLVGAMPVAFLEPDLNAHNPLSVFNTKTPRERAILSMPDTVEEMCPEMPRL DKLLKDVNDVSESGARYSDMPQVIEVVLPMLCNYLSYWWEKGPENSPPDTDCCTMVTSEH LSIILGNILKILNNNLGIDDAPWMKRIAVYSQPIICKAGADLLRTHFLPTMEKLKKKTVK VVSEEELLKADGKGDNQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSRWLKEPDADS TELFRMVAEIFILWCKSNNFKREEQNFVIQNEINNLGFLTGEGKSKMSKSGGDQERKHKR RRGEYYSIQTSLIVAALKKLLPIGLNMCTPGDQELISLAKIRYSLKDTDDEVKEHLRQNL HLQEKSDDPAVHWQLNLYKDVVVKSEEPSDSEHTVDRIQSISAAVFNLEQVEQPLRNKKC IVQKLLSKQRKRAVVACFRMAPLYNLPRYKNNNYFLNGYREVWLERAFKASSFDRLFSLL TKTPMKIVEEEEEEVAEIKPDPLHQLILHFSHNALTERSHLEVDPLYIAYADMMAKSCAE DEEEEEEEGREKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGPMVTCTLK LGISILNGGNVQVQQKMLGYLTDKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMV TEEGSINTQRGSKVLQNDEFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTTTVNIIISTV DYLLRLQESISDFYWYYSGKDVIDETGKHNFSKALSVAKQIFNSLTEYIQGPCIGNQQSL AHSRLWDAVVGFLHVFANMQMKLSQDASQIELLKELMDLQKDMVVMLLSLLEGNVVNGTI GKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDNFKEYDPECKGVISKKEFQKSMESQ KQYNQSEIEFLLSCAEADENDMFNYKEFVERFHEPAKDIGFNVAVLLTNLSEHMPHDARL ATFLDLAESVLSYFEPYLGRIEILGSAKRIERVYFEISESSREQWEKPQVKESKRQFIFD VVNEGGESEKMEMFVNFCEDTIFEMQLASQISEPDAVEQPEEEEEEEVHNILEELSGGDA AALESASAFTTACRSVKKSLSEIRQIFTIKTARKQFKKIKKLSIKELITGFFSFFWMIVI GFFKGIISLVFGFFHVIWSSMFGGGLVEGAKNIKVTDILGNMPDPTQFGIHGDVGEGDKV EAMESSGSLDKAMAPAGDATEVDVMLEMLTPKKEGGKHVEPGLGDVSELSGESSAADSKK KAAAKTAAPSESETEKADTETREKEDKPKEEAKEPAVEEKPKPRSSQPKEASPAFMSTVF AILDVYLNKILNYLARNFYNLRFLALFVCFAINFILLFYKVTGEAEEEEEDEENHWGDDD DENTLFDMDEFVLQESTGYMLPTLRFLAIFHTVISLLCLVGYYCLKVPLVVFKREKEIAR KLEFDGLYITEQPSDDDIKGQWDRLVINTPSFPNNYWDKFIKRKVINKYGDMYGAERIAE LLGLDKSALDFDPTVETVEKEASLLSWLSSIDTKYHIWKLGVVLTDNYFLYLIWYTTMSI FGHFNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFR KFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDELEDPAGDPYELYRILFDITF FFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDRTPHGFETHTL QEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14574 nt NT seq  +upstreamnt  +downstreamnt atggctgagggcggagaaggggaggatgagatccagttcttgagaactgacgatgaggtg gtgctccagagcgtggccaccatccagaaggagcatcgcaagttctgcctggccgcggag ggactcgggaaccgcctgtgttacttggaacccacctctgaagccaagtatgttcctcca gacatgtgcatttgtaactttgtgctggagcagtcgctgtcggtccgcgccctgcaggag atgctggctaacaccggaacgagcagcgaagggaaagccgaccatgaaaaatggaggtta attaaaaaggcgggtcagggaggcggacaccggaccctgctctacggtcacgccatcctc ttacgtcactccttcagtgacatgtacttgacctgtttgaagacatcaaggtctctgaca gacaagctgtcatttgatgtcggactgcaagaagattcagtaggagaagcctgctggtgg actattcatccggcgtccaagcagagatcagaaggagagaaagtccgcattggagatgat ctgattctcgtcagcgtgtccactgagagatatctgcatctctcgaactgtaacggcaac attcaggtagacgcctccttcatgcaaaccctctggaacgtccagcctacgtgttcgtca ggcagcatggctgtagggtatttgattggcgggcatgtgatgcgtctctgtcatggtcac gacgagagcttgacgatccctggagcagataagagtgaagaggagcaaagaatagtgaac tacgaggcggggaagggagcgtcaagagcccgctccctgtggagactggagcctctcagg atcagctggagcggcagccacattcgatggggccagtctttccgtctgcgtcatctctcc actggtcgctatctggccttgactgaagaccgtggtttggtcctggaggacagagagaag tgccacaccaaagccactgctttttgctttaagccatccaaggaaaaaggcgattctggc atgaagagggatattgacgggatgggagtccccgagataaagtacggtgactccgtctgt tttgtcatgcacgtggccactggactgtggctgtcctacctggcacctgatgccaaatcg tctcgtcttggtcccctgaaaagaagggcctgccttcactctgagggccacatggatgat ggtctcatcctgcagcgctgccagcatgaggagtctcgggctgctcgcatcatccgaaac accacattcctcttcaaaaacttcataaaggcactggacagcgctgcagccggagagacg aatgcggtggccgcatatgttgaagaggtgctgcagacgctgaacgatctgattgaatat ttcaagcagcccgacgtagatctagagcacgaggaaaaacaggcgaggcttcgctcactc atcaaacaacaagacctcttcaaggaggagggtatgctggccctgctctccaaatgcatt gaccggatgaacctgtatgatagtgcggcccacttcggagagatggccggggaggaagct ggtgcagcgtggaaggacatcctcaacctcctctatgaactcctggctgcactgattcgt ggaaaccggaccaactgcacccagttctcccgaaacttggactggctggtcagcaaactg gaaagaatggagtcatcatcaggaatcctagaagtcctccactgcatcttggtggaaagt ccagaagctctgaacatcattcagaaaggtcacattaaatccataatttctcttctctac aagcatggacgcaaccacaagattctggatgtgctgtgctctctgtgtgtgtgcaatggg gtggcagtgagaaccaatcagaatctgatctgtgacaacctgctgccaaaaagggacctg ctgctccagaccagactggtcaacgatgttcaaagcatgaggcccaacatcttcctgggc atcgctgaaggttcggctcagtataagaagtggtactacgagttggtcatcgaccaggtg gaccactttgtgaccggagagccgacccacctgagagtgggctgggccaacaccaaaggc tacgctccgtatcctggcggaggagagggctggggtggaaacggcgttggggatgacctt tactcctacagctttgatggacttcatctgtggtcaggtcggatccccagagccgtggcc tccattaaccagcacctgctgaactcggacgacgtggtcagttgctgcttggatctgggc gctcccagcatgtccttcaggatcaacgggcagccggtgcagggcatgtttgaggacttt aacacagacggattcttcttccccgtcgtcagcttctctgctggagtgaaagcccgtttc ctgctgggtgggcgccacggagactttaagttcctgccgccagccggttactctccgtgc tacgaagcgctcctgcccaaggagaagatgcatgtggagcctgtgaaggagtacaagcgg gaccatgacggggtccgtgacctgctgggaaccacccagttcctgtcccaggcctccttt attcccactccggttgacaccagccagattgttctgccgcctcatctggagaacatccgc gacaagttggcagaaaacatccacgaactttggggaatgaataagatcgaactgggctgg acgtatggcaaggttcgcgacgacaacaagaggcagcacccttgtcttgtggatttcagc aagctgcctgaaactgaaaagaactacaacgtgcagatgtcaagcgaaacactcaagacg ctgttggcacttggctgccatgttgcccaggttaatgttcacgctgaagaggacctgaag aaaatcaaattaccaaaagactacatgatgtctaatggatacaagcctgcgccactggaa ctctctgacatgaaactgactccaggtcaagaggttctggttgataaactggccgaaaat gcacacaacgtttgggccaaagacagaatcaaacaaggatggacctatggcatccagcag gatgtgaagagcagacgtaaccctcgcttggtgccatatgctttattggatgaacgcaca aagaaatctaacagagacagtctgagagaggccattcggacgatggttggatacggatat gacatcgaccctccagaccaggaggttgtgcatgcaatagataatcagagcatcgagaca atccgctttttccgcgtggagcaaacgtacgccgtgaagaccgggaagtggtactttgag tttgaggttctgagcggaggcgacatgagggttggctgggccaggccgggctgcaggccc gacgtggagctgggaaccgatgaccaggcctacgtctttgatggatacaggggtcgacgg atgcatgctggtagccgttactttgggcatccgtggaagaagggcgacgtggttggttgc atgatcaacatggaggacaaatccatgattttcactctgaacggagagctcctgatcacc agcaagggctctgagctcggcttcgctgactttgaaacggaggatggttttattccggtg tgcagcctcgggatgtctcagatcggccacatgaacctcggaaaggacgccagcacgttt aagtactacaccatgtgtggcctccaggaaggctttgagccctttgctgtcaacatgaac agggagataaccatgtggttcagcaagcgtttgcccacgtttttcaacgtaccccaggac cacatgcacatcgaggttaccaggattgacgggacagtggacagccccccgtgtctcaag gtcacacataagacgtttggcacccagaacagcaacagcgacatggtttactgcaggctg agcatgccggtggagttctactctgcagacagactgctggacgagtcgctgaagctcagc caacctcccaaagaagatggaagtattgactatggaagcatcacaacctactaccactca gtgagagtgtttgccggacaggaccctgccagcgtgtgggtgggctgggtcacaccagac tatcactactacagcaagaacttcagtctcagcaagacgcaaactgtcaccgtcaccctg ggagacgagcggggccgggtccacgagagtatccagaggagcaactgctacatggtctgt gcagcagatgcactcggcccgtcttcctccagccgctcaaacaccgacctggaaatcggc tgtctggtcgacttggccactggcctcgtctccttcaccgccaacggcaaagaactgcct acagcgtatcaggtggagccgaacaccaagctgttcccggctgtgttttgctgccccacc agttccaacctcttccagtttgaatttgtcaaaataaaggatgccatgccgctgtcgtca gccatgttcagaagcgagcagcggaacccggttcctcagtgtccgccgcgtctggatgtg caaaccatcgtggccgtgctttggagccggatgccaaacaccttcctgaacgtggagacg gctcgggtcagcgagcggcacggctgggtggtgcagtgtctggagcctctgcagatgatg gccgtgcacatacctgaagagaacaggtgtttggacatcatggagctgtcagagcatgaa gacctgaggaagtttcactcccacactctgaagttgtactgcgccctctgcgctctggga aacacgcgtgtggctcacgctctctgcagccacttagaccaatcacagcttctctacacc atcgacaaccagtacctgtcgggcatgctcagagaaggcttctacgacgtcctcatcagc attcatcttgagacggcgaaagaggcacggctaatgatgaacaacgaattcatcatccct gtgacggatgagacccggtccatcaagctgttcccagatgaatctaagcggcattctctt cccggagtcggcctgagcacttccctcaaaccccgagtcaacttctccccggtcggcatc atcagcaccaaacgccaccagctcctctacagcccccagatccccctgggcattctgaag gagaaagccatcagcatgctgacggaggccgtgcagggaggaggctcccacatccgagac ccggtaggcgggagcctagagtaccagttcgtccccatcctgaagctcatcggaacgctg ctcatcatgggagtgctgaccagcgacgaggtgaggctgattctcctcctcatcgagccc aacgtgtttggggaggccaaggagggagaagaggggagcgaggtggtggtggcgggggag aaagaggaggtgagcaagaacgaggagaaggctgtggaggcgggagaggaggagaccaag gagagcaaaccggccgccaaaggcctgctggagaagtccctgccggagtctgttaaacac cagatgtgcgagctgctgcactacttctgcgactgtgagctgcagcaccgcatcgaggcc atcgtctccttctccgaccgcttcgtctccaaactgcagtacaaccagaagtttcgctac aacgagctgatgcaggctttcaacatgtctgccgccgtcacggccaagaagacaaaggag tttcgctcgccgccacatgaacagatcaatattctgctgaacttcagtgcaggggaggac tgcccttgtcccgaggagatccaggatgaactcacgtctttccatgaagaattacggctg cactgtggaatccctgtggaggagcaggaggaagagcaggacacatcgattaaaggtcgg ctcctggctctgctctacaagatcaagggcccgcctcagaagacagaggagcagcccgca gagacagaacaggccgccccgaccaacctgaaggagctgatttctcagacgatcaccagc tgggcccaggagtcccacatccagaacccggagctggtccgagtcatgttcagcctgctg aggaggcagtatgacggcatcggcgaactgctgcgggccatgaagaagtcgtacaccatc agcgccgcctcggtgcaggacggcatcaacctgctggtctctctgggtcaaatcaggtcg ctgctttcagtgcgcatgggcaaggaggaggagaagctcatgatcgatgggctcggggac atcatgaacaacaaggttttctaccagcatcccaatctgatgagagttttgggaatgcat gagacggtcatggaggtcatggtcaacgtcctgggtggagacaagtcccaggagattgcc tttcccaagatggtggccagctgctgtcgatttctgtgctatttctgccgcatcagccgg cagaaccagaaggccatgtttgaccacctgagctacctgctggagaacagcagcgttgga ctggcgtctgaagcgatgcgaggctccactcctctggatgtcgcagcatcttcagtgatg gacaacaacggtctggctttagctctggaggaacctgacctggaaaaggtggtgatgtac ctggcaggatgcggcctgcagagctgtgccatactggttgccaagggttacccggacctg ggctggaaccccatagagggagagcgttacctctcattcctgagatttgtcgtcttctgc aatggtgagagcgtggaggaaaatgctaacgtggtggtgaagctgctgatccgacgtccc gagtgcttcggccctgccctgagaggcgaggggggacaaggtctgctggctgcgatgaag gaggccatcaagatctctgaggatcccgcgctggacctgcccaagagcccggctggagcc accgcagggtctggtgaagaggaaggagaagttatccacatgggcaacgccatcatgtcc ttctactccgccctcatcgacctgctgggacgctgcgctccagagatgcatcttatcaat gcagggaaaggtgaagcgttgcgtatcagagccatcctgcgctctctggttcccacgtca gacctggtgggcatcatcagcatccccctcaagatgcctgtgattaacaaagacggatcc gtgacagaacccgacatgtcggcctgcttctgcccggaccacaaggcccccatggtgctt ttcctggacagagtttacggcattgaggaccagagtttcctgctgcagatgctggaagtc gggttcctgccggacctcaaggcctcggcgtctctggacacggaagtactgagcaccacg gagacggcgctggccatgaatcgctacatcggttcggctctgcttcctctgctgacccgc tgcgccgctctgttcggcaacacggagcactacgcacatctagtcgactccacgctggag accatctatcggctgtccaaaggtcgctcgctcactaaagcccagcgggacgccatcgag gagtgtctgctggccatctgcaagcatcttcgaccatccatgatgcagcagctgctcagg cgcctcgtcttcgatgttcctctgctcactgaatactgcaagatgcctctccggctgctg accaaccactatgagcagaactggaagtactactgcctgccgtctgggatgggcggcttc ggcatggcctctgaggaagagctgctgctcacaaagaaactcttctggggaatttttgac tctctttctcagaagaaatatgattctgagctgtttaaaatggccaagtcgtgcctgtgt gccattgctggagctttgcctccagacttcgtggacaccagcttaggggcgacggtggag aagcaggagtcggtggatgcacagggaaactttgagcccaaacccatcaacactgccaac atctcccttcctgaaaaacttgactacattgctaataagtatgcagagcattcccacgac aagtgggcttcagagaagatgtcggctggctggaaacacggagacagtttggacgagcag gccaaagcccatccgctgctgaagccgtataaatctttaagtgagaaggagagggagacg taccgctggcctgtgaaagagtccctgaagagcatgctggcgatgaactggaacattgag aggaccaaggagggagaagccatgttccagcagcgagagagtgaaaaacagaggaagctc tcagaaactcagtctaacggattcagtcctgctccgatggacctgcacaatgtcactttg tcccgagagttacagagtatggtggaagtggttgcagaaaattaccacaacatctgggct aagaagaagaagtcagaacttctgagtaaaggaggagggttggctcacccgctgcttgtt ccctatgataccctgactgctaaggagaagtacagagacaaagaaaaggcccaagagctc ttcaagttcctgcagataagtggctatgctatcacaagaggtctgaaggacatggagcag gactcgtcatccatggaaaaacgttttgcctacaagttcctaaagaggctgctgaagaat atcgactctgctcaggagtttatcgcccatctggaggcgatggccaccagtgggaaaact gacaagtccccacatgaccaggagatcaagttctttgcaaaggttttacttccattgatt gatcagacatttaagaaccactgcctttacttcctgtccacacccaacaagaacctgagc agctgtggttgcgcctccaacaaggagaaggagatggtcaccagcctgttctgtaagatg gcagctcttgttagacacaggatttctctctttggaagtgactctgcgatcatggtgagc tgtcttcacatcctgtcccactcactcgacacgagaacagtgatgaaatccggcgcagag ctggtcaaagtcggcttcaaggccttctttgagaacgcggcggaggacttggagaagctg gtggagatgctgaagctggggaagttcatgcagtcgcgcgcacagatgaagagcgtcact cagagcatcaactatgtgaccgtggccctgctgcccatcctcactgccctgtttgaacac accaggacgcacgagtttgacgtggacctgctcgtggatgatgtgcagctgtcctgctac cgaatcctgatgtgtttctacagcctgggaaccggaaagaatgtctttgtggagaggcat ctgccagcgattggggagagtctggcgaccttggtgggagcgatgccggtggcgttcctg gagcctgatcttaacgcccacaacccactttcagttttcaacaccaagacgccccgagag cgagccatcctgagcatgcccgacacggtggaggagatgtgtccagaaatgcctcgcctc gacaagctgctcaaggacgtcaatgacgtgtcggagtccggcgctcgctacagtgacatg ccacaggtcattgaggtcgtcctccccatgctgtgcaactacttgtcctactggtgggag aaaggcccggagaactcgccgccggacaccgactgctgcaccatggtgacgtctgaacac ctgagcatcattctgggaaacatcctgaagatcctcaacaacaacctgggcattgatgac gctccctggatgaagaggattgcagtttactcgcagccaatcatctgcaaagctggagct gatttgttgagaacccactttctgcccacaatggagaaactgaagaagaagacagtgaag gttgtgtctgaggaggagctgctgaaggccgatgggaaaggagacaaccaggaagcagag ctgctcatcctggacgagttcgcggtgctctgcagggacctctacgctttctaccccatg ctcatccgctacgtggacaacaacaggtccaggtggcttaaggagccggatgcagactcc actgagctcttcaggatggtggctgagattttcatcctctggtgcaaatccaacaacttc aagcgtgaggagcaaaactttgtgattcagaacgagatcaacaatctgggcttcctgacc ggggagggcaagtccaagatgtccaagtctggtggagaccaggagcggaaacataaacgg cgccgcggtgaatattactccatccagacgtctctgatcgtagctgcgctcaagaagctg ctgcccatcggcttgaacatgtgcacaccgggagaccaggagctcatctctttggcaaag attcgctacagcctgaaagacacggacgatgaggtgaaagagcatttgcgtcagaacctc cacctgcaggaaaagtctgatgatccagcagttcactggcagctgaacctttataaagac gtagtggtgaaatcggaggagccgtcggattcggagcacacggtggacagaatccagagc atctctgcagccgtcttcaatttggagcaggtggaacagcctctgaggaacaagaagtgc atcgtccagaagctgctgtccaagcagcgtaagcgagccgtcgttgcttgtttccgcatg gctccactctacaacttacccagatacaaaaataataattacttcctgaatggctatcgg gaggtttggctggaaagggcgttcaaagcctccagctttgaccgcctgttctccctgctg acgaaaacaccgatgaagatcgtggaggaagaggaggaggaggtggctgagatcaagccg gatccgctccaccagctcatcctccacttcagccacaacgctctgacagagagaagccac ctggaagttgatcctttatatattgcatatgcagacatgatggcaaagagctgtgcagag gatgaggaggaagaggaagaagaagggcgggaaaagacttttgaggaaaaggagatggag aagcagaagatcctgtatcagcaggcgaggctgcacgcgcgtggggctgcagagatggtg ctgcagatgatcagcgccagcaaaggtcgtctgggccccatggtgacctgcaccctcaaa ctgggcatctccatcctaaatggaggcaacgtgcaagttcaacagaaaatgctcggttac ttgacggacaaaagagacgcaggctttttcaagagtctgtcaggactgatgcagtcttgc agtgtcctggatctgaatgcatttgagaggcaaaacaaggcagaaggacttggcatggtg acggaagaaggttcaatcaacactcagcggggctccaaggtgcttcagaacgacgaattc accaaagatctgttccgctttttgcaacttctctgtgagggacacaacggagatttccag aacttcctgagaacccaaactggaaacacgaccacagtgaacatcatcatcagcactgtg gactacctgctccgcctccaggaatcgatcagtgatttttactggtattattctgggaaa gatgtaattgatgaaactgggaagcacaacttctccaaagctttatctgtagccaagcag atttttaactcgctcactgagtacattcaggggccttgcattggaaaccagcagagttta gctcacagcagactgtgggatgcagtcgtcggcttcctgcatgtgtttgcaaacatgcaa atgaagctttcacaggatgccagtcagattgagttgttgaaggaactgatggatttacag aaggacatggttgtcatgctgctgtctctccttgagggaaacgtggtgaacgggacaatc gggaagcagatggtcgacaccctggtggagtcttccagtaacgtggagatgatcctgaaa ttcttcgacatgttcctcaaactgaaagacctcaccacgtccgacaactttaaggagtac gacccggaatgcaaaggcgtcatttccaagaaggagttccagaagtcgatggagagccag aagcagtacaaccagtcagaaatcgagttcctgctgtcgtgcgcggaggccgacgagaac gacatgttcaactacaaggagtttgtggagcgattccacgagccggccaaggacatcggg ttcaacgtggccgtgctgctgaccaacctgtccgaacacatgccgcacgacgcccggctc gccaccttcctggacctggccgaaagcgtcctcagctacttcgagccgtacctggggcgc atcgagatcctgggcagcgccaagcgaatcgaacgcgtttacttcgagatcagcgagtcg agccgcgagcagtgggaaaagccgcaggtgaaggagtccaagcggcagttcatctttgac gtggtgaacgagggaggagagagcgagaagatggagatgtttgtgaacttctgcgaggac accatctttgagatgcagctggcctcgcagatctccgagccggacgccgtggagcagccg gaggaggaggaggaggaagaggtgcacaacatcctggaggagctttctgggggagacgcc gccgccctggagtccgcctcggcgttcaccaccgcctgtcgttcggtcaagaagagtctc tcagaaatccggcagatcttcaccattaaaacggcgcgcaagcagttcaagaaaatcaag aagctgagcatcaaggagctgatcaccggcttcttctccttcttctggatgatcgtcatc ggcttctttaaggggattatcagcctcgtgttcggtttcttccacgtcatctggtcgtcc atgttcggcggagggcttgttgaaggagccaagaacataaaggtgacggacatcctgggc aacatgccggacccgacgcagttcggcatccacggcgacgtgggggaaggagacaaagtg gaagccatggagtcgtcgggcagcttggataaagccatggctcctgcaggagacgccact gaggtggacgtgatgctggagatgctgacgcctaagaaggagggagggaaacacgtggag cccggcctgggggacgtgtcggagctgagcggggagtcctccgctgcagacagcaagaag aaagccgctgccaagacggctgctccctctgagagtgagacggaaaaagcagacacagag acccgggagaaggaggacaaaccaaaggaggaggcgaaggaaccagccgtggaggagaaa cccaaacccagatccagtcagcccaaagaggcgtctccggccttcatgtcaaccgtcttc gccattcttgacgtctatctgaataagatactgaactacctggctcgtaacttctacaac ctccgtttcctggctctgtttgtttgcttcgccatcaacttcatcctgctcttttacaag gtcactggtgaagctgaggaagaggaggaagacgaggagaaccactggggtgacgatgat gacgagaacacgctgtttgacatggacgagtttgtgctgcaggagagcaccgggtacatg ctgccgacgctgcgcttcctggccatcttccacaccgtcatctcgctgctctgcctggtt ggctactactgcctgaaggttcctctggtggtgttcaagagggagaaggagatcgccagg aagctggagttcgacggtttgtacatcactgagcagccgtccgacgacgacatcaagggc cagtgggatcgactcgtcatcaacacgccatcttttcccaacaactactgggacaagttt atcaagcgcaaggtgatcaacaaatatggcgacatgtatggagcggagcgcatcgctgag cttttgggtctggataagagcgctctggactttgaccccaccgtggagacggtggagaag gaggcgtccctgctgtcctggctgagctctattgacacaaagtaccacatctggaaacta ggagtggttttgaccgacaattacttcctgtatctcatctggtacaccaccatgtccatc tttggacacttcaacaacttcttcttcgctgcacatctgctggacatcgccatgggcttc aagacgctgcgcaccatcctgtcctccgtcactcacaacggcaagcagcttgtgctgacc gtcggtctgctggccgtggtcgtctacctctacactgtggtggccttcaacttcttcaga aagttctacaacaagagcgaggacgaagacgagcccgacatgaagtgtgacgacatgatg acgtgctacttgttccacatgtatgtgggcgtgagagccggcggaggcatcggagacgag ctggaggacccggccggagatccctacgaactctaccgcatcctgtttgacatcaccttc ttcttcttcgtcatcgtcatcctgctggccatcattcagggtttgatcatcgacgccttt ggggagctgagagaccagcaggagcaggtcaaggaggacatggagaccaaatgcttcatc tgcggcatcgggaacgactactttgatcggacgcctcacgggtttgaaactcacaccctg caagagcacaacctggccaactacctgttcttcctgatgtacctaatcaacaaggatgag actgaacacacgggtcaggagtcgtacgtgtggaagatgtaccaggagagatgctgggac ttcttccctgcaggagactgcttccgcaagcaatacgaggaccagctgggctag

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