Paenibacillus lentus: EIM92_10175
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Entry
EIM92_10175 CDS
T05914
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
plen
Paenibacillus lentus
Pathway
plen00790
Folate biosynthesis
plen01100
Metabolic pathways
plen01240
Biosynthesis of cofactors
Module
plen_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
plen00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
EIM92_10175
Enzymes [BR:
plen01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
EIM92_10175
6.3.2.17 tetrahydrofolate synthase
EIM92_10175
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AZK46488
UniProt:
A0A3S8RU57
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Position
2273954..2275336
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AA seq
460 aa
AA seq
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MGVNLSKEIQLPLASYPDAVEWINGLLPFGIRPGLERIERMMEHFGHPHRRLKFIHVAGT
NGKGSSCAFLSSTLKECGYDVGMFTSPYITKFTNRFQFNGEDIPEETLLSLSNRIAPVVN
EIAASELGSPTMFEVSTALAILYFAEVCYPDVVVWETGLGGRMDVTNLVTPIVSLITNVG
MDHTDILGDSLEEIASEKAGIIKPGVPVVSCASQSSVIAVLKETAKEKGSTLYLLGEQFY
YDGNVSGLSSQTQSIHFRGPFRAMDLELSMLGQHQCVNAAGVMMVLEVLRQYMAFVLEDE
QVRVGFKNAFWAGRLEQVAEQPRIILDGAHNPEGAEALTRSLSEAFSYRKLNLMMGMLDN
KHHREYLEHILPIVDTLILTEPDFRKKMDADSLYQLVEELRGDIAKADLEVIVERDWKSA
LALLQARTEREDLGVVTGTLYMISDVRATLLHHTDSEKGW
NT seq
1383 nt
NT seq
+upstream
nt +downstream
nt
atgggggttaatctttcgaaggagattcaactgccgcttgcaagctatccagatgcggtt
gaatggattaacggtttattaccgtttggcatccgtccgggattagagcggattgaacgg
atgatggagcattttggtcacccgcatcgaagacttaagttcatacatgttgcaggaacg
aacggtaaaggctcctcctgtgcttttttaagttcaacgctcaaggaatgcggatatgat
gtagggatgttcacttccccttacattacgaagtttacgaacagattccaattcaatgga
gaggacataccggaggagacactgctcagcttgtccaaccggattgctcccgttgtgaat
gagatcgctgccagtgaattgggatctcctacaatgtttgaagtgagtacagcacttgcg
attctttattttgcggaagtatgctatcccgatgttgtagtatgggagaccggactcggg
ggtagaatggatgtaacgaacctggtcacgccgattgtgtcactgattacgaatgtcggc
atggatcacacggatattttgggcgactctctggaggaaatcgcttctgaaaaagcaggc
attatcaaaccgggcgttccggtagtaagctgtgccagccagtcttctgttattgctgtt
ttgaaagagacagctaaagagaaaggctcgacgctctatttgctaggtgagcagttttac
tacgatggcaacgttagtggcttaagcagtcaaacccagagcattcattttcgcgggccg
ttccgtgcgatggatttagagctttcgatgttaggccagcatcaatgcgtaaatgcggca
ggggtaatgatggtactcgaggttttacgccaatacatggcctttgttcttgaggatgag
caggtgcgggtcggattcaaaaatgctttttgggcaggacggcttgagcaagtagctgag
cagccgcgaatcatactcgatggggcccataatccggagggtgcagaagcgctcacgaga
agcctttcggaagcatttagctaccgaaagctgaatttgatgatggggatgctggataac
aagcatcatcgtgaatacttggagcatatattaccaatagtggatacgcttattctgacc
gagcccgattttcgcaagaaaatggatgcggattcgctgtatcagctcgtggaggaattg
cgcggagatatagcgaaggcggatcttgaagtcattgtggagcgtgattggaaaagtgcg
ctggcactgcttcaagcacggacggaacgggaggatcttggggtagttacaggtacgctc
tatatgatttcggacgtgcgggcaacccttttgcatcataccgattctgaaaaaggctgg
tga
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