Peromyscus leucopus (white-footed mouse): 114682573
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Entry
114682573 CDS
T07241
Symbol
Top3a
Name
(RefSeq) DNA topoisomerase 3-alpha isoform X1
KO
K03165
DNA topoisomerase III [EC:
5.6.2.1
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu03440
Homologous recombination
pleu03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
114682573 (Top3a)
03460 Fanconi anemia pathway
114682573 (Top3a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pleu03032
]
114682573 (Top3a)
03400 DNA repair and recombination proteins [BR:
pleu03400
]
114682573 (Top3a)
Enzymes [BR:
pleu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
114682573 (Top3a)
DNA replication proteins [BR:
pleu03032
]
Eukaryotic type
DNA Topoisomerases
114682573 (Top3a)
DNA repair and recombination proteins [BR:
pleu03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Bloom's syndrome complex (BTR)
114682573 (Top3a)
FA (Fanconi anemia) pathway
114682573 (Top3a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_GRF
Toprim
Zn_ribbon_Top1
Zn_ribbon_GRF_2
zf-C2H2_10
Motif
Other DBs
NCBI-GeneID:
114682573
NCBI-ProteinID:
XP_028712351
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All DBs
Position
8b:complement(43381952..43445682)
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AA seq
973 aa
AA seq
DB search
MEVAFRGVRKVLCVAEKNDAAKGIADLLSNGRMRRKEGFSKFNKIYEFDYHLYGQNVTMI
MTSVSGHLLAHDFQMKFRKWHSCNPLVLFEAEIEKYCPENFIDIKRTLERETQHCQALVI
WTDCDREGENIGFEIIHVCKAVKPNLQVLRARFSEITPRAVRAACENLTEPDQRVSDAVD
VRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPE
VFHRIKVTHDHKDGTVEFNWKRYRLFNHTACLVLYQLCMEDPTATVVEVRSKPKSKWRPQ
ALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPKDLNLVALVEQQTL
DPHWGGFAQNILERGGPTPRNGCKSDQAHPPIHPTKYTSGLQGDERRLYEFIVRHFLACC
SQDAQGQETTVEIDIAQERFVAHGLVILARNYLDVYPYDHWSDKLLPVYEQGFRFQPSTV
EMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTSDKRFLPGHLG
MGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKKDKFEVLRQQVQKYKQVFIEAVAKAK
KLDQALSQYLGEGAEMAQQEEIYPAMPEPVRKCPQCNKDMVLKTKKSGGFYLSCTGFPEC
RTAVWFPDSVLEASRDSSVCSICQPPPVYRLKLKFKRGSLPPTMPLEFVGCIGGCDETLK
EIFGLRFSRGPPRASQPSGHLQASQALNRMDSSQHSLSQPLVNRHTGPSKAMSQTFPPST
AAGESNSVTCNCGQEAVLLTVRKPGPNQGRHFYKCGGGSCNFFLWADSSHPPSSASGPSG
NSGRYPSALGIGADGFGSLGGDSDGTTSCLCGQPAVTRTVQKDGPNKGRQFHTCAKPREQ
QCGFFQWVDENVAPGSFAAPPWPGGRGRGQRPEAANKRLRAGSSDAGSTTKKPRKCSLCH
QPGHTRPFCPQNR
NT seq
2922 nt
NT seq
+upstream
nt +downstream
nt
atggaagtggccttccgaggagtacgaaaagttctctgtgtggcggagaaaaacgacgct
gccaaggggatcgccgacttgctgtccaatggtcgtatgcggcggaaagaaggcttttct
aaattcaacaagatttatgaatttgactatcatctgtatggacagaatgttactatgata
atgacttcagtctctggacatttgctggctcatgatttccagatgaagtttcggaaatgg
cacagctgcaaccccctagtcctctttgaagcagaaattgaaaagtactgcccagaaaat
tttatagacatcaagaggactctggaacgagagacccagcattgtcaggcactggtgatc
tggactgactgtgacagagaaggtgaaaacatcggatttgagattatccatgtatgcaag
gctgtcaagcccaatctacaggtgttgagagcccgtttctctgagatcacgccccgcgcc
gtcagggcagcctgtgaaaacctaactgagcctgaccagagagtaagtgatgccgtggac
gtgaggcaagagctggacctgaggatcggcgctgccttcacacggttccagaccctgcgg
ctccagcggattttccctgaggttctggcagagcagctcatcagctatggcagttgccag
ttcccaacgctggggtttgtggtggagaggttcaaagccattcaggcttttgtgccagaa
gtcttccacagaattaaagtaactcatgaccacaaagatgggaccgtggagttcaactgg
aaaagataccgtctctttaaccacacagcctgtcttgtcctttatcagctctgtatggag
gatcccacagcaactgtggtcgaggtcaggtctaagccaaagagcaagtggagacctcaa
gctttggacactgtggagctggagaagctggcttctcggaaattgagaataaatgctaaa
gaaaccatgaggattgcagaaaagctctatacacaagggtacatcagctacccccgaaca
gaaacaaacatcttccccaaagacttaaacctggttgccttggtggaacagcaaaccctg
gacccacactggggaggatttgctcagaacattctagagcgaggtggccccactccacga
aatgggtgcaaatctgatcaagctcaccctcccattcaccccaccaaatacaccagtggc
ttgcagggagatgaacggcgactatatgagttcatcgttcgccatttcctggcttgctgc
tcccaggatgcgcaggggcaagagactaccgtagagattgacattgctcaggaacgcttc
gtagcccacggccttgtgattctggcccgtaactacctggatgtgtatccctatgatcac
tggagtgacaagctcctccccgtctatgagcaaggcttccgctttcagcccagcactgtg
gaaatggtagatggggagaccagcccaccccagctgcttaccgaggctgacctcattgcc
ctcatggagaagcatggtatcggtactgatgccactcatgcagaacacattgaaaccatc
aaagcccggatgtatgtgggactcacctcagacaagcggttcctccctgggcacctgggc
atgggacttgtggaaggttacgattccatgggctatgagatgtccaagcctgacctccgt
gccgagctggaagctgatctcaagctgatctgtgagggcaagaaggataagtttgaggtt
ctaaggcagcaagtgcagaaatacaagcaggttttcatcgaagcagtggctaaggcaaag
aaattggatcaggccttatctcagtatttaggagaaggagcagagatggcccagcaagaa
gagatctacccagccatgccagagcctgttcgaaagtgcccacagtgcaacaaggatatg
gtccttaagaccaagaagagtggtgggttctaccttagctgcacggggttcccagaatgt
cggacagctgtgtggtttcctgactcggtgctggaggccagcagggacagcagtgtgtgt
tccatttgtcagccaccccctgtgtacaggttgaagttgaagtttaagcgtggtagcctt
cccccaaccatgcccctggagtttgttggctgcataggtggatgtgatgagactctgaag
gaaatcttcggcctgcgattttcacggggccccccaagagcttcccagccctctggccac
ctgcaggccagccaggccctcaaccggatggacagcagccagcatagcctctctcaacct
ctggtcaacagacatactggaccttccaaggcaatgagccaaaccttcccaccatccact
gctgccggtgagagcaactctgtgacctgcaattgtggccaggaggctgtgctgctcacc
gtccgcaagcccggccccaaccagggccggcacttctataagtgcggtggtggcagctgc
aacttcttcctgtgggctgacagcagccatccccccagctctgcatcaggaccctcgggc
aactccgggcgatacccatcagccttaggcatcggcgcggatggcttcggcagccttggc
ggggacagtgatggaactacgtcctgcctgtgcgggcagcctgctgtcacacggactgtg
cagaaggatggacccaacaaaggacgccagttccacacctgtgccaagccgcgagagcag
cagtgtggcttcttccagtgggtggatgagaacgtggccccagggagttttgcagccccg
ccatggccaggaggcagaggaagaggccagagaccagaggctgcaaacaaaagactaaga
gctggttcctcagatgcaggctctacaacaaaaaagccccggaaatgtagcctttgccac
caacctggacacacccgccccttttgtcctcagaacagatga
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