Peromyscus leucopus (white-footed mouse): 114683779
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Entry
114683779 CDS
T07241
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00010
Glycolysis / Gluconeogenesis
pleu00020
Citrate cycle (TCA cycle)
pleu00620
Pyruvate metabolism
pleu00785
Lipoic acid metabolism
pleu01100
Metabolic pathways
pleu01200
Carbon metabolism
pleu01210
2-Oxocarboxylic acid metabolism
pleu04066
HIF-1 signaling pathway
pleu04922
Glucagon signaling pathway
pleu05230
Central carbon metabolism in cancer
pleu05415
Diabetic cardiomyopathy
Module
pleu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
114683779
00020 Citrate cycle (TCA cycle)
114683779
00620 Pyruvate metabolism
114683779
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
114683779
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
114683779
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
114683779
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
114683779
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
114683779
Enzymes [BR:
pleu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
114683779
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
tSH3-B_UBE2O
DUF1186
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
114683779
NCBI-ProteinID:
XP_028713939
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All DBs
Position
6:complement(111990353..111991988)
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AA seq
391 aa
AA seq
DB search
MRKMLTAVVSHVFSEAVQKPALRGVLASVNFSNDATCEIKKCDLYRLEKGPPTSTVLTRE
EALKYYRSMQVIRRMEMKSDQMYKQKLIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYTRGLSVKSILAELTGRRGGCAKGKGGSMHMYCKRFYGGNGIVGAQVPLGAGVAF
ACKYLGNGEICLALYGDGAANQGQVAEAYNISALWKLPCVFICENNRYGMGTAIERAAAS
TDYHKRGNFIPGLRVNGMDILCVREATKFAADHCRSGKGPILMELQTYRYHGHSMSDPGV
SYRSREEVQNMRSKSDPIMLLRERMINNNLSNIEELKEIDADVRKEVEEAAQFATTDPEP
ALEELAHHLYYRNPPFEVRGTNKWIKYKSIS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctgactgctgtggtgtcccacgtgttttccgaagcggtccagaagccg
gctctcagaggggtgctggcctccgttaacttctccaacgacgccacctgtgaaattaag
aaatgcgacctgtaccggctggaaaagggcccccccacctccaccgtgctcaccagagag
gaggccctcaaatactaccggagcatgcaggtgattcggcgcatggagatgaagtctgac
cagatgtataagcagaagttgattcgtggtttctgtcacctgtgtgatgggcaggaagcc
tgctgcgtggggctggaggcagggataaatcccacggatcatgtcatcacgtcctacagg
gctcatggcttgtgctacacacggggcctgtcggtcaaatccattctcgcagagctgact
ggacgcagaggaggctgtgctaaaggcaaaggaggctctatgcacatgtactgcaagagg
ttctacgggggcaatggcattgttggagcacaggtgcccttgggagccggtgttgctttc
gcctgtaaatacctgggaaatggtgagatctgcttggccttgtatggcgatggtgcagct
aaccaggggcaggtagccgaagcttacaatatatcagccttgtggaaattaccgtgtgtt
ttcatctgtgagaataaccgctatggaatggggacagccattgagagagcagcagccagc
actgattaccacaagagaggcaattttatccctggactgagggtgaatggaatggatatt
ctctgtgtccgcgaggcaaccaagtttgcagctgatcactgcagatctggaaaggggccc
attttgatggaactgcagacctaccgttatcatggacatagtatgagtgatccaggggtc
agttaccgttcacgagaagaagttcaaaacatgcgaagtaagagtgatcctattatgctt
ctccgagagagaatgataaacaacaacctcagcaacattgaagaattgaaggaaatcgat
gcagatgtgagaaaagaagtcgaggaagcagcccagtttgctacaactgatccagaacca
gctttggaagaattagcccatcatctctactaccgaaatccaccatttgaagttcgtggt
acaaataagtggatcaagtataagtccatcagttag
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