Peromyscus leucopus (white-footed mouse): 114685294
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Entry
114685294 CDS
T07241
Symbol
Bckdha
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00280
Valine, leucine and isoleucine degradation
pleu00640
Propanoate metabolism
pleu00785
Lipoic acid metabolism
pleu01100
Metabolic pathways
pleu01210
2-Oxocarboxylic acid metabolism
Module
pleu_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
114685294 (Bckdha)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
114685294 (Bckdha)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
114685294 (Bckdha)
Enzymes [BR:
pleu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
114685294 (Bckdha)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
PolC_DP2_central
Motif
Other DBs
NCBI-GeneID:
114685294
NCBI-ProteinID:
XP_028715710
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Position
1:169545260..169574566
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AA seq
445 aa
AA seq
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MAVAMSLAKIWRPSRVLGQAALLLLRRPGVRGLARSQPSRQQQQFPSLDDKPQFPGASAE
FVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPQLPQEEVLKLYRSMTLLNTMDRILY
ESQRQGRISFYMTNYGEEGTHVGSAAALDRTDLVFGQYREAGVLMYRDYPLELFMAQCYG
NVNDPGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRIVICYFGEGA
ASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGILSIRVDG
NDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHP
ISRLRLYLLSQGWWDEEQEKAWRKQSRKKVMEAFEQAERKLKPNPNLLFSDVYQEMPAQL
RRQQESLARHLQTYGEHYPLDHFDK
NT seq
1338 nt
NT seq
+upstream
nt +downstream
nt
atggcggtagcgatgtctttggccaagatctggaggccgagccgtgtcctgggccaggca
gctctcctgctgctgcggcggcctggggttcggggcttggctagatcccaacccagcagg
cagcagcagcagttcccatccctggacgacaagccccagttcccaggggcctcggcggag
tttgtagacaagcttgagttcatccaacccaatgtcatctctggtatccccatctaccgt
gtcatggaccgccagggccagatcatcaaccccagtgaagacccccagctgccccaggag
gaggtactgaagttatacaggagcatgacgctgctcaacaccatggaccgaattctctat
gagtcccaacggcagggccggatctccttctacatgaccaactatggtgaggaagggaca
catgtggggagtgccgccgccctggaccgtacagacctggtgtttggccagtaccgggag
gcaggtgtgctcatgtaccgggactaccctctggaactgttcatggcccagtgctacggc
aacgtgaatgacccaggcaaggggcgccagatgcccgttcactatggctgcaaggagcgc
cacttcgtcaccatctcctctccactggccacgcagatccctcaggcggtgggggcagcc
tatgctgccaagcgggccaatgccaaccggatcgtgatctgttacttcggtgagggggca
gccagtgaaggggatgcccatgccggcttcaactttgctgccaccctggagtgtcctatc
atcttcttctgccggaacaatggctatgccatctccacaccaacctccgagcagtaccgc
ggggatggcattgcggctcgaggccctgggtatggcatcctgtcaatccgtgtggacggc
aacgatgtgtttgcagtgtacaatgccaccaaggaggcccgacggcgggccgtggctgag
aaccaacccttcctcattgaggccatgacctacaggattgggcaccacagcaccagtgac
gacagctcagcataccgttcagtggacgaggtcaattactgggacaagcaggaccaccca
atctccaggctgaggctatatctgctgagccagggttggtgggatgaggagcaggagaag
gcctggaggaagcagtcacggaagaaggtgatggaggcctttgaacaggctgagcggaag
ctaaagcccaacccaaacctgctcttctccgacgtgtaccaggagatgcccgcccagctc
cgcaggcagcaggagtccctggcacgacatctgcagacctatggggagcactaccccctg
gaccactttgacaagtga
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