Peromyscus leucopus (white-footed mouse): 114686356
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Entry
114686356 CDS
T07241
Symbol
Hsd17b8
Name
(RefSeq) estradiol 17-beta-dehydrogenase 8
KO
K13370
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:
1.1.1.62
1.1.1.239
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00061
Fatty acid biosynthesis
pleu00140
Steroid hormone biosynthesis
pleu01100
Metabolic pathways
pleu01212
Fatty acid metabolism
Module
pleu_M00873
Fatty acid biosynthesis in mitochondria, animals
pleu_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
114686356 (Hsd17b8)
00140 Steroid hormone biosynthesis
114686356 (Hsd17b8)
Enzymes [BR:
pleu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
114686356 (Hsd17b8)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
114686356 (Hsd17b8)
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Motif
Pfam:
adh_short_C2
adh_short
KR
Epimerase
RmlD_sub_bind
RNA_pol_Rpb1_4
Motif
Other DBs
NCBI-GeneID:
114686356
NCBI-ProteinID:
XP_028716852
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Position
16_21:9032648..9034599
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AA seq
259 aa
AA seq
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MASQLRLRSALALVTGAGSGIGRAISVRLAEEGAAVAACDLDGAAAQDTVRLLGGPGRED
GAPRGKHAAFQADVSRAPAARRLLEQVQACFSRPPSVVVSCAGITRDEFLLHMSEEDWDR
VIAVNLKGTFLVTQAAAQALVSSGCRGSIINISSIIGKVGNIGQTNYASSKAGVIGLTQT
AARELGRHGIRCNSVLPGFIATPMTQKMPEKVKDKVTAMIPLGHMGDPEDVADVVAFLAS
EDSGYITGASVEVTGGLFM
NT seq
780 nt
NT seq
+upstream
nt +downstream
nt
atggcgtctcagctccggctccgctccgcgctggccctggtcacaggtgcgggcagcggc
atcggccgtgcgatcagcgtgcgcctggcggaagagggcgccgccgtggccgcctgcgac
ctggacggggcagccgcacaggacaccgtgcggctgctgggcggcccgggccgcgaggac
ggggcgccgcgcgggaagcacgccgccttccaggcggacgtgtcgcgggcccccgcggcc
aggcgcctgctggagcaagtgcaggcctgcttttctcgcccgccatctgtcgttgtgtcc
tgtgcgggcatcacacgcgatgagtttctgctccacatgtcagaggaagactgggacaga
gtcatagctgtcaacctcaagggcaccttcctggtcactcaggctgcagcccaggctttg
gtgtccagcggctgtcgtggctccatcatcaacatcagtagcatcattggaaaggtcggg
aatattggacaaacaaattatgcatcctccaaagcgggagtgattgggctcacccagact
gcggcccgcgagctgggacgacatgggatccggtgtaactcagtcctcccagggttcatt
gcaacgcccatgacccagaaaatgcccgagaaagtgaaggacaaggtgactgcaatgatc
ccgttgggacacatgggggaccctgaggatgtggcagatgtggttgcgttcttggcatct
gaagacagtggatacatcacaggggcctcagtggaagtcactggaggtcttttcatgtga
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