Peromyscus leucopus (white-footed mouse): 114686509
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Entry
114686509 CDS
T07241
Symbol
Dot1l
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00310
Lysine degradation
pleu01100
Metabolic pathways
pleu05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
114686509 (Dot1l)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
114686509 (Dot1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pleu03036
]
114686509 (Dot1l)
Enzymes [BR:
pleu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
114686509 (Dot1l)
Chromosome and associated proteins [BR:
pleu03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
114686509 (Dot1l)
HMT complexes
Dot1-containing complex
114686509 (Dot1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
114686509
NCBI-ProteinID:
XP_037054080
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All DBs
Position
22:1262418..1303763
Genome browser
AA seq
1419 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVP
ESKAAATEVPADSGAEEEKSGVATVKKPSPSKARKKKLSKKGRKMAGRKRGRPKKMSAAN
AERKSKKSQSTLDLLRSPPAAPPPASPQDAYRAPPSPFYQLPPSTQLHSPNPLLVAPTPP
ALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFGHCQAQKEE
IHRLFQQKLHELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRA
RCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELLQLKSC
VPPDDALSLHLRGKGALGRELEADAGRLRLELDCAKISLPHLSSMSPELSMNGHAASYEL
CNTASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLR
RHLSQDHAGSSKAAAGEPHPRAEPTKESTLPYQSPGLSNSMKLSPQDPLPASPATSPLTS
EKGSEKGGKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPS
PVPQPRDSSSTLEKQIGASAHGAGGGAGGSRSLALAPTGFYTGSVAISGALASSPAPLAS
GVESAVFDESSGPSSLFATMGSRSTPPQHPPLLPQPRNSGPASPAHQLSASPRLSGTTQG
PLPDTSKGDLPSDPAFSDPESEAKRRIVFSIAAGSGSKQSPSTRHSPVTSGPRGDCGQSH
GQDSRKRSRRKRASAGTPSLSTGVSPKRRALPTVAGLFTQSSGSPLNLNSMVSNINQPLE
ITAISSPESSLKSSPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPGSEDEPSSAR
IERKIATISLESKSPPKTLENGVFTHAVPSASAHPFGAGVGSGAVCSSATLGLSPLQAAA
STSASSFQAAASVETRPPPPPPLLPPQHLGRPPAGPPVLHAPPPPNVALPPPPALLTSNS
EPVLLQSLASLPANKAFLPPSSAASLQPANASLSVKLASLPHKVSRPSFTVHHQPLPRLA
LAQAAPAAPQASSSGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
4260 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagaagctggagctgaggctcaagtcgccggtgggcgccgagcccgctgtctac
ccgtggccgctgccggtctacgacaagcaccacgatgctgctcatgagattattgagact
atccggtgggtctgtgaggaaatcccggatctcaagctggccatggagaactacgttctc
atcgactatgacaccaaaagtttcgaaagcatgcagaggctgtgtgacaagtacaaccga
gccatcgacagcatccaccagctgtggaagggcaccacgcagcccatgaagctgaacact
cggccctccaatgggctcctgcggcacatcctgcagcaggtgtacaaccactccgtgacc
gaccccgagaagctcaacaactacgagcccttctccccggaggtgtacggggagacctcc
ttcgacctggtcgcccagatgatcgacgagatcaagatgaccgaggacgacctgtttgta
gacctgggcagtggtgtggggcaggttgtccttcaggttgctgctgccaccaactgtaaa
catcactacggagtggagaaagcggacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaacga
ggtgacttcctctcagaggagtggagggaacggatcgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcggttcgcaaacatg
aaggaaggtggcaggatcgtctcctccaagcccttcgcccctctcaacttcaggatcaac
agcaggaacttgagtgacatcggcaccatcatgcgtgtggtggagctgtcgcccctgaag
ggctctgtgtcgtggactgggaagccggtctcctactacctgcacactattgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggagcaggaggcc
gcgcggcgacggcagcagcgggagaacaagagcaacgccaccacccccaccaaggtcccc
gagagcaaggccgcggccaccgaggtccctgcggactctggtgctgaggaagaaaagtca
ggtgtggccactgtcaaaaagccatctccctccaaagcccggaagaagaagctgagcaag
aaaggcaggaagatggctggccggaaacgcgggcggcccaagaaaatgagtgctgcaaat
gctgagcgcaagtccaagaagagccaaagcacactggacctcctgcgctccccgcctgca
gccccacccccagcctcaccccaggacgcgtacagggcgcctcctagcccattctaccag
ctacctccgagcacgcagctccactcccccaatccgctgctggtggcacccaccccgcct
gcattacagaagcttttagagtccttcaaaatccagtacctgcagttcctggcctacacg
aagaccccgcagtacaaggccaacctgcagcagctgctggaccaggagaaggagaagaac
acgcagctgctgggcaccgctcagcagctcttcggtcattgccaagcccagaaggaggag
atccacagactgttccagcagaagctgcatgagttgggcgtgaaggcgctgacctacaat
gacctaattcaggcccagaaggagatctcggcccacaaccagcagctgcgggagcagtcg
gaacagctggagaaggacaacagcgaactgcggagccagagcctgcggctgctcagggcc
cggtgcgaggagctgaggctggactggtccacgctgtctctggagaacctgcggaaagag
aagcaggccctgcggagccagatctcggagaagcagagacactgcctggagctgcagatc
agcatcgtggagctggagaagagccagcggcagcaggagctcctgcagttgaagtcctgc
gtgccgcccgacgatgccctgtccctgcatctgcgaggcaagggggccctgggccgcgag
ctggaggccgatgctgggcggttgcgtctcgagctggactgtgccaagatctccctgccg
cacctcagcagcatgagccccgagctctccatgaatggccatgccgccagctacgagctc
tgcaacacagctagtcggccctcgtccaagcagaacaccccccagtacctggcctccccc
ctggaccaggaggtcgtaccctgcacccccagccacagtggccggccccggctagaaaag
ttgtctggcctggctttgccagactatacccggttgtcccctgcgaagattgtcttgagg
cggcacctgagccaggaccatgccgggtctagcaaagccgctgccggtgagccgcaccct
cgggcggagcccaccaaggaaagcacccttccctaccagagccccggcttgtccaacagc
atgaagctcagcccccaggatccactgcctgcctccccggcgacctcgccgctcacctca
gagaagggcagtgagaagggcgggaaggagcgtgcctacagcagccacggggagacgatc
accagcctgcccgtcagcattccactcagcaccgtgcagcccaacaagctgcccgtcagc
atcccgctggctagcgtggtgctgcccagccgcgccgagagggcgaggagcactcccagc
cctgtgccacagccccgagactcctcatccacacttgaaaagcagattggtgcttctgcc
catggtgcaggaggcggtgcaggagggagcaggagcctcgccctggcgcctacaggcttc
tacactggctcggtggccatcagcggggccctggccagcagcccagcgcctctggcctct
ggagtggaatctgctgttttcgacgagtcctctggacccagcagcctctttgccaccatg
gggtctcgcagcacaccgccacagcacccccctctgctgccgcagccccgcaactccggc
cccgcctctcctgcccaccagctctcagccagtccccgcctgagtgggacgacccagggt
ccgctgcccgacaccagcaagggggatctcccttctgaccctgccttctccgacccggag
agcgaagccaagaggaggattgtgttcagcattgcagccggttccggctctaagcagtcg
ccttccaccaggcacagccccgtgacctctggcccccgtggggactgtggtcagagccat
gggcaggacagccgtaagcgcagcagacggaagcgtgcgtcagctggaacccccagcctc
agcacgggtgtgtcccccaagcgccgggctctgccaactgtcgctggcctcttcacacag
tcctcggggtctcccctcaacctcaactccatggtcagcaacatcaatcagcccctggag
atcacagccatctcatcccctgagagctccctgaagagttcccccaccccctaccaggac
cacgatcagcccccagtgctcaggaaggagcggcccctgggcccgaccaatggagcccat
tactcaccgctgacctcagatgaggagccaggctctgaggacgagcccagcagtgcccga
atcgaaagaaaaattgcaacaatctccttagaaagcaaatctcccccgaagacgctggaa
aatggtgtctttacccacgcggtgccttctgcctctgctcacccgtttggagctggtgtc
ggcagcggggctgtgtgtagcagcgccacgctgggcctgagcccgctgcaggcggcggcc
agcacctcggcttcttcctttcaggccgcggcttcggtcgagactcggccgccccctccg
cctcccctccttcctcctcagcacctgggcaggccccctgcggggcctcccgtcctccac
gcacccccccctcctaacgtggccttgcctcctccacctgcgctgctgacttctaactcg
gagccggtgcttctgcagagcctggcctccctcccggctaacaaagctttcttacccccc
tcctctgccgcctctctgcagcctgctaacgcctctctgtctgtcaagctcgcctccctc
ccacacaaggtctcccgcccctccttcacggtgcaccaccagcccctgccccggctggcc
ctggcgcaggccgcgcccgccgccccgcaggccagctcctcggggccatctgctgtgtgg
gtttcccttggcatgccgcctccttatgccgcgcacctttcgggggttaagcctcgataa
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