KEGG   Peromyscus leucopus (white-footed mouse): 114690458
Entry
114690458         CDS       T07241                                 
Symbol
Map2k6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
pleu  Peromyscus leucopus (white-footed mouse)
Pathway
pleu04010  MAPK signaling pathway
pleu04015  Rap1 signaling pathway
pleu04218  Cellular senescence
pleu04380  Osteoclast differentiation
pleu04620  Toll-like receptor signaling pathway
pleu04664  Fc epsilon RI signaling pathway
pleu04668  TNF signaling pathway
pleu04750  Inflammatory mediator regulation of TRP channels
pleu04912  GnRH signaling pathway
pleu04935  Growth hormone synthesis, secretion and action
pleu04936  Alcoholic liver disease
pleu05014  Amyotrophic lateral sclerosis
pleu05022  Pathways of neurodegeneration - multiple diseases
pleu05132  Salmonella infection
pleu05135  Yersinia infection
pleu05145  Toxoplasmosis
pleu05161  Hepatitis B
pleu05163  Human cytomegalovirus infection
pleu05167  Kaposi sarcoma-associated herpesvirus infection
pleu05169  Epstein-Barr virus infection
pleu05170  Human immunodeficiency virus 1 infection
pleu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pleu05417  Lipid and atherosclerosis
pleu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pleu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114690458 (Map2k6)
   04015 Rap1 signaling pathway
    114690458 (Map2k6)
   04668 TNF signaling pathway
    114690458 (Map2k6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    114690458 (Map2k6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    114690458 (Map2k6)
   04664 Fc epsilon RI signaling pathway
    114690458 (Map2k6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    114690458 (Map2k6)
   04935 Growth hormone synthesis, secretion and action
    114690458 (Map2k6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    114690458 (Map2k6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    114690458 (Map2k6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    114690458 (Map2k6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    114690458 (Map2k6)
   05161 Hepatitis B
    114690458 (Map2k6)
   05163 Human cytomegalovirus infection
    114690458 (Map2k6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    114690458 (Map2k6)
   05169 Epstein-Barr virus infection
    114690458 (Map2k6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    114690458 (Map2k6)
   05135 Yersinia infection
    114690458 (Map2k6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    114690458 (Map2k6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    114690458 (Map2k6)
   05022 Pathways of neurodegeneration - multiple diseases
    114690458 (Map2k6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114690458 (Map2k6)
   05418 Fluid shear stress and atherosclerosis
    114690458 (Map2k6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    114690458 (Map2k6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pleu01001]
    114690458 (Map2k6)
Enzymes [BR:pleu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     114690458 (Map2k6)
Protein kinases [BR:pleu01001]
 Serine/threonine kinases: STE group
  STE7 family
   114690458 (Map2k6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase CLP1_P Haspin_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 114690458
NCBI-ProteinID: XP_028721111
LinkDB
Position
8b:complement(81828128..81948699)
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaagattccaaaagaagccttt
gaacaacctcagaccagttccacgccacctcgagatttagactccaaggcttgcatttct
attggaaatcagaactttgaggtgaaggcagatgacctggagcctatagtggagctgggc
cgaggtgcgtacggggtggtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagttaacagccaggagcagaaacggctactgatggatctg
gacgtttccatgaggacagtggattgtccatttaccgtcaccttctatggtgcactcttc
cgggagggtgatgtgtggatatgcatggagctcatggatacgtcactagataaattctac
aaacaagttattgataaaggccaaacaattccagaggatatcttagggaagatagcagtt
tctattgtaaaagcattagaacatctacacagtaagctctctgttatccatcgagatgtc
aagccttctaatgtgctcattaatactctgggtcaagtgaagatgtgtgactttggaatc
agtggctacctggtggactctgttgctaaaacgattgatgcgggttgcaaaccatacatg
gctcctgaacgaataaacccggagctcaaccagaaggggtacagtgtgaagtctgacatt
tggagtctgggcatcaccatgattgagctggccatccttcggtttccctatgactcctgg
ggaactcccttccagcagctaaagcaagtggtagaagagccgtcgccacagctccctgca
gacaagttctccgcagagtttgtcgactttacctcacagtgcttgaagaaaaattccaaa
gaacggcccacatatccagagcttatgcaacatccatttttcaccctacacgaatccaaa
gcaacagatgtggcatcttttgtaaaactgatacttggggactaa

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