Peromyscus leucopus (white-footed mouse): 114690666
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Entry
114690666 CDS
T07241
Symbol
Fh
Name
(RefSeq) fumarate hydratase, mitochondrial
KO
K01679
fumarate hydratase, class II [EC:
4.2.1.2
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00020
Citrate cycle (TCA cycle)
pleu00620
Pyruvate metabolism
pleu01100
Metabolic pathways
pleu01200
Carbon metabolism
pleu04934
Cushing syndrome
pleu05200
Pathways in cancer
pleu05211
Renal cell carcinoma
Module
pleu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pleu_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
114690666 (Fh)
00620 Pyruvate metabolism
114690666 (Fh)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114690666 (Fh)
09162 Cancer: specific types
05211 Renal cell carcinoma
114690666 (Fh)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
114690666 (Fh)
Enzymes [BR:
pleu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.2 fumarate hydratase
114690666 (Fh)
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Gene cluster
GFIT
Motif
Pfam:
Lyase_1
FumaraseC_C
Motif
Other DBs
NCBI-GeneID:
114690666
NCBI-ProteinID:
XP_028721372
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Position
15:23351933..23377707
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AA seq
507 aa
AA seq
DB search
MYRALRLLARSRRLLRTPSAGAAVSEEAGTLRRCAPNVARMASQNSFRIEYDTFGELKVP
TDKYYGAQTVRSTMNFKIGGATERMPIPVIKAFGILKRAAAEVNQDYGLDPKIASAIMKA
ADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVNK
SQSSNDTFPTAMHIAAAVEVHEVLLPGLQKLHDALSAKSKEFMQVIKIGRTHTQDAVPLT
LGQEFSGYVQQVQYAMARIKAAMPRIYELAAGGTAVGTGLNTRVGFAEKVAAKVAALTGL
PFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEP
GSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLL
GDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKKGSTLK
ETAIELGYLTAEQFDEWVKPKDMLGPK
NT seq
1524 nt
NT seq
+upstream
nt +downstream
nt
atgtaccgagcactccgactcctcgcccgctcgcgtcgcctcctgcggaccccgtccgcc
ggtgctgccgtctcagaggaagcaggcaccctccggcggtgtgccccaaacgtcgcgcgg
atggcaagtcaaaattccttccgtatagaatatgacacctttggtgaactgaaggtccca
actgataagtattatggcgcccagaccgtgagatctacgatgaactttaaaatcggaggt
gcgacagagcgtatgccaatcccagtcattaaagcttttggcatcttgaagcgagctgct
gctgaagtaaaccaggattatggtcttgatccaaagattgctagcgcaataatgaaggcg
gcagatgaggtagctgaaggtaaactaaacgaccactttcctctggtggtgtggcagact
ggatcaggaacccagacaaacatgaacgtaaatgaagtcattagcaatagagcaattgag
atgttaggaggtgaacttggcagcaagaagcctgtgcaccccaacgatcatgttaataag
agccagagctcaaatgacacctttcccacagcaatgcacatcgccgctgccgtggaagtt
catgaggtcttgttaccaggactacagaagctgcacgatgcgctcagtgccaagtccaaa
gagtttatgcaggtcatcaaaattgggagaacgcacacgcaggacgctgttccacttact
cttgggcaggaattcagtggttacgtccagcaagtccagtatgcaatggcaagaataaaa
gctgccatgccgagaatctacgagctcgctgctggaggcacggctgtcgggacggggtta
aacaccagggtcggcttcgcagagaaggtggctgcaaaggtggccgccctgacaggcttg
ccttttgtcactgcccccaataagtttgaagccctggctgcccacgatgctctggtggag
cttagtggggccatgaacacgaccgcctgcagcctgatgaagatagccaatgatatccgc
ttcctgggttccgggcctcggtcaggtctaggagagctgatcttgcctgagaatgaacca
gggagcagcatcatgccaggaaaggtgaaccctactcaatgtgaagcgatgaccatggtt
gcagcccaagtcatggggaatcatgttgctgttactgttggaggcagcaatggacatttt
gagttgaacgtttttaaaccaatgatgattaagaatgtattacactcagccaggctgctg
ggggatgcttcagtgtctttcacggaaaactgtgtggtggggatccaggccaacacagag
aggatcaacaagctaatgaatgagtctttaatgttggtgacagctcttaatcctcatata
gggtatgacaaagcagcaaagatcgccaagacagcccacaagaaagggtcaaccttaaag
gaaacggccattgaacttggctatctcacagcagagcagtttgatgagtgggtgaaaccc
aaggacatgctgggtccaaagtga
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