Peromyscus leucopus (white-footed mouse): 114691355
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Entry
114691355 CDS
T07241
Symbol
Pde10a
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00230
Purine metabolism
pleu01100
Metabolic pathways
pleu04024
cAMP signaling pathway
pleu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
114691355 (Pde10a)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
114691355 (Pde10a)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
114691355 (Pde10a)
Enzymes [BR:
pleu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
114691355 (Pde10a)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
114691355 (Pde10a)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
114691355
NCBI-ProteinID:
XP_028722474
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Position
8a:complement(53461674..53907341)
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AA seq
1072 aa
AA seq
DB search
MASPEERFAPRPQAPLPAAGDEPGRGQVRQEPRRGEASGWSAVGLSLAPELPGCGREELA
APPPLSRSLSPTGHASPAGGPSALSALRAGGCGWVAARAPSALAFSSPIPSSSFSSSWYF
WPPPPLPPPPLVPSSSAFHLPVRLPRREGAAAAGGGGGGGDAGGGGGGGGQEAAPLSVPP
GSSHRSGGGSGGRRRLFLSPAILGLLLPARAGPRPPPPPPRLPLHPGARRTDSPGFPGAG
GGCPGLGPGSAAGGRTPWRPRGAAFPLATAWPLLFASDMEDGPSNNASCFRRLTECFLSP
SLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKNNKVEDESAPKEVSRYQDTNMQ
GVVYELNSYIEQRLDTGGDNHLLLYELSSIIRIATKADGFALYFLGECNNSLCVFTPPGI
KEGQPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLP
IVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDF
LLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEG
KPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPI
VSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTM
EKLSYHSICTSEEWQGLMRFHLPARISREIELFHFDIGPFENMWPGIFVYMIHQSCGTSC
FELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNYGLFTDLERKGLLIACLC
HDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQV
LEIIRKAIIATDLALYFGNRKQLEEMYQAGSLNLHNQSHRDRVIGLMMTACDLCSVTKLW
PVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQGQLGFYNAVAIPCYTTLT
QILPPTEPLLKACRDNLNQWEKVIRGEETALWISAPAAGKGASEKLPVKVDD
NT seq
3219 nt
NT seq
+upstream
nt +downstream
nt
atggccagcccggaggagcggttcgctccccgcccccaggccccgctgccagcggctggg
gacgagcccggtcgcggccaagtccgtcaggaaccccggcgcggagaggccagcgggtgg
agcgcagtgggcctgagcttggccccggagctgcctggctgcggccgggaggagcttgcg
gcgcccccgcccctgtcccggtccctgtctcccacaggccacgccagccccgctgggggc
cccagcgccctctccgcgctccgcgccggcggctgcggctgggtggcggcccgcgctccc
tcggcgctcgccttctcctcccctatcccctcctcctccttttcatcttcctggtacttc
tggccgccgccccccctgccccctccccctctcgtcccctcctcatctgccttccacctc
cccgtgcgtctcccgagaagggagggcgcagcggcggctggaggaggaggcggcggcggc
gatgctggcggaggaggaggaggaggaggacaagaggcagctcccttgagcgtccccccc
ggcagtagtcaccgcagcggcggtggcagcggcgggcggcggcggctcttcctctcgcct
gcgatcctaggcttgctgctcccagcccgtgccgggccccggccaccgccgccgccgccg
cggctccccctccacccgggcgcgcgccgcacagactccccgggctttccgggcgccggc
gggggctgccctggcctcggccccggctctgccgccggtggccgaactccgtggcggccc
cgcggcgccgccttccccctagccaccgcctggccgctgctcttcgcctccgacatggaa
gatggaccttctaacaatgcgagttgcttccgaaggctgaccgagtgtttcctcagcccc
agtttgacggatgagaaagtgaaggcctatctctctctccacccccaggtcttagatgag
tttgtttctgaaagtgtcagtgcggagactgtagaaaagtggctgaagagaaaaaacaac
aaagttgaagatgaatcagctcctaaggaagtcagcaggtaccaggacacgaacatgcag
ggagttgtgtacgagctgaacagctacatagagcagcgcctggacacaggtggggacaac
cacctgctcctctatgaactgagcagcatcatcaggatagccacaaaagctgacggattt
gcactgtacttccttggagagtgcaataatagtctgtgtgtgttcacacctcccggaata
aaggaaggccaaccccggcttatccctgcaggacccatcacccagggcaccaccatctct
gcttatgtggccaagtctaggaaaacgctgcttgtggaggacatccttggggacgagcga
tttccgaggggcactggcctggaatcagggactcgaatccagtctgttctctgcttgccc
atcgtcactgccatcggagacttgattggcattcttgagctgtataggcactggggtaaa
gaagccttctgtctcagccatcaggaggtggcaacggccaatcttgcttgggcttccgta
gcaatacatcaggtgcaggtgtgcagaggtctcgccaaacagaccgaactgaacgacttc
ctgctggacgtatcaaagacatactttgataacatagttgccatagactctctacttgaa
cacatcatgatatatgcaaaaaatctagtgaacgccgaccgctgcgcgctcttccaggtg
gaccacaagaacaaggagctgtactcggacctgtttgacattggggaggagaaggagggg
aagcccgtcttcaagaagaccaaggagatcagattttccattgagaaggggattgctggc
caagtagcaagaacaggggaagtcctgaacattccggatgcgtacgcagacccgcgtttt
aacagggaggtggacctgtacacgggctacaccacacggaacatcctgtgcatgcccata
gtgagccgcggcagcgtgatcggcgtggtgcagatggtgaacaagatcagtggcagtgcc
ttctccaagacggacgagaacaacttcaagatgtttgccgtcttctgtgctttggccttg
cactgtgctaacatgtaccacaggatccgccactcggagtgcatctacagggttaccatg
gagaagctgtcttaccacagcatctgcacctcagaggagtggcaaggcctgatgcgcttc
cacctgccggcgcgcatctcccgagagatcgagctattccactttgacatcggtcctttc
gagaacatgtggcctggaatctttgtctacatgatccatcagtcttgtgggacatcctgc
tttgaacttgaaaaattatgtcgttttatcatgtctgtgaagaagaactatcgacgggtt
ccttaccacaactggaaacatgcagtcacggtggcacactgcatgtatgccatacttcaa
aacaactacggcctttttacagacctcgagcgcaaaggcctgctgattgcatgtctgtgt
cacgacctggaccacaggggcttcagtaacagctacctgcagaaattcgaccaccccctg
gccgcactgtactccacctccaccatggaacagcaccacttctcccagacagtgtccatc
ctgcagctggaagggcacaacatcttctccaccctgagctccagcgagtacgagcaggtg
ctggagatcatccgcaaagccatcatcgccactgacctcgccctgtacttcgggaacagg
aagcagctggaggagatgtaccaggcagggtcgctgaacctccacaaccagtcacatcga
gaccgtgtaatcgggttgatgatgactgcctgcgatctttgctctgtgacgaagctatgg
ccagttacaaaactcacagcaaatgacatctacgcagaattctgggctgagggagatgag
atgaagaagctgggcatacaacccatcccgatgatggacagagacaagcgggacgaggtc
cctcaaggacagcttggattctacaatgccgtggctattccctgctacaccacgctgaca
cagatcctcccgcccacagagccgctgctgaaggcctgcagggataatctcaatcagtgg
gagaaggtgattcgtggggaggagacggcgttgtggatttcagcccccgcagctggcaag
ggggcatctgagaagctgcctgtgaaggttgatgactga
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