KEGG   Peromyscus leucopus (white-footed mouse): 114691777
Entry
114691777         CDS       T07241                                 
Symbol
Mapk10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
pleu  Peromyscus leucopus (white-footed mouse)
Pathway
pleu01522  Endocrine resistance
pleu04010  MAPK signaling pathway
pleu04012  ErbB signaling pathway
pleu04014  Ras signaling pathway
pleu04024  cAMP signaling pathway
pleu04068  FoxO signaling pathway
pleu04071  Sphingolipid signaling pathway
pleu04137  Mitophagy - animal
pleu04140  Autophagy - animal
pleu04141  Protein processing in endoplasmic reticulum
pleu04210  Apoptosis
pleu04215  Apoptosis - multiple species
pleu04217  Necroptosis
pleu04310  Wnt signaling pathway
pleu04380  Osteoclast differentiation
pleu04510  Focal adhesion
pleu04517  IgSF CAM signaling
pleu04519  Cadherin signaling
pleu04530  Tight junction
pleu04620  Toll-like receptor signaling pathway
pleu04621  NOD-like receptor signaling pathway
pleu04622  RIG-I-like receptor signaling pathway
pleu04625  C-type lectin receptor signaling pathway
pleu04657  IL-17 signaling pathway
pleu04658  Th1 and Th2 cell differentiation
pleu04659  Th17 cell differentiation
pleu04660  T cell receptor signaling pathway
pleu04664  Fc epsilon RI signaling pathway
pleu04668  TNF signaling pathway
pleu04722  Neurotrophin signaling pathway
pleu04723  Retrograde endocannabinoid signaling
pleu04728  Dopaminergic synapse
pleu04750  Inflammatory mediator regulation of TRP channels
pleu04910  Insulin signaling pathway
pleu04912  GnRH signaling pathway
pleu04914  Progesterone-mediated oocyte maturation
pleu04917  Prolactin signaling pathway
pleu04920  Adipocytokine signaling pathway
pleu04926  Relaxin signaling pathway
pleu04930  Type II diabetes mellitus
pleu04931  Insulin resistance
pleu04932  Non-alcoholic fatty liver disease
pleu04933  AGE-RAGE signaling pathway in diabetic complications
pleu04935  Growth hormone synthesis, secretion and action
pleu04936  Alcoholic liver disease
pleu05010  Alzheimer disease
pleu05012  Parkinson disease
pleu05016  Huntington disease
pleu05017  Spinocerebellar ataxia
pleu05020  Prion disease
pleu05022  Pathways of neurodegeneration - multiple diseases
pleu05132  Salmonella infection
pleu05133  Pertussis
pleu05135  Yersinia infection
pleu05142  Chagas disease
pleu05145  Toxoplasmosis
pleu05152  Tuberculosis
pleu05161  Hepatitis B
pleu05162  Measles
pleu05166  Human T-cell leukemia virus 1 infection
pleu05167  Kaposi sarcoma-associated herpesvirus infection
pleu05169  Epstein-Barr virus infection
pleu05170  Human immunodeficiency virus 1 infection
pleu05171  Coronavirus disease
pleu05200  Pathways in cancer
pleu05208  Chemical carcinogenesis - reactive oxygen species
pleu05210  Colorectal cancer
pleu05212  Pancreatic cancer
pleu05231  Choline metabolism in cancer
pleu05415  Diabetic cardiomyopathy
pleu05417  Lipid and atherosclerosis
pleu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pleu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    114691777 (Mapk10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114691777 (Mapk10)
   04012 ErbB signaling pathway
    114691777 (Mapk10)
   04014 Ras signaling pathway
    114691777 (Mapk10)
   04310 Wnt signaling pathway
    114691777 (Mapk10)
   04668 TNF signaling pathway
    114691777 (Mapk10)
   04068 FoxO signaling pathway
    114691777 (Mapk10)
   04071 Sphingolipid signaling pathway
    114691777 (Mapk10)
   04024 cAMP signaling pathway
    114691777 (Mapk10)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    114691777 (Mapk10)
   04519 Cadherin signaling
    114691777 (Mapk10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    114691777 (Mapk10)
   04137 Mitophagy - animal
    114691777 (Mapk10)
  09143 Cell growth and death
   04210 Apoptosis
    114691777 (Mapk10)
   04215 Apoptosis - multiple species
    114691777 (Mapk10)
   04217 Necroptosis
    114691777 (Mapk10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    114691777 (Mapk10)
   04530 Tight junction
    114691777 (Mapk10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    114691777 (Mapk10)
   04621 NOD-like receptor signaling pathway
    114691777 (Mapk10)
   04622 RIG-I-like receptor signaling pathway
    114691777 (Mapk10)
   04625 C-type lectin receptor signaling pathway
    114691777 (Mapk10)
   04660 T cell receptor signaling pathway
    114691777 (Mapk10)
   04658 Th1 and Th2 cell differentiation
    114691777 (Mapk10)
   04659 Th17 cell differentiation
    114691777 (Mapk10)
   04657 IL-17 signaling pathway
    114691777 (Mapk10)
   04664 Fc epsilon RI signaling pathway
    114691777 (Mapk10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    114691777 (Mapk10)
   04920 Adipocytokine signaling pathway
    114691777 (Mapk10)
   04912 GnRH signaling pathway
    114691777 (Mapk10)
   04914 Progesterone-mediated oocyte maturation
    114691777 (Mapk10)
   04917 Prolactin signaling pathway
    114691777 (Mapk10)
   04926 Relaxin signaling pathway
    114691777 (Mapk10)
   04935 Growth hormone synthesis, secretion and action
    114691777 (Mapk10)
  09156 Nervous system
   04728 Dopaminergic synapse
    114691777 (Mapk10)
   04723 Retrograde endocannabinoid signaling
    114691777 (Mapk10)
   04722 Neurotrophin signaling pathway
    114691777 (Mapk10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    114691777 (Mapk10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    114691777 (Mapk10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114691777 (Mapk10)
   05208 Chemical carcinogenesis - reactive oxygen species
    114691777 (Mapk10)
   05231 Choline metabolism in cancer
    114691777 (Mapk10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    114691777 (Mapk10)
   05212 Pancreatic cancer
    114691777 (Mapk10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    114691777 (Mapk10)
   05170 Human immunodeficiency virus 1 infection
    114691777 (Mapk10)
   05161 Hepatitis B
    114691777 (Mapk10)
   05171 Coronavirus disease
    114691777 (Mapk10)
   05162 Measles
    114691777 (Mapk10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    114691777 (Mapk10)
   05169 Epstein-Barr virus infection
    114691777 (Mapk10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    114691777 (Mapk10)
   05135 Yersinia infection
    114691777 (Mapk10)
   05133 Pertussis
    114691777 (Mapk10)
   05152 Tuberculosis
    114691777 (Mapk10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    114691777 (Mapk10)
   05142 Chagas disease
    114691777 (Mapk10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    114691777 (Mapk10)
   05012 Parkinson disease
    114691777 (Mapk10)
   05016 Huntington disease
    114691777 (Mapk10)
   05017 Spinocerebellar ataxia
    114691777 (Mapk10)
   05020 Prion disease
    114691777 (Mapk10)
   05022 Pathways of neurodegeneration - multiple diseases
    114691777 (Mapk10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114691777 (Mapk10)
   05418 Fluid shear stress and atherosclerosis
    114691777 (Mapk10)
   05415 Diabetic cardiomyopathy
    114691777 (Mapk10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    114691777 (Mapk10)
   04936 Alcoholic liver disease
    114691777 (Mapk10)
   04932 Non-alcoholic fatty liver disease
    114691777 (Mapk10)
   04931 Insulin resistance
    114691777 (Mapk10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    114691777 (Mapk10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    114691777 (Mapk10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pleu01001]
    114691777 (Mapk10)
Enzymes [BR:pleu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     114691777 (Mapk10)
Protein kinases [BR:pleu01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   114691777 (Mapk10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 114691777
NCBI-ProteinID: XP_028723126
LinkDB
Position
10:complement(87317280..87611528)
AA seq 464 aa
MSLHFLYYCSEPTLDVKIAFCQGFDKHVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttcttgtactactgcagtgaaccaaccttggatgtgaaaatcgccttt
tgccagggattcgataaacacgtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagtagacaaccagttctacagtgtggaagtaggagactcgaccttcaccgtt
ctcaagcgctaccagaacctgaagccgattggctctggggctcagggaatagtttgtgct
gcatacgatgctgtcctcgacagaaatgtggccattaagaagctcagccgacccttccag
aaccaaactcacgccaagagggcttaccgggagctggtcctcatgaagtgtgtgaaccat
aaaaatattattagcttattaaatgttttcacaccccagaagacgctggaggagttccaa
gacgtttacctagtgatggaactgatggatgccaacttgtgtcaggtgattcaaatggaa
ttggaccatgagcggatgtcttatttgctgtaccagatgttgtgtggcatcaagcatctc
cactctgctggaattatccacagggacttaaaacccagtaacattgtggtcaggtctgat
tgcactctgaaaattcttgacttcggactggccaggacggcaggcacaagctttatgatg
actccgtatgtggtgacacgatactacagagcccccgaggtcatcctgggaatgggctac
aaggagaacgtggatatatggtctgtgggatgcatcatgggagaaatggttcgccacaaa
atcctctttcccggaagggactatattgaccagtggaacaaagtcatcgagcagctagga
actccatgtccagaatttatgaagaaattgcagcctacagtcagaaactatgttgagaac
cggcccaagtatgctggactcaccttccccaagctgtttccagactcccttttcccagcg
gactctgagcacaataaactcaaagccagccaagccagggatttattgtcaaagatgtta
gtgatcgacccggctaagaggatatcggtggatgacgccttacagcatccctacatcaac
gtttggtatgacccagctgaagtggaggcgcctcctcctcagatatatgataaacagctg
gatgagagggagcacaccattgaagaatggaaagaacttatctacaaggaagtaatgaac
tcagaagaaaagactaaaaatggcgtagtgaaaggacagccctctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcctcgtctgtcaacgacatctcctccatgtcc
accgaccagacccttgcatcggacactgacagcagcctggaagcctcggcaggacccctg
ggttgttgcaggtga

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