KEGG   Peromyscus leucopus (white-footed mouse): 114694285
Entry
114694285         CDS       T07241                                 
Symbol
Atf4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
pleu  Peromyscus leucopus (white-footed mouse)
Pathway
pleu04010  MAPK signaling pathway
pleu04022  cGMP-PKG signaling pathway
pleu04137  Mitophagy - animal
pleu04141  Protein processing in endoplasmic reticulum
pleu04151  PI3K-Akt signaling pathway
pleu04156  Integrated stress response (ISR) signaling pathway
pleu04210  Apoptosis
pleu04211  Longevity regulating pathway
pleu04261  Adrenergic signaling in cardiomyocytes
pleu04668  TNF signaling pathway
pleu04720  Long-term potentiation
pleu04722  Neurotrophin signaling pathway
pleu04725  Cholinergic synapse
pleu04728  Dopaminergic synapse
pleu04911  Insulin secretion
pleu04912  GnRH signaling pathway
pleu04915  Estrogen signaling pathway
pleu04918  Thyroid hormone synthesis
pleu04922  Glucagon signaling pathway
pleu04925  Aldosterone synthesis and secretion
pleu04926  Relaxin signaling pathway
pleu04927  Cortisol synthesis and secretion
pleu04928  Parathyroid hormone synthesis, secretion and action
pleu04932  Non-alcoholic fatty liver disease
pleu04934  Cushing syndrome
pleu04935  Growth hormone synthesis, secretion and action
pleu05010  Alzheimer disease
pleu05012  Parkinson disease
pleu05014  Amyotrophic lateral sclerosis
pleu05020  Prion disease
pleu05022  Pathways of neurodegeneration - multiple diseases
pleu05030  Cocaine addiction
pleu05031  Amphetamine addiction
pleu05034  Alcoholism
pleu05161  Hepatitis B
pleu05163  Human cytomegalovirus infection
pleu05166  Human T-cell leukemia virus 1 infection
pleu05203  Viral carcinogenesis
pleu05207  Chemical carcinogenesis - receptor activation
pleu05215  Prostate cancer
pleu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pleu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    114694285 (Atf4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114694285 (Atf4)
   04668 TNF signaling pathway
    114694285 (Atf4)
   04022 cGMP-PKG signaling pathway
    114694285 (Atf4)
   04151 PI3K-Akt signaling pathway
    114694285 (Atf4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    114694285 (Atf4)
  09143 Cell growth and death
   04210 Apoptosis
    114694285 (Atf4)
   04156 Integrated stress response (ISR) signaling pathway
    114694285 (Atf4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    114694285 (Atf4)
   04922 Glucagon signaling pathway
    114694285 (Atf4)
   04912 GnRH signaling pathway
    114694285 (Atf4)
   04915 Estrogen signaling pathway
    114694285 (Atf4)
   04926 Relaxin signaling pathway
    114694285 (Atf4)
   04935 Growth hormone synthesis, secretion and action
    114694285 (Atf4)
   04918 Thyroid hormone synthesis
    114694285 (Atf4)
   04928 Parathyroid hormone synthesis, secretion and action
    114694285 (Atf4)
   04925 Aldosterone synthesis and secretion
    114694285 (Atf4)
   04927 Cortisol synthesis and secretion
    114694285 (Atf4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    114694285 (Atf4)
  09156 Nervous system
   04725 Cholinergic synapse
    114694285 (Atf4)
   04728 Dopaminergic synapse
    114694285 (Atf4)
   04720 Long-term potentiation
    114694285 (Atf4)
   04722 Neurotrophin signaling pathway
    114694285 (Atf4)
  09149 Aging
   04211 Longevity regulating pathway
    114694285 (Atf4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    114694285 (Atf4)
   05203 Viral carcinogenesis
    114694285 (Atf4)
  09162 Cancer: specific types
   05215 Prostate cancer
    114694285 (Atf4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    114694285 (Atf4)
   05161 Hepatitis B
    114694285 (Atf4)
   05163 Human cytomegalovirus infection
    114694285 (Atf4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    114694285 (Atf4)
   05012 Parkinson disease
    114694285 (Atf4)
   05014 Amyotrophic lateral sclerosis
    114694285 (Atf4)
   05020 Prion disease
    114694285 (Atf4)
   05022 Pathways of neurodegeneration - multiple diseases
    114694285 (Atf4)
  09165 Substance dependence
   05030 Cocaine addiction
    114694285 (Atf4)
   05031 Amphetamine addiction
    114694285 (Atf4)
   05034 Alcoholism
    114694285 (Atf4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114694285 (Atf4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    114694285 (Atf4)
   04934 Cushing syndrome
    114694285 (Atf4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pleu03000]
    114694285 (Atf4)
Transcription factors [BR:pleu03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    114694285 (Atf4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 CEP89 DUF4407 OVT1 AAA_13 BNI5_helical NOCA1_mid ZapB KIF21A DUF7194 Fez1 Asd-4 COG3_N bZIP_Maf Fib_alpha
Other DBs
NCBI-GeneID: 114694285
NCBI-ProteinID: XP_028727016
LinkDB
Position
20:37151391..37153799
AA seq 351 aa
MTEMSFLNSEVLAGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
WLAVDGLVSASDTGKEDAFSGTDWMLEKMDLKEFDFDALFRMDDLETMPDELLATLDDTC
DIFAPLVQETNKEPMTANPIGHLPESATKTDQVAPFAFLPPFPCSPGVLSSTPDHSFSLE
LGSEVDISEGDRKPDSASYITLIPQCVKDEDTPSDNDSGICMSPESYLGSPQHSPSISRG
SPSSLPSPGVPRGSPRPKPYDPPGVTLTAKVKIEKLDKKLKKMEQNKTAATRYRQKKRAE
QEALTGECKELEKKNEALKEKADSLAKEIQYLKDLIEEVRKARGKKSSLVG
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgaccgagatgagcttcctgaacagcgaagtgttggcgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaagaaagcctaggtctcttagatgactacctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcagtgcctcagacaccggcaaggaggatgctttctcc
gggacagattggatgttggagaaaatggatcttaaagagtttgactttgatgctctgttt
cgtatggatgacctggaaaccatgccagatgagcttttggccacgttggatgacacatgt
gatatttttgcccctctagtccaagagactaataaggagcccatgacagcgaacccaatt
ggccatctcccagaaagtgcaacaaaaaccgaccaggttgccccctttgcattcttgcct
cctttcccctgttccccaggggttctgtcttccactccagatcattccttcagtctagag
ctaggcagtgaagttgatatctctgaaggagatcggaagcctgactcagcttcttacatt
actctaatccctcagtgtgtaaaggatgaagacaccccctcagataatgacagtggcatc
tgtatgagccctgagtcctacctgggttctccccagcacagcccctccatctccagggga
tcaccaagcagtctgccttctccaggtgttccccgtgggtctcctcgacccaaaccttat
gacccccctggagttactttgacagctaaggtaaaaattgaaaagttggataagaagctg
aaaaaaatggagcaaaacaagacagcagccactagataccgtcagaagaagcgggctgag
caggaagccctcactggcgagtgtaaggagctagaaaagaagaacgaagccctgaaagag
aaggcagattctcttgccaaagagattcagtatctaaaagatttgatagaagaggtccgt
aaggcaagggggaagaagagttccctagtagggtag

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