Peromyscus leucopus (white-footed mouse): 114695212
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Entry
114695212 CDS
T07241
Symbol
Tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu04217
Necroptosis
pleu04380
Osteoclast differentiation
pleu04620
Toll-like receptor signaling pathway
pleu04621
NOD-like receptor signaling pathway
pleu04630
JAK-STAT signaling pathway
pleu04658
Th1 and Th2 cell differentiation
pleu04659
Th17 cell differentiation
pleu05145
Toxoplasmosis
pleu05160
Hepatitis C
pleu05161
Hepatitis B
pleu05162
Measles
pleu05164
Influenza A
pleu05165
Human papillomavirus infection
pleu05167
Kaposi sarcoma-associated herpesvirus infection
pleu05168
Herpes simplex virus 1 infection
pleu05169
Epstein-Barr virus infection
pleu05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
114695212 (Tyk2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
114695212 (Tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
114695212 (Tyk2)
04621 NOD-like receptor signaling pathway
114695212 (Tyk2)
04658 Th1 and Th2 cell differentiation
114695212 (Tyk2)
04659 Th17 cell differentiation
114695212 (Tyk2)
09158 Development and regeneration
04380 Osteoclast differentiation
114695212 (Tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
114695212 (Tyk2)
05160 Hepatitis C
114695212 (Tyk2)
05171 Coronavirus disease - COVID-19
114695212 (Tyk2)
05164 Influenza A
114695212 (Tyk2)
05162 Measles
114695212 (Tyk2)
05168 Herpes simplex virus 1 infection
114695212 (Tyk2)
05167 Kaposi sarcoma-associated herpesvirus infection
114695212 (Tyk2)
05169 Epstein-Barr virus infection
114695212 (Tyk2)
05165 Human papillomavirus infection
114695212 (Tyk2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
114695212 (Tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pleu01001
]
114695212 (Tyk2)
Enzymes [BR:
pleu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
114695212 (Tyk2)
Protein kinases [BR:
pleu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
114695212 (Tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
114695212
NCBI-ProteinID:
XP_028728270
LinkDB
All DBs
Position
7:50701284..50733879
Genome browser
AA seq
1186 aa
AA seq
DB search
MVTNMPLCRRRATPEDSSANGRNAQPLVPTGSLMVLLHWAGPDGGEPWVTFSQASLTAED
ICIHIAHKVGITPPCLNLFALYDAQAKAWLPPNHVLDTSRDVNLRLYFRMRFYFRNWHGM
NPQEPAVYRCGFPGTETSSERAEQAVQLLDSASFEYLFEQGKHEFLNDVVSLRDLSSEEE
IHHFKNESLGMAFLHLCHLALCRGVPLEEVAREVSFKNCIPRSFRQHIRQHNALTRLRLR
RVFQRFLRAFQPGHLSQQVVMVKYLATLERLAPRFGSEHIPVCHLEVLDQPERDPCYMQN
SGQSTGDPSPELATRLPTHEVLVTGTGGIQWHPLQMQESERGNNRGNPQGNRSGKKAKDP
EPGEQLAKSPGQAPWTYFCDFQDISHVVLKECHVHIHLQDNKCLLLCLRSRAEALSFVAL
VDGYFRLTADSSHYLCHEVAPPRLLTSIQNGIHGPLMDPFVQAKLWPEDGLFLIQWSTSH
LHRLILTVAHRNPAPSRGPKGLRLRKFPITQQPGAFALDGWGRSFDSVGDLRLALQGCSL
RAGDDCFPLHHCCLPRPGEISNLVIMRGSSAHTQPLNLSQLSFHRVHQDEITQLSHLGQG
TRTNVYEGLLRVGGPDEGKVDNDCPPEPGGGSGQQLRVVLKVLDPSHHNIALAFYETASL
MSQVSHMHLAFLHGVCVRGSENIIVTEFVEHGPLDVWLRRQRGRVPMTWKMVVAQQLASA
LSYLEDKNLVHGNVCGRNVLLARLGLEEGTSPFIKLSDPGVGQGALSREERVERIPWTAP
ECLSGEASSLGTATDMWGFGATLLEICFDGEAPLQGRCPSEKERFYTKQHQLPEPSCPEL
ATLTRQCLTYEPAQRPSFRTILRDLTRLQPQNLVGISAVNSDSPASDPTVFHKRYLKKIR
DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVK
YKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLMFAQQICEGMAYLHGQRYIH
RDLAARNVFLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYA
SDVWSFGVTLYELLTYCDSSQSPPTKFIELIGVTQGQMTVLRLTELLERGERLPRPDRCP
CEIYLLMKNCWEAEASFRPTFQNLVPILKTAQEKYQGQVPSVFSVC
NT seq
3561 nt
NT seq
+upstream
nt +downstream
nt
atggtaacgaacatgcctctgtgtcggcggagagccaccccggaagacagctcggccaat
ggcagaaacgctcagcccctggtgcccacaggcagcttgatggtgctgctgcactgggct
gggccggacggcggggagccctgggtcaccttcagccaggcatctctgacggcggaggac
atctgtatccacattgcacataaagtcggtatcactccaccctgcttgaatctctttgcc
ctctatgatgcgcaggccaaggcctggctgcccccaaaccacgtcctagatacatcccga
gatgtgaacctaaggctatatttccgaatgaggttttacttccggaactggcatggcatg
aatccccaggagccagctgtgtaccgatgtggtttcccagggacagagacttcctcggaa
cgtgcagagcaggctgtgcagcttttggactctgcctcctttgaatacctctttgagcag
gggaaacacgagttcctgaacgacgtggtgtctctgcgggacctgtccagtgaggaagag
atccaccactttaagaacgagagcctgggcatggccttcctgcatctctgccacctcgcc
ctctgccgtggcgtccccctggaagaggtggccagagaggtcagctttaagaactgcatc
cctcgctccttccgccagcacatccgccagcacaatgcgctcacgcgcctgcgcctccgc
agagtcttccagcgattcctgcgggcctttcagcctggccacctctcgcagcaggttgtg
atggttaagtacttggccaccctggagcggctggctcctcgatttggctcagagcacatt
ccggtgtgtcatctggaggtactggaccagcctgagagggacccctgctacatgcagaac
agtgggcaaagtactggggacccaagcccagagctggccaccaggcttcccacccacgag
gtactggtgacaggcaccggaggtatccagtggcatccactgcagatgcaggaatctgag
agaggtaacaacagagggaatccccaaggcaaccggtctgggaagaaagccaaggaccct
gagcctggagagcagctggctaagagccccgggcaagcaccctggacctacttctgtgac
ttccaggacatttcccacgtggtgctaaaggaatgtcacgtgcacatccacctgcaggac
aacaagtgcttgttgctgtgcctccgctcccgggccgaggccctgtcctttgtggccctg
gtggatggttatttccgcttgaccgctgactccagccactacctgtgccatgaggtggca
ccccccaggctcttgactagcatccagaatggcatccacgggcccctgatggatccattt
gtgcaagccaagctgtggccagaggatggcctcttcctgattcagtggagcaccagccac
cttcaccgcctgatcctcaccgtggcccatcgaaacccggctcccagccgtggcccgaag
ggcctgcgcctccgaaagttccccatcacgcagcaacccggagccttcgcgctggacggc
tggggccggtccttcgacagcgtgggggacctccggctcgccttgcagggctgctcgctt
cgggccggtgacgactgcttccccttgcaccactgttgcctgccccggccaggagaaatc
tccaacctcgtgatcatgcgcgggtctagtgcccacacccagcctcttaacctgagccag
ctcagcttccacagggttcaccaggacgagatcactcagctgtcccacttgggtcaaggc
acaaggaccaatgtttacgagggccttctaagagtgggaggccctgacgaaggcaaagtg
gacaacgactgtccccctgagcctggtgggggcagtggacagcagcttcgagtggtgctt
aaagtcctggatcccagtcaccataacattgccttggccttctacgaaacagctagcctc
atgagccaggtgtcacacatgcacctggctttcctgcacggtgtctgcgtccgtggctca
gagaatatcattgtgacagagttcgtagaacacggtcccctggatgtgtggttacggcga
cagaggggccgagtgcccatgacctggaagatggtcgtggctcagcagctggccagcgcc
ctcagctacctggaggacaagaatctggttcacgggaatgtatgtggccggaacgtcctg
ctggcccggctggggctggaggagggtactagccccttcatcaagctaagtgatcctggc
gtgggccaaggtgccctctccagggaggagcgggtggagcgcatcccatggacagctcct
gagtgcctgtctggagaggccagtagcttgggtactgccacggacatgtggggctttggt
gccaccctccttgagatctgctttgatggggaggcacccctgcagggtcgttgcccctct
gagaaagaacgattctacacaaagcagcaccagctgcccgagccctcctgcccggagctt
gccacactcacccgccagtgcctgacctacgaaccagcacagcggccgtcattccgcacc
attctgcgggacctcactaggctgcagccacagaatctagtgggcatctcggctgtgaac
tcagactcaccagcatcagaccccactgttttccacaagcgttatttgaaaaagatccgg
gatttgggcgagggccactttggcaaggtcagcctgtactgctatgacccaaccaatgat
ggcaccggcgagatggtggctgtgaaggcccttaaggagggatgtggtccccagctccgc
tcgggctggcagcgggagatcgagatcctccggaccctgtaccatgaacacatcgtcaag
tacaaaggctgctgtgaggaccaaggagagaagtctgtacagctggtcatggaatacgtc
cccctgggcagcctccgggactacctgccgcggcacagcgtcgggctggcacagctcctg
atgttcgcccagcagatctgcgagggcatggcctacctacacgggcagcgctacattcac
cgagacctggctgcgcgcaacgtgtttctggacaacgacaggctggtcaagatcggagac
tttggcctagccaaggcagtgcccgaaggccacgagtactaccgcgtgcgcgaggacggg
gacagcccggtgttctggtatgccccagaatgcctgaaggaatgcaagttttactatgca
tcagatgtctggtccttcggggtgaccctgtatgagctgctgacgtactgtgactccagt
cagagcccccccacgaaattcatcgaactcatcggcgtcacccagggccagatgaccgtg
ctgaggctcacagagttgctggaacgcggagagaggctgcctcggcctgacaggtgtccc
tgtgagatctatctcctcatgaagaactgctgggaggcagaggcctctttccggcccacc
ttccagaaccttgtgcccatcctcaagacagcccaggagaagtaccaaggccaagtgccc
tcagtgttcagcgtgtgctga
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