Peromyscus leucopus (white-footed mouse): 114696177
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Entry
114696177 CDS
T07241
Symbol
Idh2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00020
Citrate cycle (TCA cycle)
pleu00480
Glutathione metabolism
pleu01100
Metabolic pathways
pleu01200
Carbon metabolism
pleu01210
2-Oxocarboxylic acid metabolism
pleu01230
Biosynthesis of amino acids
pleu04146
Peroxisome
pleu05230
Central carbon metabolism in cancer
Module
pleu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pleu_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
114696177 (Idh2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
114696177 (Idh2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
114696177 (Idh2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
114696177 (Idh2)
Enzymes [BR:
pleu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
114696177 (Idh2)
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Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
114696177
NCBI-ProteinID:
XP_028729568
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Position
1:124525078..124546122
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AA seq
452 aa
AA seq
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MAGYLRAVHSLCRAPGPARAWAPAALTVPSWPEQPRRHYAGKRIKVEKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPHRDQTNDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVVDRAGTFKMVFTPKDGSSAKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYSI
QKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKS
TGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIKSNLDRALGKQ
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atggccggctacctgcgggccgtgcactcgctctgcagagccccgggcccggcgcgggcc
tgggcaccggccgccctgactgtccccagctggccggagcagccacggcgccactatgct
ggcaagaggatcaaggtggagaagccagtggtggagatggacggcgatgagatgacccga
atcatctggcagttcatcaaggagaagctcatcctgcctcacgtggacgtccagctcaag
tattttgacctcggccttccacaccgtgaccagaccaatgaccaggtcaccatcgactct
gcgctggccacccagaagtacagtgtggctgtcaagtgtgccacgatcacccctgatgag
gctcgtgtggaagagttcaagctgaagaaaatgtggaagagccctaatggaactatccgg
aacatccttgggggaaccgtcttcagagagccgatcatctgcaaaaacatcccccgcctt
gtccctggctggaccaagcccatcaccattggcaggcacgcccacggcgaccagtacaag
gccacagactttgtggtagatcgagctggcacgttcaagatggtcttcaccccgaaggac
ggcagcagcgccaaggagtgggaggtgtacaacttccctgccggtggcgtgggcatgggg
atgtacaacaccgacgagtccatttcgggctttgcgcacagctgcttccagtactcgatc
cagaagaagtggccgctctacttgagcaccaagaacaccattctgaaggcctatgacggg
cgtttcaaggacatcttccaggagatctttgacaagcactataagactgactttgacaag
aataagatctggtacgagcatcggctcatcgacgacatggtggcccaggtgctcaagtct
acaggtggctttgtgtgggcctgcaagaactatgacggggatgtacagtccgacatcctg
gctcaaggctttggctccctcggcctgatgacgtctgtgctggtctgtcctgatgggaag
acaattgaagctgaggccgcccatgggaccgtcacccgccattaccgagagcaccagaag
gggcgacccaccagtaccaaccccatcgccagcatctttgcctggacacggggtctagag
catcgagggaagctggatgggaaccaggacctcatcaggtttgcacagactctggagaag
gtgtgtgtagagaccgtggagagcggagctatgaccaaggacctggctggctgcatccat
ggcctcagcaatgtgaagctgaacgaacatttcctgaacacctcggacttcctggacacc
attaagagcaacctggaccgagctctgggcaagcagtag
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