Peromyscus leucopus (white-footed mouse): 114696204
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Entry
114696204 CDS
T07241
Symbol
Pde8a
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00230
Purine metabolism
pleu01100
Metabolic pathways
pleu04927
Cortisol synthesis and secretion
pleu04934
Cushing syndrome
pleu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
114696204 (Pde8a)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
114696204 (Pde8a)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
114696204 (Pde8a)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
114696204 (Pde8a)
Enzymes [BR:
pleu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
114696204 (Pde8a)
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Motif
Pfam:
PDEase_I
PDE8A_N
PAS_9
PAS
PAS_3
PAS_4
PDE8
PAS_8
Motif
Other DBs
NCBI-GeneID:
114696204
NCBI-ProteinID:
XP_028729615
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Position
1:complement(123164327..123302679)
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AA seq
821 aa
AA seq
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MGCSPSIHSSDNRAANHSVEDEGAPGPAPPRSRQRRRSTASGSGRVRLVEPQPRNGGASK
VSETDVQFGPMRFHQDQLQVLLVFTKEDNQCNGFHRACEKAGFKCTVTKEVQAVLTCFLE
KIHDIIIIDHRSPQKLDAEALCRSIRSSKLSENTVIVGVVRRGDKEEVSLMPFIAAGFTR
RYVENPNVMACYNELLQLAFGEVRSQMKLRACNSVFTALEKSQEAIEITSEDHIIQYANP
AFETTMGYQSGELIGKELAQVPINEKKGDLLDAINSCVTIGKEWQGVYHTQKKNGDNIQQ
NVKIIPVIGQGGKIRHYVSIIRVCNSSDKVETVTESVPMNSQADNQAGKHKERRKNSIDA
KAVSSKASEVSNQRRHSSLARIHSMMIEAPITKIINIINTAQENSPMPVTEALNRVLEIL
RTTELYSPQFNAEDDPHAADLVGGLISDGLRRFSGNEYVLATKNLQPSSSSIPSPISLND
IPPRIAMAIENEEQWDFDIFELEAATQKRPLIYLGLKTFARFGICEFLQCSEATLRSWFQ
IIEANYHSSNPYHNSTHSADVLHATAYFLSRNKIKETLDRMDEVAALIAAAIHDVDHPGR
TNSFLCNSGNELAVLYNDTAVLESHHAALAFQLTLENDKCNIFKNMERNDYRTLRQCIID
MVLATEMTKHFEHVNRFTNSITKPLTTQGSENTVENPEALSTPENRTLIKRMMIKCADVS
NPCRRLEHCIEWAARISEEYFSQTDEEKQLDLPVMMPVFDRNTCSIPKSQISFIDYFITD
MFDAWDTFIGLPDLMQHLDDNFRYWKGLDEKKLCSLRPPPE
NT seq
2466 nt
NT seq
+upstream
nt +downstream
nt
atgggctgctccccgagcatccacagttccgacaaccgagcggcgaaccacagcgtcgag
gacgagggcgccccgggccccgcgccgccccggtctagacagcgacgacggtcgaccgcg
tccggctccggccgcgtccggctcgtggagcctcagcctcgcaacggcggtgcctcgaag
gtatcagaaactgatgtgcaatttggcccgatgagatttcatcaagaccaacttcaggta
cttttagtgtttaccaaagaagataaccagtgtaatgggttccacagggcatgtgaaaag
gctgggtttaagtgcacagtcaccaaggaggtgcaggctgtcctcacctgtttcctggaa
aagatccatgacatcattatcatagaccatcgaagtccccagaagctggatgcagaggca
ctgtgcaggtctatcagatcatcaaaactctcggaaaacacagttattgttggtgtagta
cgcaggggggacaaagaggaggtgtctttaatgcccttcattgctgctggcttcacaagg
aggtatgtagagaaccccaacgtcatggcctgttacaatgaactgctacagttggcgttt
ggagaggtgcgatcacaaatgaaactcagggcttgtaactcagtattcactgcattagag
aaaagtcaagaagcaattgaaattacaagtgaagaccacattatacagtatgcaaaccct
gcatttgaaacaacgatgggttatcagtcaggtgaattgatagggaaggagttagcccaa
gtgcccataaatgaaaagaaaggggacttgcttgacgccataaactcgtgtgtcaccata
ggcaaggagtggcaaggagtttaccatacccaaaagaaaaatggagataatatacaacaa
aatgtgaagataatacctgtcattgggcagggcgggaaaatcagacactatgtgtccatt
atcagggtgtgcaacagcagcgataaggttgagacagtaactgagtctgtgccgatgaac
agtcaagcagataatcaggcaggcaaacataaagagaggaggaaaaattccatagatgcc
aaggcggtttcctctaaagcaagtgaagttagcaatcagagaagacactcctctctggcc
cggatacactctatgatgatcgaagcacccatcaccaagataatcaacattatcaacact
gcccaggaaaacagccccatgcctgtgacagaagccttgaaccgtgtgctggagattctg
agaaccactgagttatattcaccacagtttaatgctgaggatgaccctcacgccgccgac
ctcgttgggggcttaatatctgatggcttacgaaggttttcaggaaatgagtatgttctt
gcaaccaaaaaccttcagccatcttccagcagtattcccagccccatctccctaaatgac
atcccaccacggattgccatggccatagaaaatgaagaacagtgggactttgacatcttt
gagctggaagcggctactcaaaaaaggcctttgatttatctaggtctcaaaacatttgct
cgttttggaatctgtgaattcttacaatgctccgaggcaacgctgagatcgtggtttcaa
attattgaagccaattatcattcttctaacccctaccacaattccacacattctgcggat
gtgctccatgccactgcctacttcctttccagaaacaaaataaaggaaactttagatcgt
atggatgaggttgccgccctcatcgccgccgccattcacgacgtggaccaccctgggagg
accaactcgttcctctgcaactcggggaatgagctggccgtgctctacaacgacacagcg
gtgctggagagccaccacgccgcgctggccttccagctgaccctggaaaatgacaagtgc
aacatcttcaaaaacatggagaggaatgactaccggacactacgccagtgtattatcgac
atggtcctggccacggaaatgacgaagcactttgaacatgtcaacagatttaccaacagc
atcaccaagcccttaacaacacaagggagtgagaacactgtcgaaaatccagaagccctg
agcactccagagaaccggactctgatcaaacggatgatgatcaagtgtgccgacgtgtcc
aacccctgccggcgcctggaacactgcatcgagtgggccgcacgcatttccgaagagtat
ttttctcagactgatgaagagaagcagctggacttgcctgtgatgatgccagtttttgac
agaaacacctgcagcattcccaagtctcagatctctttcattgactacttcatcacggac
atgtttgacgcctgggacaccttcattggcctgcctgaccttatgcagcatctagacgac
aacttcaggtactggaaaggactggatgaaaagaagctgtgcagcctccgtccccctcca
gaatag
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