Peromyscus leucopus (white-footed mouse): 114697418
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Entry
114697418 CDS
T07241
Symbol
Top2b
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
114697418 (Top2b)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pleu03032
]
114697418 (Top2b)
03036 Chromosome and associated proteins [BR:
pleu03036
]
114697418 (Top2b)
Enzymes [BR:
pleu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
114697418 (Top2b)
DNA replication proteins [BR:
pleu03032
]
Eukaryotic type
DNA Topoisomerases
114697418 (Top2b)
Chromosome and associated proteins [BR:
pleu03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
114697418 (Top2b)
Centrosome formation proteins
Centriole proteins
114697418 (Top2b)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
Motif
Other DBs
NCBI-GeneID:
114697418
NCBI-ProteinID:
XP_028731504
LinkDB
All DBs
Position
9:93556079..93619885
Genome browser
AA seq
1612 aa
AA seq
DB search
MAKSSLAGADGALTWVNNAAKKEELETANKNDSSKKLSVERVYQKKTQLEHILLRPDTYI
GSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDP
ESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCN
IFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLAKFKMEKL
DKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHE
LANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSV
KPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESI
LNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVS
GLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTL
RYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYS
IPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITL
AFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDN
ERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNL
AQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDNLLKFLYD
DNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLEGLDPHPMLPN
YKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTP
ALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKK
YETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKK
DLIQMLVQRGYESDPVRAWKEAQEKAAEEEDTQNQHDDSSSDSGTPSGPDFNYILNMSLW
SLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDILAGMS
GKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASRKLLKKKKGDPDTTVVKV
EFDEEFSGTPVEGTGEETLTPSAPVNKGPKPKREKKEPGTRVRKTPTSSGKPNAKKVKKR
NPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEEEDADDDDDNNDLE
ELKVKASPIANDGEDEFVPSDGLDKDEYAFSPGKSKATPEKSSYDKKSQDFGNLFSFPSY
SQKSEDDSAKFDSNEEDTASVFAPSFGLKQTDKVPSKTVAAKKGKPPSDTAPKAKRAPKQ
KKVVETVNSDSDSEFGIPKKTPTPKGKGRGAKKRKASGSENEGDYNPGRKPAKTASKKPK
KTSFDQDSDVDIFPSDFTSEPPALPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4839 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtccagcctcgcgggtgctgatggggcgctgacctgggtgaacaatgctgca
aaaaaggaagagttggaaacagcaaacaaaaatgattcttctaagaagttatctgtcgag
agagtgtaccagaagaagacccaacttgagcatattctccttcgtcctgatacatacatt
ggatcagtagaacccttgacccagttaatgtgggtgtatgatgaagatgtaggaatgaac
tgcagagaggttacctttgttccaggcttatacaagatctttgatgaaattttggtcaat
gccgctgacaataagcagagagacaagaacatgacctgtattaaggtttctattgatcct
gaatctaatattataagcatttggaataatgggaaaggcattccagtagtagaacacaaa
gtagagaaagtttatgttcctgctttaatctttggacagcttttaacatcaagtaattat
gatgatgatgagaaaaaagttacagggggccgtaatggctatggtgcaaaactttgtaat
atttttagtacaaagtttacagtagaaacggcttgcaaagaatacaaacatagttttaag
cagacatggatgaataatatgatgaagacttctgaagccaaaattaaacattttgatggt
gaagattatacatgtataacattccaaccagatctagccaagtttaagatggaaaaactt
gacaaggacattgtggccctcatgactagaagagcatatgatttggctggttcatgtaaa
ggggtcaaggtcatgtttaatggaaagaagttgcctgtaaatggatttcgcagctatgta
gacctttatgtgaaagacaaactggatgaaactggggtagccctcaaagttattcatgaa
cttgcaaatgaaagatgggatgtttgtctcactttgagtgaaaaaggattccagcagatc
agctttgtgaatagtattgcaactacaaagggtggacggcatgtggattacgtagtagat
caagttgttggtaagctgattgaagtagttaagaaaaagaacaaagctggtgtgtcagtg
aagccgtttcaagttaaaaaccatatatgggtttttattaattgtcttattgaaaatcca
acctttgattctcaaactaaggaaaacatgactctgcagcccaaaagttttgggtccaaa
tgccaactatcagaaaaattttttaaagcagcctctaattgtggcattgtagaaagcata
ttgaactgggtgaaatttaaagctcagactcagctgaataagaagtgttcatctgtaaaa
tacagtaaaatcaaaggcattcccaaactggatgatgccaatgatgctggtggcaaacat
tccctggagtgcacactgatattgacagaaggagactctgccaagtcactagctgtatct
ggattaggtgtgattgggagggacagatatggagtcttcccactcaggggtaaaattctc
aatgtgcgagaagcgtctcataaacagattatggaaaatgcagaaataaacaatattatt
aaaatagttggtttgcaatacaagaaaagttatgatgatgcagaatctctgaaaacctta
cgttatggaaagattatgattatgactgatcaggatcaagatggttctcacatcaaaggc
cttctcatcaattttattcatcacaattggccatcacttttgaagcatggttttcttgaa
gaattcattactcccattgtaaaggcaagcaaaaataagcaggaactttccttttatagt
attcctgaatttgatgaatggaaaaaacatatagaaaaccagaaagcctggaaaataaaa
tactacaaaggattgggtaccagtacagctaaagaagcaaaggaatattttgctgatatg
gaaaggcatcgtattttgtttagatatgctggccctgaagatgatgctgccattaccttg
gcatttagtaagaagaagattgatgacagaaaagaatggttaaccaactttatggaggat
cggagacagcgtaggttacatggcctaccagagcaatttttatatggtacggcaaccaag
catttgacgtacaatgatttcatcaacaaggaattaattctcttctcaaattcagacaat
gagagatctataccgtctcttgtggatggcttcaaaccaggccaacgaaaagttttgttt
acctgtttcaagaggaatgataaacgtgaagtaaaagtcgcccagctggctggatctgtt
gctgaaatgtctgcttatcatcatggcgaacaagcattgatgatgactattgtgaatttg
gctcagaattttgtgggcagtaacaacattaacttgcttcagcccattggtcagtttgga
actcggcttcatggtggcaaagatgctgcaagccctcgttatattttcacaatgttaagc
tctctggcaagactgctttttccagctgtggatgataacttgcttaagttcctttatgat
gataatcagcgtgtagagcccgagtggtatatccccataatccctatggttttgattaat
ggtgctgagggcattgggactggatgggcttgtaaactgcccaactatgatgctagagaa
attgtgaacaatgtcagacggatgctagaaggtttggaccctcatcccatgcttccaaac
tataaaaacttcaaaggcaccatccaggagcttggtcagaaccagtatgctgtcagtggt
gagatatttgttgtggatagaaacacagtagagattacagaacttccagttagaacttgg
acacaggtgtacaaggaacaggtcttagagcccatgcttaatggaacagataaaacacca
gcactaatttctgattacaaagaatatcatactgatacaactgtgaaatttgtggtgaaa
atgacagaagagaaacttgcacaagcagaagctgctggactgcataaagttttcaaactt
caaactactcttacttgcaattccatggtactctttgatcatatgggatgtctgaagaag
tacgaaactgtgcaagacattttgaaagaattctttgatttacgattaagttattatggt
ttacggaaggaatggcttgtaggaatgttgggagcagaatctacaaaacttaataatcaa
gcccgtttcattttagagaagatacaagggaaaattactattgagaataggtcaaagaaa
gatttgattcaaatgttagtccagagaggttatgaatctgacccagtgagagcgtggaaa
gaagcacaagaaaaggcagcagaagaggaagacacgcaaaaccaacatgatgatagttcc
tctgactcaggaactccttcaggccctgattttaattatattttaaatatgtctctatgg
tctcttactaaagaaaaagttgaagaactcattaagcagagagatacaaaagggcgagaa
gttaatgatctcaaaaggaaatctccttcagatctttggaaagaagatttagcagcattt
gttgaagaactggataaagtggaagcacaagaacgagaagatattctggcaggaatgtct
ggaaaagcaataaaaggtaaagttggcaaacctaaggtaaagaaacttcagctggaggag
acaatgccatcaccttatgggagaagaattgttcctgaaattactgctatgaaggcagat
gccagcaggaaactgctgaagaagaagaagggtgatcctgataccacagtagtgaaagta
gaatttgatgaagaatttagtggaacaccagtagaaggtacaggagaagagacattgacc
ccatcagctcctgtaaataaaggtcccaaacccaaaagggagaaaaaggagcctggtacc
agagttagaaaaacacccacatcatctggtaaaccaaacgcaaagaaagtgaagaaacgg
aacccttggtcagatgatgagtccaagtcagagagtgacttggaagaaacagaacctgtg
gttattccaagagattctttgcttaggagagcagcagctgaaagacctaagtacaccttt
gatttctcagaagaggaggaggaggatgctgatgatgacgatgacaataatgatttagaa
gaactgaaagttaaagcatctcccatagcaaatgatggggaagatgaatttgttccttca
gatggcttagataaagatgagtatgcattttctccaggcaaatcaaaagccactccagaa
aaatcgtcatatgacaaaaaaagtcaggattttgggaatctcttttcatttccttcatac
tctcagaagtcagaagatgattcagctaaatttgacagtaatgaagaagatactgcttct
gtttttgcaccatcatttggtctgaagcaaacagataaagttccaagtaaaacagtcgct
gctaaaaagggtaaaccaccttcagatacagcccctaaggccaagagagcacctaaacag
aagaaggtcgtagagactgtaaactctgactcagattctgaatttggcattccaaagaag
actccaacaccaaaaggtaaaggccgaggggcaaagaaaaggaaagcatcaggctcagaa
aatgaaggtgattataaccctgggaggaaaccggctaaaacagccagcaagaaaccgaag
aaaacatcttttgatcaggattcagatgtagacatcttcccctcagacttcacttctgaa
ccacctgctctgccacggactggtcgggctaggaaagaagtcaaatattttgcagagtct
gatgaagaagaagatgttgattttgcaatgtttaattaa
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