Peromyscus leucopus (white-footed mouse): 114697457
Help
Entry
114697457 CDS
T07241
Symbol
Plcg2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00562
Inositol phosphate metabolism
pleu01100
Metabolic pathways
pleu01521
EGFR tyrosine kinase inhibitor resistance
pleu04012
ErbB signaling pathway
pleu04014
Ras signaling pathway
pleu04020
Calcium signaling pathway
pleu04062
Chemokine signaling pathway
pleu04064
NF-kappa B signaling pathway
pleu04066
HIF-1 signaling pathway
pleu04070
Phosphatidylinositol signaling system
pleu04072
Phospholipase D signaling pathway
pleu04360
Axon guidance
pleu04370
VEGF signaling pathway
pleu04380
Osteoclast differentiation
pleu04611
Platelet activation
pleu04613
Neutrophil extracellular trap formation
pleu04625
C-type lectin receptor signaling pathway
pleu04650
Natural killer cell mediated cytotoxicity
pleu04662
B cell receptor signaling pathway
pleu04664
Fc epsilon RI signaling pathway
pleu04666
Fc gamma R-mediated phagocytosis
pleu04670
Leukocyte transendothelial migration
pleu04722
Neurotrophin signaling pathway
pleu04750
Inflammatory mediator regulation of TRP channels
pleu04919
Thyroid hormone signaling pathway
pleu04933
AGE-RAGE signaling pathway in diabetic complications
pleu04935
Growth hormone synthesis, secretion and action
pleu05167
Kaposi sarcoma-associated herpesvirus infection
pleu05169
Epstein-Barr virus infection
pleu05170
Human immunodeficiency virus 1 infection
pleu05171
Coronavirus disease - COVID-19
pleu05200
Pathways in cancer
pleu05205
Proteoglycans in cancer
pleu05206
MicroRNAs in cancer
pleu05214
Glioma
pleu05223
Non-small cell lung cancer
pleu05225
Hepatocellular carcinoma
Module
pleu_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
114697457 (Plcg2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
114697457 (Plcg2)
04014 Ras signaling pathway
114697457 (Plcg2)
04370 VEGF signaling pathway
114697457 (Plcg2)
04064 NF-kappa B signaling pathway
114697457 (Plcg2)
04066 HIF-1 signaling pathway
114697457 (Plcg2)
04020 Calcium signaling pathway
114697457 (Plcg2)
04070 Phosphatidylinositol signaling system
114697457 (Plcg2)
04072 Phospholipase D signaling pathway
114697457 (Plcg2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
114697457 (Plcg2)
04613 Neutrophil extracellular trap formation
114697457 (Plcg2)
04625 C-type lectin receptor signaling pathway
114697457 (Plcg2)
04650 Natural killer cell mediated cytotoxicity
114697457 (Plcg2)
04662 B cell receptor signaling pathway
114697457 (Plcg2)
04664 Fc epsilon RI signaling pathway
114697457 (Plcg2)
04666 Fc gamma R-mediated phagocytosis
114697457 (Plcg2)
04670 Leukocyte transendothelial migration
114697457 (Plcg2)
04062 Chemokine signaling pathway
114697457 (Plcg2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
114697457 (Plcg2)
04919 Thyroid hormone signaling pathway
114697457 (Plcg2)
09156 Nervous system
04722 Neurotrophin signaling pathway
114697457 (Plcg2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
114697457 (Plcg2)
09158 Development and regeneration
04360 Axon guidance
114697457 (Plcg2)
04380 Osteoclast differentiation
114697457 (Plcg2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114697457 (Plcg2)
05206 MicroRNAs in cancer
114697457 (Plcg2)
05205 Proteoglycans in cancer
114697457 (Plcg2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
114697457 (Plcg2)
05214 Glioma
114697457 (Plcg2)
05223 Non-small cell lung cancer
114697457 (Plcg2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
114697457 (Plcg2)
05171 Coronavirus disease - COVID-19
114697457 (Plcg2)
05167 Kaposi sarcoma-associated herpesvirus infection
114697457 (Plcg2)
05169 Epstein-Barr virus infection
114697457 (Plcg2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
114697457 (Plcg2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
114697457 (Plcg2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pleu04131
]
114697457 (Plcg2)
Enzymes [BR:
pleu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
114697457 (Plcg2)
Membrane trafficking [BR:
pleu04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
114697457 (Plcg2)
Endocytosis
Macropinocytosis
Phospholipase C
114697457 (Plcg2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
SH3_9
PH
EF-hand_PLCG1
PH_12
SH2_1
SH3_2
PH_14
GDPD
Motif
Other DBs
NCBI-GeneID:
114697457
NCBI-ProteinID:
XP_037062189
LinkDB
All DBs
Position
5:120034220..120177332
Genome browser
AA seq
1267 aa
AA seq
DB search
MTAMVNVDTLAEYEKSQIKRALELGTVMTVFSARKGTSERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKSTVSRHKGDCCFTIFYGTQFVLSTLSLATDSKED
AMKWLSGLKILHQEVMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKAILPLVNFKVS
SIKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFDQQKSILDEFKRDSSVFILGNTDRPDA
SAVYLQDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETTEPFLFVDEFLTYLFSRE
NSIWDEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIEL
DCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMA
KVFKEVLGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHKTQ
GELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTVEEELVQDTPPTELHFGEKWFHKKVE
RRTSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGVMK
YYLTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDSLSRGEAED
MLMRIPRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVS
YYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALY
DYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQ
IIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFE
WFQSIREITWKIDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSF
VETKADSIVRQKPVELLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTAD
KYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPPESQRKIVMTLTVKVLGARHLPKLGR
SIACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYE
EDMFSDPNFLAHATYPIKGIKSGFRAVPLKNGYSEDIELASLLVFCEMRPVLECEEELYS
SCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLQLYQEKCNRRLREKRV
SNSRFYS
NT seq
3804 nt
NT seq
+upstream
nt +downstream
nt
atgaccgccatggtcaatgtggacacccttgcagaatatgagaagagtcagatcaagaga
gccctggagctagggacggtgatgaccgtgttcagcgcccgcaagggcacctcggaacgg
aggacggtacaggtgatcatggagactcggcaggtggcatggagcaagactgcagacaag
atcgagggcttcctggacatcatggagataaaggaaatccgtccggggaagaactccaag
gacttcgagcgagccaagtccacggtctcccgccacaagggagactgttgcttcaccatc
ttctatggcacccagttcgtcctcagcaccctcagcttggcaactgactcgaaggaggat
gccatgaagtggctctctggcttgaagatcctacaccaggaagtgatgagcgcgtctact
cccaccattatcgagagttggctgagaaagcagatttactcagtagatcaaaccagaaga
aacagcatcagcctccgggagctgaaggccatcttgcccctggtcaacttcaaagtgagc
agcatcaagttcctcaaggacaagctggtggaaatcggtgcacagaaagatgagctcagt
tttgaacagtttcatctcttctataaaaaactcatgtttgaccagcagaaatcgatactt
gacgaattcaaaagggactcctctgtgttcatcctagggaacacagaccggcccgatgcc
tctgctgtctacctgcaggacttccagaggtttctcttacatgagcaacaggagctgtgg
gcccaggatctgaacaaagtccgggagcggatgaccaagttcatcgacgacaccatgagg
gaaaccacggagcccttcttgtttgtggacgagttcctcacgtacctgttttcccgggag
aacagcatctgggatgagaagtacgacgtcgtggacatgcaggacatgaacaaccccttg
tcccattactggatctcctcttcccacaatacgtacctcactggggaccagctgcgaagt
gagtcctccacggaggcgtacatccgctgtctgcgtgctggttgtcgctgcatagagctg
gactgctgggatggacctgacgggaaacctataatctaccatggctggacacggaccacc
aagatcaagtttgatgatgttgttcaggccatccgagaccatgcctttgttacttccagc
ttccccgtgatcctgtccatcgaggagcactgtagtgtggagcagcagcgccacatggcc
aaggtgttcaaggaggtgttgggagacctgctcttgacgaagcccacggaggccagtgct
gaccagctgccctcgcccagccagcttcgggagaagatcattatcaagcataagaagctg
ggcccccgaggtgacgtcgatgtcaatgtggaggacaagaaagatgagcacaagacccag
ggagagctatacatgtgggactccatcgaccagaaatggactcgccactactgtgccatt
gctgacgccaagctgtccttcagtgacgacattgaacagactgtggaggaggagctggtc
caggacactccccccacggagctgcattttggggagaaatggttccataagaaagtggag
aggaggacgagcgcggagaagctgctgcaggaatactgtgctgagacaggggccaaggac
ggcaccttcctggtgcgggagagcgagaccttccccaacgactacaccctctctttctgg
cggtctggtcgggtgcagcactgtcgaatccggtccaccatggagggtggggtcatgaag
tactacctgacggacaacctcacgttcaacagcatctacgccctcatccagcactaccgt
gaggcacacctacgctgtgcagagttcgagctgcggctcaccgacccagtgcccaacccc
aacccacatgagtctaagccgtggtactatgacagcctgagcaggggggaagcggaagac
atgttgatgcggattccccgagacggagccttcctcatccggaagcgggaggggaccgac
tcctatgccatcaccttcagggccaggggcaaggtaaaacactgtcgcatcaaccgggat
ggccggcactttgtgctggggacctctgcctactttgagagcctggtggagcttgtcagc
tactatgagaagcacgcgctctatcgcaagatgaggctacgctatcccgtgacccctgag
cttctggagcgatataatatggaaagagacatcaactctctctatgacgtcagcaggatg
tatgtggacccaagtgaaatcaacccttccatgcctcagaggactgtgaaagcgctctat
gactacaaagccaagcgcagcgatgagttgaccttctgccgcggtgcccttatccacaac
gtctccaaggagcctgggggatggtggaaaggggactatgggactcggatccagcagtac
ttcccgtccaactacgttgaagatatctcagcaggggatgctgaggagatggagaagcag
attattgaagataatccccttgggtctctctgcagaggcatattggaccttaatacctac
aatgttgtgaaggccccccaggggaagaaccagaaagcgttcgtcttcatcctggagccg
aagaagcagggggaccctcctgtggagtttgcgaccgaccgtgtggaggagctgtttgag
tggtttcagagcatccgggagatcacttggaagatagacaccaaggagaacaacatgaag
tactgggagaggaaccagtccatcgccatcgagctctccgacttggttgtctactgcaag
ccgaccagcaaaaccaaggaccatttggaaaaccctgacttccgagaaatccgctccttt
gtggagacaaaggcggacagcattgtccggcagaagcccgttgaactattgcggtacaat
cagaagggcctcacgcgtgtctaccccaagggacagagagttgactcctcaaactatgac
ccattccgcctgtggctgtgcggctcccagatggtggcactcaatttccagactgcagac
aagtacatgcagatgaaccatgcgctgttttcactcaatgggcggacgggctatgtcctg
cagcctgagagcatgcgctctgagaagtatgacccgatgccaccagagtcccagaggaag
atcgtgatgacactcactgtcaaggttcttggtgcacgccacctccccaaactcgggcgg
agtattgcgtgtcccttcgtagaggtggaaatctgcggggctgagtatgacagtaacaag
ttcaagaccacggttgtgaatgacaacggcctcagccctgtctgggctccaacgcaggag
aaggtgacatttgaaatttatgatccaaaccttgcgttcctccgctttgtggtctacgag
gaggacatgttcagtgaccccaacttcctagctcatgccacataccccatcaaagggatc
aagtcagggtttagagcggtccctctgaagaacggatacagtgaagacatcgagctggct
tccctcctggtcttctgtgagatgcggccagtcctggagtgtgaagaggaactctactcc
tcctgtcgccaactgaggaggcggcaggaggagctcaacaaccagctcttcctgtacgac
acacaccagaacctgcgcggagccaaccgcgatgccctggtgaaggagttcaacgttaat
gagaaccagctgcagctgtaccaggagaagtgcaaccggaggttgagagagaagagagtc
agcaacagcaggttctactcctag
DBGET
integrated database retrieval system
