Peromyscus leucopus (white-footed mouse): 114698431
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Entry
114698431 CDS
T07241
Symbol
Gart
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00230
Purine metabolism
pleu00670
One carbon pool by folate
pleu01100
Metabolic pathways
pleu01523
Antifolate resistance
Module
pleu_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
114698431 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
114698431 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
114698431 (Gart)
Enzymes [BR:
pleu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
114698431 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
114698431 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
114698431 (Gart)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
AIRS_C
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_2
ATP-grasp_3
ATP-grasp_4
Dala_Dala_lig_C
RimK
ATP-grasp_5
LUD_dom
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
114698431
NCBI-ProteinID:
XP_028732935
LinkDB
All DBs
Position
12:7037734..7063624
Genome browser
AA seq
1010 aa
AA seq
DB search
MAARVLVIGSGGREHALAWKLAQSHHVKQVLVAPGNAGTACSGKIVNAAVSIDDHTVLAQ
FCKDEKIEFVVVGPEAPLAAGIVGDLTRAGVRCFGPTAQAAQLESSKKFAKEFMDRHGIP
TAQWRAFTTPEDACSFIMSANFPALVVKASGLAAGKGVIVAKSKEEACRAVQEIMQEKSF
GAAGETVVVEECLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLDGDQGPNTGGMGAYCPAP
QVPKDLLLKIKNTILQRTVDGMQQEGVPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLNTSLPVWLENHTAITVVMASKGYPGAYTKGVEITGFPEA
QALGLQVFHAGTALKDGRVVTSGGRVLTVTAVQENLVSALEEARKGLAAIKFEGAVYRKD
IGFRAVAFLQQPRGLTYKESGVDIAAGNMLVKKIQPLAKATSRPGCSVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCSKHDTIGQDLVAMCVNDILAQGAESLFFLDYFAC
GKLDLKTTEAVVAGIAEACGQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
QLERIAEGDVVVGVASSGLHSNGFSLVRKIVERSSLQYSSPAPDGCGDQTLGDLLLTPTR
IYSRSLLPVIRSGHVKALAHITGGGLLENIPRVLPQKLGVDLDACTWKIPKVFSWLQQEG
QLSEEEMARTFNCGVGAALVVSKDQADQILHDIRQRQEEAWVIGSVVACPEDSPRVRIKN
LIETMQINGSKMTNGFQRSNFPAHHKKARVAVLISGTGSNLQALIDSTRDPKSATHIVVV
ISNKAGVAGLDKAQKAGVPTRVINHKLYKSRIEFDNAVDHVLEEFSVDIVCLAGFMRILS
GPFVKKWDGKMLNIHPSLLPSFKGSNAHEQVLEAGVMITGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVATLSERVKVAEHKIFPAALQLVASGAVRLGDDGKIHWTREQ
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagttctcgtgattggcagtggagggagggagcatgccctggcctggaaa
cttgcacagtctcatcatgtcaaacaagtgttggttgccccaggaaatgcaggcactgcc
tgttctggaaagatcgtaaatgctgctgtctccattgatgatcacactgtccttgctcag
ttctgcaaagatgaaaagattgaattcgtggttgttgggccagaggcccctctggctgca
gggattgttggggacctgacccgagcaggagtacgatgctttggccccacagcccaagca
gctcagttagagtccagtaaaaagtttgccaaagagtttatggaccgacatggaatcccg
actgcacagtggagagcattcaccacacctgaagatgcctgcagcttcattatgagcgcc
aactttcctgctttggttgtgaaggccagtggccttgctgctgggaaaggggtgattgtt
gcaaagagcaaagaggaggcctgcagagccgtgcaggagatcatgcaagaaaagtctttt
ggagcagctggagaaacggttgtcgtggaagagtgtctggacggggaagaagtgtcttgt
ctgtgtttcactgatgggaagacagtggccccaatgcccccagcacaggaccacaaacga
ttgctggatggagaccagggccccaacacaggggggatgggagcctattgcccagcacct
caggttcctaaagatttgttactgaaaattaaaaacactattcttcagagaaccgtagat
ggcatgcagcaggaaggtgttccttacacaggaattctctatgctggtatcatgctgacc
aaagatggcccaaaagttttggagtttaattgccgttttggtgatccagaatgccaagta
atcctcccgcttcttaaaagtgacctttatgaagtgattcagtccaccttagatggcctg
ctgaatacatctctgcctgtttggctagaaaaccatactgccataactgttgtcatggcc
agtaaagggtatcctggagcctataccaagggtgtggagatcacagggtttcctgaggcc
caggctttaggactccaggtattccacgcgggcactgctcttaaagatggcagagtagtg
accagcggaggcagagtcctcacggtaacagccgtccaggaaaatctggtgtcagccctt
gaagaagccaggaaaggactcgccgctataaagtttgagggagcagtttataggaaggac
attggcttccgtgctgtggccttcctccagcagcccaggggcctgacttacaaggaatct
ggggtagacattgcagccggaaatatgctggttaagaaaattcagcctttagcaaaagcc
acctccagaccaggctgcagcgttgaccttggaggctttgccggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcctctggaacagatggtgttgggactaaactg
aagattgcccaactgtgcagtaagcacgacaccattggtcaggatttggtcgccatgtgt
gtcaacgacatcctagcccaaggagcagagtccctcttcttcttagactactttgcctgt
ggaaagcttgacctcaaaacgactgaagctgtagttgctggaattgctgaagcttgtgga
caagctggctgtgctctcctgggtggggagaccgcggagatgcccgacatgtacccccct
ggcgaatatgacctcgccgggtttgctgtgggcgctatggagagggaccagaaactccct
cagctggaaaggatcgccgaaggggatgttgttgttggagtagcttcctctgggcttcac
agcaacggctttagccttgtgaggaagattgtggagaggtcttctctccagtactcctct
ccagcgcctgatggctgtggtgatcagactctaggggacctgcttctaaccccaaccagg
atctacagccgttcgctgctgcctgtcatccgttctggccatgtcaaagccttggctcac
attactggaggggggttgctggagaacatcccccgagtcctgcctcagaagcttggagta
gatttagatgcttgcacctggaagatccccaaggtcttctcgtggttacagcaggaagga
cagctctctgaagaggaaatggccagaaccttcaactgtggggttggagctgccctggtg
gtgtctaaggaccaggcagaccagattctgcacgacattcggcagcgccaggaggaagcc
tgggtgataggcagtgtcgtggcatgtcctgaagattcccctcgtgtcagaatcaagaat
ctgatcgaaaccatgcaaataaatgggtcaaagatgacaaatggcttccagagaagtaat
ttccctgcccaccacaagaaggcaagagtggctgtcttaatatctggaacaggatcgaac
ctccaagcactcatagacagcacccgggatccaaagagcgccacacacattgtcgttgtc
atctccaacaaggctggggtcgcgggcttagacaaagcccagaaggctggcgttcccacc
agagtaattaaccataaactatataaaagtcggattgaatttgacaatgctgttgaccac
gtcctggaagagttctctgtagacatagtctgtctcgcgggattcatgaggattctctct
ggcccttttgtcaaaaaatgggatgggaaaatgctcaacatccacccatccttgctgcct
tctttcaagggttcaaacgctcacgagcaagtcctggaagctggagtcatgattaccggg
tgtaccgtacactttgtagctgaagatgtagatgcgggacagatcatcctacaagaagcc
gtccctgtgaagaggggcgacaccgttgcgaccttgtctgaaagagttaaagtggcagaa
cataagatcttccctgcagccctccagctggtggccagcggggctgtgcgtctgggggac
gatggcaagatccactggaccagagagcagtga
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