Peromyscus leucopus (white-footed mouse): 114701128
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Entry
114701128 CDS
T07241
Symbol
Sirt1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00760
Nicotinate and nicotinamide metabolism
pleu01100
Metabolic pathways
pleu04068
FoxO signaling pathway
pleu04148
Efferocytosis
pleu04152
AMPK signaling pathway
pleu04211
Longevity regulating pathway
pleu04213
Longevity regulating pathway - multiple species
pleu04218
Cellular senescence
pleu04310
Wnt signaling pathway
pleu04922
Glucagon signaling pathway
pleu04936
Alcoholic liver disease
pleu05031
Amphetamine addiction
pleu05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
114701128 (Sirt1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
114701128 (Sirt1)
04068 FoxO signaling pathway
114701128 (Sirt1)
04152 AMPK signaling pathway
114701128 (Sirt1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
114701128 (Sirt1)
09143 Cell growth and death
04218 Cellular senescence
114701128 (Sirt1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
114701128 (Sirt1)
09149 Aging
04211 Longevity regulating pathway
114701128 (Sirt1)
04213 Longevity regulating pathway - multiple species
114701128 (Sirt1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
114701128 (Sirt1)
09165 Substance dependence
05031 Amphetamine addiction
114701128 (Sirt1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
114701128 (Sirt1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pleu03036
]
114701128 (Sirt1)
03029 Mitochondrial biogenesis [BR:
pleu03029
]
114701128 (Sirt1)
Enzymes [BR:
pleu01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
114701128 (Sirt1)
Chromosome and associated proteins [BR:
pleu03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
114701128 (Sirt1)
Mitochondrial biogenesis [BR:
pleu03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
114701128 (Sirt1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
114701128
NCBI-ProteinID:
XP_028736920
LinkDB
All DBs
Position
16_21:31944634..31966621
Genome browser
AA seq
760 aa
AA seq
DB search
MADEAALALQAGGSPSAAAAAAAAAAAIAMEAAAAQPAEEPLRKRPRRDGPGLGHSPGEP
SSAAVAAAAGCETPSAAAPAALWREAVGAAAAVVTAAAGAEREAPATAAAGDGDNGSGLR
REPRAADDFDDDEGEEEEDDEAAAAAAAAAAAAIGYRDNLLFTDEIITNGFHSCESDEED
RTSHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVIN
ILSEPPKRKKRKDINTIEDAVRLLQECKKIVVLTGAGVSVSCGIPDFRSRDGIYARLAVD
FPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQN
IDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAI
MKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINR
EPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELVHLSE
LPPTPLHISEDSSSPERTVPQDSSVISTLVDQATKNKVDDLEVSESKGGVEEKSQVVQTC
RNVEGINVENPDFKAVGSSTGEKNERPSVVEAVRKCWPNRLAKEQISKRLDGNQYLFVPP
NRYIFHGAEVYSDSEDDVLSSSSCGTNSDSGTCPSPSLGEPMEDESEIEEFYNGLEDDND
RPEGAGGSGFGADGGDQEGVNEATAMRQEVTGVNCPSDKL
NT seq
2283 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggcgctcgcccttcaggccggcggctccccttccgcggcggcggcg
gcggcggcagcggcggccgccatcgccatggaggccgcggcggcgcagcccgccgaggag
ccgctccgtaagaggccgcgccgagacgggcccggcctcgggcacagccccggcgagccg
agctccgcggcggtagccgccgccgcggggtgtgagacgccgagcgccgcggccccggcg
gcgctgtggcgggaggcggtcggggcggcggcggcggtggtgacggcggcggcgggcgcg
gagcgggaggccccggcgaccgccgcggccggggacggagacaatgggtcgggcctgcgg
cgggagccgagggctgccgacgacttcgacgacgacgagggcgaggaggaggaggacgac
gaggcggcggcggcggcggcggcagcggcagcggcagcgatcggctaccgggacaacctc
ctgttcactgatgagatcatcactaatggctttcactcctgtgaaagtgacgaagaggac
aggacttcccacgcaagctctagcgactggactccacggcccaggataggtccatatact
ttcgttcagcagcatctcatgattggcaccgatcctcgaacaatccttaaagatttacta
ccagaaacgattcctccacctgagctggatgacatgacactgtggcagattgttattaat
atcctttcagaaccaccaaaacggaaaaaaaggaaagacattaatacaattgaagatgct
gtgagattactacaagagtgcaagaagatagtcgtgttaactggagccggggtttctgtt
tcctgtgggatacctgacttcagatcacgagatggtatttatgctcgccttgctgtggac
ttcccagatctcccagatcctcaagccatgtttgatattgagtattttagaaaagatcca
agaccattcttcaagtttgccaaggaaatatatcccggacagttccagccatctctgtgt
cacaaattcatagctttgtcagataaggaaggaaaactacttcgaaactatactcaaaat
atagataccttggagcaggttgcaggaatccaaaggatcatccagtgtcatggttccttt
gcaacagcatcttgcctgatttgcaaatacaaagttgattgtgaagctgttcgaggagac
atttttaatcaggtagttcctcgttgtcctaggtgcccggctgatgagccacttgctatc
atgaagccggagattgtcttctttggtgaaaatttaccagaacaatttcatagagccatg
aagtatgacaaagatgaagttgacctcctcattgttattgggtcttctctgaaagtaaga
ccagtagcactaattccaagttccataccccatgaagtgcctcaaatattaataaatagg
gaaccattgcctcatctgcattttgatgtagagcttcttggagactgtgatgtcataatt
aatgagttgtgtcataggttaggtggtgaatatgccaaactttgttgtaaccctgtaaag
ctttcagaaattactgaaaaacctccacgaacacaaaaggaattggttcatttatcagaa
ttgccaccaacacctcttcatatttcagaagactcaagttcacctgaaagaactgtaccc
caagactcttctgtgatttctacacttgtagaccaagcaacaaagaacaaagttgatgat
ttagaagtatctgaatcaaaaggtggtgtggaagaaaaatcacaagtagtacagacttgt
aggaatgtggagggcattaatgtggaaaatccagatttcaaggctgttggttccagtact
ggagagaaaaacgaaagaccttcagttgtggaagcagtgagaaaatgttggcccaacaga
cttgcaaaggagcaaattagtaagcgtcttgatggtaatcagtacctttttgtaccacca
aatcgttacatattccatggtgcggaggtgtactcagactctgaagacgatgtcttatcc
tctagttcctgtggcactaacagtgacagtggcacatgcccgagtccaagtttaggagaa
cccatggaagatgaaagtgagattgaagagttctataatggcttggaagatgataatgat
agacctgaaggtgctggaggatctggatttggagctgatggaggggatcaagagggagtt
aatgaagctacagccatgagacaggaggtgacaggtgtaaactgtccatcagacaaatta
taa
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