Peromyscus leucopus (white-footed mouse): 114701373
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Entry
114701373 CDS
T07241
Symbol
Pde5a
Name
(RefSeq) cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1
KO
K13762
cGMP-specific 3',5'-cyclic phosphodiesterase [EC:
3.1.4.35
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00230
Purine metabolism
pleu01100
Metabolic pathways
pleu04022
cGMP-PKG signaling pathway
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
114701373 (Pde5a)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
114701373 (Pde5a)
Enzymes [BR:
pleu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
114701373 (Pde5a)
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Motif
Pfam:
PDEase_I
GAF
GAF_2
HD-CE
DUF6970
Motif
Other DBs
NCBI-GeneID:
114701373
NCBI-ProteinID:
XP_028737287
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Position
6:95359781..95552680
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AA seq
865 aa
AA seq
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MERAGPSSARPKQQRDQDWVEAWLDDHRDFTFSYFVRKATREMVNAWFSERVHTIPVCKE
GIRAHSESCSCPSQPSPHAETTTPAAPARKISASEFDRPLRPIVVKDSEGTVSFLSDSGT
KEQMPLTPPRFDSDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLV
CEDSSKDKFLVSRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAAFGEPLNIKDAYEDPR
FNAEVDQITGYRTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFC
GIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILQKIAATIISFMQVQKCTIF
IVDEDCSDSFSSVFHMECEELGKSADTLTREHDANKINYMYAQYVKNTMEPLNIPDVAKD
KRFPWTNENTGSVNTQHTGSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKIKPFNQNDEQ
FLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQALAAAVVPS
AQTLRITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNV
AYHNWRHAFNTAQCMFAALKSGKIQNKLTDLETLALLIAALSHDLDHRGVNNSYIQRSEH
PLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIK
RRGEFFELIRKNQFSFEDPLQKELFLAMLMTACDLSAITKPWPIQQRIAELVAAEFFDQG
DRERKELNIEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCLPLLDGCRKNR
QKWQALAEQQEKTLINGESSQAKRD
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
atggaacgagccggccccagctccgcgcggccgaagcagcagcgggaccaggactgggtg
gaagcgtggctggatgatcaccgggactttaccttctcttactttgttaggaaagccacc
agagaaatggtcaacgcatggttttcagagagagttcacaccatcccagtatgcaaggaa
ggcatccgagcccacagcgagtcttgctcctgcccttcgcagccaagtcctcatgcagag
accaccacccctgcagccccagccaggaaaatctctgcctcagaatttgacaggcctctt
agacccattgttgtcaaggattccgagggaactgtcagctttctctccgactcaggaaca
aaggaacagatgccactaacccccccaagatttgatagtgatgaaggggaccagtgctcc
agactcttggaattagtaaaagatatttccagtcacttggatgtcacagccttatgtcac
aaaattttcttgcatatccatggactcatctccgccgaccgctattccctattccttgtc
tgtgaggacagctccaaagacaaatttctggtcagccgcctctttgatgtcgctgaaggt
tcgaccctggaggaagcttccaataactgtatccgcctggagtggaacaaaggcattgtg
ggacatgtggcagcttttggcgagcccttgaatatcaaagatgcctatgaggatcctcgg
ttcaatgcagaagttgaccaaattacagggtacaggacacaaagtattctttgtatgcca
attaagaaccacagagaagaggttgttggtgtggcccaggccatcaacaagaagtcagga
aatggtgggacgttcaccgaaaaagatgaaaaggactttgctgcctatttggcattttgt
ggtattgtccttcacaacgctcagctctatgaaacgtcactgctggagaacaaaagaaat
caggtgttgctcgaccttgctagcttaattttcgaagagcagcagtcattggaagtaatt
ctgcagaaaatagctgccaccattatctccttcatgcaggtgcagaagtgcaccatattc
atcgtggatgaggactgctctgattccttctctagtgtgttccacatggagtgtgaggaa
ctaggaaaatcagctgacactttaacaagggagcatgatgcaaacaaaatcaattacatg
tatgctcagtatgtcaaaaacacgatggagccacttaatatccctgatgtcgctaaggac
aaaagatttccctggacaaatgaaaacacgggcagtgtaaacacgcagcacactggaagt
ttgctttgcacacctataaaaaatgggaagaagaacaaagtcataggggtttgccaactt
gtcaataagatggaggagaataccggcaagattaaacctttcaaccaaaacgatgaacag
tttctggaagcttttgttatcttctgtggcttggggatccagaacacccagatgtatgaa
gcggtggagagagccatggccaagcaaatggtgacattggaggtcctgtcctatcacgcc
tcagcagccgaggaagaaacgagagagctccaggctttagcggctgctgtggtaccatct
gcccaaacccttagaattacggacttcagcttcagtgactttgagctatctgacctggaa
acagcactgtgtaccattcggatgttcaccgacctcaaccttgtgcagaacttccagatg
aaacatgaggttctttgcagatggattttaagtgtcaagaagaattatcggaagaacgtt
gcctatcacaattggaggcatgcttttaacacggcacagtgcatgtttgctgccctgaaa
tcaggcaagattcagaacaagttgacggatctagagacacttgcgttgctgattgctgct
ttaagtcatgatttggatcatcgcggtgtgaacaactcatacatacagcggagtgaacat
ccgctggcccagctgtattgccactccatcatggaacaccatcatttcgatcagtgtttg
atgattctaaatagcccaggcaaccagattctcagtggcctctccattgaagaatataag
accaccctgaaaataatcaagcaagccattttagctacagacctagcactgtacattaag
agacgaggagaattttttgaacttataagaaaaaatcaattcagctttgaagatcctctt
caaaaggagttatttctagcaatgctgatgactgcctgtgatctttctgcgattacgaag
ccctggcctattcaacaacggatagcagaacttgtggcagctgagttcttcgatcaaggg
gacagagagagaaaagaactcaacatcgagcctgctgatctaatgaacagggagaagaaa
aataaaatcccaagtatgcaagttgggttcatagatgccatctgcttgcagctgtatgag
gccctgacgcacgtttcggaggactgtttgcccttgctggatggctgcaggaagaacaga
cagaaatggcaggccctggcagagcagcaggagaagacgctcattaacggagagagcagc
caggccaagcgagactga
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