KEGG   Peromyscus leucopus (white-footed mouse): 114702344
Entry
114702344         CDS       T07241                                 
Symbol
Tgfbr1
Name
(RefSeq) TGF-beta receptor type-1 isoform X1
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
pleu  Peromyscus leucopus (white-footed mouse)
Pathway
pleu04010  MAPK signaling pathway
pleu04060  Cytokine-cytokine receptor interaction
pleu04068  FoxO signaling pathway
pleu04144  Endocytosis
pleu04218  Cellular senescence
pleu04350  TGF-beta signaling pathway
pleu04371  Apelin signaling pathway
pleu04380  Osteoclast differentiation
pleu04390  Hippo signaling pathway
pleu04520  Adherens junction
pleu04659  Th17 cell differentiation
pleu04926  Relaxin signaling pathway
pleu04933  AGE-RAGE signaling pathway in diabetic complications
pleu05142  Chagas disease
pleu05161  Hepatitis B
pleu05166  Human T-cell leukemia virus 1 infection
pleu05200  Pathways in cancer
pleu05210  Colorectal cancer
pleu05212  Pancreatic cancer
pleu05220  Chronic myeloid leukemia
pleu05225  Hepatocellular carcinoma
pleu05226  Gastric cancer
pleu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pleu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114702344 (Tgfbr1)
   04350 TGF-beta signaling pathway
    114702344 (Tgfbr1)
   04390 Hippo signaling pathway
    114702344 (Tgfbr1)
   04371 Apelin signaling pathway
    114702344 (Tgfbr1)
   04068 FoxO signaling pathway
    114702344 (Tgfbr1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    114702344 (Tgfbr1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    114702344 (Tgfbr1)
  09143 Cell growth and death
   04218 Cellular senescence
    114702344 (Tgfbr1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    114702344 (Tgfbr1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    114702344 (Tgfbr1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    114702344 (Tgfbr1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    114702344 (Tgfbr1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114702344 (Tgfbr1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    114702344 (Tgfbr1)
   05212 Pancreatic cancer
    114702344 (Tgfbr1)
   05225 Hepatocellular carcinoma
    114702344 (Tgfbr1)
   05226 Gastric cancer
    114702344 (Tgfbr1)
   05220 Chronic myeloid leukemia
    114702344 (Tgfbr1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    114702344 (Tgfbr1)
   05161 Hepatitis B
    114702344 (Tgfbr1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    114702344 (Tgfbr1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    114702344 (Tgfbr1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    114702344 (Tgfbr1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pleu01001]
    114702344 (Tgfbr1)
Enzymes [BR:pleu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     114702344 (Tgfbr1)
Protein kinases [BR:pleu01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   114702344 (Tgfbr1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH FTA2 Haspin_kinase Psg1
Other DBs
NCBI-GeneID: 114702344
NCBI-ProteinID: XP_028738606
LinkDB
Position
2:58433565..58495713
AA seq 507 aa
MEAAAAAAPRRRLLLFVLVAAAAAATLLPGTEALQCFCHLCTKDNFTCETDGLCFVSVTE
TTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGAVTTTYCCNQDHCNKIELPTTGPFSEK
QSPGLGPVELAAVIAGPVCFVCIALMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTT
LKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSS
REERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYT
VTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAV
RHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCS
IGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWY
ANGAARLTALRIKKTLSQLSQQEGIKM
NT seq 1524 nt   +upstreamnt  +downstreamnt
atggaggcggcggcggctgctgctccgcgtcgccggctgcttctcttcgtgttggtggcg
gcggcggcggcggcgacgctgctaccggggacggaggcattacagtgtttctgccacctc
tgtacaaaagataattttacctgtgagacggatggtctttgttttgtctcagtcacagag
accacagataaagttatacacaacagtatgtgtatagctgaaatcgacctaattcctcga
gacaggccatttgtttgtgcgccatcttccaaaactggggctgttacgacaacatattgc
tgcaatcaggaccactgtaataaaatagaactcccaactacaggacctttttcagaaaag
cagtcccctggcctcggtcctgtggagctggccgctgtcattgctggtccagtctgcttc
gtctgcattgcacttatgctgatggtctatatctgccacaaccgcactgtcatccaccat
cgtgtgccaaatgaagaagatccatccctagatcgccccttcatttcagagggcaccacc
ctaaaagatttaatttatgatatgacaacatcaggatctggatcaggtttaccattgctt
gttcagagaacaattgccaggaccatcgtgttacaagaaagcattggcaaaggtcggttt
ggagaagtttggcgaggcaagtggcggggagaagaagttgctgtgaagatattctcttct
agggaagaacgttcgtggttccgcgaggcagagatttatcagactgtgatgttacgccat
gaaaacatcctaggatttatagcagcagacaacaaagacaatggcacctggactcagctg
tggctggtgtcggattaccacgagcatggatccctttttgattacttgaatagatacact
gttacagtagaagggatgatcaaactggctctgtccaccgcaagcggtcttgcccatctt
cacatggagattgttggtacccaaggaaagccagctattgctcacagagatttgaaatca
aagaatatcttggtgaagaagaatggaacctgctgtattgcagacttgggactggcagtg
agacacgattctgccacagatacaattgatattgctccaaaccacagagtaggcactaaa
aggtacatggcccctgaagttctagatgactctataaatatgaaacattttgaatccttc
aaacgtgctgacatctatgcaatgggcttagtgttctgggaaattgctcgacgctgttcc
attggtggaattcatgaagactaccagctgccttattatgatcttgtaccttctgatcca
tcagttgaagaaatgagaaaagtagtttgtgaacagaagttaaggccaaatattccaaac
agatggcagagctgtgaagccttgagagtaatggctaaaattatgagagaatgttggtat
gccaatggagcagctaggctgacagctttgcggattaaaaaaacattgtcacagctcagc
caacaggaaggcatcaaaatgtaa

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