Peromyscus leucopus (white-footed mouse): 114702768
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Entry
114702768 CDS
T07241
Symbol
Setx
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
114702768 (Setx)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
pleu03021
]
114702768 (Setx)
Enzymes [BR:
pleu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
114702768 (Setx)
5.6.2.5 RNA 5'-3' helicase
114702768 (Setx)
Transcription machinery [BR:
pleu03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
114702768 (Setx)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
nSTAND3
ResIII
Helicase_RecD
AAA_16
Motif
Other DBs
NCBI-GeneID:
114702768
NCBI-ProteinID:
XP_028739148
LinkDB
All DBs
Position
4:complement(10295324..10349947)
Genome browser
AA seq
2698 aa
AA seq
DB search
MSTCCWCTPGGPSTVDVLKCYASSTGSSEFQTADEDLCYCLECVAEYHRARDEVPFLHEV
LWELETLRLINHFEKSMKAEVEDDDELYIVDNNGEEQLFDCSGQDFENKLRVPLFEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKYPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPAHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEKQSDDDSMDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNVSYNREIQNIRNSSIRTKLEPEPHFDDMVTCSQIVYNYN
PKKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLYSEVKDVLNQTDAVCDKVTEFFILILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSDKPPGSTPKGAPIISSLALHSVPSNSVQLACVQLIR
GLLKEGYQLGQQTLCKQFWDKLNLFLRGNLSLGWQLTAQETHELQMCLKQIIRNIKFKLP
QYSTFGDPTSTCKTPPSFKEESEQIDRKPKKDIYCLENYSPTSSKEPVKADRNQVLIKAN
NREEEGIKQHYIDLNEEEPLPAELWLKQESEATVSGSDQEQVKISTEKSVKETSSHTPQN
NTLRNGPEWGCDRGVIALTRSLTDSSTDSLDKVSTSNEDVSLKDDTVGKNSKPKSKAQKD
EICAKLSHVIKKQHRKSTLINNTIKLEENPAMPDLENSCSGRERGVLKEDAVTHDVSLDP
VLDDEHGEQNFQNSSLLKKKQFKSEEFYNSDENKCQIQEQHATDDLLLCTEVTDTSVKKT
SCESPVKVVVESRDKEMRKSIVQTSNLVQGQVSHSSSKPLVTGSQIDLCNITSIAQTTVI
QFPSGSSKSPSQLQRKDDDRRCLTANRNSADSCHGQIIVISDSDEEDDEKSHGIEKHIKQ
GEVCMEKDCPEQHGSVVNTGVEKQLIKEEETKYPVEFEDSESQVFEFESSSEVFSVWQDH
SVDSKNSLHKDGNSCVTHVADSTNSSLGWGPDSVSGEVVTNEAEDVEEHAEPHSVSAEEF
CKTEGKKHKRKRCDRVSAEDPQRPSSSVTFERLADDRDLAGSDLKSTDMGISAPSSSVER
DPTVSLMKSTKPRTNSKPARKVPASKVIKKTHLDTKRVQNKSSCYISCRTSPAIVPPKKL
RQCPEPTSTVEKLGLKKAPRKAFELSQRSLECIVQLRDHGKTVGVVDAPKKTKLISPQTL
SIKNNKKLLTSQDLQFQRLMRSRSHQKRDLDYTARTVSRVTVQGSDVLVPDSDGPANHRG
NELPANSNEKQLAKCMPSKSEVAKAISDPQVTDIAYLVNQCESRVLSGGVPTDVMLSTPE
EPVGEGAPTVQGGEVAAVKAAEPESSSDTDDDNLFLTQHDPQDMDLCSQMEDDDKPIVVA
HKDTVQREESVSQPHLESLSVTKCKYKDCVETTRNQSEYCPRHAEAKTTDDDVFRKPGLP
IRSSLRPTTTKIFSSSSASRTANLSKSLESTILQSVLKNKSSGAQPNLKVTPPTSLESQK
PVAEVKSLSSIFHFQTPSSSTKQSHKLTLSENKPRSASSPVNIVLPSQSIFDTFIKEVLR
WKYQMFLNFDKCGAPTSLCQSISRPVPVRFQDCAEYFNVFLPLIILNAFETVAQEWFNSP
NKENFYYLHLRKFPADYKKYWEFMIYLEESELAKQLHPKENDLVFLVPTRLNREKKDMDR
NGMQDRNGYYCGYVHKFRRTSVMRSGKAECSLCIQTQDNLPASLNELTKCIVISSLVTTQ
RKLKAMSLLNSRNQLARAVLNPNPMDFCTKDLLTTTSERIIAYLKDFNEDQKKAIETAYA
MVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKGRSDENFNAKIKQNRVLVCA
PSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINTEVLKFSLDSQVNH
RMKKDLPSHIQEMHRRKEFLDGQLDELSRQRALCRGGREMQRQELDGYIAQVSKERQELA
SKIKEVQGRPQKTQNTIILESHVICCTLSTSGGFLLESAFRGQGGVPFSCVIVDEAGQSC
EVETLSPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCKLLEENVEQNMIG
RLPVLQLTIQYRMHPDICLFPSNYVYNKNLKTNRFTEAVRCSSEWPFQPYLVFDVGDGSE
RRDNDSYINVQEIKLVMEIIKLIKDKRKDISFRNIGIITHYKAQKTMIQKDLEKEFDKKG
LLQPIMMGESRQQDPEASSQKKKSSECMHASDEPDFSTFTQSGISCVENGVTHTGPAEVD
TVDAFQGRQKDCIIVTCVRASAVQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQ
HWNELIQDAQKRGAIIKTSDPNYRHDAMKILKLKPVLQRSLTHPPATAPEAPRPQGGLPS
NKLDSGLARTSFAASLYHTPSDAVPSKEPERLSLQDRLRDPRLHRRSDTEAKGTFLKDAQ
PASPQLPGVVHLLGEPGFPGLFPDLSFVVPPSTAIVAPLSSHRSPLQAEPPPAHPAAPST
SRRKYSDPGSGFSHRREPGAFGEEERRVSVTHHMLRSTNWDKRGLEQEDSSAKKRRFL
NT seq
8097 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgctgttggtgtaccccaggtggtccttccaccgttgatgtcctaaagtgc
tatgcatctagcactggctcaagtgaatttcaaacagctgatgaagacctctgctactgc
ttagagtgcgtggctgagtaccacagagccagagatgaggtgccattcttgcatgaggtt
ttatgggaattagaaaccttacgcctcataaatcactttgagaagtctatgaaagcagaa
gttgaagatgatgatgaattatatatagtagacaacaatggagaggaacagctatttgac
tgtagtggccaagattttgaaaataaactccgagttcctctttttgaaatactgaagtac
ccttacttgcttctgcatgagcgtgttaatgaactgtgtgtggaagcactttgtcgaatg
gaacaagccaattgctcctttcaggtttttgacaaatacccaggcatctatttgtttctg
gttcatcccaatgaaatggttcggcgatgggctattctgactgcaagaaacctggggaaa
gtggacagagatgactattacgacttacaggaagttttaacttgcctttttaaagtcatt
gagttaggacttttggaaagtccagacatttacacatcttctgtgcttgaaaaaggcaaa
ctgatccttctgcctgcacacatgtatgatactacgaactataaaaactactggctaggt
atttgcatgttgctgactattcttgaggagcaagccatggattcactgttgctgggctca
gacaaacaaaatgattttatgcaatcaatccttcacaccatggagaagcagtcggatgat
gacagcatggatcctttctggccagcattacactgtttcatggtgattctggatcgcctt
ggatctaaagtgtggggtcaacttattgaccctattgaagcatttcaaaccatcattaac
aatgtgagctacaatagagagatccaaaatataaggaacagctccataaggaccaagtta
gaaccggagccacattttgatgatatggtgacatgcagccagattgtctataactataat
cctaaaaagaccaaaaaggattcagggtggagatcagccatttgtccagattattgtcct
aacatgtatgaagaaatggaaacattagccaatgtacttcagtcagatattggtcaagat
atgcgcgttcataacagtacctttctgtggttcataccttttgttcagtcactcatggat
cttaaggacttgggtgtagcttacattgtagaagttattcatcatctatactctgaagtc
aaagatgtcctcaaccagacagatgctgtgtgtgacaaagtcactgaattttttattctg
attttagtgtctgtgattgaactgcatagaaataagaaatgtttgcatctgctgtgggtg
agttcccagcagtgggtagaagctgttgtgaagtgtgccaagcttcctaccactgcattt
gcacggagttctgacaagccacctggaagtacccccaagggagcaccaataatatcatca
ttggcattgcattcagtgccctctaactctgtccagcttgcttgtgtccaattgattagg
ggtcttctcaaagaaggttatcagcttggtcagcaaacactttgtaagcagttctgggat
aaacttaacttattccttcgaggaaatttatctctgggttggcagttgactgctcaagaa
acccatgagttacaaatgtgtttgaaacaaataattagaaacataaaattcaaattgccc
caatatagcacttttggggatccaacttctacatgtaaaactcctccatcttttaaagaa
gaaagtgaacagatagacaggaagcctaaaaaagacatttattgcctggaaaattacagc
ccaacatcttctaaagaaccagtgaaagctgaccgtaatcaagtattgattaaagcaaat
aatagagaagaggagggcatcaagcagcattatattgatttgaatgaagaagagcctctt
ccagctgaattgtggttgaagcaggagagtgaggccactgtttctggaagtgatcaagag
caagttaaaataagcacagagaagtctgtaaaagaaacctcttcacatacaccacagaat
aatactttaagaaatggcccagaatggggatgtgacagaggagtcatagcattaacacgt
tcattgactgattctagcactgattctctggacaaggtatctacatcaaatgaagatgtc
tcattaaaggatgacactgttggtaaaaactcaaaaccaaagtctaaagcacagaaagat
gaaatttgtgcgaagttatcacatgtcataaagaagcaacacaggaaaagtactttgatc
aataacactatcaagctagaggaaaatccagctatgcctgaccttgagaactcctgttca
ggaagagagagaggagttctaaaggaagatgctgtcacacatgatgtgtctttagaccct
gttctggatgatgaacatggtgagcaaaattttcaaaacagttcgttgttaaaaaagaaa
cagtttaaaagtgaggagttctataattctgatgaaaacaagtgtcaaatccaggaacag
catgctactgatgatttgttattatgtacagaagttactgatacatcggtgaagaaaact
tcatgtgagagtcctgtaaaggtggtagttgaatcaagagataaggaaatgagaaagagt
atagtgcagacttctaacttggtacaaggacaggtgtctcacagcagtagcaagcctttg
gtcacaggttctcaaatagacctctgtaacatcacttcaatagctcaaaccactgttatt
cagttcccatcagggtcaagtaaaagtccatcccagctacaaagaaaagatgatgataga
agatgtttgacagctaaccgaaacagtgctgactcttgccatgggcagattattgttatt
tcagattctgatgaagaagatgatgaaaaaagtcatggtattgagaaacacatcaaacag
ggcgaagtatgcatggagaaagactgtccagagcagcatggttcagtagttaatactggt
gtggaaaagcagcttataaaggaagaagaaacaaagtacccggtagaatttgaggactct
gaatctcaggtttttgagtttgaaagttcatctgaagtgttttcagtttggcaggatcat
agtgtagacagcaagaactcccttcacaaggacggaaacagctgtgtaactcatgtcgct
gatagcacaaacagcagcttgggttggggtccagactctgtgtctggagaggttgttaca
aacgaagcagaggatgttgaagaacatgcagaaccacacagtgtttctgctgaggaattt
tgtaaaactgaaggaaaaaaacataaaagaaaacgatgtgacagagtttcagctgaagat
cctcagaggccttcatcttctgtaacatttgagcgattggctgatgacagagatcttgct
ggaagtgatttaaaaagtacagacatggggatatcagctcccagttcaagtgttgagaga
gatcctacagtttcactgatgaagtctacaaagcctcgtactaactcaaaacctgctagg
aaagttccggcttctaaggttattaagaaaactcatttagacaccaaaagagtacagaat
aagagttcatgttacatcagttgtagaacatcccctgctattgtgccgccgaagaaatta
cgccagtgtccagagccaacttcaacggttgaaaaacttggcctgaaaaaagctcctcgg
aaggcatttgagttgtcccagaggtctctggagtgtatagtccaattacgtgaccatggt
aagactgttggagtagtcgacgcccccaaaaagactaaattaatttctcctcagactctt
tccatcaaaaataataagaagcttctgacaagtcaggatcttcagtttcaaaggctcatg
agatctagatcacatcagaaacgagaccttgattacactgcaagaacagtgtcacgtgtc
acagtacagggttctgacgtacttgtaccagactctgatgggccagctaatcatagagga
aatgagctccctgccaacagtaatgaaaagcaattagcaaaatgcatgccttccaaatca
gaagtggcaaaagccatttctgatcctcaggtgactgatatagcttatcttgtgaaccag
tgtgagtctagagtgttaagtggaggggtgccaacagatgtgatgctctctactccagag
gagcctgtgggtgaaggtgcacccacagtacaaggtggggaggtggcagctgttaaagct
gctgagccagaatcaagtagtgatacagatgatgacaatttattcctaacccaacatgat
cctcaagatatggatctgtgttcacagatggaagatgatgataaaccgattgtagtggct
cataaagatacagttcagagagaggagtctgtaagtcagccccatttggagtctttgagt
gtcacaaagtgcaagtacaaagactgtgttgaaaccacaagaaaccagagtgaatactgc
ccaagacacgctgaagctaaaacaacagatgacgacgtgtttcgtaaacctggcttacct
attaggtcgtccttgagacctactactaccaagatatttagctcaagcagtgcttcacga
actgccaatctttccaagtctttggaaagtaccatacttcagtcagtactaaaaaataag
tcgagtggggcacagcccaatttgaaggtgacaccacccacttccctggagtctcagaag
ccagtggctgaggtgaaaagtttaagcagtatttttcattttcagactcctagcagttcc
accaaacagagtcacaagcttacacttagtgagaacaagcctaggtcagcttcctctcca
gtgaacattgtcttgccatcgcagtccatctttgacaccttcattaaagaggtcttaaga
tggaaataccaaatgtttttgaactttgataaatgtggtgccccaacaagtctctgtcaa
tccatctcaagacctgtgcccgtccgatttcaagattgtgcagagtattttaatgttttt
ctccctttgattatattgaatgcttttgaaacggtggcacaggaatggttcaactctcca
aataaagagaatttctattatttgcatttacgaaaatttccagccgactataaaaaatac
tgggagtttatgatttacctggaggaatctgaactagctaaacagcttcatccaaaggaa
aatgatctggtgtttttggttcctacgagactaaatagagagaagaaggatatggacagg
aatggcatgcaagatcgaaatggctattactgtggttatgttcataagtttcgtcgtact
tcagtcatgcgcagtggaaaagctgagtgttccttgtgcatccagacacaagataacttg
ccagccagcctaaatgaacttacgaaatgtattgtaatcagttctctggtaactacacag
aggaaattgaaagctatgtctctgttgaacagtcggaaccagttggccagagctgttcta
aatccaaaccccatggacttctgtacaaaagacctattaactacaacatctgaaagaatt
attgcctacttaaaagacttcaatgaagaccagaagaaagccatagaaactgcatatgcc
atggtgaaacactcaccatccgttgccaaaatctgtttgattcatggtccacctggaaca
ggaaaatcaaaaaccattgttggtctcttgtaccgcttattgacagagaaccagaggaag
ggccgttcagatgaaaacttcaatgccaaaatcaagcaaaaccgagtccttgtgtgtgca
ccttccaatgcagctgttgatgaacttatgaaaaaaattatccttgaattcaaagaaaaa
tgtaaagacaagaagaatcctttgggaaattgtggagatataaatttagtacgactgggc
ccagaaaagtctattaatacagaggtcctaaaattcagtttggacagccaagtcaaccac
agaatgaaaaaagacttgccttctcatattcaagaaatgcatagaagaaaagagtttcta
gatggtcaactcgatgagctttctcgccagcgagctctgtgtcgaggtgggcgggagatg
cagaggcaagaattagatggatatattgcccaagtttcaaaagaaaggcaagagcttgct
tcaaaaattaaagaggtccagggacgcccacagaaaacccagaacaccatcatcttggag
tctcacgtcatctgctgcacgttgagcacaagtggcggtttcctgcttgagtctgctttc
cgagggcaggggggcgtcccctttagttgtgtcattgttgatgaggctgggcagtcttgt
gaagtcgagacactttctccacttatccaccgctgcaacaaacttatcctagtaggagac
cccaaacagctccctcccacggtcatttctatgaaagcacaggagtatggctatgaccag
tcgatgatggcacgattctgcaagctacttgaagagaatgtggagcagaacatgattggc
aggctgcctgttttacagcttaccattcagtacaggatgcatccagacatatgtctcttc
ccttctaattatgtttataacaaaaacttgaaaacaaatagatttactgaagccgttcga
tgttcatcagagtggccatttcagccctaccttgtgtttgatgttggagatggttcagaa
cgacgggataatgactcctatataaatgttcaagaaataaagttggtgatggaaatcatt
aaacttattaaagacaaaagaaaagatatttccttccgaaatattggcataataacccat
tacaaggctcagaagacaatgatccagaaggatttggagaaagaatttgataagaaaggt
ttattacagcccatcatgatgggggagtcaaggcagcaggaccctgaagcatccagtcag
aagaagaagagcagtgaatgcatgcatgctagtgatgagcccgatttctccacttttaca
cagtccgggatctcctgcgtagagaatggtgtcacccacactgggcctgcagaagtggat
acagtggatgccttccagggccggcagaaagactgtataattgttacctgtgtcagggcg
agtgctgtgcaagggtcaattggattcctggcaagtttgcagagattgaatgtcaccatt
acacgagccaagtacagcctttttatccttggacatttgaggactctgatggaaaaccaa
cattggaatgaactgattcaggatgctcagaagcgtggggccatcattaagacctctgac
ccaaactatagacatgacgctatgaagattctgaaactgaagcctgtgctgcagaggagt
ctgacccatcctccagccactgccccggaggcacccagacctcagggtggcttgcccagc
aacaagctggacagtggacttgccaggacatcttttgctgcttctctgtaccacacaccc
tctgatgctgtcccttcaaaggaacctgaaaggttgtctcttcaagatcgacttcgagat
ccacgactacataggagatcggatactgaagccaagggaacatttttgaaggatgcacag
cctgcgagccctcagctccctggggtagtccatctcctgggagagcctggctttcctggg
ctttttccggacctgagttttgttgtgccaccatccactgccatcgtcgctcctctgagc
agccacaggtctcctctgcaggctgagccgccacctgctcaccctgctgctccttccacg
agcaggaggaagtacagtgacccaggctctgggttcagtcacagaagagagcccggggcc
ttcggtgaagaggagaggcgggtctctgtgactcaccacatgctgaggagtactaactgg
gacaagagagggctagagcaggaggacagcagtgccaagaagaggcgctttctctag
DBGET
integrated database retrieval system
