KEGG   Peromyscus leucopus (white-footed mouse): 114703046
Entry
114703046         CDS       T07241                                 
Symbol
Akt1
Name
(RefSeq) RAC-alpha serine/threonine-protein kinase
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
pleu  Peromyscus leucopus (white-footed mouse)
Pathway
pleu01521  EGFR tyrosine kinase inhibitor resistance
pleu01522  Endocrine resistance
pleu01524  Platinum drug resistance
pleu04010  MAPK signaling pathway
pleu04012  ErbB signaling pathway
pleu04014  Ras signaling pathway
pleu04015  Rap1 signaling pathway
pleu04022  cGMP-PKG signaling pathway
pleu04024  cAMP signaling pathway
pleu04062  Chemokine signaling pathway
pleu04066  HIF-1 signaling pathway
pleu04068  FoxO signaling pathway
pleu04071  Sphingolipid signaling pathway
pleu04072  Phospholipase D signaling pathway
pleu04140  Autophagy - animal
pleu04150  mTOR signaling pathway
pleu04151  PI3K-Akt signaling pathway
pleu04152  AMPK signaling pathway
pleu04210  Apoptosis
pleu04211  Longevity regulating pathway
pleu04213  Longevity regulating pathway - multiple species
pleu04218  Cellular senescence
pleu04261  Adrenergic signaling in cardiomyocytes
pleu04370  VEGF signaling pathway
pleu04371  Apelin signaling pathway
pleu04380  Osteoclast differentiation
pleu04510  Focal adhesion
pleu04550  Signaling pathways regulating pluripotency of stem cells
pleu04611  Platelet activation
pleu04613  Neutrophil extracellular trap formation
pleu04620  Toll-like receptor signaling pathway
pleu04625  C-type lectin receptor signaling pathway
pleu04630  JAK-STAT signaling pathway
pleu04660  T cell receptor signaling pathway
pleu04662  B cell receptor signaling pathway
pleu04664  Fc epsilon RI signaling pathway
pleu04666  Fc gamma R-mediated phagocytosis
pleu04668  TNF signaling pathway
pleu04722  Neurotrophin signaling pathway
pleu04725  Cholinergic synapse
pleu04728  Dopaminergic synapse
pleu04810  Regulation of actin cytoskeleton
pleu04910  Insulin signaling pathway
pleu04914  Progesterone-mediated oocyte maturation
pleu04915  Estrogen signaling pathway
pleu04917  Prolactin signaling pathway
pleu04919  Thyroid hormone signaling pathway
pleu04920  Adipocytokine signaling pathway
pleu04922  Glucagon signaling pathway
pleu04923  Regulation of lipolysis in adipocytes
pleu04926  Relaxin signaling pathway
pleu04929  GnRH secretion
pleu04931  Insulin resistance
pleu04932  Non-alcoholic fatty liver disease
pleu04933  AGE-RAGE signaling pathway in diabetic complications
pleu04935  Growth hormone synthesis, secretion and action
pleu04936  Alcoholic liver disease
pleu04973  Carbohydrate digestion and absorption
pleu05010  Alzheimer disease
pleu05017  Spinocerebellar ataxia
pleu05132  Salmonella infection
pleu05135  Yersinia infection
pleu05142  Chagas disease
pleu05145  Toxoplasmosis
pleu05152  Tuberculosis
pleu05160  Hepatitis C
pleu05161  Hepatitis B
pleu05162  Measles
pleu05163  Human cytomegalovirus infection
pleu05164  Influenza A
pleu05165  Human papillomavirus infection
pleu05166  Human T-cell leukemia virus 1 infection
pleu05167  Kaposi sarcoma-associated herpesvirus infection
pleu05168  Herpes simplex virus 1 infection
pleu05169  Epstein-Barr virus infection
pleu05170  Human immunodeficiency virus 1 infection
pleu05200  Pathways in cancer
pleu05205  Proteoglycans in cancer
pleu05207  Chemical carcinogenesis - receptor activation
pleu05208  Chemical carcinogenesis - reactive oxygen species
pleu05210  Colorectal cancer
pleu05211  Renal cell carcinoma
pleu05212  Pancreatic cancer
pleu05213  Endometrial cancer
pleu05214  Glioma
pleu05215  Prostate cancer
pleu05218  Melanoma
pleu05220  Chronic myeloid leukemia
pleu05221  Acute myeloid leukemia
pleu05222  Small cell lung cancer
pleu05223  Non-small cell lung cancer
pleu05224  Breast cancer
pleu05225  Hepatocellular carcinoma
pleu05226  Gastric cancer
pleu05230  Central carbon metabolism in cancer
pleu05231  Choline metabolism in cancer
pleu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pleu05415  Diabetic cardiomyopathy
pleu05417  Lipid and atherosclerosis
pleu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pleu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114703046 (Akt1)
   04012 ErbB signaling pathway
    114703046 (Akt1)
   04014 Ras signaling pathway
    114703046 (Akt1)
   04015 Rap1 signaling pathway
    114703046 (Akt1)
   04370 VEGF signaling pathway
    114703046 (Akt1)
   04371 Apelin signaling pathway
    114703046 (Akt1)
   04630 JAK-STAT signaling pathway
    114703046 (Akt1)
   04668 TNF signaling pathway
    114703046 (Akt1)
   04066 HIF-1 signaling pathway
    114703046 (Akt1)
   04068 FoxO signaling pathway
    114703046 (Akt1)
   04072 Phospholipase D signaling pathway
    114703046 (Akt1)
   04071 Sphingolipid signaling pathway
    114703046 (Akt1)
   04024 cAMP signaling pathway
    114703046 (Akt1)
   04022 cGMP-PKG signaling pathway
    114703046 (Akt1)
   04151 PI3K-Akt signaling pathway
    114703046 (Akt1)
   04152 AMPK signaling pathway
    114703046 (Akt1)
   04150 mTOR signaling pathway
    114703046 (Akt1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    114703046 (Akt1)
  09143 Cell growth and death
   04210 Apoptosis
    114703046 (Akt1)
   04218 Cellular senescence
    114703046 (Akt1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    114703046 (Akt1)
   04550 Signaling pathways regulating pluripotency of stem cells
    114703046 (Akt1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    114703046 (Akt1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    114703046 (Akt1)
   04613 Neutrophil extracellular trap formation
    114703046 (Akt1)
   04620 Toll-like receptor signaling pathway
    114703046 (Akt1)
   04625 C-type lectin receptor signaling pathway
    114703046 (Akt1)
   04660 T cell receptor signaling pathway
    114703046 (Akt1)
   04662 B cell receptor signaling pathway
    114703046 (Akt1)
   04664 Fc epsilon RI signaling pathway
    114703046 (Akt1)
   04666 Fc gamma R-mediated phagocytosis
    114703046 (Akt1)
   04062 Chemokine signaling pathway
    114703046 (Akt1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    114703046 (Akt1)
   04922 Glucagon signaling pathway
    114703046 (Akt1)
   04923 Regulation of lipolysis in adipocytes
    114703046 (Akt1)
   04920 Adipocytokine signaling pathway
    114703046 (Akt1)
   04929 GnRH secretion
    114703046 (Akt1)
   04915 Estrogen signaling pathway
    114703046 (Akt1)
   04914 Progesterone-mediated oocyte maturation
    114703046 (Akt1)
   04917 Prolactin signaling pathway
    114703046 (Akt1)
   04926 Relaxin signaling pathway
    114703046 (Akt1)
   04935 Growth hormone synthesis, secretion and action
    114703046 (Akt1)
   04919 Thyroid hormone signaling pathway
    114703046 (Akt1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    114703046 (Akt1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    114703046 (Akt1)
  09156 Nervous system
   04725 Cholinergic synapse
    114703046 (Akt1)
   04728 Dopaminergic synapse
    114703046 (Akt1)
   04722 Neurotrophin signaling pathway
    114703046 (Akt1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    114703046 (Akt1)
  09149 Aging
   04211 Longevity regulating pathway
    114703046 (Akt1)
   04213 Longevity regulating pathway - multiple species
    114703046 (Akt1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114703046 (Akt1)
   05205 Proteoglycans in cancer
    114703046 (Akt1)
   05207 Chemical carcinogenesis - receptor activation
    114703046 (Akt1)
   05208 Chemical carcinogenesis - reactive oxygen species
    114703046 (Akt1)
   05230 Central carbon metabolism in cancer
    114703046 (Akt1)
   05231 Choline metabolism in cancer
    114703046 (Akt1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    114703046 (Akt1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    114703046 (Akt1)
   05212 Pancreatic cancer
    114703046 (Akt1)
   05225 Hepatocellular carcinoma
    114703046 (Akt1)
   05226 Gastric cancer
    114703046 (Akt1)
   05214 Glioma
    114703046 (Akt1)
   05221 Acute myeloid leukemia
    114703046 (Akt1)
   05220 Chronic myeloid leukemia
    114703046 (Akt1)
   05218 Melanoma
    114703046 (Akt1)
   05211 Renal cell carcinoma
    114703046 (Akt1)
   05215 Prostate cancer
    114703046 (Akt1)
   05213 Endometrial cancer
    114703046 (Akt1)
   05224 Breast cancer
    114703046 (Akt1)
   05222 Small cell lung cancer
    114703046 (Akt1)
   05223 Non-small cell lung cancer
    114703046 (Akt1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    114703046 (Akt1)
   05170 Human immunodeficiency virus 1 infection
    114703046 (Akt1)
   05161 Hepatitis B
    114703046 (Akt1)
   05160 Hepatitis C
    114703046 (Akt1)
   05164 Influenza A
    114703046 (Akt1)
   05162 Measles
    114703046 (Akt1)
   05168 Herpes simplex virus 1 infection
    114703046 (Akt1)
   05163 Human cytomegalovirus infection
    114703046 (Akt1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    114703046 (Akt1)
   05169 Epstein-Barr virus infection
    114703046 (Akt1)
   05165 Human papillomavirus infection
    114703046 (Akt1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    114703046 (Akt1)
   05135 Yersinia infection
    114703046 (Akt1)
   05152 Tuberculosis
    114703046 (Akt1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    114703046 (Akt1)
   05142 Chagas disease
    114703046 (Akt1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    114703046 (Akt1)
   05017 Spinocerebellar ataxia
    114703046 (Akt1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114703046 (Akt1)
   05418 Fluid shear stress and atherosclerosis
    114703046 (Akt1)
   05415 Diabetic cardiomyopathy
    114703046 (Akt1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    114703046 (Akt1)
   04932 Non-alcoholic fatty liver disease
    114703046 (Akt1)
   04931 Insulin resistance
    114703046 (Akt1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    114703046 (Akt1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    114703046 (Akt1)
   01524 Platinum drug resistance
    114703046 (Akt1)
   01522 Endocrine resistance
    114703046 (Akt1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pleu01001]
    114703046 (Akt1)
Enzymes [BR:pleu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     114703046 (Akt1)
Protein kinases [BR:pleu01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   114703046 (Akt1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 PH_11 Seadorna_VP7
Other DBs
NCBI-GeneID: 114703046
NCBI-ProteinID: XP_028739534
LinkDB
Position
14:complement(79844244..79865150)
AA seq 480 aa
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVEQRESPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEETMDF
RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKK
LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
NT seq 1443 nt   +upstreamnt  +downstreamnt
atgaacgacgtagcaattgtgaaggagggctggctacacaaacgaggggaatacattaag
acctggcggccacgctacttcctcctcaagaatgatggcacctttattggctacaaggag
cggcctcaggatgtggagcagcgggagtctccccttaacaacttctcagtggcacaatgc
cagctgatgaagacagagcggccgaggcccaacacgttcatcatccgctgcctgcagtgg
accacagtcattgagcgcaccttccacgtggaaacgccggaggagcgggaagagtggacc
actgccatccagactgtggctgatggactcaagaggcaggaggaagagacgatggacttc
cgatcaggttctcccagcgacaactcgggggctgaggagatggaggtgtccctggccaag
cccaagcaccgtgtgaccatgaacgagtttgagtacctgaagctgctgggcaagggcacc
tttgggaaggtgatcctggtgaaggagaaggccacgggccgctactatgccatgaagatc
ctcaagaaggaggtcatcgtcgccaaggatgaggttgcccacaccctcactgagaaccgt
gtcctgcagaactccaggcatcccttccttacagccctgaagtactcattccagacccat
gaccgcctctgctttgtcatggaatatgccaatgggggcgagcttttcttccacttgtct
cgtgagcgcgtgttttccgaggaccgggcccgcttctacggtgcggagattgtgtcggcc
ctggactatctgcactctgagaagaacgtggtataccgggacctcaagctggagaacctc
atgctggacaaggatgggcacatcaagataacggacttcggactgtgcaaggagggtatc
aaggatggcgccaccatgaagaccttctgcgggacccccgagtacctggcccctgaggtg
ctggaggacaacgactatggccgtgcagtggattggtgggggctgggcgtggtcatgtat
gagatgatgtgtggccgcctgcccttctacaaccaggaccatgagaaactgttcgagctc
atcctcatggaggaaatccgcttcccgcgcacgcttggccctgaggccaagtccctgctg
tctgggctgctcaagaaggaccccacgcagaggcttggcgggggctccgaggatgccaag
gagatcatgcagcaccgcttctttgccaacatcgtgtggcaagatgtgtatgagaagaag
ctgagcccgcctttcaagccccaggtcacctctgagactgacaccaggtatttcgatgag
gagttcacagctcagatgatcactatcacaccgcctgatcaagatgacagcatggagtgt
gtggacagcgaacggaggccgcacttcccccagttctcctactcggccagtggcacggcc
tga

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