Peromyscus leucopus (white-footed mouse): 114703812
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Entry
114703812 CDS
T07241
Symbol
Fpgs
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00790
Folate biosynthesis
pleu01100
Metabolic pathways
pleu01240
Biosynthesis of cofactors
pleu01523
Antifolate resistance
pleu04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
114703812 (Fpgs)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
114703812 (Fpgs)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
114703812 (Fpgs)
Enzymes [BR:
pleu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
114703812 (Fpgs)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
114703812
NCBI-ProteinID:
XP_028740570
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Position
4:6635059..6655965
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AA seq
590 aa
AA seq
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MSWARSHLRSALSLAAVSARGATAEGAARRWLSAWPAPQEPGMEYQDAVRMLNTLQTNAS
YLEQVKRQRSDPQAQLEAMEVYLVRSGLQVEDLNSLNIIHVTGTKGKGSTCAFTERILRN
YGLKTGFFSSPHLVQVRERIRINGKPISPELFTKHFWRLYHQLEKFKDDSHISMPAYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
WQKGGIFKPGVPAFTVLQPEGPLAVLRDRAQQTSCPLYLCPPLEALEEGGLPLPLGLEGE
HQRSNAALALQLARSWLEQRDHQDVRELTVSRPGTRGQLPLAPVFRPTSHMRHGLRDTEW
LGRTQVLRRGPLTWYLDGAHTTSSMQACARWYCQSLQRSKRPSGGPQVHVLLFNSTGDRD
SAALLKLLQPCRFDYAVFCPNLTEVSSTENADQQNFTVTLDQVLLRCLQHQQHWSCLAEK
EAGPDLWSGPGGGAEPGGPGGSQLLALHPLHSASTDSLVFSCISHALQWISQGRDPIFQP
PTPLRSLLSHPTASSGASILREAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1773 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtgggcgcggagccacctgcgctcggctctgtccctggcagctgtttctgcgcgt
ggtgcaacggccgagggcgcggcgcggcggtggttgagcgcgtggcccgcgccgcaggag
cccggcatggagtatcaggatgctgtgcgcatgctcaacaccctgcagaccaatgccagc
tacctggagcaggtgaagcgtcagcggagtgaccctcaggcgcagctggaagccatggag
gtgtacctggtacggagtggactgcaggtggaggacctaaacagcctaaacattatccac
gtcactgggaccaaaggaaagggctccacctgtgccttcactgaacgcatcctgcggaac
tacggcctgaagacaggcttctttagctctccccacctggtacaggtgcgtgaacggatt
cgcatcaatgggaagcccatcagtcccgaacttttcaccaagcacttctggcgtctctat
caccagctggagaagttcaaggatgacagccacatttccatgcctgcttacttccgcttc
ctcacactcatggccttccatgtcttcctccaagagaaggtggacctggctgtggtagaa
gtgggcattggcggggcttatgactgcaccaacatcatcagaaagccagtggtgtgtgga
gtgtcctctcttggtattgaccacaccagcctgctaggagacacggtggagaagatagcc
tggcagaaagggggcatctttaagcctggtgtccctgcctttactgtgctacagccggaa
ggtcccctggccgtgctgagagatcgagctcagcagacctcatgtcccctgtacctgtgt
ccaccgttagaagccctggaggagggtgggctgccgctgcccctgggcctggagggagag
caccagcggtccaatgcagccttagccttgcagctggcccgtagttggctggagcagcgg
gaccaccaggacgtccgggagctgacggtgtccaggccaggcacacgggggcagctgcct
ctggcacctgtgttccgtcccacctctcacatgagacatgggcttcgggacacggagtgg
cttggccggacacaggtgctgcggcggggacctctcacctggtacctggacggcgcacac
accaccagcagtatgcaggcctgcgcgcgctggtattgccagtcattacagcgcagtaaa
cgccccagtggtgggcctcaagtacacgtcttgctcttcaactccaccggtgacagggac
tctgccgctctgctgaagctgctgcagccctgccggtttgactacgccgtcttctgcccc
aacctgacagaggtgtcatccacagaaaacgcagaccagcagaacttcacggtgactctg
gaccaggtgctgctccgctgcctccaacaccagcaacactggagctgcctggccgagaaa
gaagccggccccgacctctggagcggccccggcggcggcgcagagcccggtggaccgggg
ggctcccagctgctggcgctacacccactgcactctgctagcacggactccctagttttt
agctgcatctcccacgccctgcagtggatcagccaaggccgggatcccatctttcaaccc
ccgacccccctgaggagcctcctcagccaccccacagccagcagtggggcaagcattctg
cgtgaggctgccgccatccatgtactggttacggggagcctgcacctggtgggtggagtc
ctaaagctgctggagccttccctgtcccagtag
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