Peromyscus leucopus (white-footed mouse): 114704793
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Entry
114704793 CDS
T07241
Symbol
Shmt2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00260
Glycine, serine and threonine metabolism
pleu00630
Glyoxylate and dicarboxylate metabolism
pleu00670
One carbon pool by folate
pleu01100
Metabolic pathways
pleu01200
Carbon metabolism
pleu01230
Biosynthesis of amino acids
pleu01240
Biosynthesis of cofactors
pleu01523
Antifolate resistance
pleu04981
Folate transport and metabolism
Module
pleu_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
114704793 (Shmt2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
114704793 (Shmt2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
114704793 (Shmt2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
114704793 (Shmt2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
114704793 (Shmt2)
Enzymes [BR:
pleu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
114704793 (Shmt2)
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Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
114704793
NCBI-ProteinID:
XP_028742051
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Position
18:2981896..2987176
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AA seq
504 aa
AA seq
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MVSFSLLWTSRPLQRCGQLVWTAARAQHSKVARTQAGEASGGWTGQETLADSDPEVWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPQTGLIDYDQLAATARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKYADIVTTTTHKTLRGARSGLIFYRKGVRTVD
PKTGQEIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLRNAQA
MADALLKRGYSLVSGGTDTHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKRKTAKLQDFKSFLLKDPETSQ
RLASLRQQVEQFARTFPMPGFDER
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atggtgtccttctctctgctgtggaccagtcggcctctgcagagatgtggtcagctggtc
tggacggctgctcgggcccagcacagcaaggtggcccggacacaggccggggaagcatct
ggaggctggacaggccaggagactctggcagacagtgaccctgaggtgtgggagctcctg
cagagggagaaggacaggcagtgtcgtggtctggaactcatcgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatactatggcggcgcggaggtcgtggatgagatcgagctgctctgccag
cgccgggccctggaagccttcgacctggatccggcacagtggggagtcaacgtccagcca
tactcggggtccccagccaatctggcggcctacacagctctccttcagccccatgaccga
atcatggggctggacctacccgatgggggccacctcacccacggctacatgtctgacgtc
aaacggatctccgccacatccattttcttcgagtctatgccctacaagctcaacccccag
accggcctcatcgactacgaccagctggcggcgaccgctcggctcttccgaccgcggctc
atcatagccggtactagtgcctacgcccgcctcattgactatgcccgcatgagagaggtg
tgcgatgaggtcaaggcacacctgctggcggacatggcccatatcagtggcctcgtggcc
gccaaggtgatcccctcgcctttcaagtacgcggacatcgtcaccaccaccacccacaag
actcttcgaggggccaggtcagggctcatcttttaccggaaaggagtgcggaccgtagac
cccaagaccggccaagagatcccttacacttttgaggaccgaatcaactttgctgtgttc
ccatccttacaggggggcccccacaaccacgccattgctgcggtagctgtggccctcaag
caggcctgcacccccatgttccgggagtactccttacaggtgctgaggaatgctcaggcc
atggccgatgcgctgctaaagcgaggctactcgctggtgtctggtggcaccgacacccac
ctggtgctggtggacctgcgacccaagggcctggatggcgcgcgcgccgagcgcgtgctg
gaactcgtgtccatcacggccaacaagaacacctgtcccggagaccggagcgccatcacc
cccgggggcctgaggctgggcgccccagcgttgacttctcggcagttccgtgaggatgac
ttccggagggtcgttgattttatcgatgaaggagtcaacattggcttggaggtgaagcgc
aagactgccaagctccaggatttcaaatccttcctcctcaaggacccagaaacaagtcag
cgtctggccagcctcaggcaacaggtggagcagtttgccaggaccttcccgatgcccgga
ttcgatgaacgctga
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