Peromyscus leucopus (white-footed mouse): 114704843
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Entry
114704843 CDS
T07241
Symbol
Mylk
Name
(RefSeq) myosin light chain kinase, smooth muscle isoform X1
KO
K00907
myosin-light-chain kinase [EC:
2.7.11.18
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu04020
Calcium signaling pathway
pleu04022
cGMP-PKG signaling pathway
pleu04270
Vascular smooth muscle contraction
pleu04371
Apelin signaling pathway
pleu04510
Focal adhesion
pleu04611
Platelet activation
pleu04810
Regulation of actin cytoskeleton
pleu04921
Oxytocin signaling pathway
pleu04971
Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
114704843 (Mylk)
04020 Calcium signaling pathway
114704843 (Mylk)
04022 cGMP-PKG signaling pathway
114704843 (Mylk)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
114704843 (Mylk)
09142 Cell motility
04810 Regulation of actin cytoskeleton
114704843 (Mylk)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
114704843 (Mylk)
09152 Endocrine system
04921 Oxytocin signaling pathway
114704843 (Mylk)
09153 Circulatory system
04270 Vascular smooth muscle contraction
114704843 (Mylk)
09154 Digestive system
04971 Gastric acid secretion
114704843 (Mylk)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pleu01001
]
114704843 (Mylk)
Enzymes [BR:
pleu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.18 myosin-light-chain kinase
114704843 (Mylk)
Protein kinases [BR:
pleu01001
]
Serine/threonine kinases: CAMK group
MLCK family
114704843 (Mylk)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
I-set
Ig_3
ig
Ig_2
Pkinase
23ISL
V-set
PK_Tyr_Ser-Thr
C2-set_2
fn3
Ig_C17orf99
Ig_DSCAM-DSCAML_C
Kinase-like
Kdo
ATP19
AvrM_N
DUF5898
Tissue_fac
Motif
Other DBs
NCBI-GeneID:
114704843
NCBI-ProteinID:
XP_028742158
LinkDB
All DBs
Position
12:complement(60809087..60991354)
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AA seq
1972 aa
AA seq
DB search
MGDMKLVASSHMSKTSHGVDPSRVSSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
EPQVTWHRNGQTITPGGRFLLDCGVRGTFSLVIHTVREEDSGKYTCEASNSGGARQVTVE
LTVEGNLTKKHGQPAVSKASGFSSPAGETRPSIWGECPPKFATKLGRAVVKEGQMGRFSC
KITGRPPPQVTWLKENVPLQPSARVAMSEKNGMQILEIHEVTRDDMGVYTCMVVNGSGKA
SMSAELSIPGLDNATRTFVRATKAPSPDIRKEVTNGVSKDPETVAGSENRSSPQRSVSSA
WATHSHLKSLQEPELKLCEGSPRKALQSSVLQKTSSTITLQAAKVQPEARAPGFRAFSPG
EERKSLAAPQQATLPTRQCGLGGPVGNKLGTRNISIESPRESTFPKFESQPQSQEVTEDQ
TVKFICEVSGIPKPEVAWFLEGVPVRRREGVIEIYEDGASHYLCLRRARMRDSGSYSCTA
SNILGHVSCSWTLLVERSNLAQTAPSFSSVLKDSVVIEGQDLVLRCSVRGTPVPRITWLL
NGRPIKFAHSICEAGMAELHIQDALPEDRGTYTCLAENALGQVSCSARVTVQEKKSEGER
ECLLPRAPSKPMAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGHEIQESEDF
HFEQKGGRHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAMLTVQEPHDGTQPWFISKPRS
VTASLGQSVLISCAIAGDPFPTVLWLRDGKALSKDTGHFELLQNEDVFTLVLKDVQPWHA
GQYEILLKNRVGECSCQVSLMLHNSPARAPPRGREPAGCEGLCSGGVGAHGDGDRDGTLR
PGWPARGQGWPEEDDGDDDDVRGLLKRRVETRLHTEEAIRQQEVGQLDFRDLLGRKVSTK
TVSEEDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTPKTPIP
EKAPPPKAATPDFRSVLGSKKKSPTENGSDNAGENPTPVGSTQPVGALKATGNAKPAETL
KATGNAKPAETLKPTGNAKPAETLKPTGNAKPAETLKPAGNAKPAETLKHAGNAKPAETL
KPIANTQPAGSLKPIGNAQPTETPKPVANAKPAEPLKPAGKEEPKEVKNDVNCKKGHAGA
TGIEKRPESQGSAPVFKEKLQDVHVAEGEKLLLQCQVTSDPPAAVTWTLNGKTLKTTKFI
ILSQEGSLFSISIEKALPEDKGLYKCVAKNSAGQAECSCQVTVDDARAGENTKVPEMKSR
RPKGSLPPLLGTESDATVKKKPAPKTPTKAAMPPQITQFPEDQKVRAGEPVELFGKVTGT
QPITCTWMKFRKQIQESEHIKVETSEGGSKLTILAARQEHCGCYTLVVENKLGSRQAQVN
LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYNVEIWDTEDKMWKELATC
RSTSFNVQDLLPDREYKFRVRAVNVYGTSEPSQESELTAVGEKPEEPKDEVEVSDDDEKE
PEVDYRTVTVNTEQKVSDVYDIEERLGSGKFGQVFRLVEKKTRKIWAGKFFKAYSAKEKE
NIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIK
YMKQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGT
PEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEA
FDEISDDAKDFISNLLKKDMKNRLNCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRK
WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPINAEKLESEEDVSQAFLEAVAEEK
PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN
CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGGEEEEEE
NT seq
5919 nt
NT seq
+upstream
nt +downstream
nt
atgggggacatgaaactggttgcctcgtcacacatgtccaaaacctcccacggtgtggat
ccctcgagggtcagctccatgcccctcacggaggcccctgctttcattctgccccctcgg
aacctctgcatcaaagaaggagccaccgccaagttcgaagggagggtccggggctaccca
gagccccaggtgacatggcacagaaatgggcaaaccatcacccccgggggccgcttcctg
ctggactgtggagtgcgggggactttcagcctggtgattcacacggtgcgtgaggaggac
agcgggaagtatacctgtgaagccagcaacagcggtggtgcccgccaggtgacagtggag
ctgaccgtggaagggaatcttacgaagaagcatggccagcctgctgtttccaaagcctca
ggattttcatccccagcaggggagactcgtcctagcatctggggcgagtgcccaccgaag
tttgccaccaagttgggccgagctgtggtcaaagaagggcagatggggcgattctcctgc
aagatcactggccggcctccaccacaggtcacctggctcaaggaaaatgtcccgttgcag
ccaagtgcccgtgtggctatgtcggagaagaatggtatgcagatcctggaaatccatgag
gtcactcgggatgacatgggcgtgtacacatgcatggtggtgaacgggtcagggaaagcc
tccatgtctgcggaactctccatcccaggtttggacaatgccactaggacgtttgtgaga
gcaaccaaggcccccagtccagacatcaggaaggaggtgaccaatggagtctccaaggac
cccgagactgtggccggaagtgagaaccgctcaagcccccagaggagtgtctcctcagcc
tgggccacacacagccacctgaagtccctgcaggagcccgagctgaaactgtgtgagggt
tcgcccagaaaggccctgcagtcctcagtcctgcagaagacttccagcaccattaccctg
caggctgccaaagtccagccagaagcgagagcaccaggcttccgggccttctctcctggg
gaagagaggaaaagtctggctgcccctcagcaagccacactccctaccagacagtgtggc
ctgggaggcccagttgggaacaaattgggtaccaggaacatctccatagagagcccaagg
gagtcgacattccccaaatttgagagtcagccccaaagccaagaagtcactgaagatcag
acagtcaagttcatctgtgaggtttcagggatcccaaagcctgaagtggcctggttcctg
gaaggcgtccctgtgaggagacgggaaggcgttattgagatttatgaagacggtgcatcc
cattacctctgcctgcggagagcccggatgagggacagtgggagttacagctgtacagcc
tccaacatccttggccatgtgtcctgcagttggaccctcctggtggaacggtcaaacttg
gcacagacggccccttcattctccagcgtcctgaaggacagtgttgtcattgagggccag
gacttggtgctgcggtgctctgtaagggggaccccggtaccccggatcacttggctgctc
aatgggcggcccatcaagtttgctcactccatctgtgaggctggcatggctgagctccac
atccaggatgccctgccagaggaccgcgggacctacacctgtctggctgagaatgccctg
ggacaggtgtcctgcagcgccagggtcaccgtccaagaaaagaaaagtgaaggcgagagg
gaatgccttctgccacgagcgcccagcaagcccatggcacccatcttcctgcaaggcctc
tctgatctcaaagtcatggatggaagccaggtcactatgaccgtccaggtgtcagggaac
ccacctccagaagtgatatggcttcacaatggacatgagatccaggagtcagaggacttc
cactttgagcagaaaggtggccggcacagcctgtgcatccaggaggtgttcccagaggac
acgggcacatacacctgtgaggcctggaacagtgcaggggaagtccgcacccaggccatg
ctcaccgtgcaagaacctcatgacggcacccagccctggttcatcagcaagcctcgttca
gtgacagcctccctgggccagagtgtcctcatctcctgtgccatagctggagaccccttc
cccactgtgctctggctccgagatggcaaagccctctccaaggacactggccactttgag
ctgctccagaatgaggacgtgttcaccttggtcctaaaggacgtgcagccctggcatgcc
ggccagtatgagatcctgctcaagaaccgggttggcgagtgtagttgccaggtgtccctg
atgctgcacaacagtccggccagagccccgccacgggggcgggagcctgccggctgcgag
ggcctctgtagtggaggagttggtgctcatggtgatggtgaccgtgatgggaccctgagg
cctggctggccagcaagagggcagggttggccagaggaggacgacggagacgacgacgac
gtgagggggctgctgaagagacgggtggagaccaggctgcacaccgaagaggccatccgc
cagcaggaggtggggcagttggacttccgtgacctcctgggaaggaaggtgagcaccaag
accgtctctgaagaagacctgaaggagatcccagccgagcagatggatttccgcgccaac
ctccagcggcaagtgaagcccaagaccgtgtccgaggaggagaggaaggtgcacagcccc
cagcaggtcgacttccgctcggtcctagccaagaaggggacccctaagacccccatcccg
gagaaggccccacctcccaaggctgccaccccagactttcgctcggtgttaggcagcaag
aagaagtcacccacggagaacggcagtgacaatgctggggaaaacccgactcctgtaggc
agtacacagccagtcggggccctgaaagccacaggcaatgccaagcccgctgagaccctg
aaagccacaggcaatgccaagcctgctgagaccctgaaacccacaggcaatgccaagcct
gctgagaccctgaaacccacaggcaatgccaagcctgctgagaccctgaaacccgcaggc
aatgccaagcccgcggagaccctgaaacacgcaggcaatgccaaacccgcagagaccctg
aaacccatagccaacacacagcctgcagggtccctgaaacccataggcaatgcacagcct
actgagaccccgaagcccgtggccaatgccaagcctgcagagcccctgaaaccagctggg
aaagaagaacccaaggaggttaagaatgatgtgaactgtaagaaagggcatgccggagcc
acaggcattgaaaagagacccgagagccaaggctcagccccagtcttcaaggaaaagcta
caagacgtccatgtggccgagggtgagaaactgctactccagtgccaagtgacctctgat
cccccggccgctgtcacctggacactgaatggaaagacactcaagaccacaaaattcatc
atcctctcccaagaaggctcactcttctccatctccatcgagaaggcactgcctgaggac
aagggcttgtacaagtgtgtcgccaagaacagcgctggccaggccgagtgctcctgccaa
gtcactgtggatgatgctcgggccggtgagaacaccaaggtcccggagatgaaatcccgg
agacccaagggctctcttccccctctgctaggaacagagagtgatgcaaccgtgaaaaag
aaacctgcccccaagacacctacaaaagcagctatgccccctcagatcacccagttcccc
gaggaccagaaggtacgcgcaggggagcccgtggagctgtttgggaaagtgactggtacc
cagcccatcacctgcacatggatgaagttccgaaagcagatccaggagagcgagcacatc
aaggtggagaccagtgagggcggcagcaagctcaccatcctggcggcgcgccaggagcac
tgtggctgctacacgctggtggtggagaacaagctgggcagcaggcaggcccaggtcaac
ctcacagtcgtggataagccagaccccccagctggcacaccttgtgcttctgacatacgg
agttcctcgctgaccctgtcctggtatggctcttcatatgatggcggcagtgccgtacag
tcctacaatgtggagatctgggacactgaggacaagatgtggaaagaactagccacatgc
cgcagcacctcttttaatgtccaagacctgctgcctgaccgcgagtataaattccgagta
cgtgcagtcaacgtctatggaaccagcgagccaagccaggagtctgagctcacagccgtg
ggagagaaacctgaggagccaaaggatgaagtggaagtgtcagatgatgacgaaaaggaa
cccgaggtcgattatcggacagtgacggttaacactgaacagaaagtctctgatgtgtat
gacattgaagagcgactgggatctgggaagtttggacaagtcttccgacttgtggaaaag
aaaaccagaaaaatctgggccgggaagttcttcaaggcctattccgccaaggagaaagag
aacatccgccaggagatcagcatcatgaactgcctccaccaccccaagctggtccagtgt
gtggatgccttcgaagaaaaggccaacatcgtcatggtcctggagatcgtatcaggcggt
gagctgtttgagcgcatcatcgacgaggacttcgagctgacggagcgagagtgcatcaag
tacatgaagcagatttcggaaggggtggagtacatccacaagcagggcattgtgcatctg
gacctcaagcccgagaacatcatgtgtgtcaacaagaccggcaccaggatcaagctcatt
gacttcgggctggcacgaagactagagaatgccgggtctctgaaggtcctctttgggacc
ccagagtttgtggctcccgaagtgatcaactacgaacccatcggctatgccacagacatg
tggagcatcggggtcatctgctacatcctggtcagcggactgtcccccttcatgggcgac
aatgacaatgagaccttagccaacgtcacttcggccacctgggactttgatgatgaggcg
ttcgatgagatctccgacgatgccaaggatttcatcagtaacctgctgaagaaagatatg
aaaaaccgtctgaactgcacccaatgccttcagcacccatggctgatgaaggacaccaag
aacatggaggccaagaagctgtccaaggaccggatgaagaagtacatggcaagaagaaag
tggcagaaaacgggcaatgctgtgagagccatcggaagactctcctctatggcaatgata
tcagggctcagtggcaggaaatcctcgacagggtcaccgaccagcccgatcaatgcagag
aaactagagtccgaagaagatgtctcccaggctttcctcgaggctgttgctgaggaaaag
ccccatgtaaagccctatttctctaagaccattcgtgatctggaagttgtggaaggaagt
gcggctagatttgactgcaagattgaaggttacccagaccccgaggttgtctggttcaag
gatgaccagtccatcagggagtcccgccacttccagatagactatgatgaagatgggaac
tgctctctgatcatcagcgacgtttgcggggatgatgacgccaagtacacctgcaaggct
gtcaacagcctgggagaagccacctgcactgccgagctcatcgtggaaaccatggaggag
ggggagggggaggggggagaggaagaggaggaagagtga
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