Peromyscus leucopus (white-footed mouse): 114706976
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Entry
114706976 CDS
T07241
Symbol
Top2a
Name
(RefSeq) LOW QUALITY PROTEIN: DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
114706976 (Top2a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pleu03032
]
114706976 (Top2a)
03036 Chromosome and associated proteins [BR:
pleu03036
]
114706976 (Top2a)
Enzymes [BR:
pleu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
114706976 (Top2a)
DNA replication proteins [BR:
pleu03032
]
Eukaryotic type
DNA Topoisomerases
114706976 (Top2a)
Chromosome and associated proteins [BR:
pleu03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
114706976 (Top2a)
Centrosome formation proteins
Centriole proteins
114706976 (Top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
114706976
NCBI-ProteinID:
XP_028745388
LinkDB
All DBs
Position
8b:93445439..93477476
Genome browser
AA seq
1526 aa
AA seq
DB search
MELSPLQPVNENMQMNKKKNEDAKKRMSIERIYQKKTQLEHILLRPDTYIGSVELVTQQM
WVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNN
GKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVET
ASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMVR
RAYDVAGSTKDVKVFLNGNRLPVKGFRSYVDMYLKDKLDETGNALKVVHEQVNPRWEVCL
TMSEKGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGVAVKAHQVKNHMW
IFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQI
QLNKKCSAVKHNRIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDKY
GVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTD
QDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSS
TPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQVDDR
KEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSXPSMVDG
LKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNL
NLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLTRLLFPPKDDHTLKFLYDDNQRVEPEWY
IPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLPMLPSYKNFKGTIEE
LASNQYVINGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYH
TDTTVRFVIKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILKD
FFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRG
YDSDPVKAWKEAQQKVPDEEENEESDNENNDSVPESGPTFNYLLDMPLWYLTKEKKDELC
KQRNEKEQELNTLKKKSPSDLWKEDLAVFIEELEVVEAKEKQDEQVGLPGKGGKAKGKKG
QVSEVLPSPGGKRVIPHVTMEMKAEAEKKIRKKIKSENAEGTPAEDGLELGGLKQRLAKK
QKKEPDTMAKKQTTLPFKPIKKGKKRNPWSDSESDMSSNESNFDVPPREKDPRRAATKAK
FTVDLDSDEDFSGFEEKDEDEDFFPLDTSPPKTKIPPKNRTKTLKTQKSTTSVADLESDV
QDSVPASPSPPAADVPAEKEQLKPSSKQTAASKKTVTKSQSSTSTAGTKKRAAPKATKSD
STLSVHGPEKPDPAKAKSNRKRKQSSDDSDSDFEKVVSKAATSKKLKGETQDFHVDLDET
VAPRAKSGRARKPIKYLEESDEDDLF
NT seq
4581 nt
NT seq
+upstream
nt +downstream
nt
atggagctgtcaccgctgcagcctgtaaatgaaaatatgcaaatgaacaaaaagaaaaat
gaagatgccaagaaaagaatgtctattgaaagaatctatcagaaaaaaacacaactggag
catatactgctccgcccggatacctacattggctccgtggaactagttacccagcaaatg
tgggtttacgatgaagatgttggcattaactatagggaagtaacttttgttcctggtttg
tataaaatctttgatgaaattctagttaatgctgcagacaacaaacaaagggaccccaag
atgtcctgtattagagtcacaatcgatccagaaaataatttaattagcatatggaataat
ggaaaaggaattcctgttgttgaacacaaagttgagaaaatgtatgtcccagctctcata
tttggacagctcttaacctctagtaactatgacgatgatgaaaagaaagtaacaggtggt
cgcaatggctatggagccaaactgtgtaacatattcagcaccaaatttactgtggaaaca
gccagtagagaatacaagaaaatgttcaaacagacatggatggataacatggggagagct
ggtgaaatggaactcaagccctttaatggagaagattatacatgcattaccttccagcct
gatttatcgaagtttaaaatgcaaagcctagacaaagatattgttgcactgatggttaga
agagcatatgatgttgctggttccactaaagatgtcaaagtctttcttaatggaaataga
ctgccagtcaaagggttccgcagctatgtggacatgtacttgaaggataagttagatgaa
accggtaacgcactgaaagtagtgcatgagcaagtcaatccacggtgggaagtgtgctta
acaatgagtgaaaagggcttccagcaaattagctttgtcaacagcattgctacttctaag
ggtggcagacatgttgattatgtagctgatcagattgtgagtaaactggtggatgtggtg
aaaaagaagaacaagggtggtgtcgcagtgaaagcacaccaggtgaaaaatcacatgtgg
atttttgtaaatgccttgattgaaaacccaacatttgactctcagacaaaagaaaacatg
actttacaagccaagagctttggatcgacatgtcaattaagtgaaaaattcatcaaagct
gcaattggctgtggtattgtcgaaagcatactgaactgggtgaagtttaaggcccaaatc
cagttaaataagaagtgttcagctgtaaaacataacagaatcaagggaattcccaaactt
gatgatgccaacgatgcagggagtcgaaactccactgaatgtacacttatcctgactgag
ggagactcagccaaaactctggcagtttcaggccttggtgtagtgggaagagacaaatat
ggggtatttcctcttagaggaaaaatactcaatgtgcgagaagcttcgcataaacagatc
atggaaaatgctgaaattaacaatatcatcaagattgtgggtcttcagtacaagaaaaac
tatgaagatgaagattcattgaaaactcttcgttatggaaagataatgattatgacagat
caggaccaagatggttcccatatcaaaggcttgctgatcaattttatccatcacaactgg
ccttcgcttctgagacatcgctttctagaagaatttattactcccattgtaaaggtgtct
aaaaacaagcaagaaatggctttctatagtcttcctgagtttgaagaatggaagagttct
actccaaatcataaaaaatggaaagtcaaatattacaaaggtttgggcaccagcacatca
aaggaagctaaggaatattttgcagatatgaaaagacatcgtattcaattcaaatactct
gggcctgaagatgatgctgcaatcagtctggcctttagtaagaaacaggtcgatgatcga
aaggaatggttaactcacttcatggaagacagaagacagcgtaagttacttggccttcct
gaggattatttgtatggacaaaccactacttacctgacctataatgacttcataaacaag
gaacttatcctcttctccaattctgataatgaaagatctnatccatctatggtagatggt
ttgaaaccaggtcagagaaaagttttgtttacttgtttcaaacggaatgacaagcgagaa
gtgaaggttgcccagttagctgggtcagtggcagaaatgtcctcttatcatcatggtgag
atgtcactgatgatgaccattatcaatttggctcagaattttgtgggtagtaataatttg
aatctcttgcaacccattggtcagtttggtaccaggctgcatggtggcaaggattcagct
agtcctcgatacatctttactatgctcagccctttgactcggttgctatttccaccaaaa
gatgatcacacattaaagtttttatatgatgacaaccagcgtgtggagcctgaatggtac
attcctattatacccatggtgctgataaatggtgctgagggaattggtaccgggtggtcc
tgcaaaatccccaactttgatgtccgtgaggtggtgaataatatcagacgactgttggat
ggagaggagcccctgcccatgctcccaagctacaagaatttcaaaggtactatcgaagaa
ctggcttcaaatcagtacgtgattaatggagaagtagctattctgaattcaacaaccatt
gaaatctcagagcttcccgtcagaacatggacccagacttacaaagaacaggttctagaa
cccatgttgaatggcactgagaagacaccccctcttataacagattatagggaataccat
acagataccactgtgaggtttgtcataaagatgactgaagaaaaattggcagaggcagag
agagtgggactacacaaagtcttcaaactgcagactagtctcacttgcaactctatggtg
ctttttgaccatgtaggttgcttaaagaaatatgacactgtgctggatattctgaaagac
ttctttgagctcaggcttaaatattatggattaagaaaagaatggcttctaggaatgctt
ggtgcagaatctgctaaactgaataatcaagctcgttttatattagaaaaaatagacggc
aaaataatcattgaaaataaacctaaaaaagagttaattaaagttctaattcagagagga
tatgattccgatcctgtgaaggcctggaaagaagctcagcaaaaggttccagacgaagaa
gaaaatgaagaaagtgacaatgaaaacaatgactccgtaccagaatctggaccaactttc
aactaccttcttgatatgcccctttggtatctgaccaaggaaaagaaagatgagctgtgc
aaacagagaaatgaaaaggaacaagagctcaacacattaaagaaaaagagtccatcagat
ttgtggaaggaagatctggctgttttcattgaagaactggaggttgtcgaagccaaggag
aaacaggacgagcaagtaggacttcctggaaagggggggaaagccaagggcaagaaagga
caagtgtcggaagtcttgccttctcccgggggaaagagagtcattccccacgtcaccatg
gagatgaaagcagaggcagagaagaaaattaggaagaagattaagagtgaaaacgctgag
ggcacgcctgctgaggatggtctggaactaggaggcctaaaacagagactagcaaagaag
cagaagaaagagccagataccatggcaaagaagcaaactacattgccatttaagcccatc
aaaaaagggaagaagagaaacccctggtctgattctgaatcagatatgagcagtaatgaa
agtaattttgatgtccctccacgagaaaaagatccaagaagagctgcaacaaaagccaaa
ttcacagtcgatttggattcagatgaagacttctcaggttttgaggaaaaggatgaagat
gaagattttttcccattagatactagtccacccaagaccaaaattcccccaaaaaatagg
acaaagacactgaagacacagaagagtaccacgtctgtagctgaccttgaaagtgatgtt
caggacagtgtgccagcttctccaagccctcctgccgctgacgtcccagctgaaaaggaa
cagttaaagccatcttccaaacagactgcagcatcgaagaagacagtgaccaaaagccag
tcttcaacctccactgctggtaccaaaaagagagctgcaccaaaggcaaccaaatccgat
tcaaccttgagtgttcatggccctgaaaagcctgatcctgccaaagccaagagcaaccgc
aaaaggaagcagtcttctgatgattcagactctgattttgagaaagtagtttccaaagct
gccacgagcaagaaactcaagggagagactcaggatttccatgtggacttagatgagact
gtggctcctcgagcaaaatctggacgagcaaggaagcctattaagtacctggaggagtcg
gatgaggatgaccttttctga
DBGET
integrated database retrieval system
