Panthera leo (lion): 122199448
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Entry
122199448 CDS
T10741
Symbol
GRK2
Name
(RefSeq) beta-adrenergic receptor kinase 1 isoform X1
KO
K00910
beta-adrenergic-receptor kinase [EC:
2.7.11.15
]
Organism
plez Panthera leo (lion)
Pathway
plez04062
Chemokine signaling pathway
plez04144
Endocytosis
plez04340
Hedgehog signaling pathway
plez04724
Glutamatergic synapse
plez04740
Olfactory transduction
plez05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04340 Hedgehog signaling pathway
122199448 (GRK2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
122199448 (GRK2)
09150 Organismal Systems
09151 Immune system
04062 Chemokine signaling pathway
122199448 (GRK2)
09156 Nervous system
04724 Glutamatergic synapse
122199448 (GRK2)
09157 Sensory system
04740 Olfactory transduction
122199448 (GRK2)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
122199448 (GRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122199448 (GRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
plez04147
]
122199448 (GRK2)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.15 beta-adrenergic-receptor kinase
122199448 (GRK2)
Protein kinases [BR:
plez01001
]
Serine/threonine kinases: AGC group
GRK family [OT]
122199448 (GRK2)
Exosome [BR:
plez04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
122199448 (GRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RGS
PH
Kinase-like
DUF5647
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
122199448
NCBI-ProteinID:
XP_042760485
UniProt:
A0A8C8X5U1
LinkDB
All DBs
Position
D1:109910970..109930294
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AA seq
689 aa
AA seq
DB search
MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
QKLGYLLFRDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLARSREVFDTYIMKELLAC
SHPFSKSATEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAE
IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE
VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE
LRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARK
KTKNKQLGHEEDYALGKDCIMHGYMAKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSL
LTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQR
VPKMKNKPRSPVVELSKVPLVQRGSANGL
NT seq
2070 nt
NT seq
+upstream
nt +downstream
nt
atggcggacctggaggcggtgctggccgatgtgagctacctgatggccatggagaagagc
aaggccacgccggccgcgcgcgccagcaagaagatcctgctgcccgaacccagcatccga
agcgtcatgcagaagtacctggaagaccggggcgaggtgacctttgagaagatcttctcc
cagaagctggggtacctgctcttccgagacttctgcctgaaacacctagaggaggccaag
ccgttggtggagttctatgaggagatcaagaaatacgagaagctggagacagaggaggag
cgcttggctcgcagccgggaggtcttcgacacctacatcatgaaggagctgctggcctgc
tcacaccccttctcgaaaagtgccactgagcacgtccagggccacctggtgaagaagcag
gttcctccggatctcttccagccatacattgaagagatttgtcagaacctccgaggggat
gtgttccagaaattcatcgagagcgataaattcacacgattttgccagtggaagaatgtg
gagctcaacatccatctgaccatgaacgacttcagcgtgcaccgcatcatcggacgaggg
ggcttcggcgaggtctatgggtgccggaaggccgacacgggcaagatgtacgccatgaag
tgtctggataagaagcgcatcaagatgaagcagggggagaccctggccctgaacgagcgc
atcatgctgtccctcgtcagcactggggactgcccgttcatcgtgtgcatgtcgtacgca
ttccacacgccggacaagctcagcttcatcctcgatctcatgaacggcggggacctgcac
taccacctgtcccagcacggggttttctccgaggccgacatgcgcttctacgcggccgag
atcatcctgggcctggagcacatgcacaaccgcttcgttgtctatcgggacctgaagcca
gccaacatccttctggacgagcacggtcacgtgcgcatctcagacctcggcctggcctgc
gacttctccaagaagaagccccacgccagcgtgggcacccacgggtacatggcccctgag
gtcctgcagaagggcgtggcctacgatagcagcgctgactggttctccctgggctgcatg
cttttcaagttgctgcgggggcacagcccctttcggcagcacaagaccaaagataagcac
gagattgaccgcatgacattgacgatggctgtggagctgcccgactccttctcccccgag
ctccgttccttgctggaggggctgctgcagagggatgtcaaccggagactgggctgcctg
ggtcgaggggcccaggaggtaaaggagagccccttcttccgctccttggactggcaaatg
gtcttcttgcagaagtaccctcccccgctgatcccccctcgaggggaggtgaacgctgct
gacgccttcgacattggctcctttgacgaggaggacacaaaaggaatcaagttgctggac
agtgaccaggaactctaccgcaacttccccctcaccatctcggagcggtggcagcaggag
gtggcggagacggtcttcgacaccatcaatgccgagaccgaccggctggaggcccgcaag
aaaaccaaaaacaagcagttgggccacgaggaagactacgccctgggcaaggactgcatc
atgcatggctacatggccaagatgggcaaccccttcctgacgcagtggcagaggcggtac
ttctacttgttccccaaccggctggagtggcggggcgagggcgaggccccgcagagcctg
ctgaccatggaggagatccagtctgtggaggagacgcagatcaaggagcggaagtgcctc
cttctcaagatccgcggcggcaaacagtttgtgctgcagtgcgacagcgaccctgagctg
gtgcagtggaagaaggagcttcgggacgcgtaccgcgaggcccagcagctggtgcagcgc
gtgcccaagatgaagaacaagccgcgctcgcccgtggtggagctgagcaaggtgccgctg
gtccagcgcggcagtgccaacggcctctga
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