Panthera leo (lion): 122199514
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Entry
122199514 CDS
T10741
Symbol
CAPN1
Name
(RefSeq) calpain-1 catalytic subunit
KO
K01367
calpain-1 [EC:
3.4.22.52
]
Organism
plez Panthera leo (lion)
Pathway
plez04141
Protein processing in endoplasmic reticulum
plez04210
Apoptosis
plez04217
Necroptosis
plez04218
Cellular senescence
plez04382
Cornified envelope formation
plez05010
Alzheimer disease
plez05022
Pathways of neurodegeneration - multiple diseases
Brite
Enzymes [BR:
plez01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.22 Cysteine endopeptidases
3.4.22.52 calpain-1
122199514 (CAPN1)
Peptidases and inhibitors [BR:
plez01002
]
Cysteine peptidases
Family C2: calpain family
122199514 (CAPN1)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_C2
Calpain_III
EF-hand_6
EF-hand_1
EF-hand_8
EF-hand_7
CAPN13-like_C_EFh
Motif
Other DBs
NCBI-GeneID:
122199514
NCBI-ProteinID:
XP_042760568
UniProt:
A0A8C8XWT4
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Position
D1:108115435..108142617
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AA seq
716 aa
AA seq
DB search
MAEEIITPVYCTGVSAQVQKQRAKELGLGRHENAIKYMGQDYEQLRAHCLQSGVLFRDEA
FPPVPQSLGYKDLGLNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAA
IASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHS
AQGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILK
ALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYQGQMVSLIRMRNPWGE
VEWTGAWSDGSSEWNNVDPYEREQLRIKMEDGEFWMSFRDFLREFSRLEICNLTPDALKS
RSIRKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEETDDADDDYYGGRESGCS
FVLALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANSSRARSEQFI
NLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKKAGTEELDDQIQANLPDEQVL
SEEEIDENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMD
RDGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYEL
IITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA
NT seq
2151 nt
NT seq
+upstream
nt +downstream
nt
atggccgaggaaatcatcaccccggtgtactgcacgggggtgtctgcacaagtgcagaag
cagcgggccaaggagctgggccttggccgccatgaaaatgccatcaagtacatgggccag
gattatgagcagctgcgggctcactgtctgcagagtggggtcctctttcgtgatgaggcc
ttccccccggtgccccagagcctgggctacaaggacctgggcctcaactcctccaaaacc
tatggcatcaagtggaagcgtcccacggagctgctctcaaacccccagttcattgtggat
ggagccacacgcacagacatctgccagggagcactgggggactgttggctcctggctgcc
attgcctccctcacccttaatgacacgcttctgcatcgagtggttccacatggccaaagc
ttccagaatggctatgccggcatctttcatttccagctgtggcagtttggggaatgggta
gatgtggttgtggatgacctactgcccatcaaggacgggaagctggtgtttgtgcactcc
gcccaaggcaatgagttctggagcgccctgctcgagaaggcctatgccaaggtgaatggc
agctacgaggccctctccgggggcagcacttcggagggctttgaggacttcacaggcgga
gtcaccgagtggtatgagctgcgcaaggcacccagcgacctctaccagatcatcctcaag
gcgctcgagcgaggttccctcctgggctgctccatcgacatctccagtgtcctggacatg
gaggccatcaccttcaagaagctggtgaagggccacgcctactctgtgacgggggccaag
caggtgaactaccagggccagatggtgagcctgatccggatgcggaatccctggggcgag
gtggagtggacgggagcctggagcgacggctcctcggagtggaacaacgtggacccttac
gagcgggagcagctccggatcaagatggaggatggagagttctggatgtccttccgagac
ttcttgcgtgagttctcccgcctggagatctgcaacctgacgcccgacgcgctcaagagc
cggtccatccgcaaatggaacaccacgctctacgagggcacctggcggcgggggagcacc
gcggggggctgccggaactacccagccaccttctgggtcaatccccagttcaagatccga
ctggaggagacggatgacgcggacgacgactactacgggggtcgagaatcaggctgcagc
ttcgtgctagccctcatgcagaagcaccgccgccgtgagcgccgctttggccgcgacatg
gagaccatcggcttcgccgtctacgaggttcctccggagctggtgggccagccggccgtg
cacctgaagcgcgacttcttcctggccaactcgtcgcgggcgcgctcagagcagttcatc
aacttgcgggaggtcagcacccgcttccgcttgccgcccggggagtacgtggtggtgccc
tccaccttcgagcccaacaaggagggcgacttcgtgctacgcttcttctcggagaagaag
gccgggaccgaggagctggacgaccagatccaggccaatctccctgatgagcaagtgctc
tcagaagaggagattgatgagaacttcaaggccctctttaggcagctggcaggggaggac
atggagatcagcgtcaaggaactgcggaccatcctcaacaggatcatcagcaaacacaag
gacctgcggacaaagggcttcagcctggagtcgtgccgcagcatggtgaacctcatggac
cgggacggcaacgggaagctgggcctggtggagttcaacatcctgtggaaccgcatccgg
aattacctgtccatcttccggaagtttgacttggacaagtcgggcagcatgagtgcctac
gagatgcggatggccatcgagtctgcgggcttcaagctcaacaagaagctgtatgaactc
attatcacccgctactcggagcccgacctggccgtggactttgacaacttcgtgtgctgc
ctggtgcggctggagaccatgttccggtttttcaaaactctggacacagatctggacggg
gtggtgacctttgacttgtttaagtggttacagctgaccatgtttgcatga
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