KEGG   Panthera leo (lion): 122199546
Entry
122199546         CDS       T10741                                 
Symbol
MRE11
Name
(RefSeq) double-strand break repair protein MRE11 isoform X1
  KO
K10865  double-strand break repair protein MRE11
Organism
plez  Panthera leo (lion)
Pathway
plez03440  Homologous recombination
plez03450  Non-homologous end-joining
plez04218  Cellular senescence
Brite
KEGG Orthology (KO) [BR:plez00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    122199546 (MRE11)
   03450 Non-homologous end-joining
    122199546 (MRE11)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    122199546 (MRE11)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:plez03032]
    122199546 (MRE11)
   03400 DNA repair and recombination proteins [BR:plez03400]
    122199546 (MRE11)
DNA replication proteins [BR:plez03032]
 Eukaryotic type
  DNA Replication Termination Factors
   MRN complex
    122199546 (MRE11)
DNA repair and recombination proteins [BR:plez03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    MRN(MRX) complex
     122199546 (MRE11)
    BRCA1-C complex
     122199546 (MRE11)
   NHEJ (non-homologous end-joining)
    MRX complex
     122199546 (MRE11)
SSDB
Motif
Pfam: Mre11_DNA_bind Metallophos
Other DBs
NCBI-GeneID: 122199546
NCBI-ProteinID: XP_042760625
LinkDB
Position
D1:39049058..39126268
AA seq 708 aa
MSPADALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTFDEILRLAQENEVDFILLGGD
LFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDDNLNISI
PVFSIHGNHDDPTGADALCALDILSCAGFVNHFGRSVSVEKIDISPVLLQKGSSKIALYG
LGSIPDERLYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGNTNFIPEQFLDDFIDL
VIWGHEHECKIAPTKNEQQLFYVSQPGSSVVTSLSPGEAVKKHVGLLRVKGRKMNMQKIP
LHTVRQFFMEDIVLADHPDIFNPDNPKVTQAIQSFCLEKIKEMLENAERERLGNSRQPEK
PLIRLRVDYSGGFEPFSVLRFSQKFVDRVANPKDVIHFFRHREQKENTGEEINLGKLITK
PSEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEK
TQRFLKERHIDALEDKIDEEVRRFRESRQKNTNEEDDEVREAMTRARALRSQSEDSASAF
SAEDLMSIDLAEQMADDSDDDITAAANKGRGRGRGRRGRGQSSASRGGSQRGRGGSSLDT
STRSRSSKAAVSTSRNMSIIDAFKSTRPQPSRNVATKNYTEMIVDETDEEEDMFPTTSKT
EQRCPSTSSSSSKRMSQSQIAKGVDFESDEDDDDDPFMNTSSLRGNRR
NT seq 2127 nt   +upstreamnt  +downstreamnt
atgagtcctgcagatgcccttgacgatgaaaatacatttaaaatcttagttgcaacagat
attcatctgggatttatggagaaagatgcagtcagaggaaatgacacatttgtaacattt
gatgagattttaagacttgcccaggaaaatgaagtggattttattttgttaggtggtgat
ctttttcatgaaaataagccctcaagaaaaacattacatacctgcctcgagttattgaga
aaatattgcatgggtgatcgtcctgtacagtttgaaattctcagtgatcagtcagtcaac
tttggttttagtaagtttccgtgggtgaactaccaagatgacaatctcaacatttcgatt
ccagtgttcagtattcatggcaatcatgatgatcccacaggggcagatgccctgtgtgcc
ctggacatactaagctgtgctggatttgtaaatcactttggacgttcagtgtctgtggag
aagatagacattagtccagttttgctccaaaaaggaagctccaaaattgctttatatggc
ttagggtccattccagatgaaaggctctatcgaatgtttgtcaataaaaaggtaacaatg
ttgagaccaaaagaagatgagaactcttggtttaacttatttgtgattcatcagaacagg
agtaaacacggaaatactaacttcattccagaacaatttttggatgacttcattgatctt
gttatatggggccatgaacatgagtgtaaaatagctccaaccaaaaatgaacaacaactc
ttttatgtatcacaacctggaagttcagtggttacttctctttccccaggagaggctgta
aagaagcatgttggtttgctgcgcgttaagggaaggaagatgaatatgcagaaaattcct
ctccacacggtgcggcagttttttatggaggatattgttctggccgatcatccagacatt
tttaacccagataatcctaaagtaacccaggccatacaaagcttttgtttggagaagatt
aaagaaatgcttgaaaatgctgagcgagaacgtctgggaaactctcgacagccagagaag
cctctcatacgacttcgagtggactatagtggaggttttgaacctttcagtgttcttcgc
tttagccagaaatttgtggatcgggtagctaacccaaaagatgttatccattttttcagg
cacagagaacaaaaggagaacacaggagaagaaatcaacttagggaagttaatcacaaaa
ccttcagaaggcacaactctaagagtagaagaccttgtaaaacagtattttcaaactgcg
gaaaagaatgtgcagctctcacttctaaccgaaaggggaatgggcgaagcagtacaagaa
tttgtggacaaggaagaaaaagatgccatagaggaattagtgaaataccaattggaaaaa
acacagcgatttcttaaagaacgtcatattgatgccttagaagataaaatcgacgaagag
gtacgccgtttcagagaaagcaggcaaaaaaacactaatgaagaagatgatgaagttcga
gaggctatgactagggccagagccctcagatctcagtccgaggactctgcttccgccttt
agtgctgaggaccttatgagtatagatctggcagaacagatggctgatgactctgatgat
gacatcacagcagcagccaacaaaggaagaggccgaggaagaggccgacggggaagaggg
cagagttcagcctcgagaggagggtctcagagaggaagaggaggcagtagtctggatact
tctactcgaagcagaagttcaaaggctgctgtgtcaacatctagaaatatgtctattata
gatgcctttaaatctacaagaccgcagccttcccgaaatgttgctactaagaattataca
gagatgattgtggatgagacagatgaagaagaagacatgtttcctaccacttcaaaaaca
gagcagaggtgtccgagcacatcatcatcatcaagcaagcgcatgtcccaaagccaaata
gctaaaggggtcgattttgaatcagatgaggatgacgacgatgatccttttatgaacact
agctctttaagaggaaacagaagataa

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